Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data by Zhou J, Jiao S, Huang J, Dai T, Xu Y, Xia D, Feng Z, Chen J, Li Z, Hu L, Meng Q

“…Single-cell RNA sequencing analysis provided insights into the characteristics of distinct cell clusters in OA synovial tissues and their interactions with Hub PCD-DEGs.Results: We identified five Hub PCD-DEGs: TNFAIP3, JUN, PPP1R15A, INHBB, and DDIT4. qRT-PCR analysis confirmed that all five genes were significantly downregulated in OA synovial tissue. …”
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Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric... by Kuan-Yi Wu, Yen-Ju Chen, Shu-Fan Lin, Hong-Ming Hsu

“…Beyond cytoadherence, during host-parasite interactions, TvArf220 influenced both contact-dependent and -independent cytotoxicity, as well as phagocytotic capacity, contributing to the cytopathogenesis of human vaginal epithelial cells. …”
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Evaluating user experience in cultural heritage through virtual reality simulations by Shinnu Jangra, Gurjinder Singh, Archana Mantri

“…VR-Simulator provides participants with an immersive and interactive museum experience using a Mobile-VR headset. …”
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Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats by Hong Yang, Cheng Zhang, Woonghee Kim, Mengnan Shi, Metin Kiliclioglu, Cemil Bayram, Ismail Bolar, Özlem Özdemir Tozlu, Cem Baba, Nursena Yuksel, Serkan Yildirim, Shazia Iqbal, Jihad Sebhaoui, Ahmet Hacımuftuoglu, Matthias Uhlen, Jan Boren, Hasan Turkez, Adil Mardinoglu

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Genome-Wide Comprehensive Identification and In Silico Characterization of Lectin Receptor-Like Kinase Gene Family in Barley (Hordeum vulgare L.) by Fee Faysal Ahmed, Farah Sumaiya Dola, Md Shohel Ul Islam, Fatema Tuz Zohra, Nasrin Akter, Shaikh Mizanur Rahman, Md. Abdur Rauf Sarkar

“…In addition, 46 putative miRNAs were predicted to target 81 HvlecRLK genes and HvlecRLK13 was the most targeted gene by 8 different miRNAs. Protein-protein interaction analysis demonstrated higher functional similarities of 63 HvlecRLKs with 7 Arabidopsis STRING proteins. …”
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High-Pressure Treatment in Combination with Reduced Sodium for Improving the Physicochemical Properties and Sensory Qualities of Pork Gels by Weitong Wang, Jingying Cai, Satomi Tsutsuura, Tadayuki Nishiumi

“…Protein analysis by sodium dodecyl sulfate–polyacrylamide gel electrophoresis showed a reduction in the <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>α</mi></semantics></math></inline-formula>-actinin band with increased pressure, which suggested protein interactions were enhanced. Differential scanning calorimetry analysis indicated that protein denaturation occurred more readily at higher pressures (0.071 J/g at 0.1 MPa, 0.057 J/g at 150 MPa, and 0.039 J/g at 200 MPa). …”
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Call to Action: Lead Pharmacy into the Next Decade by Gregory Zumach, Kerry K Fierke, Gardner Lepp, Bridget McGugan, Marta Brooks, Anthony Olson, Andrew Bartlett, Nilushi Karunaratne, Betty Exintaris

“…This scholarship is connected to the following forms of scholarly works: Call to Action: Lead Pharmacy into the Next Decade: https://doi.org/10.24926/iip.v15i4.6262 Call to Action: Lead Pharmacy into the Next Decade an Interactive Poster: https://doi.org/10.24926/iip.v15i4.6264     References   • Sorensen TD, Traynor AP, Janke KK. …”
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Clinical Study of Repetitive Transcranial Magnetic Stimulation Combined with Social Rehabilitation Training on Children with Attention Deficit Hyperactivity Disorder by JING Xinli, ZHU Min, NIU Yujia

“…The PEERS social rehabilitation training course consisted of 6 parts: communication, information interaction, game initiation, self-initiative, disagreement resolution and social pragmatics, which had 12 classes, 50 minutes per session, once a week, for 12 weeks. …”
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Measurement of Corneal Biomechanical Properties using Corneal Visualisation Scheimpflug Technology and Ocular Response Analyser in Healthy Saudi Female Adults: A Cross-sectional St... by Farah Maqsood, Noura Aldossari, Menwah Al Matrafi, Musarat Amina, Maram M Bawazir

“…Introduction: Corneal biomechanics is a relatively new discipline of research that focuses on the physical and biological interactions in the anterior part of the eye. Corneal biomechanics is influenced by a wide range of variables, including environmental influences, hydration, and hormone changes. …”
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The Role of Human Agency in Global Urban Health by Kai Michael Gensitz, Catherine Woods, Tadhg MacIntyre, Claudio R. Nigg

“…Each SEC and its associated health indicators potentially interact with each other. Human agency acts as the central force within Global Urban Health, linking individual actions to SECs and shaping transformative efforts against global health challenges. …”
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Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study by Myungsung Kim, Seonmi Lee, Sieun Kim, Jeong-in Heo, Sangil Lee, Yu-Bin Shin, Chul-Hyun Cho, Dooyoung Jung

“…MethodsA single-group pre-post study was conducted with university students who interacted with the chatbot for 4 weeks. Measures included loneliness, social anxiety, and mood-related symptoms such as depression, assessed at baseline, week 2, and week 4. …”
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Users’ Perspectives of Direct-to-Consumer Telemedicine Services: Survey Study by Kate Churruca, Darran Foo, Andrew Turner, Emily Crameri, Maree Saba, Samantha Spanos, Matthew Vickers, Jeffrey Braithwaite, Louise A Ellis

“…ObjectiveIn this study, we aimed to examine the perspectives of Australian users accessing DTC telemedicine services, including the reasons for use, perceived benefits, and concerns, in addition to their usage and interaction with traditional general practice services. …”
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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

“…Bidirectional Mendelian randomization analysis, Steiger filtering, colocalization, and phenotype scanning were employed for reverse causal inference detection, further substantiating the Mendelian randomization results. A protein-protein interaction network was also constructed to reveal potential associations between proteins and asthma medications. …”
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Identifying the Antecedents of Employee Perceptions of Human Resource Practices Using Signaling Theory by Aryan Gholipour, Mohammad Abooyee Ardakan, Neda Mohammad Esmaeili, Atiyeh Rasouli

“…The analysis sought to understand how these antecedents interact with and influence employees’ perceptions across different contexts. …”
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Smartphone-Based Telemonitoring for Better Oral Health With Toothbrushes: 6-Month Randomized Controlled Trial by Jaeyeon Kim, Yiseul Choi, Yoolbin Song, Wonse Park

“…ObjectiveThis 6-month prospective randomized controlled trial aimed to compare the clinical effectiveness, defined as improved oral hygiene measured by plaque reduction and halitosis control, of an interactive telemonitoring toothbrush (ITT), an oscillating-rotating power toothbrush (ORT), and a manual toothbrush (MT). …”
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Le temple polygonal de la rue Lecointre à Reims/Durocortorum by Sébastien Péchart, Frédéric Poupon

“…The proximity and chronology of the amphitheater and the abundance of wildlife found within the peribolos ditch, may testify to the organization of venatio in the amphitheater, suggesting strong interactions between the temple and the amphitheater, as is sometimes the case in Gaul between performance and sanctuary spaces. …”
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Development and model test of dynamic loading system in mine goaf site for high-speed railway subgrade by Lianwei REN, Liang LI, Ziqiang WANG, Youfeng ZOU, Zhilin DUN, Shuren WANG

“…This study examines the causes of the triangular separation space under the main key stratum and discusses the transmission path of dynamic load in the overburden rock of the goaf at different loading stages. It analyzes the interaction between the caving fault zone and the bending deformation zone under dynamic load, and reveals the activation mechanism of the foundation in the goafunder a high-speed rail load. …”
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Characterization of dynamic stall of a wind turbine airfoil with a high Reynolds number by H. R. Kim, J. A. Printezis, J. D. Ahrens, J. R. Seume, L. Wein

“…The analysis of the frequency spectra of unsteady pressure confirms the distinct characteristics of the leading-edge vortex street and its interaction with large-scale mid-chord vortices in forming the dynamic-stall vortices (DSVs). …”
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Voacanga africana-artesunate and Voacanga africana-amodiaquine combinations as effective anti-plasmodial agents in mice by Daniel Ampomah Frimpong, Aliu Moomin, Samuel Asare Nkansah, Aaron Opoku Antwi, Abubakar Ibn Sidik, Paa Kofi Tawiah Adu-Gyamfi, Kwesi Boadu Mensah

“…We used an isobologram to determine the combination index (CI) and the nature of the interaction between VA-artesunate or VA-amodiaquine combinations by comparing the CI with Zexp. …”
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The association of visceral and subcutaneous fat areas with phenotypic age in non-elderly adults, mediated by HOMA-IR and HDL-C by Yuanhong Liu, Min Xu, Liqing Wang, Linyun Meng, Mengran Li, Shumin Mu

“…The dose‒response relationship between body fat area and PhenoAgeAccel was determined via restricted cubic spline analysis. Mediation and interaction analyses were further employed to investigate the roles of the HOMA-IR and HDL-C in this association. …”
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