Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus by Maofei Zhu, Maofei Zhu, Yueming Chu, Yueming Chu, Qiang Yuan, Qiang Yuan, Junfeng Li, Silin Chen, Lin Li, Lin Li, Lin Li

“…The STRING database was employed to conduct protein-protein interaction (PPI) analysis of differentially expressed onco/tumor suppressor genes, the network was further constructed in Cytoscape, and hub genes of the network were obtained through the Cytohubba plugin. …”
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Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE by Metin Yesiltepe, Tao Yin, Marc Tambini, Hanmei Bao, Meixia Pan, Cristina d’Abramo, Luca Giliberto, Xianlin Han, Luciano D’Adamio

“…These rats were crossed with those carrying a humanized App allele to express human Aβ, which is more aggregation-prone than rodent Aβ, enabling the study of human APOE-human Aβ interactions. In this study, we focused on 80-day-old adolescent rats to analyze early changes that may be associated with the later development of LOAD. …”
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Unravelling hybridization in Phytophthora using phylogenomics and genome size estimation by Kris Van Poucke, Annelies Haegeman, Thomas Goedefroit, Fran Focquet, Leen Leus, Marília Horta Jung, Corina Nave, Miguel Angel Redondo, Claude Husson, Kaloyan Kostov, Aneta Lyubenova, Petya Christova, Anne Chandelier, Slavcho Slavov, Arthur de Cock, Peter Bonants, Sabine Werres, Jonàs Oliva Palau, Benoit Marçais, Thomas Jung, Jan Stenlid, Tom Ruttink, Kurt Heungens

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Technology acceptance and use among nursing staff in Latin American hospitals: A mixed methods study by Juan Manuel Aranda, María Elisa Moreno-Fergusson, William Javier Guerrero, Beatriz Sanchez Herrera, María Alejandra Galiano, Maryory Guevara, Ingrid Xiomara Bustos, Francisca Muñóz

“…Nevertheless, the human-computer interaction is a concern in compassionate patient care and nurses' professional well-being. …”
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Optimization of Key Parameters for Coal Seam L-CO₂ Phase Transition Blasting Based on Response Surface Methodology by Xuanping Gong, Xiaoyu Cheng, Cheng Cheng, Quangui Li, Jizhao Xu, Yu Wang

“…A single-factor analysis reveals that the blasting load positively impacts fracture generation, while in situ stress and differential stress have negative effects. The three-factor interaction model shows that as the in situ stress and stress difference increase, their inhibitory effects become stronger, while the enhancement effect of the blasting load continues to grow. …”
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Overflytting av intensivpasienter til sengepost – en kvalitativ studie av intensivsykepleieres og postsykepleieres erfaringer med kommunikasjon og samarbeid by Ingeborg Einarsrud, Marit Hegg Reime

“…ENGLISH ABSTRACT Transfer of Intensive Care Patients to General Medical Wards – A Qualitative Study of intensive Care Nurses’ and Ward Nurses’ Experiences with Communication and Collaboration Background: Intra-hospital handovers require comprehensive planning, coordination and communicative interaction between nurses to ensure continuity in patient care. …”
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Work performance, physiological and hemato-biochemical responses in working buffalo with different load weights by Visoky Paján-Jiménez, Fernando D. Pazmiño-Rodríguez, Patricia Roldán-Santiago, Cristian Larrondo-Cornejo, Anna Dutro-Aceves, Luis A. de la Cruz-Cruz

“…All variables were compared with a mixed model for repeated measures, considering the factors time and load weight and Time x Load weight interactions as fixed effects, with the animal in each group as a random effect. …”
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Genomic insights into genetic diversity and seed coat color change in common bean composite populations by Eva Plestenjak, Eva Plestenjak, Mohamed Neji, Lovro Sinkovič, Vladimir Meglič, Barbara Pipan

“…The identification of key genomic regions and pathways associated with seed pigmentation improves our understanding of the complex genetic interactions underlying this trait. These results provide valuable genomic resources for future breeding efforts aimed at improving seed color and other important traits in common bean.…”
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Speciation of Potentially Carcinogenic Trace Nickel(II) Ion Levels in Human Saliva: A Sequential Metabolomics-Facilitated High-Field ¹H NMR Investigation by Kayleigh Hunwin, Georgina Page, Mark Edgar, Mohammed Bhogadia, Martin Grootveld

“…Removal of the interfering effects arising from the differential biomolecular compositions of the WMSS samples collected from different participants and those from the effects exerted by a first-order interaction effect substantially enhanced the statistical significance of the differences observed between the added Ni(II) levels. …”
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Immunological and autonomic profile of ischemic stroke in lowlands by Nargiza T. Chekeeva, Svetalana G. Shleifer, Bolot B. Kulov, Begimai B. Kadyrova, Asel T. Jusupova, Elena V. Andrianova

“…Among the 8 patients with fatal stroke, the number of significant correlations doubled compared to mild stroke, reaching 59.2%. Conclusion: The interaction between the immune and autonomic systems in IS depends on disease severity. …”
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Efficacy of the internet-based intervention “Cultivating our resilience” (CORE) for improving resilience and coping strategies in university students: A randomized controlled trial... by Rocio Herrero, Marvin Franke, Dennis Görlich, Azucena Garcia-Palacios, Rosa Baños, Corinna Jacobi, Thomas Berger, Michael P. Schaub, Tobias Krieger, David D. Ebert, Cristina Botella

“…Participants were instructed to engage in six interactive modules delivered weekly in a sequential order. …”
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Association of glucose to lymphocyte ratio with the risk of death in patients with atherosclerotic cardiovascular disease by Jinglin Lei, Wentao Duan, Xiaoxi Yao, Zheng Hu, Huihui Fan, Yifan Liu, Wenjian Zhong, Haipeng Li

“…Subgroup analysis revealed a positive association between GLR and CVD mortality across most subgroups, but the correlation between GLR and CVD mortality was weaker compared to its association with all-cause mortality. In addition, an interaction was detected between GLR and age in relation to all-cause mortality. …”
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Learning with Digital Tools vs. Learning Through Digital Tools in Physical Education: Impacts on Student Perceptions by André Klostermann, Till Etterlin

“…Contrary to expectations, LWD consistently exhibited higher PU than LWTD across all measurement points, especially at posttest (LWD: M = 3.84 ± 0.6; LWTD: M = 3.37 ± 0.7). However, this interaction was statistically not significant, F(2, 62) = 1.51, p = .23, ηp² = 0.05. …”
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Association of systemic immune-inflammatory index with in-stent restenosis in patients with and without diabetes mellitus by Xunwei Deng, Xunwei Deng, Xunwei Deng, Qiaoting Deng, Qiaoting Deng, Qiaoting Deng, Qunji Zhang, Qunji Zhang, Qunji Zhang, Jingyuan Hou, Jingyuan Hou, Jingyuan Hou

“…Multivariable logistic regression models were employed to assess the associations between SII and ISR prevalence. Additionally, the interaction test and subgroup analysis were performed to evaluate the robustness of our findings. …”
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The effect of rootstocks on morphological, physiological, and gene expression characters of citrus seedlings grown under drought condition by Nirmala Friyanti Devy, Siti Subandiyah, Sri Widyaningsih, Hardiyanto Hardiyanto, Farida Yulianti, Dita Agisimanto, Agus Sugiyatno, Mutia Dwiastuti

“…Regardless of scion-rootstock interaction, KB enhanced the relative quantity of several genes such as 1-Aminocyclopropane-1-carboxylate (ACC) synthase, Chlase, ethylene receptors (ETR1), osmotin, plasma membrane instrinsic proteins (PIP1), and PIP2 allowing it to respond more effectively to drought stress conditions. …”
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Effet de la fertilisation azotée et de l’irrigation supplémentaire sur la production du blé tendre dans le périmètre du Saïs au Maroc by Khalid DAOUI, Abderrazzak Bendidi, Wafae Sellami, Rachid Dahan, Mohamed Ibriz

“…En outre, l'application d'azote à un taux de 145 kg N ha-1 a entraîné une augmentation significative du rendement en grains, du nombre de grains, du poids du grains et de l'efficience d'utilisation de l'eau de 60%, 25%, 10% et de 59%, respectivement, par rapport à la faible dose d'azote qui est de 20 kg ha-1, au cours de cette campagne agricole caractérisée par une pluviométrie élevée. De plus, l'interaction entre l'irrigation supplémentaire et l'azote a démontré un effet hautement significatif sur toutes les composantes mesurées. …”
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Unveiling GPT-4V's hidden challenges behind high accuracy on USMLE questions: Observational Study by Zhichao Yang, Zonghai Yao, Mahbuba Tasmin, Parth Vashisht, Won Seok Jang, Feiyun Ouyang, Beining Wang, David McManus, Dan Berlowitz, Hong Yu

“…However, significant shortcomings were observed in the quality of explanations when questions were answered incorrectly, particularly in the interpretation of images, which could not be efficiently resolved through expert interaction. These findings reveal hidden flaws in the image interpretation capabilities of GPT-4V, underscoring the need for more comprehensive evaluations beyond multiple-choice questions before integrating GPT-4V into clinical settings.…”
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Sequential use of low-load-blood-flow-restricted vs. high-load resistance training on neuromuscular activation, hypertrophy and neuromuscular performance by Romina Ledergerber, Paul Ritsche, Eric Lichtenstein, Martin Keller

“…No meaningful differences in VA changes were observed between groups or across timepoint, however, the interaction at POST favored more change in BFRT compared to HLT (d=-0.3). …”
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The authority of the printed word in the Lithuanian village of the XIX century by Džiuljeta Maskoliūnienė

“…In general, in the epoch of Enlightenment, the peasant's topic arises (the peasant becomes an object of literary portrayal as well). Interaction with the printed text (a prayer book, hymnal, fiction, calendar, map) turns into a new form of communication. …”
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Evaluation of in-vitro and in-silico antidiabetic potential, glucose metabolism, antioxidant, cytotoxicity and phytochemical content of Ipomoea bolusiana Schinz and Ipomoea crassip... by Garland Kgosi More, Nolitha Nkobole, Charmy Twala, Sechaba Machedi, Tebogo Amos Moswetsa, Ramakwala Christinah Chokwe

“…Furthermore, phytochemical characterization and tentative identification was performed using FTIR, 1HNMR and UHPLCOrbitrap HRMS, FTIR, whilst computational studies were also employed to determine the biochemical interaction, antidiabetic and inhibitory potential of the extracts with the α-amylase enzyme. …”
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