A Rare Subcutaneous Manifestation of Metastatic Renal Cell Carcinoma by Darren Yak Leong Chan, Wei Jin Chua

“…The bone scan confirmed that the forehead lump was a calvarial metastasis and such a presentation for metastatic RCC is very rare which bears a significantly poorer prognosis.…”
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Primary Small Cell Carcinoma of the Larynx: Report of a Rare Tumor by Harmeet Singh, Ashok Chauhan

“…We report a case of a 60-year-old patient with small cell carcinoma of the subglottic larynx, who presented with hepatic metastasis.…”
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A Rare Case of Metastatic Malignant Melanoma to the Colon from an Unknown Primary by Preethi Reddy, Courtney Walker, Bianca Afonso

“…The rarity of MUP and importance of screening for gastrointestinal metastasis in patients with malignant melanoma are discussed along with the role of surgical resection in improving prognosis and overall survival.…”
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(−)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells by Lumin Yang, Yuying Fang, Yufeng He, Jinsong Zhang

“…QSOX1 is a secreted disulfide catalyst, and it is widely recognized that extracellular QSOX1 promotes the growth, invasion, and metastasis of cancer cells through its participation in the establishment of extracellular matrix. …”
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Efficacy and safety of proton radiotherapy in treating choroidal melanoma: a systematic review and meta-analysis by Yuxin Miao, Tingwei Zheng, Qiuning Zhang, Meixuan Li, Qihang Lei, Qin Liu, Hongtao Luo, Huiling Bai

“…The outcomes of interest included overall survival (OS), metastasis-free survival, local control rate, and adverse reactions. …”
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Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

“…It is thought that given the role of <i>Fn</i> in tumor formation and metastasis processes via its FadA, FapA, Fap2, and RadD, new therapies for tumor treatment targeting <i>Fn</i> will be developed.…”
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Utility and clinical significance of endoscopic ultrasound-guided tissue acquisition for diagnosing lymphadenopathies in biliary tract cancer by Katsuhiko Sato, Minoru Shigekawa, Syuhei Yamamoto, Takayuki Matsumae, Yu Sato, Teppei Yoshioka, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara

“…Thirteen of 16 FNA cytology-positive patients who were diagnosed with preoperative regional lymph node metastasis received chemotherapy prior to surgery. All seven FNA cytology-positive patients who were diagnosed with distant metastasis received systemic chemotherapy. …”
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Successful thoracoscopic-assisted resection of a functional paraganglioma in the mediastinum with extracorporeal circulation: a case report by Zhihui Yang, Xiaojie Huang, Danting Zhou, Tao Tang, Hengxing Liang, Wenliang Liu, Fenglei Yu, Chen Chen

“…Lifelong surveillance is recommended to detect potential recurrence or metastasis. Effective collaboration within a multidisciplinary team is essential for ensuring accurate diagnosis and delivering optimal, individualized care.…”
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RNA modifications in cancer by Han Wu, Shi Chen, Xiang Li, Yuyang Li, He Shi, Yiwen Qing, Bohe Shi, Yifei Tang, Zhuoyi Yan, Yang Hao, Dongxu Wang, Weiwei Liu

“…This review comprehensively examines the role RNA modifications play in cancer proliferation, metastasis, and programmed cell death, including apoptosis, autophagy, and ferroptosis. …”
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Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer by Xiaoli Zeng, Xiaoli Zeng, Xiaoli Zeng, Yue Chen, Yue Chen, Jing Wang, Jing Wang, Miao He, Miao He, Junyao Qiu, Yun Huang

“…Oral cancer is a highly malignant disease characterized by recurrence, metastasis, and poor prognosis. Autophagy, a catabolic process induced under stress conditions, has been shown to play a dual role in oral cancer development and therapy. …”
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Risk Factors for Contralateral Occult Papillary Thyroid Carcinoma in Patients with Clinical Unilateral Papillary Thyroid Carcinoma: A Case-Control Study by Liu Yihao, Li Shuo, Xi Pu, Wang Zipeng, Sun Hanlin, Chang Qungang, Wang Yongfei, Yin Detao

“…Patients with multifocality in one lobe, intact capsule, central lymph node metastasis, and HT may harbor contralateral papillary thyroid carcinoma. …”
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Prognostic Relevance and Function of MSX2 in Colorectal Cancer by Jiancheng Liu, Huaying An, Wei Yuan, Qiang Feng, Lianzhen Chen, Jie Ma

“…Chi-squared test analysis indicated that MSX2 expression was related to tumor size (P=0.04), tumor locus (P=0.025), clinical stage (P<0.001), tumor invasion (P=0.003), lymphatic metastasis (P=0.01), and distant metastasis (P=0.033). …”
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Clinicopathological Features and Increased Expression of Toll-Like Receptor 4 of Gastric Cardia Cancer in a High-Risk Chinese Population by Guangcan Chen, Muming Xu, Jingyao Chen, Liangli Hong, Wenting Lin, Shukun Zhao, Guohong Zhang, Guo Dan, Shuhui Liu

“…Survival was shorter with lymph node metastasis. We found a statistically significant trend for progressive increase of TLR4 expression from normal mucosa to inflammation in GCC. …”
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Hormonal-Receptors-Positive and HER2-Negative Patients with Metastatic Breast Cancer Treated with First-Line Palbociclib and Hormonal Therapy: Impact of First-Cycle Neutropenia and... by Khaled Abd Elaziz Ahmed Elnaghi, Hosam Ali Alghanmi, Shereef Ahmed Elsamany, Fathia Almarzoki, Mohamed Elsafty, Mohammad Jaffal

“…Only the Allred score and having a single site of metastasis had an independent significant relation with PFS. …”
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Uncarboxylated osteocalcin induced miR-143-3p targets SP7 and activates PI3K/Akt signaling in TNBC cells to promote invasion and migration by Qian Du, Jiaojiao Xu, Miao Zhang, Jianhong Yang

“…Patients often have elevated mortality and recurrence rates, along with a pronounced risk of distant metastasis. Our earlier research highlighted the role of uncarboxylated osteocalcin (GluOC) in fueling TNBC cell proliferation and metastasis; however the molecular underpinnings of its impact on cancer invasion and migration remain enigmatic. …”
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Novel Circulating Tumour Cell-Related Risk Model Indicates Prognosis and Immune Infiltration in Lung Adenocarcinoma by Lu Liang, Yueying Liu, Shiyao Jiang, Jingjing Huang, Hua He, Li Shen, Li Cong, Yiqun Jiang

“…LUAD has a low survival rate owing to tumour invasion and metastasis. Circulating tumour cells (CTCs) are precursors of distant metastasis, which are considered to adopt the characteristics of cancer stem cells (CSCs). …”
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EUS-FNA Diagnosis with Core Biopsy of Pancreatic Metastases from Primary Breast Cancer by Samuel Galante Romanini, Juan Pablo Román Serrano, Juliana Silveira Lima de Castro, Isabela Trindade Torres, Alex Ingold, André Lucchiari Borini, Luiz Augusto Sanches Zulske, Maria Bruna Feitosa Matias, Jéssica Said de Marchi, José Andrés Sanchez Pulla, José Celso Ardengh

“…The pancreas as a site of metastasis of other primary tumors is a rare event. …”
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Prognostic Value of Metastatic No.8p LNs in Patients with Gastric Cancer by Dong-Jiao Guo, Kun Yang, Wei-Han Zhang, Xiao-Long Chen, Xin-Zu Chen, Bo Zhang, Zong-Guang Zhou, Jian-Kun Hu

“…Patients with other distant metastasis or not in No.8p+ group had similar cumulative survival rates (24% versus 28%, P=0.914). …”
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High-Fat Mouse Model to Explore the Relationship between Abnormal Lipid Metabolism and Enolase in Pancreatic Cancer by Lin Qin, Kai Sun, Li Shi, Yushan Xu, Rongping Zhang

“…Additional hyperlipidemia promoted pancreatic carcinoma metastasis in the lung in mice injected through the tail vein, which confirmed that hyperlipidemia accelerated the process of EMT by increasing the expression of ENO1, ENO2, and ENO3, therefore promoting the pancreatic cancer cell metastasis.…”
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Progression of an Invasive ACTH Pituitary Macroadenoma with Cushing’s Disease to Pituitary Carcinoma by Clarissa Groberio Borba, Rafael Loch Batista, Nina Rosa de Castro Musolino, Vanielle Carvalho Machado, Ana Elisa Evangelista Alcantara, Gilberto Ochman da Silva, Valter Angelo Sperling Cescato, Malebranche Berardo Carneiro da Cunha Neto

“…The difficulty of defining markers for the diagnosis of carcinoma, before metastasis diagnosis, in order to change the management of the disease, is a challenge.…”
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