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Comparative Analysis of the Therapeutic Effects of MSCs From Umbilical Cord, Bone Marrow, and Adipose Tissue and Investigating the Impact of Oxidized RNA on Radiation-Induced Lung...
Published 2024-01-01“…Additionally, MSCs effectively reduce the accumulation of oxidized RNA in RILI, thereby, presenting a unique avenue for investigating the underlying mechanism of MSC-based treatment for RILI.…”
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Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems
Published 2019-01-01“…In our study, we show that a three-dimensional (3D) culture method is effective to induce MSC spheroid formation, to maintain the multipotency and to improve the paracrine activity of a specific population of human amnion-derived MSCs (hAMSCs). …”
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The Case for Brutalist Honesty in Medical Education
Published 2025-02-01“…D Thomas Markle Department of Family and Community Medicine, School of Medicine, University of New Mexico, Albuquerque, NM, USACorrespondence: D Thomas Markle, Department of Family & Community Medicine, UNM School of Medicine, MSC08 4720, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA, Email dtmarkle@salud.unm.eduIntroduction: The assumption of a prioi trust between students and institutions of medical education is anachronistic and promotes both unnecessary student anxiety and the adoption of hidden curriculums to offset perceived risk due to a lack of transparency. …”
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Effect of In Vitro Exposure of Corticosteroid Drugs, Conventionally Used in AMD Treatment, on Mesenchymal Stem Cells
Published 2012-01-01“…ARPE-19 seemed to help cells preserve the typical MSC morphology. In conclusion, this in vitro study demonstrated that high doses of corticosteroid drugs have a negative effect on MSCs, reduced in the presence of a conditioned media.…”
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Akin Ogundiran: The Historian and Archaeologist of Yoruba-Atlantic becomes Chancellor Professor at the University of North Carolina at Charlotte
Published 2021-12-01“…We are proud of him, as one of the best students produced by Ife. He earned his M.Sc. in archaeology from the University of Ibadan in 1990. …”
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Optimal Dimensional Synthesis of Ackermann Steering Mechanisms for Three-Axle, Six-Wheeled Vehicles
Published 2025-01-01“…The optimized mechanism, designed using the DE-gr method, was validated through kinematic simulations and steering analyses using MSC-ADAMS v2015 software, further confirming the effectiveness and reliability of the proposed design.…”
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Extracellular Vesicle-Loaded Oncogenic lncRNA NEAT1 from Adipose-Derived Mesenchymal Stem Cells Confers Gemcitabine Resistance in Pancreatic Cancer via miR-491-5p/Snail/SOCS3 Axis
Published 2023-01-01“…It is becoming increasingly evident that key mechanisms of mesenchymal stem cell (MSC) efficacy appear to associate with paracrine activities, and the delivery of cargos through extracellular vesicles (EVs) controls the mechanistic actions of MSCs. …”
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Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells
Published 2025-01-01“…However, intracellular signals regulating MSC migration are still incompletely understood. …”
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hUC-MSCs Attenuate Acute Graft-Versus-Host Disease through Chi3l1 Repression of Th17 Differentiation
Published 2022-01-01“…These novel insights into the mechanisms of hUC-MSC immunoregulation may lead to the consistent production of hUC-MSCs with strong immunosuppressive functions and thus improved clinical utility.…”
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5-Aza联合低浓度HS分阶段诱导人和大鼠BMMSC 向肌细胞分化的研究
Published 2008-01-01“…【结果】 ①5-Aza联合20 mL/L HS诱导人和大鼠BMMSC向肌系 分化效能截然不同:对hBMMSC,无论形态学还是免疫细胞化学及RT-PCR均无明显改变;对SD BMMSC,显示了促肌分 化的作用(刺激后desmin,MyoD,myogenin mRMA表达水平上调,Pax7表达水平下调),但形态学无改变?②高代数的 MSC不利诱导分化.③Pax3和MRF4分子在诱导前后均无表达.【结论】 ①5-Aza联合20 mL/L HS诱导BMMSC向肌细 胞分化结果因品系不同而异?…”
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Endometritis and In Vitro PGE2 Challenge Modify Properties of Cattle Endometrial Mesenchymal Stem Cells and Their Transcriptomic Profile
Published 2017-01-01“…All cells expressed mRNAs for selected MSC markers. Endometrial MSCs were challenged in vitro with PGE2 at concentrations of 0, 1, 3, and 10 μM, and their global transcriptomic profile was studied. …”
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896
Performance Evaluation of Compressive Strength Models for SRP and SRG-Confined Concrete Columns
Published 2024-05-01Get full text
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An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells
Published 2021-01-01“…Potentially, these differences could also be exploited to develop an optimal MSC cell therapeutic product that can be used for bone disorders. …”
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Enhancement of Anti-Inflammatory and Osteogenic Abilities of Mesenchymal Stem Cells via Cell-to-Cell Adhesion to Periodontal Ligament-Derived Fibroblasts
Published 2017-01-01“…In addition, the direct-contact coculture enhanced the expression of MSC markers that play important roles in the self-renewal and maintenance of multipotency of MSCs, which in turn induced the osteogenic ability of the cells. …”
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