Case Report of Gastrointestinal Bleeding in an Adult with Chronic Visceral Acid Sphingomyelinase Deficiency by David Cassiman, Louis Libbrecht, Wouter Meersseman, Alexander Wilmer

“…This case highlights an unusual presentation of recurrent variceal bleeding in an adult with cirrhosis and portal hypertension due to chronic visceral ASMD. …”
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Migrated intra-uterine device to infra-umbilical skin: a rare case report by Nigat Amsalu Addis, Yared Alem Sibhat, Yohannis Derbew Molla, Wasihun Nigdu Mengestu, Abebe Sinknew Seid, Michael Argaw Damite, Misganaw Abere Worku

“…Case Presentation We present the case of a 38-years-old Ethiopian woman with unusual migration of IUD to the infra-umbilical skin. …”
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An Interactive Clustering-Based Visualization Tool for Air Quality Data Analysis by Mahsa Ashouri, Frederick Kin Hing Phoa, Chun-Houh Chen, Galit Shmueli

“…The tool clusters the series into four clusters that reveal several phenomena, including an improvement in Taiwan’s air quality since 2017 in all regions, although at varying rates, an increasing pattern of PM2.5 concentration when moving from northern towards southern regions, winter/summer seasonal patterns that are more pronounced in certain types of areas (e.g., industrial), and unusual behavior in the southernmost region. The tool provides cluster-specific quantitative figures, like seasonal variations in PM2.5 concentration in different air quality zones of Taiwan, and identifies, for example, an annual peak in early January and February (maximum value around 120 µg m−3). …”
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Deníky Marie Jany hraběnky Harbuval von Chamaré (1722-1792) by Pavla Janáčková

“…Among the most important points of her interest belonged her relationship with her husband Johann Anton Harbuval von Chamaré who is known for his unusual hobbies (for example searching for treasure under the old castle in Potštejn), relationship with other persons of noble origin and reflection of political events of the 18th century. …”
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A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by Estrogen/Gestagen Therapy by Yoshihide Inayama, Koji Yamanoi, Baku Nakakita, Shimpei Shitanaka, Jumpei Ogura, Tsutomu Ohara, Mie Sakai, Haruka Suzuki, Koji Yasumoto, Ichiro Kishimoto, Yusuke Sagae, Yoshimi Kitawaki, Koh Suginami

“…A high secretion of follicle-stimulating hormone (FSH) in reproductive-aged women is unusual. We report a case of recurrent corpus luteum hemorrhage and subsequent ovarian torsion with markedly elevated FSH levels in a reproductive-aged woman in the absence of functional gonadotroph adenoma (FGA) or premature ovarian failure (POF). …”
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Upper arm deep vein thrombosis in a patient with active lupus by Mahmoud Farouk Kamel Hassanein, Alaa Ebrahim, Stephanie Alcine Joseph, Teresa Jack, Ramprasath Anbazhagan, Miguel Fernández Olivares, Olena Kovalska

“…Even within this condition, thrombotic events are typically seen in the legs, and UEDVT remains an unusual presentation. Here, we present a case of a 36-year-old female of African descent with a recent medical history of small joint arthralgia and vaginal bleeding due to uterine fibroids, for which she was prescribed a short course of prednisolone and norethisterone, respectively. …”
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Spectral Variations across Latitudes on Asteroid (3200) Phaethon by M. Angrisani, E. Palomba, A. Longobardo, E. Rognini, A. Migliorini, E. D’Aversa, G. Pratesi, C. Gisellu, F. Dirri, L. Piazzo, T. Arai

“…We propose that the northern region of Phaethon may be linked to unusual chondrites and naturally heated Y-82162 samples (63–125 μ m and/or chips), while the southern region shows similarities to Ivuna CI chondrites heated to 700°C (0–125 μ m). …”
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L’aqueduc du Gier : étude des ponts-siphons du Garon à Brignais et Chaponost (Rhône) et de Beaunant à Sainte-Foy-lès-Lyon (Métropole de Lyon) by Kilian Blanc, Laurie Danielou

“…They were both built in an unusual way: initially constructed with openings between the piers for either economic or aesthetic reasons, the bridges were subsequently filled in because of the risk of the piles collapsing. …”
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Supra-Acetabular Brown Tumor due to Primary Hyperparathyroidism Associated with Chronic Renal Failure by Rosaria M. Ruggeri, Emanuele Calamoneri, Antonia Russo, Alessandro Sindoni, Baldassarre Mondello, Maurizio Monaco, Michele A. Rosa, Sergio Baldari, Salvatore Benvenga, Alfredo Campennì, Francesco Trimarchi

“…This case is noteworthy because (1) primary hyperparathyroidism was not suspected due to the normocalcemia, likely attributable to the coexistence of chronic renal failure; and (2) it was associated with a brown tumor of unusual location (right supra-acetabular region).…”
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A 7,000 years trajectory of socio-ecosystems in the montane belt of the northern French Alps by Andréa Julien, Andréa Julien, Erwan Messager, Elise Doyen, David Etienne, Laurent Marquer, Charline Giguet-Covex

“…., the socio-ecosystem.DiscussionWhile the agroecosystem trajectory reconstructed on the Plateau des Glières is rather consistent with the altitudinal model of anthropization previously proposed for this region, the vegetation response to the activities is unusual because it shows a long phase of ecosystem stability despite the relatively high human pressure.…”
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Coinfection of Herpes Simplex virus 2 and Mycobacterium chelonae in acute hydrops associated with keratoconus: A case report by Pedro Marques-Couto, Ana Gama-Castro, Teresa Carvalho, Rodrigo Vilares-Morgado, João Pinheiro-Costa, Dolores Pinheiro, Ana Maria Cunha

“…The combination of corneal edema, previous viral infection, and prolonged corticosteroid use likely created a “perfect storm” scenario, predisposing the patient to this unusual coinfection. Our findings highlight the need for heightened awareness of atypical infections in patients with acute hydrops and suggest that such complications may alter corneal barrier function. …”
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Probing the Relationships Between Mandaeans (the Followers of John the Baptist), Early Christians, and Manichaeans by Brikha H. S. Nasoraia

“…‘Gnosticism’ was a block of creative religious activity mostly responding to the early Christian teachings in unusual ways of cosmicizing Jesus, and presenting a challenge to the ancient church fathers in the first-to-third centuries CE. …”
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Flat-band based high-temperature ferromagnetic semiconducting state in the graphitic C4N3 monolayer by Chaoyu He, Yujie Liao, Tao Ouyang, Huimin Zhang, Hongjun Xiang, Jianxin Zhong

“…Interestingly, such a corrugated Pca21 C4N3 monolayer is found to be both piezoelectric and ferroelectric, which makes it an unusual metal-free two-dimensional multiferroic.…”
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Extracorporeal membrane therapy in a case of ruptured abscess on the mitroaortic intervalvular fibrosa associated to multisystem inflammatory syndrome: a case report by Lina P. Montaña-Jimenez, Ana M. Aristizabal, Carlos A. Guzmán-Serrano, Cesar Cely Reyes, Juan Fernando Vélez Moreno, Gastón Castillo

“…However, the rupture of the mitroaortic intervalvular fibrosa kept being unusual, making this case a rare presentation of a COVID-19 complication. …”
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Complex and severe infection in a 67-year-old liver transplant recipient due to Cunninghamella elegans, Bordetella bronchiseptica, and Pneumocystis jirovecii by Muyun Wei, Kangyi Gu, Juanxiu Qin, Xinhua Lu, Junqi Feng, Shaowei Mao, Min Li, Zhilan Li, Changsheng Wang

“…During the treatment process, we also observed rare and unusual neurological side effects: visual and auditory hallucinations, restlessness, and aphasia. …”
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AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic β-solenoid structures for repeat proteins by Olivia S. Pratt, Luc G. Elliott, Margaux Haon, Shahram Mesdaghi, Rebecca M. Price, Adam J. Simpkin, Daniel J. Rigden

“…AF2 frequently folds such sequences into β-solenoids which, while ascribed high confidence, contain unusual and implausible features such as internally stacked and uncompensated charged residues. …”
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Sarcomatous tumor with external iliac vein aneurysm: a rare entity by Tushar Kalekar, Neeha Amit Jhala, Reetika Kapoor, Eshan Chetan Durgi, Karishma Krishnani

“…This case report describes an unusual presentation of thigh soft tissue sarcoma complicated by external iliac venous aneurysm formation, highlighting the importance of early recognition and management of vascular complications in sarcoma patients. …”
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Overlooking the Obvious during the COVID-19 Pandemic: Dyspnoea with Asymmetric Breath Sounds in a Toddler by Heli Salmi, Heini Harve-Rytsälä, Paula Rautiainen, Sari Pyörälä, Johanna Hästbacka

“…Foreign body aspiration—an obvious cause of acute respiratory distress in our patient’s age group—was overlooked by experienced emergency medical care providers and paediatric critical care physicians due to the slightly unusual presentation, incomplete anamnestic information, and a bias to consider COVID-19 in the current exceptional circumstances. …”
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Adult Ileo-Ileo-Caecal Intussusception: Case Report and Literature Review by Sanjeev Singhal, Anu Singhal, Pankaj K. Arora, Rahul Tugnait, Bishwanath Tiwari, Pawan Malik, Ankur Subhash Dhuria, Vineet Varghese, Mriganka Deuri Bharali, Singh Chandrakant, Pushkar, Vishnu Panwar, Amit Ballani, Neeti Gupta, Vijay Kumar Ramteke

“…Unlike paediatric intussusceptions which are usually idiopathic, there is usually a lead point pathology which might be malignant in up to 50% cases. We present an unusual case of adult intussusception which was not diagnosed on any investigation including computerized tomographic (CT) scan and magnetic resonance imaging (MRI). …”
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Hypercalcemia and co-occurring TBX1 mutation in Glycogen Storage Disease Type Ib: case report by Zakaria Kasmi, Imane Ain El Hayat, Zahra Aadam, Abderrahmane Errami, Ibtihal Benhsaien, Jalila EL Bakkouri, Dalal Ben Sabbahia, Meryem Atrassi, Ahmed Aziz Bousfiha, Fatima Ailal

“…A novel aspect of this case involves hypercalcemia as an unusual finding in GSD-Ib and the co-occurrence of a variant in the TBX1 gene, which is not typically associated with the disease but may contribute to the patient’s clinical presentation. …”
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