Sparse Gene Coexpression Network Analysis Reveals EIF3J-AS1 as a Prognostic Marker for Breast Cancer by Xin Chen, Zuyuan Yang, Chao Yang, Kan Xie, Weijun Sun, Shengli Xie

“…One lncRNA, EIF3J-AS1, is significantly associated with clinicopathological characteristics, including tumor size, lymph node metastasis, estrogen receptor (ER), and progesterone receptor (PR) status. …”
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Primary Intraosseous Synovial Sarcoma with Molecular Confirmation: Expanding and Clarifying the Spectrum of This Rare Neoplasm by Kelsey E. McHugh, John D. Reith, Nathan W. Mesko, Scott E. Kilpatrick

“…Clinical follow-up data was only available for the female patient with the primary humeral lesion, who underwent surgical resection, with no local recurrence or distant metastasis at 7 months postsurgery. To our knowledge, these are the first reported examples of molecularly confirmed, primary intraosseous synovial sarcomas of the humerus and metatarsal bones. …”
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Therapeutic implications and comprehensive insights into cellular senescence and aging in the tumor microenvironment of sarcoma by Pengfei Zan, Yi Zhang, Yidong Zhu, Qingjing Chen, Zhengwei Duan, Yonghao Guan, Kaiyuan Liu, Anquan Shang, Zihua Li

“…Emerging evidence indicates that senescent cells within the tumor microenvironment (TME) significantly contribute to cancer progression and metastasis. Although the influence of senescence on SARC has been partially acknowledged, it has yet to be fully elucidated. …”
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Intravitreal Melphalan for Vitreous Seeds: Initial Experience in China by Xunda Ji, Peiyan Hua, Jing Li, Jiakai Li, Junyang Zhao, Peiquan Zhao

“…There was no case of epibulbar extension or systemic metastasis within the period of follow-up. Conclusion. …”
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Ascorbic acid-immobilized zinc selenide for electrochemical monitoring of hydrogen peroxide in liver cancer samples by Shan E Zahra Jawad, Sibtain Ahmed, Dilshad Hussain, Javerya Najeeb, Ayub Alam, Muhammad Najam-ul-Haq, Batool Fatima

“…Hydrogen peroxide (H2O2), an emerging biomarker is a powerful oxidant found in the tumor microenvironment, and stimulates the invasion, proliferation, and metastasis of liver cancer cells. This study describes a medically effective and sensitive electrochemical sensor based on ascorbic acid immobilized zinc selenide nanoparticles (AsA@Zn-Se NPs) decorated on a glassy carbon electrode (GCE) for determining H2O2 in PBS and human serum samples of liver cancer patients. …”
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Multiomics analysis reveals the involvement of NET1 in tumour immune regulation and malignant progression by Jian Pang, Xiaoyan Huang, Ya Gao, Xinyu Guan, Lejia Xiong, Lun Li, Nana Yin, Mei Dai, Tong Han, Wenjun Yi

“…Research has shown that NET1 can regulate the malignant biological functions of tumour cells, such as growth, invasion, and metastasis, and it is closely related to the progression of pancreatic cancer, gastric cancer, and liver cancer. …”
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LcProt: Proteomics‐based identification of plasma biomarkers for lung cancer multievent, a multicentre study by Hengrui Liang, Runchen Wang, Ran Cheng, Zhiming Ye, Na Zhao, Xiaohong Zhao, Ying Huang, Zhanpeng Jiang, Wangzhong Li, Jianqi Zheng, Hongsheng Deng, Yu Jiang, Yuechun Lin, Yun Yan, Lei Song, Jie Li, Xin Xu, Wenhua Liang, Jun Liu, Jianxing He

“…We utilised Zeolite Zotero NaY‐based plasma proteomics to investigate its potential for multiple event predicting, including lung cancer diagnosis (task #1), lymph node metastasis detection (task #2) and tumour‒node‒metastasis (TNM) staging (task #3). …”
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Role of Magnetic Resonance Spectroscopy and Diffusion-weighted Imaging in the Evaluation of Supratentorial Brain Tumours with Histopathology Correlation at a Tertiary Care Hospital... by Kotireddy Pavan Kumar Reddy, Rajalingam Venkat Sai, R. Archana, Sarala Devi, Sunitha Bajaj, Valluru Naga Lakshmi Vaishali

“…In addition, mean apparent diffusion coefficient values showed significant differences between primary low-grade tumours (1.1), primary high-grade tumours (0.87) and metastasis (0.855). Conclusion: This study underscores gender-related differences in supratentorial tumour susceptibility and highlights distinct tumour distributions based on grades. …”
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Endometrial Cancer Cells Promote M2-Like Macrophage Polarization by Delivering Exosomal miRNA-21 under Hypoxia Condition by Li Xiao, Yumin He, Fan Peng, Jianlin Yang, Chengfu Yuan

“…Increasing evidence has demonstrated that hypoxia was an aggressive feature in endometrial cancer (EC), which is significantly associated with the tumor grade, lymph node metastasis, and tumor resistance to chemotherapy. However, the relationship between hypoxia and the immune microenvironment in EC is not very clear. …”
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Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on P... by Mpho Ndou, Marthe C. D. Fotsing, Michael H. K. Kengne, Edwin M. Mmutlane, Derek T. Ndinteh, Mthokozisi B.C. Simelane, Lesetja Motadi, Mpho Choene

“…Wound healing showed a decreased cell migration on both cell lines an important stage of metastasis. The study suggests that the study molecule can be a promising chemotherapeutic agent in the development of new anticancer drugs. …”
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APOC1 knockdown induces apoptosis and decreases angiogenesis in diffuse large B-cell lymphoma cells through blocking the PI3K/AKT/mTOR pathway by Jing Gao, Xiaojuan Lu, Guanglei Wang, Tanling Huang, Zhongyu Tuo, Weiwei Meng

“…Apolipoprotein C1 (APOC1) plays a significant role in the proliferation and metastasis of various malignant tumors; however, its role in DLBCL—particularly its effects on angiogenesis—remains largely unexplored. …”
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Clinicopathologic Significance of CXCL12 and CXCR4 Expressions in Patients with Colorectal Cancer by Naomi Yoshuantari, Didik Setyo Heriyanto, Susanna Hilda Hutajulu, Johan Kurnianda, Ahmad Ghozali

“…The prognosis of CRC is affected by various factors like the histological grade, angiolymphatic invasion, and distant metastases. Metastasis is an intricate process; one of the possible mechanisms is through the interaction of the chemokines CXCL12 and CXCR4. …”
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Cancer-associated fibroblasts and their role in tumor progression by M. S. Ermakov, A. A. Nushtaeva, V. A. Richter, O. A. Koval

“…The stromal elements of a malignant tumor can promote cancer progression and metastasis. The structure of the tumor stroma includes connective tissue elements, blood vessels, nerves, and extracellular matrix (ECM). …”
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Comparison of Morphological and Functional MRI Assessments of Periprostatic Fat for Predicting Prostate Cancer Aggressiveness by David Freire Maia Vieira, Cecília Vidal de Souza Torres, André de Freitas Secaf, Matheus de Moraes Palma, Gabriel de Lion Gouvea, Jorge Elias Júnior, Rodolfo Borges Reis, Valdair Muglia

“…Clinical and MRI parameters were analyzed for associations with biochemical recurrence, systemic metastasis, and PCa-related mortality. Results: After applying exclusion criteria, 109 patients were included. …”
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Snail Expression is Positively Correlated with Depth of Invasion in Colorectal Carcinoma by Upik Anderiani Miskad, Fardah Akil, Muhammad Husni Cangara, Haslindah Dahlan, Gina Andyka Hutasoit, Muhammad Riza Ilyasa

“…Meanwhile, Snail expression is positively correlated with tumor grade, recurrence, metastasis and poor prognosis in various tumors. However, not many studies discuss the correlation of Snail expression with invasion depth and TILs in Indonesia. …”
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Different Anatomical Subsites of Colon Cancer and Mortality: A Population-Based Study by Xing-kang He, Wenrui Wu, Yu-e Ding, Yue Li, Lei-min Sun, Jianmin Si

“…We demonstrated that LCC was associated with better prognosis, especially for patients with distant metastasis. Future trails should seek to identify the underlying mechanism.…”
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A case of subcutaneous metastatic malignant melanoma of the left medial ankle: a case report and review of literature by Lauren Workman, Lauren Fang, Martina Blazevic, Joanna Chen, Richard Simman

“…Several hypotheses have been proposed for how melanoma of unknown primary develops, two of which were considered in our patient case: (1) spontaneous regression of the primary tumor following metastasis or (2) the traumatic implantation of ectopic melanocytic cells in other tissues, such as the subcutaneous tissue. …”
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Optimizing the NGS-based discrimination of multiple lung cancers from the perspective of evolution by Ziyang Wang, Xiaoqiu Yuan, Kunkun Sun, Fang Wu, Ke Liu, Yiruo Jin, Olga Chervova, Yuntao Nie, Airong Yang, Yichen Jin, Jing Li, Yun Li, Fan Yang, Jun Wang, Stephan Beck, David Carbone, Guanchao Jiang, Kezhong Chen

“…Abstract Next-generation sequencing (NGS) offers a promising approach for differentiating multiple primary lung cancers (MPLC) from intrapulmonary metastasis (IPM), though panel selection and clonal interpretation remain challenging. …”
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Cell-membrane targeting sonodynamic therapy combination with FSP1 inhibition for ferroptosis-boosted immunotherapy by Jian Chen, Qiyu Zhan, Lie Li, Simin Xi, Longmei Cai, Ruiyuan Liu, Lujia Chen

“…Moreover, the as-synthesized TiF NPs-mediated cell membrane targeting SDT/FSP1 inhibition thoroughly inhibited the tumor growth and simultaneously activated antitumor immunity to suppress lung metastasis. This work represents a promising tumor therapeutic strategy combining cell membrane targeting SDT and FSP1 inhibition, potentially inspiring further research in developing logical and effective cancer therapies based on synergistic SDT/ferroptosis.…”
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Guiding Sole Intraoperative Radiotherapy in Breast Cancer According to ASTRO Guidelines: Mitigating Adverse Outcomes in a Taiwan Single‐Center by Hsin‐Yi Yang, Yuk‐Wah Tsang, Chi‐Wen Tu, Yu‐Chen Hsu

“…Results ASTRO‐suitable patients had significantly lower rates of LRR (0.00% vs. 10.64%), distant metastasis (0.00% vs. 4.00%), and any recurrence (0.00% vs. 7.79%) than non‐suitable patients (p < 0.05). …”
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