Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts by Tino Stauber, Greta Moschini, Amro A Hussien, Patrick Klaus Jaeger, Katrien De Bock, Jess G Snedeker

“…There is a need to deepen our understanding of the underlying cell signaling pathways to unlock effective treatments. In this work, we screen cell signaling pathways in human tendinopathies and find positively enriched IL-6/JAK/STAT signaling alongside signatures of cell populations typically activated by IL-6 in other tissues. …”
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Unlocking the therapeutic potential of microalgal astaxanthin a super antioxidant in oral cancer and associated ailments by Ashokkumar Veeramuthu

“…In addition, carotenoids also enhances the effectiveness of traditional cancer treatments while minimizing their harm to healthy tissues. …”
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<i>Akkermansia muciniphila</i>: A Potential Target for the Prevention of Diabetes by Kairu He, Feiyu An, Henan Zhang, Danli Yan, Tong Li, Junrui Wu, Rina Wu

“…Thus, <i>A. muciniphil</i> and its components, including the outer membrane protein Amuc_1100, <i>A. muciniphila</i>-derived extracellular vesicles (AmEVs), and the secreted proteins P9 and Amuc_1409, are systematically summarized with respect to mechanisms of action in diabetes mellitus. Diabetes treatments that rely on altering changes in <i>A. muciniphila</i> abundance are also reviewed, including the identification of <i>A. muciniphila</i> active ingredients, and dietary and pharmacological interventions for <i>A. mucinihila</i> abundance. …”
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Enhanced Fatigue Strength of Commercially Pure Ti Processed by Rotary Swaging by Hasan ALkhazraji, Ehab El-Danaf, Manfred Wollmann, Lothar Wagner

“…Fully reversed bending fatigue tests were performed on polished hour-glass specimens of commercially pure titanium grade 1 with three different grain sizes, that were produced by severe plastic deformation (rotary swaging) and subheat treatments, in order to examine the effect of grain size on fatigue. …”
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Heart-on-a-chip: a revolutionary organ-on-chip platform for cardiovascular disease modeling by Beiqin Liu, Shuyue Wang, Hong Ma, Yulin Deng, Jichen Du, Yimeng Zhao, Yu Chen

“…Traditional preclinical models, such as 2D cell cultures model and animal model, have limitations in accurately predicting human response to cardiovascular diseases and treatments. The HoC approach addresses these shortcomings by recapitulating the microscale anatomy, physiology, and biomechanics of the heart, thereby providing a more clinically relevant platform for drug testing, disease modeling, and personalized therapy. …”
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Gene Expression Profile Analysis in Epilepsy by Using the Partial Least Squares Method by Dong Wang, Xixiao Song, Yan Wang, Xia Li, Shanshan Jia, Zhijing Wang

“…Our results here may provide new understanding for the underlying mechanisms of epilepsy pathogenesis and will offer potential targets for producing new treatments.…”
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Productivity and quality of Moina sp. cultivated with various culture medium by Taufik Shidik Adi Nugroho Shidik, Julie Ekasari, Dedi Jusadi, Mia Setiawati

“…The peaks of Moina sp. density in different treatments were achieved in different days. ChBO treatments significantly had higher productivity (P<0.05). …”
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Development of the DO₃SE-Crop model to assess ozone effects on crop phenology, biomass, and yield by P. Pande, S. Bland, N. Booth, J. Cook, Z. Feng, L. Emberson

“…Additionally, our results indicate that the variance in yield reduction is primarily attributed to the premature decrease in carbon assimilation to the grains caused by accelerated leaf senescence, which is brought forward by 3–5 d under elevated O<span class="inline-formula">₃</span> treatments.</p>…”
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Meat characteristics of buffaloes (Bubalus bub- alis) in two production systems and two slaugh- ter weights by David Hernández-Sánchez, René Rodríguez-Florentino, Luis A. de la Cruz-Cruz, Efrén Ramírez-Bribiesca, María M. Crosby Galván, Miguel Á. Mata-Espinosa, René Pinto-Ruiz

“…Twenty-eight male buffaloes uncastrated of 216 ± 21.9 kg LW were used and were randomly distributed into four treatments (T): T1 and T2, grazing buffaloes (GB), slaughtered at 400 and 600 kg LW, respectively; T3 and T4, buffaloes in intensive system (IS), slaughtered at 400 and 600 kg LW, respectively. …”
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Acaricidal and insecticidal activities of entomopathogenic nematodes combined with rosemary essential oil and bacterium-synthesized silver nanoparticles against camel tick, Hyalomm... by Bander Albogami, Hadeer Darwish, Akram Alghamdi, Ahmed BahaaEldin Darwish, Wafa Mohammed Al-Otaibi, Mohamed A. Osman, Zamzam M. Al Dhafar, Abeer Mousa Alkhaibari, Abadi M. Mashlawi, Fadi Baakdah, Ahmed Noureldeen

“…We also determined the potential effects of these treatments on the biological characteristics of H. dromedarii’s engorged females. …”
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Utilization of hydrolyzed corncob as a carbohydrate source in diets for red Nile tilapia Oreochromis niloticus by Fauzan, Muhammad Agus Suprayudi, Ichsan Achmad Fauzi, Julie Ekasari

“…The first study step was enzymatic hydrolysis using 0.4 g/kg cocktail enzyme, followed by chemical hydrolysis using hydrochloric acid (HCl) at different treatments, i.e. concentration, incubation period, and ratio. …”
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Fish oil supplementation in commercial diet on growth of Anguilla bicolor bicolor by Retno Cahya Mukti, Nur Bambang Priyo Utomo, Ridwan Affandi

“…This research applied complete randomized design with four treatments addition of fish oil, i.e. 0%, 5%, 10%, and 15%. …”
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Chaihu Shugan San and Zuogui Yin synergistically improve premature ovarian failure in a rat model via the PI3K/Akt/mTOR pathway by Fei Zhang, RuiFang Liu, ZhenLing Xu, WenJie Chen, XiYa Lu, Yang Wang

“…Results: The results showed that all three treatments significantly improved ovarian function in the POF rat model. …”
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Composición del trombo e implicaciones en la caracterización y el tratamiento en el ictus isquémico by J. Marta-Enguita, F.J.D. Machado, J. Orbe, R. Muñoz

“…The presence of these components, as well as its distribution and interrelationships have demonstrated to have effect on thrombus resistance to revascularization treatments. An adequate knowledge of this pathways has allowed to develop adjuvant therapies capable of enhance current fibrinolytic drugs and/or increase efficacy of endovascular treatments. …”
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Growth performance and survival of snakehead Channa striata juvenile with different stocking density reared in recirculation system by Adang Saputra, Tatag Budiardi, Reza Samsudin, Naufal Dwi Rahmadya

“…The result showed that the treatments did not affect the survival, growth and the ratio of RNA/DNA of snakehead juvenile. …”
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Utilizing rice-husk waste as an effective weed control mulch for Holy Basil (Ocimum sanctum ) production in a tropical environment by Vivian Ogechi Osadebe, Uchenna Noble Ukwu, Nathaniel Dauda, Ifesinachi M Nwamba, Amos Ejike Ede, Anthony I Onah

“… ·       Higher weed species diversity was observed  in plots subjected to hoe-weeded, rice husk mulched, and post-emergence herbicide treatments,  suggesting that weed management techniques can influence  the composition of weed flora…”
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Hidradenitis Suppurativa Recurrence in a Caesarean Scar by K. M. Darch, T. L. Holland, L. J. Spelman

“…HS carries a substantial burden for those who suffer from it, from the significant psychosocial impact, to the cost of the multitude of topical and systemic treatments which often do not successfully control its symptoms. …”
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'In Examining Others We Know Ourselves': Joanna Baillie on Sympathetic Curiosity, Moral Education, and Drama by Lauren Kopajtic

“…I conclude by showing that although Baillie overstates her case in some respects, the core of her argument for the moral educational role of literature is persuasive and provides a rich resource in our study of eighteenth-century treatments of passion, character, and moral education.…”
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STRETCH FORMING USING HEATED DIE by COSMIN CONSTANTIN GRIGORAȘ, BOGDAN CHIRIȚĂ, VALENTIN ZICHIL, EUGEN HERGHELEGIU, CĂTĂLIN TÂMPU, VLAD CIUBOTARIU

“…Another critical aspect of this process is to know how the material behaves under severe plastic deformation, as different alloys require different approaches that vary from step by step forming to in-process chemical treatments to manual pounding the metal sheet. However, all these alloys have in common that, when heated, their machinability properties improve. …”
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Sonication Assisted Callus Growth, Protein Content, and Plant Regeneration of Silybum marianum L. by Shifa M. Salih

“…Additionally, growth and total protein content were increased at 40 days and 80 days post- treatments. In contrast, long exposing periods (30, 35, and 40 minutes) had a negative impact on callus induction from all explants, as well as on callus growth and protein content. …”
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