Effectiveness of a specialist palliative home care nurse–patient consultation followed by an interprofessional telephone case conference compared with usual care among patients wit... by Judith Dams, Hans-Helmut König, Tim Friede, Nils Schneider, Stephanie Stiel, Martin Scherer, Silke Böttcher, Gabriella Marx, Ingmar Schäfer, Nadine Janis Pohontsch, Hendrik van den Bussche, Friedemann Nauck, Michael Freitag, Eva Hummers, Tina Mallon, Franziska Schade, Manuel Zimansky, Thomas Asendorf, Christiane A Mueller

“…The concept of KOPAL could serve as a blueprint for other regions and meet the challenges of geographical equity in end-of-life care.Trial registration number DRKS00017795; German Clinical Trials Register.…”
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Humanizing processes after harm part 1: patient safety incident investigations, litigation and the experiences of those affected by Lauren Ramsey, Laura Sheard, Justin Waring, Siobhan McHugh, Ruth Simms-Ellis, Ruth Simms-Ellis, Gemma Louch, Katherine Ludwin, Jane K. O’Hara

“…Systemic fear of litigation not only failed to meet the needs of those affected, but also inadvertently led to some pursuing litigation. …”
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Approaches for difficult-to-induce-seizures electroconvulsive therapy cases (DEC): a Japanese expert consensus by Yoshiteru Takekita, Taro Suwa, Kazuyuki Yasuda, Hirotsugu Kawashima, Wataru Omori, Naoki Kurimoto, Takashi Tsuboi, Takamasa Noda, Nobuatsu Aoki, Ken Wada, Ken Inada, Minoru Takebayash, Expert Consensus Development Working Group, Electroconvulsive Therapy Committee, Japanese Society of General Hospital Psychiatry

“…Our results suggest that while some strategies are applicable across all conditions, others should be tailored to meet the specific needs of patients. These recommendations should be further evaluated in future clinical studies.…”
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Optimizing vaccine uptake in sub-Saharan Africa: a collaborative COVID-19 vaccination campaign in Madagascar using an adaptive approach by Viola Pavoncello, Irina Kislaya, Diavolana Koecher Andrianarimanana, Valentina Marchese, Rivo Rakotomalala, Tahinamandranto Rasamoelina, Simon Veilleux, Ariane Guth, Alexina Olivasoa Tsiky Zafinimampera, Sonya Ratefiarisoa, Olivette Totofotsy, Cheick Oumar Doumbia, Rivomalala Rakotonavalona, Holinirina Ramananjanahary, Zely Arivelo Randriamanantany, Jürgen May, Rivo Andry Rakotoarivelo, Dewi Ismajani Puradiredja, Daniela Fusco

“…Methods Guided by the Dynamic Sustainability Framework (DSF), the VC implementation was regularly reviewed through multi-sectoral stakeholder feedback, key informant interviews, problem-solving meetings, and weekly monitoring of outcome indicators to identify and apply key adaptations. …”
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Bi-level data-driven enterprise-wide optimization with mixed-integer nonlinear scheduling problems by Hasan Nikkhah, Zahir Aghayev, Amir Shahbazi, Vassilis M. Charitopoulos, Styliani Avraamidou, Burcu Beykal

“…Overall, this study demonstrates DOMINO’s ability to optimize production targets, meet market demands, and address large-scale EWO problems.…”
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Topical chlorhexidine 0.2% versus topical natamycin 5% for fungal keratitis in Nepal: rationale and design of a randomised controlled non-inferiority trial by Victor Hu, David Macleod, Helen Anne Weiss, Matthew J Burton, Simon Arunga, Astrid Leck, Sanjay Kumar Singh, Jeremy John Hoffman, Reena Yadav, Sandip Das Sanyam, Pankaj Chaudhary, Abhishek Roshan, Einoti Matayan

“…The results will be presented at local and international meetings and submitted to peer-reviewed journals for publication.Trial registration number ISRCTN14332621; pre-results.…”
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Efficacy of an intervention to increase therapeutic adherence in patients with secondary prevention for cardiovascular disease: a study protocol for a randomized controlled trial by Francisco Manuel Lidón-Muñoz, José Antonio Quesada, José Antonio Quesada, José Antonio Quesada, Vicente Francisco Gil-Guillén, Vicente Francisco Gil-Guillén, Vicente Francisco Gil-Guillén, Domingo Orozco-Beltrán, Domingo Orozco-Beltrán, Domingo Orozco-Beltrán

“…Furthermore, non-adherence is more pronounced in primary care.ObjectiveBased on our hypothesis that in patients undergoing cardiovascular secondary prevention, an intervention grounded in the application of the Chronic Care Model improves adherence to the three preventive drugs, this study aims to evaluate the efficacy of a health education intervention, which implements this model, to increase adherence in patients with cardiovascular disease.MethodsAn open-label randomized controlled trial will be conducted, selecting patients who meet inclusion criteria through consecutive non-probability sampling. …”
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Real-Life State of Anti-Hepatitis B Virus Drug Choice in Child-Bearing Age Male Patients and Effect on Fertility and Fetal Safety by Zhao X. Hu, Yi N. Ye, Wei G. Wu, Xu J. Liang, Qi W. Wu, Ao Zhang, Xing R. Zheng, Zhi L. Gao, Liang Peng, Chan Xie

“…Reasons for not receiving antivirals in 150 patients were “did not meet criteria for antiviral therapy,” fertility, and financial. …”
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Evaluation of the feasibility, acceptability, and impact of Group Antenatal Care at the health post level on continuation in antenatal care and facility based delivery in Ethiopia... by Reena Sethi, Rediet Fasil, Walelegn W. Yallew, Della Berhanu, Yenealem Woldemariam, Gayane Yenokyan, Alemayehu Worku, Dedefo Teshite, Konjit Wolde, Anne Hyre, Stephanie Suhowatsky, Lisa Noguchi

“…Each health post will form one cohort and conduct six monthly G-ANC meetings on a fixed day/time. The study will use quantitative and qualitative data collection approaches. …”
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‘I no longer worry about money for transport to the health centre’ - economic empowerment of caregivers of children living with HIV through Village Savings and Loan Associations: e... by Joseph Rujumba, Carmen Roebersen, Susan Namara, Richard Ochen, Sharon Eva Ahumuza, Allen Tushabe, Mathias Akugizibwe, David Bitira, Innocent Mwesigye, Stella Kentusi, Henry Zakumumpa, Japheth Kwiringira, Merian Natukwatsa Musinguzi

“…Members developed lasting friendships and networks of support which helped them to meet the material and psychological needs of children. …”
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Deflection of screen surface and spatial deformation law of screen apertures during 1 mm elastic screening by Haishen JIANG, Ran YANG, Runyu LIU, Shijie YU, Peng GUO, Miao PAN, Long HUANG, Chenlong DUAN

“…As the external moisture content of the material increased, the high vibration intensity of the elastic screen surface promoted the depolymerization of agglomerated fine-grained particles, strengthening the looseness and permeability of material and its screening performance was significantly better than that of the rigid screen surface, which could meet the technical needs of 1 mm dry screening.…”
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Data-Driven Decision Support Tool Co-Development with a Primary Health Care Practice Based Learning Network [version 2; peer review: 2 approved] by Daniel Lizotte, Eric Sutherland, Paulino Lucamba, Sandra Fitzpatrick, Kelly Angevaare, Sara Bhatti, Jennifer Rayner, Jacqueline Kueper

“…As discussions deepened around clinical use cases associated with example prediction task set ups, the target problem evolved towards supporting the upstream task of organizational planning and advocacy for adequate mental health care service capacity to meet incoming needs. Conclusions This case study contributes towards a tool to support diabetes and mental health care, as well as lays groundwork for future CHC EHR-based decision support tool initiatives. …”
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Diagnosis and management of type 2 diabetes mellitus in patients with ischaemic heart disease and acute coronary syndromes - a review of evidence and recommendations by Muhammad Usman Shah, Muhammad Usman Shah, Alun Roebuck, Bala Srinivasan, Joanna Kate Ward, Paul Edward Squires, Claire Elizabeth Hills, Kelvin Lee, Kelvin Lee

“…However, a significant proportion of individuals who meet the criteria for the diagnosis of diabetes remain undiagnosed, representing missed opportunities for early intervention. …”
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Micronutrient dose response (MiNDR) study among women of reproductive age and pregnant women in rural Bangladesh: study protocol for double-blind, randomised, controlled trials by Tahmeed Ahmed, Hasmot Ali, Michael Rosenblum, Daniel J Erchick, Towfida Jahan Siddiqua, Rezwanul Haque, Parul Christian, Sarah Baker, Eleonor Zavala, Kerry J Schulze, SM Tafsir Hasan, Khalid Bin Ahsan, Sulagna Bandyopadhyay, Hasan Mahmud Sujan, Md. Hafizur Rahman, Katherine K Stephenson, Ximing Ge, Ethan K Gough, Brooke Langevin, Lee Shu Fune Wu, Brian Dyer, Anjan Kumar Roy, Mohammad Jubair, Amena Al Nishan, Mathangi Gopalakrishnan, Klaus Kraemer

“…Findings will be disseminated in peer-reviewed papers and in-country meetings.Trial registration number NCT06081114Cite Now…”
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Refinement of a meaning-centered counseling program for Chinese patients with advanced cancer: integrating cultural adaptation and implementation science approaches by Florence Lui, Qingyi Zhang, George Chengxi Bao, Bharat Narang, Ruo Yan Chen, Yunshan Niu, Jennifer Leng, William Breitbart

“…Conclusion Recommendations for next steps include increasing the MCP-Ch protocol’s flexibility and adaptability to allow interventionists to flexibly tailor MCP-Ch material to meet patients’ individual needs, simplifying content to improve comprehension and acceptability, providing additional training to Chinese-serving providers to increase adoption and sustainability, and considering interpreter-assisted delivery to increase access. …”
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First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale by Ivan Tsers, Ekaterina Marenina, Azat Meshcherov, Olga Petrova, Olga Gogoleva, Alexander Tkachenko, Natalia Gogoleva, Yuri Gogolev, Evgenii Potapenko, Olga Muraeva, Mira Ponomareva, Viktor Korzun, Vladimir Gorshkov

“…M. nivale gene products that best meet the criteria for virulence factors have been identified. …”
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Robotic-assisted surgery and kinematic alignment in total knee arthroplasty (RASKAL study): a protocol of a national registry-nested, multicentre, 2×2 factorial randomised trial as... by Ian A Harris, Samuel J MacDessi, Aziz Bhimani, Darren B Chen, Ian Harris, Michelle Lorimer, David Parker, Tamara Hooper, Richard Boyle, Jonathan Mulford, Daniel Franks, Gregory C Wernecke, Durga Bastiras, Emma Heath, Anthony Leong, Brett Fristch, David Penn, George Kirsh, John Limbers, Julian Yu, Maurice Guzman, Peter McEwen

“…Results will be submitted for publication in a peer-reviewed journal and presented in national, state and international meetings.Trial registration number ACTRN12621000205831.…”
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Health profile of residents of retirement villages in Auckland, New Zealand: findings from a cross-sectional survey with health assessment by Kathy Peri, Michal Boyd, Martin J Connolly, Joanna B Broad, Dale Bramley, Zhenqiang Wu, Katherine Bloomfield, Joanna Hikaka, Annie Tatton, Cheryl Calvert, Ann-Marie Higgins

“…Healthcare service providers and village operators could cooperate to design and test service initiatives that better meet residents’ needs and offer cost benefits.Trial registration number ACTRN12616000685415.…”
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Solving unknown primary cancer with earlier diagnosis - the SUPER-ED trial: study protocol for a stepped-wedge cluster randomised controlled trial to support earlier diagnosis for... by Anna Ugalde, Richard W. Tothill, Stephen Quinn, Hui-Li Wong, Owen Prall, Catherine Mitchell, Nilmini Wickramasinghe, Clare Fedele, Natalie Richards, Elizabeth Todio, Cindy Bryant, Louisa G. Collins, Sarah McLean, Hyun Soo Ko, Tim Akhurst, Christopher Steer, Bo Gao, Mark Wong, Chloe Georgiou, Narayan Karanth, Anna Kuchel, Louise Nott, Shamsudheen Padinharakam, Mark Shackleton, Ian M. Collins, Madhu Singh, Rachel Wong, Zee Wan Wong, Alexis Butler, Tharani Sivakumaran, Penelope Schofield, Linda Mileshkin

“…The intervention is a new model of care comprising four key components: standardised diagnostic workup, dedicated cancer care coordinators, virtual multidisciplinary meetings and a website resource for patients, carers and clinicians. …”
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Bayesian network for predicting mandibular third molar extraction difficulty by Tian Meng, Zhiyong Zhang, Xiao Zhang, Chao Zhang

“…Abstract Background This study aimed to establish a model for predicting the difficulty of mandibular third molar extraction based on a Bayesian network to meet following requirements: (1) analyse the interaction of the primary risk factors; (2) output quantitative difficulty-evaluation results based on the patient’s personal situation; and (3) identify key surgical points and propose surgical protocols to decrease complications. …”
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