Function of vasohibin-2 and the mechanism of alternative splicing in triple-negative breast cancer by WANG Wei, WANG Hongli, ALIBIYATI·i Ain, YILIYAER· Rousu, NUER AYI, YANG Liang

“…Objective·To explore the role of vasohibin-2 (VASH2) in the regulation of proliferation and metastasis of triple-negative breast cancer (TNBC) cells, and explore the mechanism of VASH2 in the occurrence and development of TNBC through regulation of gene expression and alternative splicing.Methods·TCGA-GTEx was used to analyze the expression of VASH2 in TNBC. …”
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Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer by Xiaolong Liu, Pengxian Tao, He Su, Yulan Li

“…Abstract Gastric cancer (GC) is one of the most common tumors; one of the reasons for its poor prognosis is that GC cells can resist normal cell death process and therefore develop distant metastasis. Cuproptosis is a novel type of cell death and a limited number of studies have been conducted on the relationship between cuproptosis-related genes (CRGs) in GC. …”
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Clinicopathological Features and Prognoses of Patients With Splenic Metastases From Breast Cancer: A Single-Centre, Retrospective Study by Xiaofeng Xie MD, Mingrui Ma MD, Xue Bai BS, Jing Hu MD, Haijie Zheng MD, Xiongqi Guo BS, Jiayi Huang MD, Xuelian Chen PhD, Liping Chen BS, Xiaofeng Lan BS, Lin Song BS, Caiwen Du PhD

“…Clinicopathological characteristics and their associations with progression-free survival (PFS [time from diagnosis of initial recurrence and/or metastasis to diagnosis of SM]), first overall survival ( 1st OS [time from diagnosis of breast cancer to death or last follow-up visit]), and second overall survival ( 2nd OS [time from diagnosis of SM to death or last follow-up visit]) were analysed in patients with SMBC. …”
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Metastatic Malignant Ectomesenchymoma Initially Presenting as a Pelvic Mass: Report of a Case and Review of Literature by A. Nael, P. Siaghani, W. W. Wu, K. Nael, Lisa Shane, S. G. Romansky

“…He is currently off from any treatment for 18 months with no evidence of tumor recurrence or metastasis.…”
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Interplay between Body Size Measures and Thyroid Cancer Aggressiveness: A Retrospective Analysis by Thaís Gomes de Melo, Ligia Vera Montali da Assumpção, Denise Engelbrecht Zantut-Wittmann

“…Women with poorly differentiated tumor and patients aged ≥45 years old with distant metastasis presented greater weight loss during follow-up compared to patients without such characteristics (median −2 kg versus +1.5 kg and −3 kg versus +1 kg, respectively). …”
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The Impact of Metastatic Bone Cancers on Serum Calcium Levels: A Focused Analysis of Patient Outcomes by Muhammad Khizar Memon, Syed Uzair Mahmood, Sidra Memon, Azhar Rashid, Muhammad Ali Memon, Shahzad Ali Jiskani

“… Background: Metastatic bone cancers are a significant clinical problem because metastasis disrupts normal bone homeostasis, including calcium dysregulation. …”
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Metastatic brain tumors: from development to cutting‐edge treatment by Guilong Tanzhu, Liu Chen, Jiaoyang Ning, Wenxiang Xue, Ce Wang, Gang Xiao, Jie Yang, Rongrong Zhou

“…Abstract Metastatic brain tumors, also called brain metastasis (BM), represent a challenging complication of advanced tumors. …”
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A Papillary Thyroid Microcarcinoma Revealed by a Single Bone Lesion with No Poor Prognostic Factors by Yann Godbert, Benedicte Henriques-Figueiredo, Anne-Laure Cazeau, Xavier Carrat, Marc Stegen, Isabelle Soubeyran, Francoise Bonichon

“…This extremely rare case of a singular bone metastasis revealing a papillary thyroid microcarcinoma illustrates the necessity of further research to better characterize the forms of papillary thyroid microcarcinomas with potentially poor prognosis.…”
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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

“…Cohort analysis revealed a significant positive correlation between metastasis rate and radiotherapy use (Spearman's rho = 0.828, p = 0.042) and between chemotherapy and hormonal therapy use (rho = 0.69, p = 0.04). …”
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Unexpected encounters: The surprising link between ovarian cancer and axillary lymphadenopathy by Marina Balbino, Federica Masino, Manuela Montatore, Francesca Anna Carpagnano, Giuseppe Guglielmi

“…The axillary tru-cut biopsy histological examination revealed ovarian metastasis. The total body computed tomography (CT) scan and pelvic MRI confirmed the presence of a left ovarian tumor. …”
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T cell receptor signaling pathway subgroups and construction of a novel prognostic model in osteosarcoma by Huan Xu, Huimin Tao

“…A nomogram comprising metastasis and risk score was successfully built. The sensitivity to chemotherapy agents were different across high and low risk groups. …”
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Circulating Oxidized Low-Density Lipoproteins and Antibodies against Oxidized Low-Density Lipoproteins as Potential Biomarkers of Colorectal Cancer by Dorota Diakowska, Krzysztof Grabowski, Mirosław Nienartowicz, Paweł Zarębski, Kamila Fudalej, Krystyna Markocka-Mączka

“…Serum CEA levels were significantly elevated in the advanced stage of disease, primary tumor progression, angiolymphatic invasion, and presence of distant metastasis. Conclusions. Obtained results have demonstrated that oxLDL and o-LAB were not satisfactory risk markers of CRC. …”
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Investigating orbital foreign device-associated malignancies: a scoping review by Jeong Hyun Ha, Jagmeet S. Arora, Jamasb J. Sayadi, Nada R. Khattab, Shannon D. Francis, Thomas M. Johnstone, Yeonji Jang, Gordon K. Lee

“…These malignancies varied in characteristics and demographics, with some showing metastasis or local invasion. The median time to tumor development was 40 years. …”
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Association between alkaline phosphatase levels and mortality in Chinese patients with colorectal cancer with liver metastases: a retrospective cohort study by ZhaoXi Liu, ZiQing Zhang, GuoFang Yu, MingJiang Mo, ChuanYu Xie, DangHan Xu, JieTao Lin, YuChen Zhang, Li Deng, YiChang Luo, YingFeng Huang, Cui Shao

“…However, its prognostic value in patients with colorectal liver metastasis remains unclear. Objectives: This study aimed to investigate the association between ALP levels and mortality risk in patients with colorectal liver metastases (CRLM), providing insights for enhancing prognostic assessments. …”
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Exosomes Derived from SW480-Resistant Colon Cancer Cells Are Promote Angiogenesis via BMP-2/Smad5 Signaling Pathway by Song Yang, Lei Yao, Xiaolong Wang, Hao Sun, Chaogang Du, Chengpeng Song, Jingyu Fu, Yongjun Wu, Hongwu Huang, Chuansi Wang, Yongsen Wang, Yixiang Xie

“…Multidrug resistance is the main cause of tumor recurrence and metastasis. Therefore, it is urgent to explore the mechanism and treatment of drug resistance of tumor cells. …”
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Incidental Adrenal Enlargement: An Overview from a Retrospective Study in a Chinese Population by Le-le Li, Wei-jun Gu, Jing-tao Dou, Guo-qing Yang, Zhao-hui Lv, Yi-ming Mu, Ju-ming Lu

“…Biochemical and functional evaluation revealed 54 (69.23%) cases of nonfunctional lesions, 12 (15.38%) of subclinical Cushing syndrome, 6 (7.69%) of primary hyperaldosteronism, 1 (1.28%) of metastasis, and 5 (6.41%) of unknown functional status. …”
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Metastatic Small Cell Carcinoma of the Urinary Bladder That Recurred in the Vagina 6 Years after Radical Cystectomy: A Case Report by Makoto Isono, Keiichi Ito, Shinsuke Hamada, Masahiro Takahashi, Hidenori Sasa, Hideyuki Shimazaki, Tomohiko Asano

“…Local recurrence and metastasis at the pelvic bone occurred 4 months later; although radiation therapy was performed, she died of the progressive disease.…”
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Combination therapy of low-dose radiotherapy and immunotherapy in advanced metastatic nasopharyngeal carcinoma: a case report and literature review by Chun-Qiao Chen, Hui Huang, Min Pan, Zhe Jia, Jing Zhang, Qiu-Qiu Chen

“…The initial treatment procedure was as follows: chemotherapy regimen (nedaplatin + docetaxel + fluorouracil) induction, followed by radical radiotherapy for the primary lesion, LDRT for the L5 vertebral body metastasis, and concurrent use of low-dose capecitabine beat chemotherapy and toripalimab immunotherapy. …”
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lncRNA, miRNA, and mRNA of plasma and tumor-derived exosomes of cardiac myxoma-related ischaemic stroke by Lin Ma, Yu-Hua Liu, Chun Liu, Shu-Qi Wang, Jun Ma, Xiao-Qing Li, Min Ren, Ting-Ting Yang, Guang-Zhi Liu

“…Tumour-derived exosomes play a crucial role in tumour growth, metastasis, immune regulation, and monitor disease development. …”
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New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine by Minghui Zhang, Minghui Zhang, Zongao Wang, Zongao Wang, Shaojun Liu, Shaojun Liu, Yuxuan Li, Yuxuan Li, Yanting Gong, Yanting Gong, Min Liu, Min Liu

“…In this paper, we review the expression and significance of TRPV1 receptor in various cancer cell types, the role of TRPV1 in the apoptosis-proliferation balance, cancer cell invasion and metastasis, and tumor micro-environment, with emphasis on the mechanisms by which TRPV1 receptor mediates inflammatory response, immune system, and thus regulates cancer. …”
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