Expectorant Effects of <i>Atractylodes japonica</i> Koidz. ex Kitam Root Extracts on Particulate Matter-Induced Pulmonary Injury in Mice by Junho Lee, Sana Mansoor, Jeongjun Lee, Hunsuk Chung, Young-Sam Kwon, Khawaja Muhammad Imran Bashir, Jae-Suk Choi, Sae-Kwang Ku

“…The results revealed that AJ significantly alleviated PM_2.5-induced pulmonary injuries, mucus overproduction, and respiratory acidosis in a dose-dependent manner. Notably, body surface redness was reduced by up to 55% at a concentration of 100 mg/kg compared to the control. …”
Get full text

Evaluation of Antimicrobial and Wound Healing Effects of Gold Nanoparticles Containing Abelmoschus esculentus (L.) Aqueous Extract by Shahla Korani, Khodabakhsh Rashidi, Mona Hamelian, Ali R. Jalalvand, Ahmad Tajehmiri, Mitra Korani, Thozhukat Sathyapalan, Amirhossein Sahebkar

“…The Au NPs showed cell viability in a dose-dependent manner, and this technique was found to be nontoxic. …”
Get full text

A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Phenols, II: The Depletion of <i>Nrf2</i> Augments the Cytotoxic Effect Evoked by Tyr... by Tomoko Nishimaki-Mogami, Shosuke Ito, Kazumasa Wakamatsu, Takumi Akiyama, Norimasa Tamehiro, Norihito Shibata

“…Although B16BL6 melanoma cells showed insufficient sensitivity to the cytotoxicity assay, the siRNA-mediated knockdown of the transcription factor NRF2 (NFE2L2) repressed the expression of cytoprotective factors, thereby augmenting the cytotoxicity of all six leukoderma-inducing phenols tested in a tyrosinase-dependent manner, indicating enhanced sensitivity to <i>o</i>-quinone metabolites. …”
Get full text

Unveiling cellular changes in leukaemia cell lines after cannabidiol treatment through lipidomics by David Chamoso-Sanchez, Martina Panini, Clarissa Caroli, Matilde Marani, Lorenzo Corsi, Francisco J Rupérez, Antonia Garcia, Federica Pellati

“…CBD treatment reduced cell viability and initiated apoptotic and necrotic processes in both cancer cell lines in a time and dose-dependent manner, showing acute myeloid leukaemia (HL-60) cells greater sensitivity than chronic myeloid leukaemia ones (K-562), without differences in the activation of caspases 3/7. …”
Get full text

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD by Jongbok Lee, Hyeonjeong Kang, Branson Chen, Yoosu Na, Ismat Khatri, Fraser Soares, Housheng Hansen He, Arjun D. Law, Tianzhong Pan, Armin Gerbitz, Xiaoyu Zhu, Mark D. Minden, Li Zhang

“…In contrast, DNTs suppressed GvHD-inducing activities of Tconv cells in a CD18-dependent manner by mediating cytotoxicity against proliferative Tconv cells. …”
Get full text

LMF-Net: A Learnable Multimodal Fusion Network for Semantic Segmentation of Remote Sensing Data by Jihao Li, Wenkai Zhang, Weihang Zhang, Ruixue Zhou, Chongyang Li, Boyuan Tong, Xian Sun, Kun Fu

“…It provides key-value pairs with multimodal complementary information in a parameter-free manner and assigns them to self-attention (SA) layers of different modal branches. …”
Get full text

Phenolic Compounds from Water-Ethanol Extracts of Tetrapleura tetraptera Produced in Cameroon, as Potential Protectors against In Vivo CCl4-Induced Liver Injuries by Peter William Kemewele Saague, Bruno Moukette Moukette, Jacques Romain Njimou, Prosper Cabral Nya Biapa, Francine Nzufo Tankeu, Vicky Joseline Ama Moor, Constant Anatole Pieme, Jeanne Yonkeu Ngogang

“…In rats treated with the extract of T. tetraptera, in a dose-dependent manner, the levels of hepatotoxicity markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) significantly increased while the enzyme activities of superoxide dismutase (SOD), catalase (CAT), and the level of reduced glutathione (GHS) significantly increased compared to the control group. …”
Get full text

Multi-Task Learning for Alzheimer’s Disease Diagnosis and Mini-Mental State Examination Score Prediction by Jin Liu, Xu Tian, Hanhe Lin, Hong-Dong Li, Yi Pan

“…Therefore, it can be used as a reference for the clinical diagnosis of Alzheimer’s disease, and can also help doctors and patients track disease progression in a timely manner.…”
Get full text

Associations between environmental glyphosate exposure and glucose homeostasis indices in US general adults: a national population-based cross-sectional study by Xiaobing Feng, Min Wang, Yuji Wang, Ruyi Liang, Chunxiang Yan

“…Urinary glyphosate demonstrated a statistically significant positive association with FPG and HbA1c in a linear positive dose–response manner, while showing a linear negative association with HOMA2-β. …”
Get full text

Anti-Tumor Effect of Rutin on Human Neuroblastoma Cell Lines through Inducing G2/M Cell Cycle Arrest and Promoting Apoptosis by Hongyan Chen, Qing Miao, Miao Geng, Jing Liu, Yazhuo Hu, Lei Tian, Jingkun Pan, Yi Yang

“…The cell cycle arrest and apoptosis in a dose-dependent manner was measured by flow cytometric and fluorescent microscopy analyses. …”
Get full text

Recovery of Iodine in the Gaseous Phase Using the Silicone Hollow Fiber Membrane Module by Yoshio Yamabe, Naotake Takahashi, Jun Sawai, Tamotsu Minami, Mikio Kikuchi, Toshimitsu Ishii

“…In the SFMM, iodine gas and the recovery solution (sodium sulfite and sodium carbonate at a concentration of 10 mM each) were flowed outside and inside the silicone hollow fiber, respectively, in a co-current-flow manner. At an iodine gas flow rate of 0.2 L/min (8.4 × 10⁻³ mmol-I₂/L), the capture efficiency of iodine into the SFMM was approximately 100% for all five SFMMs. …”
Get full text

Mebendazole Exerts Anticancer Activity in Ovarian Cancer Cell Lines via Novel Girdin-Mediated AKT/IKKα/β/NF-κB Signaling Axis by Rahul Gupta, Dipanjan Roy, Arijit Ghosh, Yasmin Begum, Dipanjan Ghosh, Snehasikta Swarnakar

“…MBZ inhibited OVCAR3 and OAW42 cell proliferation in a dose- and time-dependent manner. Additionally, MBZ significantly impedes migration, spheroid invasion, colony formation, and stemness. …”
Get full text

Understanding Ozone Formation and Carbonyl Contributions in the Seoul Metropolitan Area by Seung-Ha Lee, Ji-Seon Lee, Hyung-Min Lee, Hyeong-Ahn Kwon, Caroline R. Nowlan, Gonzalo González Abad, Rokjin J. Park, Ji-Hoon Park, Soyoung Kang, Hye-Jung Shin, Dai-Gon Kim, Jung-Min Park

“…Since both regions are changing toward the transition regime, it is important to manage the NOx and VOC concentrations in a balanced manner. We calculated the ozone formation potential (OFP) of each VOC species using Maximum Incremental Reactivity (MIR). …”
Get full text

Chemical Constituents and Combined Larvicidal Effects of Selected Essential Oils against Anopheles cracens (Diptera: Culicidae) by Jitrawadee Intirach, Anuluck Junkum, Benjawan Tuetun, Wej Choochote, Udom Chaithong, Atchariya Jitpakdi, Doungrat Riyong, Daruna Champakaew, Benjawan Pitasawat

“…For larvicidal bioassay, all five essential oils exerted promising efficacy in a dose-dependent manner and different performances on A. cracens after 24 hours of exposure. …”
Get full text

Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu by Sathish Sivaprakasam, Pramodh K. Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy

“…SLC5A8 is a high-affinity transporter in the apical membrane of colonic epithelium which mediates the entry of SCFAs from the lumen into cells in Na+-coupled manner. Due to the unique transport kinetics, the function of the transporter becomes important only under conditions of low dietary fiber intake. …”
Get full text

Quality of bread rolls fortified with date fruit pomace: Structure, proximate composition, staling, and sensory evaluation by Alaa Almoumen, Huda Mohamed, Bhawna Sobti, Mutamed Ayyash, Rabih Kamleh, Ali H. Al-Marzouqi, Afaf Kamal-Eldin

“…Flour fortification with sugar-free pomace (0, 5, 10, 15, and 20 %, w/w) led to bread having darker crust and crumbs in a concentration-dependent manner (P < 0.05). Increasing the pomace concentration levels also led to dense crumb structure, especially at the 20 % level. …”
Get full text

Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival by Linda Kachuri, Geno A. Guerra, Taishi Nakase, George A. Wendt, Helen M. Hansen, Annette M. Molinaro, Paige Bracci, Lucie McCoy, Terri Rice, John K. Wiencke, Jeanette E. Eckel-Passow, Robert B. Jenkins, Margaret Wrensch, Stephen S. Francis

“…Polygenic scores for blood cell traits are also differentially associated with 17 tumor immune microenvironment features in a subtype-specific manner, including signatures related to interferon signaling, PD-1 expression, and T-cell/Cytotoxic responses. …”
Get full text

International Society of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids by Ralf Jäger, Jeffery L. Heileson, Sidney Abou Sawan, Broderick L. Dickerson, Megan Leonard, Richard B. Kreider, Chad M. Kerksick, Stephen M. Cornish, Darren G. Candow, Dean M. Cordingley, Scott C. Forbes, Grant M. Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I. Campbell, Shawn M. Arent, Jeffrey R. Stout, Douglas S. Kalman, Jose Antonio

“…The following conclusions represent the official position of the ISSN: Athletes may be at a higher risk for ω-3 PUFA insufficiency.Diets rich in ω-3 PUFA, including supplements, are effective strategies for increasing ω-3 PUFA levels.ω-3 PUFA supplementation, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been shown to enhance endurance capacity and cardiovascular function during aerobic-type exercise.ω-3 PUFA supplementation may not confer a muscle hypertrophic benefit in young adults.ω-3 PUFA supplementation in combination with resistance training may improve strength in a dose- and duration-dependent manner.ω-3 PUFA supplementation may decrease subjective measures of muscle soreness following intense exercise.ω-3 PUFA supplementation can positively affect various immune cell responses in athletic populations.Prophylactic ω-3 PUFA supplementation may offer neuroprotective benefits in athletes exposed to repeated head impacts.ω-3 PUFA supplementation is associated with improved sleep quality.ω-3 PUFA are classified as prebiotics; however, studies on the gut microbiome and gut health in athletes are currently lacking.…”
Get full text

ThermalGS: Dynamic 3D Thermal Reconstruction with Gaussian Splatting by Yuxiang Liu, Xi Chen, Shen Yan, Zeyu Cui, Huaxin Xiao, Yu Liu, Maojun Zhang

“…Thermal infrared (TIR) images capture temperature in a non-invasive manner, making them valuable for generating 3D models that reflect the spatial distribution of thermal properties within a scene. …”
Get full text

Synthesis of Amino Acid Schiff Base Nickel (II) Complexes as Potential Anticancer Drugs In Vitro by Yang Li, Jianfang Dong, Peiran Zhao, Ping Hu, Dawei Yang, Lei Gao, Lianzhi Li

“…Antitumor mechanism studies showed that complex 2 can increase the autophagy, reactive oxygen species (ROS) levels, and decrease the mitochondrial membrane potential remarkably in a dose-dependent manner in the Eca-109 cells. Complex 2 can cause cell cycle arrest in the G2/M phase. …”
Get full text