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  1. 481

    ATP-Dependent Chromatin Remodeling Complex in the Lineage Specification of Mesenchymal Stem Cells by Wen Du, Daimo Guo, Wei Du

    Published 2020-01-01
    “…Key events, including cell proliferation, lineage commitment, and MSC differentiation, are ensured by precise gene expression regulation. …”
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    Strategies to Enhance Mesenchymal Stem Cell-Based Therapies for Acute Respiratory Distress Syndrome by Jibin Han, Yanmin Li, Yuanyuan Li

    Published 2019-01-01
    “…Accordingly, several strategies have been explored to improve MSC retention in the lung and enhance the innate properties of MSCs in preclinical models of ARDS. …”
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  7. 487
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    Protection of the Peritoneal Membrane by Peritoneal Dialysis Effluent-Derived Mesenchymal Stromal Cells in a Rat Model of Chronic Peritoneal Dialysis by Lan Zhou, Ming Zong, Qiunong Guan, Gerald da Roza, Hao Wang, Hualin Qi, Caigan Du

    Published 2019-01-01
    “…Here, we showed that as compared to naive control, daily IP injection of the Dianeal PD solution for 6 weeks without pMSC treatment significantly reduced UF, which was associated with an increase in both PM thickness and blood vessel, while pMSC treatment prevented the UF loss and reduced PM injury and blood vessels. …”
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  9. 489

    Nephroprotective Effect of Mesenchymal Stem Cell-Based Therapy of Kidney Disease Induced by Toxicants by Shujun Lin, Wenshan Lin, Chunling Liao, Tianbiao Zhou

    Published 2020-01-01
    “…Furthermore, a difference in blood urea nitrogen levels between the MSC treatment group and control group was observed for 2-3, 4-5, 6-8, and ≥28 days. …”
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    β-巯基乙醇和bFGF分别诱导大鼠骨髓基质干细胞 成神经元样细胞的生物学性状

    Published 2010-01-01
    “…【目的】 比较β-巯基乙醇(BME)和bFGF分别诱导大鼠骨髓基质干细胞(MSC)所分化神经元样细胞的生物学性状65377; 【方法】 BME和bFGF分别作用于大鼠的MSC,分别于9 h和5 d后,进行神经元样细胞的细胞计数,然后用免疫荧光进行神经元特异性蛋白NF200的鉴定,RT-PCR的方法分析神经元特异性基因NF的表达;Western blotting对检测神经元特异性蛋白NF200的表达65377;【结果】 BME诱导的细胞在加入药物1 h后形态发生改变,9 h时有突起伸出,胞体变亮; bFGF诱导的细胞在诱导后第3天开始有突起伸出,呈神经元样,第5天突起之间相互连接,第7天胞体死亡;而两种药物所分化的神经元样细胞NF200的免疫荧光均成阳性,但bFGF诱导的神经元样细胞的阳性率要显著高于BME所诱导的神经元样细胞; 在RT-PCR中,bFGF诱导的神经元样细胞神经元特异性基因NF200的表达要高于BME所诱导的细胞; western blotting中,bFGF诱导的神经元样细胞神经元特异性蛋白NF200的表达要高于BME所诱导的细胞65377; 【结论】 bFGF和BME均可诱导MSC分化为神经元样细胞65377;但bFGF所诱导的神经元样细胞在从形态上更接近于神经元,而神经元特异性基因NF200 mRNA及神经元特异性蛋白NF200蛋白的表达,均高于BME所诱导的细胞65377;…”
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  12. 492
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    Genetic Markers Can Predict Chondrogenic Differentiation Potential in Bone Marrow-Derived Mesenchymal Stromal Cells by Masami Kanawa, Akira Igarashi, Katsumi Fujimoto, Yukihito Higashi, Hidemi Kurihara, Masaru Sugiyama, Tania Saskianti, Yukio Kato, Takeshi Kawamoto

    Published 2018-01-01
    “…The expression levels of eight genes before the induction of chondrogenic MSC differentiation were significantly correlated with the GAG levels after induction. …”
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    Munsell Soil Colour Prediction from the Soil and Soil Colour Book Using Patching Method and Deep Learning Techniques by Sadia Sabrin Nodi, Manoranjan Paul, Nathan Robinson, Liang Wang, Sabih ur Rehman, Muhammad Ashad Kabir

    Published 2025-01-01
    “…This study aims to predict Munsell soil colour (MSC) from the Munsell soil colour book (MSCB) by using deep learning techniques on mobile-captured images. …”
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    The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche by Melinda Simon, Bálint Major, Gabriella Vácz, Olga Kuten, István Hornyák, Adél Hinsenkamp, Dorottya Kardos, Marcell Bagó, Domonkos Cseh, Adrienn Sárközi, Denes Horvathy, Stefan Nehrer, Zsombor Lacza

    Published 2018-01-01
    “…We investigated the effects of HAS on monolayer MSC cultures and in their natural niche, in 3D subchondral bone and marrow explants. …”
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  18. 498

    Exercise during pregnancy modulates infant cellular and whole‐body adiposity by Alex Claiborne, Filip Jevtovic, Donghai Zheng, Cody Strom, Breanna Wisseman, Samantha McDonald, Edward Newton, Steven Mouro, James DeVente, Joseph A. Houmard, Nicholas T. Broskey, Linda E. May

    Published 2024-12-01
    “…Exercise decreased infant MSC lipid content (p = 0.01) and body fat percentage (p = 0.009) irrespective of dose. …”
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  19. 499

    Hydrogels empowered mesenchymal stem cells and the derived exosomes for regenerative medicine in age-related musculoskeletal diseases by Lixin Liu, Siwen Chen, Yantao Song, Longwei Cui, Yiman Chen, Jiangli Xia, Yibo Fan, Liqun Yang, Lina Yang

    Published 2025-03-01
    “…Hydrogels, acting as an ideal carrier, can enhance the therapeutic effects and application range of MSCs and Exos derived from MSCs (MSC-Exos). Therefore, this review comprehensively summarizes the application progress of MSCs and MSC-Exos combined with hydrogels in age-related MSK disease research. …”
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