Editorial by Ann-Kristin Kölln, Antony Mason, Jörg Tremmel, Markus Rutsche, Maria Lenk

“…The final contribution in this issue offers insights from an online survey conducted among young adults in Germany suggesting that these respondents were indeed politically interested and felt willing to assume responsibility through participation. …”
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La flore sauvage du boulevard Dr Henri-Henrot à Reims/Durocortorum : approche carpologique de l’environnement du site et des productions de denrées végétales by Véronique Matterne, Clémence Pagnoux

“…The latter may have favored the migration of plant species from soils with chalky or chalky substrates to soils in the process of alkalization due to repeated tidal flooding (Brasseur et al. 2018). Indeed, a diversity of plants with a facility for growing in more alkaline environments are well represented in the Reims assemblages and become much more so within carpological assemblages in northern France from the Late Iron Age or Roman period onward.…”
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Epidemiology of Alzheimer’s Disease and Dementia in Arab Countries: A Systematic Review by Ashraf El-Metwally, Paivi Toivola, Mashael Al-Rashidi, Shanila Nooruddin, Munazza Jawed, Raghad AlKanhal, Hira Abdul Razzak, Nada Albawardi

“…Prevalence studies demonstrated that dementia is indeed a prevalent condition in Arab countries, ranging between 1.1% and 2.3% among age groups of 50 years and older, as well as between 13.5% and 18.5% among age groups of 80 years and above. …”
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Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism by Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist

“…Knock-down or expression of a dominant-negative isoform of SARM1 indeed drastically delayed ND. Various modifications of NAD+ metabolism known to modulate SARM1 activity showed the corresponding effects on ND. …”
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The Campaign to Remove Si Kancil from Indonesian Schools (Kampanye Hapus Si Kancil dari Sekolah Indonesia) by Dipa Nugraha, Suyitno Suyitno, Elisabeth Ashton

“…It is also suggested that Si Kancil, as an Indonesian cultural artifact, should be preserved and indeed celebrated as reading material in Indonesian schools and bedtime storytelling.…”
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Integralna ochrona środowiska w nauczaniu Jana Pawła II by Wojciech Bołoz

“…God’s intention for the Earth may indeed be expanded by a human but it should not be fought against. …”
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Analysis of Glucocorticoids as Potential Adulterants in Cosmetic Products: A Dual Approach for Qualitative and Quantitative Evaluation Based on ELISA and HPLC-MS Methods by Seyedeh Rojin Shariati Pour, Afsaneh Emamiamin, Martina Zangheri, Donato Calabria, Massimo Guardigli, Emanuele Porru, Jessica Fiori, Mara Mirasoli

“…This reference method was then compared with an enzyme-linked immunosorbent assay (ELISA). Indeed, immunological techniques allow for rapid, low-cost, and sensitive detection of target analytes even in complex matrices, and they can be performed with simple instrumentation and by non-skilled personnel. …”
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Sarcopenia as a Predictor of Mortality in a Cohort of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography by Giacomo Mulinacci, Clara Benedetta Conti, Alberto Savino, Davide Gandola, Davide Ippolito, Roberto Frego, Alessandro Ettore Redaelli, Marta Maino, Marco Emilio Dinelli

“…Conclusions: SMI is an easy and objective index of sarcopenia that could be used to predict ERCP outcomes. Indeed, sarcopenia was independently associated with prolonged hospitalization and increased mortality in a retrospective cohort of elderly patients.…”
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Local Inflammation in Fracture Hematoma: Results from a Combined Trauma Model in Pigs by K. Horst, D. Eschbach, R. Pfeifer, S. Hübenthal, M. Sassen, T. Steinfeldt, H. Wulf, S. Ruchholtz, H. C. Pape, F. Hildebrand

“…Our data showed a time-dependent activation of the local and systemic inflammatory response. Indeed it is the first study focusing on the local and systemic inflammatory response to multiple-trauma in a large animal model.…”
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Oral ATP treatment in alternating hemiplegia of childhood: a case report and review by Marco Carrozzi, Maria Elisa Morelli, Mario Cirino, Alessandra Maestro, Gilda Paternuosto, Giulia Benericetti, Giada Bennati, Maura Bin, Anna Flamigni, Federico Pigato, Natalia Maximova, Egidio Barbi, Egidio Barbi, Davide Zanon

“…Compounded drug showed effectiveness and safety. Indeed, during the four-year follow-up, with the dose of adenosine-5′-triphosphate gradually increasing up to 21 mg/kg, the patient showed a substantial benefit in controlling the frequency and duration of hemiplegic episodes and an improvement in neurological deterioration.…”
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Mechanical Properties of Bump-Prone Coal with Different Porosities and Its Acoustic Emission-Charge Induction Characteristics under Uniaxial Compression by Xin Ding, Xiaochun Xiao, Xiangfeng Lv, Di Wu, Jun Xu

“…The amplitudes and accumulation of AE energy and charge pulse indeed vary with the stress loading stages and strength. …”
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Urban fruit bats give birth earlier in the season compared to rural fruit bats by Maya Weinberg, Dean Zigdon, Mor Taub, Lee Harten, Ofri Eitan, Adi Rachum, Reut Assa, Omri Gal, Yossi Yovel

“…We monitored the bats’ reproductive state and the size of the pups following parturition. Indeed, we found that urban fruit bats gave birth ~ 2.5 weeks earlier in spring than rural fruit bats. …”
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Therapeutic bullfrog oil-based nanoemulsion for oral application: Development, characterization and stability by Rutckeviski Renata, Xavier Francisco Humberto, Morais Andreza Rochelle Do Vale, Amaral-Machado Lucas, Alencar Everton Do Nascimento, Genre Julieta, De Souza Araujo Adriano Antunes, Egito Eryvaldo Socrates Tabosa Do

“…The optimized oral nanoemulsion showed a milky single-phase and optimal physical stability at 25 °C for 90 days. Indeed, higher oxidation induction time and lower formation of peroxides in the oral nanoemulsion were responsible for improving its stability. …”
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Genetic ancestry and the colonial legacies of race in genomics: a cross-disciplinary dialogue by Ernesto Schwartz-Marin, Tayyaba Jiwani, Sarah Abel, Yulia Egorova, Amade M’charek, Diogo Meyer, Andrés Moreno Estrada, Katharina Schramm, Peter Wade, Michel Naslavsky, Michel Naslavsky

“…The result is an engaging and insightful dialogue on questions that have vexed the field for decades. How do we—indeed “can” we reconcile the boundaries of biological and social difference? …”
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Idiopathic Central Precocious Puberty Associated with 11 Mb De Novo Distal Deletion of the Chromosome 9 Short Arm by Mariangela Cisternino, Erika Della Mina, Laura Losa, Alexandra Madè, Giulia Rossetti, Lorenzo Andrea Bassi, Giovanni Pieri, Baran Bayindir, Jole Messa, Orsetta Zuffardi, Roberto Ciccone

“…Although we cannot exclude that precocious puberty in our del(9p) patient is a coincidental finding, the report of the other two patients with 9p deletions and precocious puberty indeed suggests a causative relationship.…”
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Variation Characteristics of the Main Hydrochemical Indexes in Typical Subterranean Rivers in the South China Karst Region Based on Curve Fitting by Shuyi Liu, Chuan Liang, Lina Wang, Lingwei Zeng, Chunyi Wang

“…Based on the results, the following conclusions can be drawn: the development of the subterranean rivers is indeed a slow process, but water quality can change rapidly in response to the transformation of industrial society. …”
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Up-flow anaerobic sludge blanket bioreactor for the production of carboxylates: effect of inocula on process performance and microbial communities by Adrián Lago, Silvia Greses, Inés Moreno, Cristina González-Fernández

“…As a consequence of the operational conditions (25 ºC, pH = 5.5-6, organic loading rate (OLR) = 3 gCOD·L-1·d-1 and hydraulic retention time (HRT) = 10 d), the microbial communities changed from those typical for biogas production to those specialised in the production of volatile fatty acids (VFAs). Indeed, the highest bioconversion efficiency (70.1%) was obtained with BGS, where uncultured Eubacteriaceae family microorganisms (56.0%) prevailed, enhancing the production of butyric acid (59.5 ± 2.4%w/w). …”
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Detection of serum composition in pediatric inflammatory multisystem syndrome associated with SARS-CoV-2 and the response for the treatment by FTIR by Joanna Depciuch, Izabela Sieminska, Pawel Jakubczyk, Bartosz Klebowski, Katarzyna Ptak, Izabela Szymońska, Przemko Kwinta, Maciej Siedlar, Jan Jakub Kęsik, Magdalena Parlinska-Wojtan, Jarek Baran

“…The difference in the chemical compositions of sera from the control group and the children after the treatment was detected in 54%, indicating that the treatment was effective. Indeed, the obtained medical data clearly showed a decrease of C-reactive protein (CRP) and Procalcitonin (PCT) concentration in serum after the treatment. …”
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EFFECTS OF BIRTH TYPE ON FATTENING PERFORMANCE AND CARCASS CHARACTERISTICS OF D’MAN LAMBS IN SOUTHWESTERN ALGERIAN OASES by Boubekeur Abderrahmen, Souddi Mohammed, Benidir Mohammed

“…In conclusion, birth type affected the fattening performances and carcass characteristics of D'man lambs. Indeed, the fattening performance and slaughter characteristics of single-born D'man lambs were higher than twins and triplets. …”
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Chemical and sensory differentiation of Nemea PDO sub-zones wines: two vintages experiment by Miliordos Dimitrios Evangelos, Goulioti Elli, Lola Despina, Kanapitsas Alexandros, Kontoudakis Nikolaos, Kotseridis Yorgos

“…Notably, the presence of some volatile compounds in wines was indeed impacted by grape origin. In essence, this research illustrated how the sensory attributes of ‘Agiorgitiko’ wines could be changed by diverse terroir elements within the designated Nemea wine region.…”
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