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1821
Increase of Vascular Endothelial Growth Factor and Decrease of MCP-1 and Some Updated Epidemiology Aspects of Cystic Echinococcosis Human Cases in Calabria Region
Published 2018-01-01“…Echinococcosis diagnosis was based on imaging, serological investigations, and molecular assay. Indeed, real-time PCR indicated the presence of G2/G3 genotypes of Echinococcus granulosus complex. …”
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1822
Wisdom of the Established Pattern
Published 2023-06-01“…The resistance to violating the status quo is indeed often flavored with moral outrage toward the change. …”
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1823
Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Cont...
Published 2025-01-01“…Our analysis shows that HLA-B*57:01 is indeed associated with partially functional MICA/MICB proteins which could also explain this marker’s involvement in other diseases such as psoriasis. …”
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1824
Humoral and cellular immune durability of different COVID-19 vaccine platforms following homologous/heterologous boosters: one-year post vaccination
Published 2025-01-01“…We found that robust T cell mediated immune responses were preserved and largely induced by a heterogeneous vaccination eliciting a significantly higher CD8+ T cells IFN-γ response in 100% of vaccinees regardless of previous natural infection. Indeed, the difference between infected and naïve groups was less pronounced suggesting a reduced infection-related response.DiscussionAcross three layers of evidence, this study showed that heterologous vaccination provides longer-lasting immunity than homologous doses, regardless of prior natural infection.…”
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1825
The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity
Published 2019-01-01“….≥0.65) but also highlighted a marked variability among different patients. Indeed, the heatmap reporting Gain/Loss State for 21022 coding/noncoding genes demonstrated high interpatient divergence. …”
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1826
Persistent Gender and Racial Hierarchies: Marriage Migration and Mixedness in Morocco from the French Protectorate to the Present
Published 2023-07-01“…We argue that in post-independence Morocco, mixed marriages are no longer considered a threat to political power but that they still reveal the existence of persistent racial and gender symbolic boundaries. Indeed, social perception of mixed couples has shifted from a fear of neo-imperialism to a feeling of opportunities in a globalized world, but gender and racial hierarchies still prevail as significant symbolic boundaries that shape mixed couples and attitudes towards them.…”
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1827
Functional effect of adiponectin and body composition assessment in lung cancer subjects after video‐assisted thoracoscopic surgery (VATS) lobectomy
Published 2025-01-01“…It is a multifactorial disease characterized by epigenetic and nutritional factors. Indeed, there is a strong association between adipose tissue and the pulmonary system, and low‐grade inflammation of obese and/or overweight subjects have a pivotal role in lung cancer establishment. …”
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1828
The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil
Published 2019-01-01“…Although a wide variety of methods have been used to expand BMSCs on a large scale by using good manufacturing practice (GMP), little attention has been paid to whether the expansion procedures indeed allow the maintenance of critical cell characteristics and potency, which are crucial for therapeutic effectiveness. …”
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1829
Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice
Published 2025-02-01“…Exercise strongly modulates the immune system, inducing a plethora of dynamic responses involving the innate immune cell function and inflammatory processes that contribute to both potential health benefits and harmful side effects. Indeed, the relationship between physical exercise, stress, immunity, and metabolism serves as a paramount model of neuroimmunoendocrine interaction. …”
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1830
The immunological landscape of CCL26High invasive oral squamous cell carcinoma
Published 2025-01-01“…In addition, CCL26high OSCC was found to be associated with immunoglobulin mediated immune response, B cell mediated immunity et al. Indeed, immune checkpoint molecules (PD-L1, PD-L2, et al.) also decreased in CCL26high OSCC. …”
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1831
Sustainable alternative of palm wine analogue from different tiger nut milk-sugar syrup blends for local production
Published 2025-01-01“…Conclusions: Potentially, the (palm wine) analogue produced from tiger nut milk and sugar syrup blends using (palm wine) dreg as inoculum could be embraced by the market as natural palm wine. Indeed, the emergent product should serve as an alternative sustainable promise for palm wine, which could help fill the market supply gap, especially in the seasons of reduced supply/yield.…”
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1832
Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat
Published 2025-02-01“…Moreover, our results provided the basis for combined entinostat + EGFR inhibitor (erlotinib) treatment, and indeed we demonstrate synergistic effects in combination therapy studies. …”
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1833
The Novel Histological Prostatic Inflammation Score Helps Defining the Association Between Stromal and Glandular Inflammation with the Risk of Prostate Cancer at Prostate Biopsy
Published 2025-01-01“…The Irani score, a validated system that scores PI according to the grade of stromal infiltration (Irani G) and the aggressiveness of glandular infiltration (Irani A), has indeed been found to be inversely associated with PCa diagnosis and outcome, but the presence of two categories (G and A) makes the performance of this score suboptimal. …”
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1834
Une statue de togatus découverte dans l’agglomération antique de Briord (Ain)
Published 2023-12-01“…A Julio-Claudian togatus discovered in Barcino is a close comparison. Indeed, the Roman toga of Briord is halfway between the new trends of its period and the old Italic influences. …”
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1835
Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease
Published 2025-01-01“…There is a growing consensus that brain development in Huntington's disease (HD) is abnormal, leading to the idea that HD is not only a neurodegenerative but also a neurodevelopmental disorder. Indeed, structural and functional abnormalities have been observed during brain development in both humans and animal models of HD. …”
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1836
De la police coloniale française à la police nationale marocaine : décolonisation et héritages policiers (1953-1960)
Published 2023-12-01“…It inherits the structures of the Cherifian Police, and many French police officers remain in the Moroccan national police as collaborators (one-third of the personnel in 1957). There is indeed a process of Morocconization of the police, but it is gradual. …”
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1837
Current Enzooticity of <i>Dirofilaria immitis</i> and <i>Angiostrongylus vasorum</i> in Central and Southern Italy
Published 2025-01-01“…These results confirm that <i>D. immitis</i> is enzootic in the investigated regions of Central and Southern Italy, even where it was rare/undetected until recently. Indeed, although some dogs positive for <i>D. immitis</i> had a history of travel in enzootic areas, the majority of them were never moved, indicating that they acquired the parasite in the region where they live. …”
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1838
Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit
Published 2025-01-01“…Further research is essential to validate whether women with mild AD dementia indeed progress more rapidly than men at a similar stage and to delve into the potential underlying reasons for this finding.…”
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1839
Gravitational wave luminosity distance for Starobinsky gravity in viscous cosmological models
Published 2025-01-01“…It is worth noting that the numerical analyses to $$\delta (z)$$ δ ( z ) and $$d_L^{GW}(z)/d_L^{EM}(z)$$ d L GW ( z ) / d L EM ( z ) illustrate once again that the GW luminosity distance $$d_L^{GW}(z)$$ d L GW ( z ) is indeed influenced by $$\alpha $$ α and $$\eta $$ η , in particular more sensitive to $$\alpha $$ α than $$\eta $$ η in our model. …”
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1840
Une inscription méconnue de Cos/Cosa dans la cité des Cadurques
Published 2021-12-01“…Nothing states that the rest of the line should be completed with an official formula of the type l(ocus) d(atus) d(ecreto) d(ecurionum). Indeed, a hole is located below, perhaps for mounting purposes, which might indicate that the engraving of the last line was centered in order to highlight it. …”
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