Microbiota for production of wine with enhanced functional components by Armachius James, Ting Yao, Hengming Ke, Yousheng Wang

“…Moderate wine consumption, particularly red wine has been associated with functional benefits to human health, which includes anti-inflammation, promoting healthy aging, prevention of cardiovascular diseases, cancers, type 2 diabetes and metabolic syndrome. Indeed, the management of microbiota allows the production of wine with distinct features and functional components that benefits human health. …”
Get full text

Quand des pesticides empoisonnent la recherche, la réglementation et la démocratie : by Louise Vandelac

“…Gilles-Éric Seralini, a molecular biologist and university professor, subject of these persecutions which led him to file seven defamation lawsuits - all won - could have never suspected the scope and severity of these attacks whose main strings are revealed in this exceptional investigative account. Indeed, this analytical work, based on Seralini's first-hand experience and on, something utterly unique, 2.5 million pages of internal documents from Bayer-Monsanto, the Monsanto Papers, declassified during the first American trials against Bayer-Monsanto of the 125.000 victims of non-Hodgkin lymphoma (NHL), attributed to Roundup, and on the 20.000 pages where Seralini's name appears 55.952 times. …”
Get full text

Epidemic of Depression and Anxiety in child and adolescent population during COVID-19 pandemic: A systematic review and meta analysis of the prevalence of depression and anxiety by Gaurav Maggu, Vinod Verma, Suprakash Chaudhury, Vishal Indla

“…The age range varied considerably from 1 year to 19 years; 5 studies had participants aged more than 19 years, but the mean age of the total sample was less than 18 years. We conclude that indeed there is a mental health epidemic among the child and adolescent population. …”
Get full text

Identification of G-quadruplex-forming Sequences in Nucleocapsid Gene of SARS-CoV-2 Variants of Concern: An In Silico Analysis by Saeedeh Ghazaey Zidanloo

“…Therefore, due to the loss of this important PQS or indeed an obstacle to viral replication, the Delta variant could exhibit higher reproduction and pathogenicity than other variants of concern.…”
Get full text

PPARγ Expression and Function in Mycobacterial Infection: Roles in Lipid Metabolism, Immunity, and Bacterial Killing by Patricia E. Almeida, Alan Brito Carneiro, Adriana R. Silva, Patricia T. Bozza

“…Mycobacterial triggered increased PPARγ expression and activation lead to increased lipid droplet formation and downmodulation of macrophage response, suggesting that PPARγ expression might aid the mycobacteria in circumventing the host response acting as an escape mechanism. Indeed, inhibition of PPARγ enhances mycobacterial killing capacity of macrophages, suggesting a role of PPARγ in favoring the establishment of chronic infection. …”
Get full text

Exploiting Dual-Output Programmable Blocks to Balance Secure Dual-Rail Logics by Laurent Sauvage, Maxime Nassar, Sylvain Guilley, Florent Flament, Jean-Luc Danger, Yves Mathieu

“…FPGA design of side-channel analysis countermeasures using unmasked dual-rail with precharge logic appears to be a great challenge. Indeed, the robustness of such a solution relies on careful differential placement and routing whereas both FPGA layout and FPGA EDA tools are not developed for such purposes. …”
Get full text

A GDPR-compliant solution for analysis of large-scale genomics datasets on HPC cloud infrastructure by Silvia Gioiosa, Beatrice Chiavarini, Mattia D’Antonio, Giuseppe Trotta, Balasubramanian Chandramouli, Juan Mata Naranjo, Giuseppa Muscianisi, Mirko Cestari, Elisa Rossi

“…Abstract This paper outlines the technical and organizational measures implemented by the Italian supercomputing center, CINECA, to efficiently collect, process, and store sensitive-omics data in compliance with GDPR regulations. Indeed, the explosion of High Throughput Sequencing in medicine has raised tremendous opportunities for large-scale genomic data analysis. …”
Get full text

JWST Near-infrared Spectroscopy of High-albedo Jupiter Trojans: A New Surface Type in the Trojan Belt by Michael E. Brown, Ian Wong, Matthew Belyakov

“…The reflectivity of these objects does not rise redward of 4 μ m, a property that is seen in the previous JWST observations of Jupiter Trojans only in Polymele. Indeed, the high-albedo Jupiter Trojan spectra are a good match to that of Polymele, and Polymele is both the smallest Jupiter Trojan in the previous JWST sample and has the highest albedo of the objects in that sample. …”
Get full text

Moderate and Severe Level of Food Insecurity Is Associated with High Calorie-Dense Food Consumption of Filipino Households by Imelda Angeles-Agdeppa, Marvin B. Toledo, Jezreel Ann T. Zamora

“…Moreover, the results of the multiple logistic regression revealed that food insecure households have a higher likelihood to be deficient in energy, protein, calcium, vitamin A, thiamin, riboflavin, niacin, and vitamin C intakes, but except for iron (p value <0.05). Indeed, household food insecurity was associated with the higher consumption of calorie-dense food among Filipino households. …”
Get full text

Application of Cancer Genomics to Solve Unmet Clinical Needs by Se-Hoon Lee, Sung Hoon Sim, Ji-Yeon Kim, SooJin Cha, Ahnah Song

“…The large amount of data on cancer genome research has contributed to our understanding of cancer biology. Indeed, the genomics approach has a strong advantage for analyzing multi-factorial and complicated problems, such as cancer. …”
Get full text

Autoimmune Cytopenias in Chronic Lymphocytic Leukemia by Giovanni D'Arena, Roberto Guariglia, Francesco La Rocca, Stefania Trino, Valentina Condelli, Laura De Martino, Vincenzo De Feo, Pellegrino Musto

“…Pure red cell aplasia (PRCA) and autoimmune agranulocytosis (AG) are, indeed, more rarely seen. However, they are probably underestimated due to the possible misleading presence of cytopenias secondary to leukemic bone marrow involvement or to chemotherapy cytotoxicity. …”
Get full text

Qualitative study of patients experiences and perceptions of stepping down asthma medication in primary care across England by Chloe I Bloom, Adam Lewis, Jack Middleton

“…Most were inclined to step down, if clinically safe to do so, indeed some had reduced their medication doses themselves, without professional guidance.…”
Get full text

Structure and evolution of metapolycentromeres by E. O. Grishko, P. M. Borodin

“…Apparently, metapolycentromeres are more common across different species than it was believed until recently. Indeed, a systematic review of the available cytogenetic publications allowed us to identify 27 candidate species with metapolycentromeres. …”
Get full text

Comprehensive Review of Privacy, Utility, and Fairness Offered by Synthetic Data by A. Kiran, P. Rubini, S. Saravana Kumar

“…However, this needs a comprehensive evaluation before the data user can be confident enough that it is indeed a good substitute for real data. In this paper, we look at three main parameters of synthetic data which should provide a holistic assessment of the quality of synthetic data. …”
Get full text

Modeling and Numerical Analysis in 3D of Anisotropic and Nonlinear Mechanical Behavior of Tournemire Argillite under High Temperatures and Dynamic Loading by Foguieng Wembe Marius, Mambou Ngueyep Luc Leroy, Ngapgue François

“…The critical temperature from which the material damage was pronounced is 500°C. Indeed, above this temperature, the loss of rigidity of argillite reduced significantly the mechanical performance of this rock. …”
Get full text

Lessons Learnt from the Monetary System of Guernsey by Gábor Sárdi, József Varga

“…Guernsey’s money system, however, remains an important topic as its way of operation is indeed unusual in the global economy. Whereas money supply in most countries consists primarily of privately issued bank-debt money (about 95%), Guernsey (States of Guernsey) finance its public spending via quasi state issued money since 1817. …”
Get full text

Research on the Failure and Fracture Evolution of Mylonite with a Prefabricated Circular Opening by Discrete Element Method by Kunmeng Li, Yuanhui Li, Shuai Xu, Zhipeng Xiong, Long An

“…Finally, based on the uniaxial compressive strength of mylonite in the laboratory, it is inferred that the fracture pattern of mylonite with a prefabricated circular opening by theoretical analysis is indeed shear failure, which is consistent with the result of numerical simulation.…”
Get full text

Les Bas-Champs de Cayeux (Somme, France) : vers une gestion intégrée ? by Vincent Bawedin, Jean-Marc Hoeblich

“…We shall study a new kind of management in the southern part of the Baie de Somme, on a coastal area where new initiatives have been taken  consequently to the  decisions taken in the CIADT (interministerial committees for the territorial sustainable management) in April 2001 and September 2004. There, indeed, the notions of sustainable development and of GIZC have been promoted, belatedly with reference to advice of the Bonnot report (1995), and show the necessity of a proper policy concerning coastal areas, as playing no poor part in the global environmental policy. …”
Get full text

Characterization and Digital Restauration of XIV-XV Centuries Written Parchments by Means of Nondestructive Techniques: Three Case Studies by L. Pronti, M. Perino, M. Cursi, M. L. Santarelli, A. C. Felici, M. P. Bracciale

“…Furthermore, multispectral UV fluorescence imaging and multispectral VIS-NIR imaging proved to be a good approach for the digital restoration of manuscripts that suffer from the loss of inked areas or from the presence of brown spotting. Indeed, using ultraviolet radiation and collecting the images at different spectral ranges is possible to enhance the readability of the text, while by illuminating with visible light and by collecting the images at longer wavelengths, the hiding effect of brown spots can be attenuated.…”
Get full text

Real‐Time Detection, Location, and Measurement of Geoeffective Stellar Flares From Global Navigation Satellite System Data: New Technique and Case Studies by Manuel Hernández‐Pajares, David Moreno‐Borràs

“…In this work we generalize GSFLAI for the very challenging scenario of stellar superflares, with a much weaker expected geoeffectiveness on the Earth ionosphere, making it difficult to distinguish its potential footprint regarding conventional ionospheric variability sources. Indeed, we will show that, unlike GSFLAI for solar flares, the new algorithm presented here (Blind GNSS search of Extraterrestrial EUV Sources [BGEES]) is able to detect EUV flares without the previous knowledge of the position of the source, which is also simultaneously estimated, providing an additional quality check of the detection. …”
Get full text