Altered shear stress of blood flow causes plasma membrane damage in endothelial cells by Nikita Raj, Chang Pan, Ann Marleen Starke, Anna L. L. Matos, Oliver Soehnlein, Volker Gerke

“…However, whether SS of blood flow can indeed affect plasma membrane integrity of endothelial cells and whether any ruptures occurring are repaired is not understood. …”
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The Potential of Virtual Reality for Inducing Neuroplasticity in Children with Amblyopia by María B. Coco-Martin, David P. Piñero, Luis Leal-Vega, Carlos J. Hernández-Rodríguez, Joaquin Adiego, Ainhoa Molina-Martín, Dolores de Fez, Juan F. Arenillas

“…Several clinical researches on this issue have been conducted, showing the potential of promoting visual acuity, contrast sensitivity, and stereopsis improvement. Indeed, several systems have been evaluated for amblyopia treatment including the use of different commercially available types of head mounted displays (HMDs). …”
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Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations by Nelly Joseph-Mathurin, Olene Dorieux, Audrey Kraska, Anne Bertrand, Mathieu Santin, Nadine El Tannir El Tayara, Marc Dhenain

“…Mouse lemur (Microcebus murinus) is a small primate (about 12cm, 100g) described as a useful model of cerebral aging and as a potential model of AD. Indeed several animals develop age-associated cerebral alterations like amyloidosis and other cerebral changes. …”
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Valorization of various sources of rabbit manure in agro-piscicultural system in Benin (West Africa): dynamics and effect of mineralization upon quality of fresh water by Richard Adande, Hervé Kouessivi Janvier Bokossa, Mouhamadou Nourou Dine Liady, Emile Didier Fiogbé

“…Methods The treatments consisted of manure of rabbits fed with: manufactured diet (T1), improved diet with Ipomea aquatic (T2), improved diet with Elaeis guineensis (T3), and improved diet with Panicum maximum (T4). Indeed, experimental design was a completely randomized block design with three replications. 6 g in 10 L of water from the different manures from each diet was followed during 50 days. …”
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Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature by Federico Cappellacci, Fabio Medas, Gian Luigi Canu, Maria Letizia Lai, Giovanni Conzo, Enrico Erdas, Pietro Giorgio Calò

“…Parathyroid carcinoma is one of the rarest cancers in normal population, and it is extremely uncommon in the setting of tertiary hyperparathyroidism. Indeed, only 24 cases have been reported in the literature. …”
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qArI: A Hybrid CTC/Attention-Based Model for Quran Recitation Recognition Using Bidirectional LSTMP in an End-to-End Architecture by Sumayya Alfadhli, Hajar Alharbi, Asma Cherif

“…Though the application of freshly developed models to spoken and written Arabic and non-Arabic speech recognition has yielded highly accurate results, research on Holy Quran is still in its early levels. Indeed, speech recognition of the Holy Quran presents several challenges, including language complexity and the absence of a comprehensive dataset. …”
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Commonality of Virulence-Promoting Function in Rhodococcus equi Virulence Associated Proteins (Vaps) by Timothy R. Ganderton, Daniel Ghete, Karen Hogg, Graeme J. Park, Christoph G. Baumann, Anthony J. Wilkinson, Paul R. Pryor

“…We, therefore, examined whether VapK and VapN worked mechanistically in the same way as VapA. Indeed, like VapA, VapK and VapN neutralised lysosomal pH and reduced lysosomal hydrolase activity. …”
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Specialized Scalar and SIMD Instructions for Error Correction Codes Decoding on RISC-V Processors by Mael Tourres, Cyrille Chavet, Bertrand Le Gal, Philippe Coussy

“…The rapid deployment of Internet-of-Things (IoT) devices for a few years has been impressive, and the progressive deployment of 5G will accelerate things even further. Indeed, this standard opens the door to a new generation of standards aimed at a convergence of networks and communication protocols (WiFi, LTE, 4G etc.). …”
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Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma by David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

“…However, the described <10% VHL mutation rate cannot account for the high frequency of hypoxic response observed. Indeed, little is known about genetic mechanisms disrupting other complex component genes. …”
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Application of Infrared Spectroscopy for Functional Compounds Evaluation in Olive Oil: A Current Snapshot by Sarfaraz Ahmed Mahesar, Massimo Lucarini, Alessandra Durazzo, Antonello Santini, Anja I. Lampe, Johannes Kiefer

“…., based on chromatography and mass spectrometry. Indeed, the present review focuses on the application of infrared spectroscopy for functional compounds evaluation in olive oil.…”
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Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity by Salome’ V. Ibba, Mohamed A. Ghonim, Kusma Pyakurel, Matthew R. Lammi, Anil Mishra, A. Hamid Boulares

“…Protection against chronic HDM exposure-induced AHR by olaparib-mediated PARP inhibition may be associated with the partial but not the complete blockade of iNOS expression. Indeed, L-NIL administration prevented olaparib-mediated protection against AHR in chronically HDM-exposed mice. …”
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Himma K. E. The Logic of Showing Possibility Claims: A Positive Argument for Inclusive Legal Positivism and Moral Grounds of Law / trans. from English V. V. Ogleznev, D. V. Shvedov by V. V. Ogleznev, D. V. Shvedov

“…Once the structural framework is adequately developed, the argument for MIT will be grounded on the strength of a thought experiment of a surprisingly simple kind. Indeed, the argument is inspired by a Razian argument for the possibility of a legal system without coercive enforcement machinery; on his view, a society of angels could still have a system of law without any coercive machinery. …”
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Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition by Afnan Deebani, Jabila Mary, Sanchi Dhinoja, Ayah Al Qaryoute, Weam Fallatah, Pudur Jagadeeswaran

“…In parallel studies, impaired ATP synthase assembly in human cells lacking TMEM242 prompted us to hypothesize that reduced ATP synthase could elevate reactive oxygen species (ROS) levels, influencing clotting factor expression. Indeed, tmem242 knockdown increased ROS levels. Inhibition of ATP synthase with oligomycin elevated ROS and f9a transcripts, while ROS inhibition reduced f9a expression, suggesting ROS-mediated regulation. …”
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Evaluation of Antioxidant and Antimicrobial Activity of Saponin Extracts from Different Parts of Argania spinosa L. Skeels by Yousra El Idrissi, Youssef Elouafy, Hamza El Moudden, Najoua Mghazli, Chakir El Guezzane, Adil El Yadini, Hicham Harhar, Abdelkader Zarrouk, Khang Wen Goh, Long Chiau Ming, Abdelhakim Bouyahya, Mohammed Tabyaoui

“…The antioxidant activity of the samples was significantly improved from the crude shell extract (IC50 = 5.85 µg/mL) to its butanolic fraction (IC50 = 2.94 µg/mL) and its precipitate (IC50 = 1.57 µg/mL) using 2,2-diphenyl-picrylhydrazyl. Indeed, the ABTS test, showed similarity to the core results. …”
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Prediction of the critical stress to crack initiation associated to the investigation of fatigue small crack by D. Marhabi, N. Benseddiq, G. Mesmacque, Z. Azari, J.M. Nianga

“…When the short cracks are hidden in the material, we shows that the number cycles during small crack growth be significantly higher (Fig. 4) than the corresponding cycles of large cracks growth (ONI’s fatigue test) for the same physically crack size. Indeed its evolution can be blocked by a microstructural barrier (grain boundary, for example). …”
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Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem Cells by Tomohiko Akiyama, Shunichi Wakabayashi, Atsumi Soma, Saeko Sato, Yuhki Nakatake, Mayumi Oda, Miyako Murakami, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeru B. H. Ko, Minoru S. H. Ko

“…However, the efficiency of direct differentiation was rather low, most likely due to chromatin features unique to hPSCs, which hinder the access of TFs to genes involved in muscle differentiation. Indeed, recent studies have demonstrated that ectopic expression of epigenetic-modifying factors such as a histone demethylase and an ATP-dependent remodeling factor significantly enhances myogenic differentiation from hPSCs. …”
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The Optimal Timing of Strategic Action – A Real Options Approach by Gordon G. Sollars, Sorin Tuluca

“…The results presented in this paper help to clarify the ambiguity that is found in the strategic management literature regarding the possibility of obtaining a first-mover advantage. Indeed, a first mover that acts sub-optimally could incur losses or at least not gain any advantage. …”
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INterpolated FLOod Surface (INFLOS), a Rapid and Operational Tool to Estimate Flood Depths from Earth Observation Data for Emergency Management by Quentin Poterek, Alessandro Caretto, Rémi Braun, Stephen Clandillon, Claire Huber, Pietro Ceccato

“…The tool’s computational optimisations further enhance efficiency, improving computation times by up to 15-fold, compared to similar techniques. Indeed, it is able to process areas of up to 6000 ha in a median time of 5.2 min, and up to 30 min at most. …”
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Physiologic Course of Female Reproductive Function: A Molecular Look into the Prologue of Life by Joselyn Rojas, Mervin Chávez-Castillo, Luis Carlos Olivar, María Calvo, José Mejías, Milagros Rojas, Jessenia Morillo, Valmore Bermúdez

“…This vital course may be systematized in three subsequent stages: prenatal development of ovaries and germ cells up until in utero arrest of follicular growth and the ensuing interim suspension of gonadal function; onset of reproductive maturity through puberty, with reinitiation of both gonadal and adrenal activity; and adult functionality of the ovarian cycle which permits ovulation, a key event in female fertility, and dictates concurrent modifications in the endometrium and other ovarian hormone-sensitive tissues. Indeed, the ultimate goal of this physiologic progression is to achieve ovulation and offer an adequate environment for the installation of gestation, the consummation of female fertility. …”
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Teenagers with type 2 diabetes mellitus as a hidden population: A qualitative study of the representations and experiences related to the disease in Mazatlán, Mexico by Nathaly Llanes-Díaz, Dewi Hernández-Montoya

“…Identity construction is strongly affected by the disease; indeed, diabetes implied a reconstruction of male identity, while for females the disease was associated with overweight that affects their self-esteem. …”
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