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701
Developmental Pathways Pervade Stem Cell Responses to Evolving Extracellular Matrices of 3D Bioprinted Microenvironments
Published 2018-01-01“…To this end, human mesenchymal stem cells (hMSCs) were cultured in 3D bioprinted prisms created from ECM proteins and associated controls. …”
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702
Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering
Published 2016-01-01“…The current study describes the in vitro behavior of human adipose-derived mesenchymal stem cells (hADSCs) encapsulated within calcium/cobalt (Ca/Co) alginate beads. …”
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703
The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview
Published 2022-01-01“…Postnatal teeth, wisdom teeth, and exfoliated deciduous teeth can be harvested for dental stem cell (DSC) researches. These mesenchymal stem cells (MSCs) can differentiate and also consider as promising candidates for dental and oral regeneration. …”
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704
Monitoring Steady Flow Effects on Cell Distribution in Engineered Valve Tissues by Magnetic Resonance Imaging
Published 2013-10-01“…We labeled human vascular smooth muscle (SMCs), endothelial (ECs), and bone marrow–derived mesenchymal stem cells (BMSCs) with superparamagnetic iron oxide (SPIO) microparticles and visualized them using magnetic resonance imaging (MRI) under steady flow. …”
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705
The Interaction between Bmal1 and Per2 in Mouse BMSC Osteogenic Differentiation
Published 2018-01-01“…In this study, we inhibited the expression of Bmal1 in bone marrow-derived mesenchymal stem cells (BMSCs) using a lentiviral vector harboring RNAi sequences, which increased the osteogenic differentiation capability of BMSCs. …”
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706
Recent Developments of Functional Scaffolds for Craniomaxillofacial Bone Tissue Engineering Applications
Published 2013-01-01“…In bone tissue engineering, the scaffolds are fundamental, elemental and mesenchymal stem cells/osteoprogenitor cells and bioactive factors. …”
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707
Nicotinamide Adenine Dinucleotide Phosphate Oxidases and Metabolic Dysfunction-Associated Steatotic Liver Disease
Published 2025-01-01“…NOX acts both in hepatocytes and in non-parenchymal hepatic cells, contributing to hepatocyte lipotoxicity, impaired hepatic microcirculation, hepatic stellate, and mesenchymal stem cells activation and proliferation. This review aims to summarize the current knowledge on the involvement of oxidative stress in the MASLD–MASH transition, focusing on the role of NOX isoforms, and to suggest targeting NOX as a therapeutic approach in MASLD.…”
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708
Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation
Published 2018-01-01“…In this review, we describe the most significant advances in the understanding of autophagy regulation in hematopoietic and mesenchymal stem cells, as well as in induced pluripotent stem cells. …”
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709
Articular Cartilage Repair Using Marrow Stimulation Augmented with a Viable Chondral Allograft: 9-Month Postoperative Histological Evaluation
Published 2015-01-01“…Therefore, host mesenchymal stem cells that infiltrate the graft from the underlying bone marrow following marrow stimulation are provided with the optimal microenvironment to undergo chondrogenesis. …”
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710
Comparative Effects of Umbilical Cord- and Menstrual Blood-Derived MSCs in Repairing Acute Lung Injury
Published 2018-01-01“…Mesenchymal stem cells (MSCs) can effectively relieve acute lung injury (ALI) in several in vivo models. …”
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711
17β-estradiol promotes osteogenic differentiation of BMSCs by regulating mitophagy through ARC
Published 2025-01-01“…Abstract The study aims to elucidate the mechanism through which 17β-estradiol facilitates osteogenic differentiation in bone marrow mesenchymal stem cells (BMSCs). In our study, lentiviral transfection was employed to establish apoptosis repressor with caspase recruitment domain (ARC) knockdown or overexpression in BMSCs. …”
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712
Pediatric Granular Cell Tumor of the Breast: A Case Report and Review of the Literature
Published 2015-01-01“…Granular cell tumors arise from neurogenic mesenchymal stem cells and can occur anywhere throughout the body. …”
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713
Current Status of Human Adipose–Derived Stem Cells: Differentiation into Hepatocyte-Like Cells
Published 2011-01-01“…Recent in vitro studies have demonstrated that mesenchymal stem cells (MSCs) from various sources, including human bone marrow, adipose tissue, and umbilical cord, can be differentiated into hepatocyte-like cells when appropriate conditions are used. …”
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714
Adipose Tissue-Derived Stem Cells Alleviate Cold Allodynia in a Rat Spinal Nerve Ligation Model of Neuropathic Pain
Published 2020-01-01“…Adipose tissue-derived stem cells (ASCs) are multipotent mesenchymal stem cells with potent immunosuppressive properties, and their use as novel cell-based therapeutics have been proposed in many immune diseases. …”
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715
Clinical studies with drugs and biologics aimed at slowing or reversing normal aging processes—emerging results and future perspectives
Published 2024-04-01“…Five families of investigational products are in clinical investigation to slow or reverse normal aging processes [longevity candidates, mesenchymal stem cells, senolytics drugs, sirtuin activators, and nicotinamide adenine dinucleotide (NAD)+ precursors]. …”
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716
An Overview of the Safety, Efficiency, and Signal Pathways of Stem Cell Therapy for Systemic Lupus Erythematosus
Published 2021-01-01“…Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organs and tissues. Mesenchymal stem cells (MSCs) are considered a good source for autoimmune disease and hematological disease therapy. …”
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717
Role of Extracellular Vesicles in Placental Inflammation and Local Immune Balance
Published 2021-01-01“…Various types of cells, such as trophoblasts, endothelial cells, immune cells, mesenchymal stem cells (MSCs), and adipocytes, mediate cell-to-cell interactions through soluble factors to maintain normal placental development. …”
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718
MiRNA-223-5p inhibits hypoxia-induced apoptosis of BMSCs and promotes repair in Legg-Calvé-Perthes disease by targeting CHAC2 and activating the Wnt/β-catenin signaling pathway.
Published 2025-01-01“…This study investigates the role of miRNA-223-5p in regulating hypoxia-induced apoptosis and enhancing osteogenesis in bone marrow mesenchymal stem cells (BMSCs). Utilizing a juvenile New Zealand white rabbit model of LCPD established through femoral neck ligation, we transfected BMSCs with miR-223-5p mimics, inhibitors, and controls, followed by hypoxic exposure. …”
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719
Photobiomodulation: An Effective Approach to Enhance Proliferation and Differentiation of Adipose-Derived Stem Cells into Osteoblasts
Published 2021-01-01“…In osteoporosis, bone mesenchymal stem cells (MSCs) have reduced cellular function. …”
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720
3D Bioprinting Strategies for Melatonin‐Loaded Polymers in Bone Tissue Engineering
Published 2025-01-01“…Polymer‐based biomaterials are mostly used for the controlled release of various drugs, therapeutic agents, mesenchymal stem cells, ions, and growth factors. Polymers are now among the most preferable materials for 3D bioprinting. …”
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