Efficacy of combined colorectal cancer treatment in senile patients by P. V. Tsarkov, D. R. Markaryan, V. M. Nekoval

“…Due to complex drugto-drug interactions specificity of metabolism and biological tumor properties, cross-reactions of concomitant diseases in senile patients each step of combined treatment should be discussed at multidisciplinary consultation.…”
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Pulmonary and systemic immune alterations in rats exposed to airborne lunar dust by Brian E. Crucian, Heather Quiriarte, Chiu-wing Lam, Mayra Nelman, Audrie A. Colorado, Douglass M. Diak, John T. James

“…Assays included leukocyte distribution by multicolor flow cytometry and electron/fluorescent microscopy to visualize cell–particulate interactions and lavage/plasma cytokine concentration. …”
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Comparison of new secondgeneration H1 receptor blockers with some molecules; a study involving DFT, molecular docking, ADMET, biological target and activity by Velid Unsal, Erkan Oner, Reşit Yıldız, Başak Doğru Mert

“…The best binding sites of Desloratadine, Levocetirizine, Fexofenadine, CAPE, Quercetin, Melatonin, curcumin, Vitamin C ligands to Desmoglein 1, Human Histamine H1 receptor, IgE and IL13 protons were determined by molecular docking method and binding energy and interaction states were analyzed. Fexofenadine and Quercetin ligand showed the most effective binding affinity. …”
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Knowledge Management System Berbasis Web tentang Budidaya Hidroponik untuk Mendukung Smart Society by Ariq Cahya Wardhana, Yani Nurhadryani, Sri Wahjuni

“…Knowledge map is used for codification of knowledge that produces 34 explicit knowledge in the form of interactive media in the form of videos and documents that can be used by user. …”
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Characteristics Associated with Successful Residency Match in General Surgery by Reagan A. Collins, BA, Kaitlyn Nimmer, BA, Salma A. Sheriff, BS, Tania K. Arora, MD, Anai N. Kothari, MD, MS, Carrie Cunningham, MD, MPH, Callisia N. Clarke, MD, MS

“…Program directors heavily factored step 1 and step 2 scores, letters of recommendation, interactions with faculty and trainees, and interpersonal skills when interviewing and ranking applicants. …”
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Enhancing Pan evaporation predictions: Accuracy and uncertainty in hybrid machine learning models by Khabat Khosravi, Aitazaz A. Farooque, Amir Naghibi, Salim Heddam, Ahmad Sharafati, Javad Hatamiafkoueieh, Soroush Abolfathi

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Association of sex and aspirin use with postoperative bleeding in patients with lower extremity long bone fractures by Michael Fisher, Kristin Salottolo, David Bar-Or, Matthew Carrick, Kaysie L Banton, Robert Madayag, Chad M Corrigan

“…However, biological sex at birth (M/F) was a significant effect modifier (interaction p=0.04). Among women, there were significantly more postoperative bleeds for aspirin users (17.8% aspirin vs 7.4% no aspirin, adjusted OR (AOR): 2.48 (1.28–4.81), p=0.01). …”
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Predicting 28-day all-cause mortality in patients admitted to intensive care units with pre-existing chronic heart failure using the stress hyperglycemia ratio: a machine learning-... by Xiao-han Li, Xing-long Yang, Bin-bin Dong, Qi Liu

“…Subgroup analysis found that none of the potential risk factors, such as demographics, comorbidities, and drugs, affected the relationship (P for interaction > 0.05). The area under the ROC (AUC) curve for SHR was larger than those for admission blood glucose and HbA1c; the cut-off for SHR was 0.57. …”
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In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hi... by Harrison Onyango, Patrick Odhiambo, David Angwenyi, Patrick Okoth

“…The root means square deviation (RMSD) values of the potential drug candidates informed the selection of some of them, which were docked with SARS-CoV-2 Mpro to comprehend their interactions. From the molecular docking results, the top four candidates (ZINC000254823011, ZINC000072307130, ZINC000013627512, and ZINC000009418994) against SARS-CoV-2 Mpro, with binding energies ranging from –8.2 kcal/mol to –8.6 kcal/mol, were examined for their oral bioavailability and other pharmacokinetic properties. …”
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The effects of wind farm wakes on freezing sea spray in the mid-Atlantic offshore wind energy areas by D. Rosencrans, D. Rosencrans, J. K. Lundquist, J. K. Lundquist, J. K. Lundquist, M. Optis, M. Optis, N. Bodini

“…Overall, the turbine–atmosphere interaction causes a small reduction in FSS hours within the wind plant areas, with a reduction up to 15 h in January at the 10 and 20 m heights.…”
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Mental health in children with and without ADHD: the role of physical activity and parental nativity by David Adzrago, Saanie Sulley, Faustine Williams

“…However, the three-way interaction between ADHD status, parental nativity, and physical activity was not statistically significant. …”
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Effects of Different Types of Pinching in Growth and Yield of Two Varieties of Okra (Abelmoschus esculentus L.) in Pokhara, Kaski, Nepal by Prajjwal Koirala, Rijwan Sai, Pratikshya Subedi, Chiranjibi Khadka

“…Varieties and pinching methods exhibited notable interactions in average pod weight, diameter, and length. …”
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Protective effect and mechanism of Sufentanil on acute lung injury in septic mice by Hongqiao Hou, Bowen Jiang, Aiqing Zhu, Junjun Hou, Zhe Qu, Ruping Liu, Aiqun Li

“…To this end, a protein-protein interaction (PPI) network for common targets was first constructed with Swiss Target Prediction Database, GeneCards Database, Draw Venn Diagram Software, STRING 11.5 Database, Cytoscape 3.10.0 Software and Metascape Database, and then key targets were subject to enrichment analysis by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) to obtain the key targets of Sufentanil for the treatment of pulmonary sepsis, and then verified by animal experiments. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Emerging evidence indicates that COVID-19 may lead to post-acute COVID-19 syndrome (PACS) with cardiovascular implications, potentially driven by factors such as ACE2 interaction with viruses, systemic inflammation, and endothelial dysfunction. …”
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Codeveloping an Online Resource for People Bereaved by Suicide: Mixed Methods User-Centered Study by Edouard Leaune, Kushtrim Bislimi, Pauline Lau-Taï, Héloïse Rouzé, Benoit Chalancon, Laurène Lestienne, Pierre Grandgenevre, Margot Morgiève, Nathalie Laplace, Guillaume Vaiva, Julie Haesebaert, Emmanuel Poulet

“…A website for people bereaved by suicide named “espoir-suicide” was developed that includes (1) evidence-based information on suicide prevention and bereavement, (2) testimonies of people bereaved by suicide, (3) a delayed chat to ask questions on suicide and bereavement to a specialized team of mental health professionals, and (4) an interactive nationwide resource directory. The mean system usability score was 90.3 out of 100 for 30 participants, with 93% (n=28) of them having a rating above 80. …”
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Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…Three SP-VR modules will cover key aspects of survivors’ social health needs, namely functional rehabilitation, social participation, and social interaction and recreation. The primary outcome for stroke survivors is social participation, and secondary outcomes include depressive symptoms, participation self-efficacy, physical function, functional mobility and social support. …”
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Performance evaluation and stability analysis of malt barley (Hordeum vulgare L.) varieties for yield and quality traits in Eastern Amhara, Ethiopia by Abebe Assefa, Getawey Girmay, Tesfaye Alemayehu, Alemu Lakew

“…Result The analysis of variance for grain yield and quality traits showed that the main effects of both genotypes and environments, and their interaction effect, were highly significant (P ≤ 0.01). …”
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Land use intensity differently influences soil communities across a range of arable fields and grasslands by Chenguang Gao, Johanna E.M. Schild, Gabriel Y.K. Moinet, T. Martijn Bezemer, Franciska T. de Vries, Jan Hassink, Nick van Eekeren, Kevin Beentjes, Peter M. van Bodegom

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The InBIO Barcoding Initiative Database: contribution to the knowledge of DNA barcodes of the vascular plants of north-eastern Portugal by João Queirós, Rodrigo Silva, Catarina J. Pinho, Hélia Vale-Gonçalves, Ricardo Pita, Paulo Alves, Pedro Beja, Joana Paupério, Miguel Porto

“…Metabarcoding is invaluable for understanding trophic interactions, enabling high-resolution and rapid dietary assessments. …”
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H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts by Wilhelm Bouchereau, Hong-Thu Pham, Worawalan Samruan, Van-Hong Vu, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Rangsun Parnpai, Nathalie Beaujean

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