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20641
Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1
Published 2025-03-01“…Furthermore, differentially expressed miRNAs in hDMSCs were analyzed through miRNA sequencing. We evaluated the interaction between hsa-miR-532-3p and KEAP1 using a luciferase reporter assay. …”
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20642
Glasswort as a Strategic Crop in Coastal Wetlands: Intercropping Results with Swiss Chard
Published 2025-01-01“…These were performed to test for possible interaction effects. The results showed that both glasswort and chard can be grown sustainably under slightly saline conditions (ECe range 4–8 dS m<sup>−1</sup>). …”
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20643
Immune infiltration landscape and potential drug-targeted implications for hepatocellular carcinoma with ‘progression/hyper-progression’ recurrence
Published 2025-12-01“…Co-expression and protein interaction analyses were used to identify characteristic genes in ITM closely associated with type III–IV recurrence, which was matched with drug targets for Huaier granules (HG) and lenvatinib. …”
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20644
Phosphorus transitions driven by cyclone biparjoy linked middle east North Africa (MENA) and Indian Thar Desert dust storm pathways in Asia’s largest grassland
Published 2025-02-01“…Ultimately, our research contributes to the broader understanding of global nutrient cycling and land‒air interactions, enabling informed decision-making for the conservation and sustainable management of terrestrial ecosystems.…”
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20645
Alloplasmic recombinant lines (H. vulgare)-T. aestivum with 1RS.1BL translocation: initial genotypes for production of common wheat varieties
Published 2018-08-01“…Since the cytoplasm replacement results in new intergenomic interactions between a nucleus and cytoplasm leading to variability of plant characteristics, alloplasmic lines with restored fertility can be an additional source of biodiversity of cultivated plants. …”
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20646
Transcription factor-dependent regulatory networks of sexual reproduction in Fusarium graminearum
Published 2025-01-01“…Using transcriptomic data across stages of sexual development, we inferred a Bayesian network of these TFs that guided experiments to assess the robustness of gene interactions using a systems biology approach. We discovered that the mating-type locus (MAT genes) initiates a transcriptional cascade, with PNA1 identified as an upstream activator essential for early sexual development and ascospore production. …”
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20647
Tetrazenyl-, Imido-, and Azidoaluminate Derivatives of a Sterically Demanding Bis-Silazide Ligand
Published 2025-01-01“…Attempts to synthesise the azide [{SiN<sup>Dipp</sup>}AlN<sub>3</sub>] by reaction of [{SiN<sup>Dipp</sup>}AlI] with an excess of KN<sub>3</sub> resulted in exclusive formation of the bis(azido)aluminate [{SiN<sup>Dipp</sup>}Al(N<sub>3</sub>)<sub>2</sub>K], which crystallises as an infinite 1-dimensional polymer propagated by μ-(1,3)-N<sub>3</sub> bridging interactions between the potassium cations and azide anions. …”
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20648
Förändringsrummet i fyra dimensioner: Att navigera osäkerhet och möjliggöra transformativt samskapande
Published 2024-12-01“…Based on experiences of interactive research projects, four ways, or “dimensions”, have emerged as particularly important for uncertainty to act as a creative resource, rather than an obstacle. …”
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20649
Trends in depressive symptoms among high school students with and without health-risk behaviors in the United States: A population-based studyResearch in context
Published 2025-02-01“…Depressive symptoms increased more among students engaging in ≤1 risk category (BAPC = 4.6% [3.6–5.7%]) than students engaging in 4–5 risk categories (BAPC = 2.9% [2.4–3.3%]) (interaction, p = 0.037) and there was a general trend toward decreasing engagement in risk behaviors among students with depressive symptoms. …”
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20650
Latinx and White Adolescents’ Preferences for Latinx-Targeted Celebrity and Noncelebrity Food Advertisements: Experimental Survey Study
Published 2025-01-01“…Two of the 5 behavioral intention measures differed by celebrity advertisement status (P=.02; P<.001). Additionally, the interaction between celebrity and participant ethnicity was significant for 4 behavioral intentions; Latinx, but not White, participants reported higher willingness to consume the product (P<.001), follow brands (P<.001), and tag friends (P<.001). …”
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20651
Lake pulses driven by glacier melting and climate variability
Published 2024-12-01“…By employing fast Fourier transform (FFT), multivariate regression (MVR), and random forest (RF) models, we examined the interactions among glacier melt dynamics, climatic variables, and hydrological responses. …”
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20652
Associations of Serum Cystatin C, DNAm Cystatin C, Renal Function, and Mortality in U.S. Adults
Published 2024-12-01“…This association was particularly pronounced in participants without chronic kidney disease (CKD), with a <i>p</i>-value for the interaction between DNAmCystatinC and CKD on all-cause mortality of 0.002. …”
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20653
Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis
Published 2025-01-01“…A recombinant adeno-associated virus carrying CLDN11 was used to treat experimental obesity-related SAP. The interaction between CLDN11 mRNA and insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) protein was predicted through bioinformatics analysis and validated by RNA immunoprecipitation and RNA pull-down assay. …”
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20654
In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways
Published 2025-01-01“…While molecular dynamics simulation studies supported the interactions of europinidin with important therapeutic target proteins. …”
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20655
Interpreting machine learning models based on SHAP values in predicting suspended sediment concentration
Published 2025-02-01“…These outcomes indicate that the applied models can extract accurate and detailed information from the interactions between the hydroclimatic factors and the generation of sediment by erosion (output). …”
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20656
Evaluasi Heuristik Website berbasis Framework Sirius dengan Pengaturan Prioritas menggunakan Teknik Moscow
Published 2020-02-01“…Bagi tim website Lective, kriteria usability paling penting adalah berkaitan dengan aspek labelling, sedangkan bagi pengembang website Seminar Indonesia, aspek paling penting adalah kelompok comprehensibility and ease of interaction. Adapun pengembang website Simkesmas lebih menekankan pada aspek control and feedback. …”
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20657
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20658
The StbHLH47 transcription factor negatively regulates drought tolerance in potato (Solanum tuberosum L.)
Published 2025-01-01“…Differential gene expression analysis of wild-type plants (WT) and plants overexpressing StbHLH47 (OE-StbHLH47) under drought stress revealed that the significantly differentially expressed genes were enriched in metabolic pathways, biosynthesis of various plant secondary metabolites, biosynthesis of metabolites, plant hormone signal transduction, mitogen-activated protein kinase (MAPK) signalling pathway-plant, phenylpropanoid biosynthesis, and plant‒pathogen interactions. Among these pathways, the phenylalanine and abscisic acid (ABA) signal transduction pathways were enriched in a greater number of differentially expressed genes, and the expression trends of these differentially expressed genes (DEGs) were significantly different between WT and OE-StbHLH47. …”
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20659
Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu...
Published 2025-02-01“…Although ferrptosis and macrophage polarization both play important roles in this model, their specific pathogenesis and interactions have not been elucidated. Therefore, we aimed to explore the mechanisms by which ferrotosis occurs in renal tubular epithelial cells (RTECs) and ferroptotic cell-derived exosomes induce macrophage polarization in IRI-related RIF model.MethodsIn vivo, C57BL/6J mice were randomly divided into four groups: sham group, ischemia and reperfusion (IR) group, IR + Ferrostatin-1 (Fer-1) group, and IR +ATF3 knockdown (ATFKD) group. …”
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20660
Microbial assisted alleviation of nickel toxicity in plants: A review
Published 2025-01-01“…The microbe-assisted phytoremediation further optimizes the nickel detoxification processes by fostering beneficial interactions between microbes and the nickel-hyperaccumulators; promoting enhanced metal uptake, transformation, and sequestration. …”
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