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Proteomic characterization of molecular mechanisms of paraquat-induced lung injury in a mouse model
Published 2025-01-01“…Gene Ontology analyses revealed that the DEPs in the PQ-2d and PQ-7d groups were involved primarily in humoral immunity and coagulation-related reactions, whereas those in the PQ-14d group were implicated primarily in chemotactic and regulatory responses. Kyoto Encyclopedia of Genes and Genomes analyses indicated that complement and coagulation cascades were key pathways in the PQ-2d and PQ-7d groups, whereas xenobiotic metabolism by cytochrome P450 was a key pathway in the PQ-14d group. …”
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542
Validation and the role of PDK4 relevant to ferroptosis in degenerative lumbar disc disease
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis were performed on DEGs. …”
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543
Gender Variations in the Oral Microbiomes of Elderly Patients with Initial Periodontitis
Published 2021-01-01“…The linear discriminant analysis effect size showed that the most representative biomarkers were the genus Haemophilus in males, whereas the dominant bacteria in females were Campylobacter. Kyoto Encyclopedia of Genes and Genomes analysis showed that predicting changes in the female oral microbiota may be related to the immune system and immune system diseases are the main factor in males. …”
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544
Electrocatalytic CO Reduction to Produce Long‐chain Products Through Fischer‐Tropsch Pathway
Published 2025-02-01Get full text
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545
IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis
Published 2022-01-01“…Based on the enrichment results of the “Gene Ontology“(GO) and “Kyoto Encyclopedia of Genes and genomes “(KEGG) as well as documented findings of key genes, we further emphasized the potential of IL1RN and PRRX1 as markers of immune infiltrates in CRC and confirmed our hypothesis by compiling data from the UALCAN, Tumor Immune Estimation Resource, and TISIDB databases for these two genes. …”
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546
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547
Construction of an lncRNA-mediated ceRNA network to investigate the inflammatory regulatory mechanisms of ischemic stroke.
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed that differentially expressed mRNAs (DEmRNAs) were significantly enriched in stroke-related pathways. …”
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548
Cuproptosis related lncRNA signature as a prognostic and therapeutic biomarker in osteosarcoma immunity
Published 2025-01-01“…The ESTIMATE algorithm, Gene Ontology and Kyoto Encyclopaedia of Genes and Genomes were applied to explore the underlying mechanisms in the immune landscape of osteosarcoma. …”
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549
High Expression of UPK3A Promotes the Progression of Gastric Cancer Cells by Inactivating p53 Pathway
Published 2022-01-01“…Silencing of UPK3A inhibited the proliferation, migration, and invasion of gastric cancer cells. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that UPK3A was involved in the p53 signaling pathway. …”
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550
The oncogenic roles of GPR176 in ovarian cancer: a molecular target for aggressiveness and gene therapy
Published 2024-12-01“…STRING and Cytoscape were used to determine the top 10 nodes. Kyoto Encyclopaedia of Genes and Genomes analysis indicated that GPR176-related genes were involved in the ECM structural constituent and organisation and so on. …”
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551
Multiomics Integrated Analysis Identifies SLC24A2 as a Potential Link between Type 2 Diabetes and Cancer
Published 2022-01-01“…Then, overlapped differentially expressed genes (DEGs) between T2D verse control and SLC24A2-high verse SLC24A2-low were extracted and imported into weighted correlation network analysis. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and gene set enrichment analysis were used for functional enrichment analysis of DEGs. …”
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552
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553
Identification of retinol dehydrogenase 10 as a shared biomarker for metabolic dysfunction-associated steatotic liver disease and type 2 diabetes mellitus
Published 2025-01-01“…We also analyzed the enriched pathways of shared genes using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. …”
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554
Application of Blockchain Technology in Carbon Trading Market: A Systematic Review
Published 2025-01-01“…To further strengthen the effectiveness of this mechanism, the United Nations (UN) initiated the Kyoto Protocol in 1997, enabling the trading of carbon emission rights in exchange for financial compensation. …”
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555
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556
Interleukin-1β Accelerates the Onset of Stroke in Stroke-Prone Spontaneously Hypertensive Rats
Published 2012-01-01“…At 4 weeks of age (before stroke onset), the plasma level of IL-1β was significantly higher in SHRSP (153.0±49.7 pg/ml) than in Wistar Kyoto rats (WKY) (7.7±3.4 pg/ml, P<0.001 versus SHRSP) or spontaneously hypertensive rats (SHR) (28.0±9.1 pg/ml, P<0.001 versus SHRSP) (n=6 per strain). …”
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557
Formation mechanisms of ethyl acetate and organic acids in Kluyveromyces marxianus L1-1 in Chinese acid rice soup
Published 2023-01-01“…At least 4231 genes and 2937 proteins were identified and 610 differentially expressed proteins were annotated to 30 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways based on the analysis results of transcriptome and proteome. …”
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558
Angiotensin I converting enzyme (ACE) inhibitory activity and antihypertensive effects of rice peptides
Published 2022-11-01“…With spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) as the research objects, RP disposable gastric and long-term gastric irrigation experiments were carried out and systolic blood pressure (SBP) was measured. …”
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559
Single cell transcriptomics in blood of patients with chronic obstructive pulmonary disease
Published 2025-01-01“…Functional analyses were performed using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses. …”
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560
Identification of markers correlating with mitochondrial function in myocardial infarction by bioinformatics.
Published 2024-01-01“…Differentially expressed genes (DEGs) in the dataset were screened by ClusterGVis, Weighted Gene Co-Expression Network Analysis (WGCNA) and GEO2R, and functional enrichment was performed by Gene Set Enrichment Analysis (GSEA) and Kyoto Encyclopedia of Genomes (KEGG). Then mitochondria-associated DEGs (MitoDEGs) were obtained. …”
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