Quantification and identification of microfibers released from textiles during simulated accelerated washing by João Pinto da Costa, Ana Costa, Andréa Marinho, Alcina Pimenta, Ana Paula Fonte, Ana L. Patrício Silva, António José Fernandes, Florinda M. Costa, Damià Barceló, Lúcia H.M.L.M. Santos, Armando Duarte, Teresa Rocha-Santos

“…Furthermore, experimental results showed that special care and attention should be paid when resorting to automated software-based identification of microplastics in environmental matrices, as this may not be as accurate as previously considered, particularly for increasingly used techniques, such as pyrolysis-gas chromatography/mass spectrometry.…”
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Bioactive extracts from the industrial byproduct of passion fruit promote better glycemic control in an adjuvant treatment with insulin and prevent kidney and heart damage in rats... by Bárbara Cabral, Ony Araújo Galdino, Iago de Souza Gomes, Jovelina Samara Ferreira Alves, José Ivan Marques, Karla Simone Costa de Souza, Rodrigo Moreira da Silva, Bento João Abreu, Norberto Peporine Lopes, Silvana Maria Zucolotto, Adriana Augusto de Rezende

“…Liquid chromatography coupled to triple quadrupole mass spectrometry (LC-QqQ-MS/MS) identified five C-glycosylated flavonoids (vicenin-2, orientin, isoorientin, vitexin, isovitexin) in the extracts. …”
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Spontaneous base flipping helps drive Nsp15’s preferences in double stranded RNA substrates by Zoe M. Wright, Kevin John Butay, Juno M. Krahn, Isha M. Wilson, Scott A. Gabel, Eugene F. DeRose, Israa S. Hissein, Jason G. Williams, Mario J. Borgnia, Meredith N. Frazier, Geoffrey A. Mueller, Robin E. Stanley

“…Through a combination of nuclease assays, 19F NMR spectroscopy, mass spectrometry, and single particle cryo-EM, we determine that Nsp15 acts most efficiently on unpaired Us, particularly those that are already flipped. …”
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Rational Design of Biocompatible Ir(III) Photosensitizer to Overcome Drug‐Resistant Cancer via Oxidative Autophagy Inhibition by Mingyu Park, Jung Seung Nam, Taehyun Kim, Gwangsu Yoon, Seoyoon Kim, Chaiheon Lee, Chae Gyu Lee, Sungjin Park, Kochan S. Bejoymohandas, Jihyeon Yang, Yoon Hee Kwon, Yoo Jin Lee, Jeong Kon Seo, Duyoung Min, Taiho Park, Tae‐Hyuk Kwon

“…These findings are verified in vitro, using mass spectrometry, live cell imaging, and a model SNARE complex. …”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…The toxicity study revealed that the mice’s behavior, body weight, and organ weights (liver and kidneys) were unaffected by Ferula communis leaf extract administration compared to controls. UHPLC–tandem mass spectrometry (MS/MS) analysis of the extract highlights the presence of 11 compounds, the most abundant of which is p-hydroxybenzoic acid, representing 53.65%. …”
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Hybrid peptides inspired by the RWQWRWQWR sequence inhibit cervical cancer cells growth in vitro by Natalia Ardila-Chantré, Claudia Marcela Parra-Giraldo, Yerly Vargas-Casanova, Andrea Carolina Barragán-Cardenas, Ricardo Fierro-Medina, Zuly Jenny Rivera-Monroy, Jhon Erick Rivera-Monroy, Javier Eduardo García-Castañeda

“…Methods: Hybrid peptides and precursors were synthesized by solid-phase peptide synthesis using the Fmoc/tBu strategy, purified via reverse phase (RP)-solid phase extraction, and characterized by RP-high performance liquid chromatography (RP-HPLC) chromatography and mass spectrometry. In vitro cytotoxicity of hybrid peptides in human cervical cancer cells lines HeLa and Ca Ski was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. …”
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New Triterpenoids from the Leaves of <i>Heritiera littoralis</i> and Their Anti-Inflammatory Activity by Chenyang Ren, Xiaoqin Liang, Rui Pi, Jiwen Xin, Bo Yang, Qingfang Zheng, Yanqin Li, Jun Li, Yanjun Zhang

“…Their structures were identified by spectroscopic analysis, including 1D and 2D nuclear magnetic resonance (NMR), high-resolution electrospray ionization mass spectrometry (HRESIMS), and by comparison with the literature. …”
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The Diagnostic Value of Bile Acids and Amino Acids in Differentiating Acute Coronary Syndromes by Yu Q, Zhao F, Wang S, Jia X, Shen S, Zhao X, Li Y, Song J, Sun M, Liu X, Liu Z

“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) measured 15 bile acids and 19 amino acids. …”
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Microbes and metabolites of a plant-parasite interaction: Deciphering the ecology of Tetrastigma host choice in the world’s largest parasitic flower, Rafflesia by Jeanmaire Molina, Roche C. de Guzman, Rinat Abzalimov, Wenkai Huang, Anusha Guruprasad, Ronniel Pedales, Adhityo Wicaksono, Destiny Davis, John Rey Callado, Hans Bänziger, Piyakaset Suksathan, William Eaton, Pride Yin, Marco Bürger, Mick Erickson, Stephen Jones, James Adams, Susan Pell

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GAMG alleviates liver fibrosis through inducing ferroptosis in inflammatory macrophages via the IRF1/SLC7A11 signaling pathway by Qing Pang, Shuai Zhou, Yong Wang, Hongtao Pan, Zhixin Wang, Xilaing Qin, Chao Zhu, Shilei Chen, Huichun Liu, Xiaosi Hu, Hao Jin

“…IRF1 was significantly increased while ferroptosis related SLC7A11 was significantly down-regulated in GAMG treated inflammatory macrophages. Mass spectrometry metabolomics analysis showed that GAMG significantly affected metabolites associated with LF. …”
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UBE2T/CDC42/CD276 signaling axis mediates brain metastasis of triple-negative breast cancer via lysosomal autophagy by Lin Li, Rong Fu, Yan Chen, Jin Yao, Xiaobing Jiang, Tao Liang, Jun jun Li, Qian zhi Chen, Liang Liang Shi, Ming Xing Xie, Xin Wei Qiao, Qi Hong Cheng, Min Jie Wang

“…Additionally, multiple experimental approaches were implemented, encompassing western blotting, Co-IP, GST pull-down, flow cytometry, mass spectrometry, immunofluorescence, immunohistochemistry, and qRT-PCR to reveal the molecular mechanism of UBE2T-mediated immune escape and BrM.Results Our results indicate that expressed at elevated levels in breast cancer, UBE2T is negatively linked to patient prognosis, especially in BrM of TNBC. …”
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Temporal changes in plasma and milk lipids in response to an esophageal bolus of rumen-protected fish oil in lactating Holstein dairy cows by J.E. Rico, V. Sáinz de la Maza-Escolà, N.D. Senevirathne, P. Deme, N.J. Haughey, R. Gervais, J.W. McFadden

“…Extracted plasma was analyzed for individual FA and phospholipid concentrations using gas chromatography and mass spectrometry. Separated milk fat was analyzed for individual milk FA using gas–liquid chromatography and a flame-ionization detector. …”
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Seasonal Variations in Chemical Composition and Antibacterial and Antioxidant Activities of <i>Rosmarinus officinalis</i> L. Essential Oil from Southwestern Romania by Ludovic Everard Bejenaru, Adina-Elena Segneanu, Cornelia Bejenaru, Andrei Biţă, Felicia Tuţulescu, Antonia Radu, Maria Viorica Ciocîlteu, George Dan Mogoşanu

“…To analyze the constituents of RoEO, a comprehensive gas chromatography/mass spectrometry (GC/MS) method was employed. The analysis aimed to identify and quantify the various components by comparing their mass spectra with reference spectra from the National Institute of Standards and Technology (NIST) Library 2020. …”
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Assessment of Health Risks from Agricultural Soils Contaminated with Polycyclic Aromatic Hydrocarbons (PAHs) Across Different Land-Use Categories of Bangladesh by Sumaya Sharmin, Qingyue Wang, Md. Rezwanul Islam, Weiqian Wang, Yanyan Wang, Christian Ebere Enyoh, Md. Sohel Rana

“…Soil samples were investigated using gas chromatography–mass spectrometry (GC–MS). The findings revealed that the concentrations of ∑16PAH ranged from 299 to 1928 µg/kg, with the lowest levels observed in research areas and the highest in industrial soils. …”
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AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can... by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

“…To uncover the underlying mechanisms of AGD1, RNA pull-down assay, RIP, co-Immunoprecipitation (co-IP), mass spectrometry (MS), Methylated RNA immunoprecipitation (MeRIP) and single-base elongation and ligation-based qPCR amplification method (SELECT) were performed. …”
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Isolation and characterization of novel peptides from fermented products of Lactobacillus for ulcerative colitis prevention and treatment by Dong He, Wen Zeng, Yi Wang, Yifan Xing, Kang Xiong, Nan Su, Chong Zhang, Yuan Lu, Xinhui Xing

“…Herein, 4 novel peptides are identified from AC-WGAF by membrane ultrafiltration, recycling preparative high-performance liquid chromatography, and matrix-assisted laser desorption–ionization time-of-flight/time-of-flight mass spectrometry, possessing anti-colitis activity via using an in vitro model. …”
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Metal complexes in cells: from design of catalytic antioxidants to imaging metal ions and designing metal-based probes in X-ray fluorescence and IR-imaging, a multidisciplinary col... by Policar, Clotilde, Delsuc, Nicolas, Bertrand, Hélène Charlotte

“…Methods to quantify the SOD-like activity, out of cellular context and in cells, and analysis of the integrity of the metal-based antioxidant in cells (through ion mobility coupled with mass spectrometry) will be described. Strategies to develop peptide-based metal complexes through conjugation of a LMW complex with peptides aimed at targeting specific organelle will be presented. …”
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Impact of Methotrexate and 7‐Hydroxymethotrexate Exposure on Renal Toxicity in Pediatric Non‐Hodgkin Lymphoma by Hao Bing, Yi Ma, Jiamin Xu, Qixian Ling, Yanlong Duan, Libo Zhao

“…Plasma MTX and 7‐OHMTX concentrations were determined using a high‐performance liquid chromatography tandem mass spectrometry (HPLC–MS/MS) method. A nonlinear mixed effect model approach was used to build a joint population pharmacokinetic (PopPK) model. …”
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Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts by Arbi Guetat, Slimen Selmi, Abdelrhman T. Abdelwahab, Marwa A. Abdelfattah, Abd Ealrhman M. Elhaj, Roaa T. Mogharbel, M. J. A. Abualreish, Abdullah F. Alanazi, Karim Hosni, Naceur Mejri, Abdennacer Boulila

“…The identity of phenolic compounds of the hydroethanolic extract of S. deserti was conducted through HPLC-Electrospray Ionization-Mass Spectrometry (LC-ESI-MS) analyses.ResultsOral administration of hydroethanolic extract of S. deserti at 200 and 400 mg/kg for 14 days significantly decreased blood glucose and restored the hepatic and renal function by reducing the levels of ALT, AST, ALP, GGT, LDH, urea and creatinine. …”
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Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice by Chuanbing Wang, Yuxia Tang, Jiajia Tang, Jie Zhang, Siqi Wang, Feiyun Wu, Shouju Wang

“…Assessments included magnetic resonance imaging (MRI), mechanical hyperalgesia tests, and inductively coupled plasma mass spectrometry to measure gadolinium levels. Ribonucleic acid (RNA) sequencing and bioinformatic analyses identified differentially expressed genes (DEGs), with validation by quantitative reverse transcription polymerase chain reaction (qRT-PCR) and western blot (WB). …”
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