Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury by Lisa Debler, Annette Palmer, Sonja Braumüller, Bettina Klohs, Tom Eirik Mollnes, Karlheinz Holzmann, Markus Huber-Lang, Rebecca Halbgebauer

“…The immune response following trauma represents a major driving force of organ dysfunction and poor outcome. …”
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Identification of clinical subgroups in anti-SRP positive immune-mediated necrotizing myopathy patients using cluster analysis by Beibei Cui, Hongjiang Liu, Ruiting Liu, Geng Yin, Qibing Xie

“…Background: Anti-signal recognition particle immune-mediated necrotizing myopathy (anti-SRP IMNM) is a rare autoimmune disorder characterized by muscle weakness and necrosis. …”
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Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis by Jian Zhang, Xiaomei Li, Ying Hu, Bin Dong, Yongning Jia, Ziyu Li, Xiaojing Cheng, Jinyao Shi, Jiafu Ji, Zhongwu Li, Hong Du, Ting Guo, Shuqin Jia, Xiaofang Xing, Yunsheng Dou

“…Background The combination of immune checkpoint blockade and chemotherapy has revolutionized the treatment of advanced gastric cancer (GC). …”
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Characterization of the Immune Response Induced by a Commercially Available Inactivated Bluetongue Virus Serotype 1 Vaccine in Sheep by Ana Cristina Pérez de Diego, Pedro José Sánchez-Cordón, Ana Isabel de las Heras, José Manuel Sánchez-Vizcaíno

“…The protective immune response generated by a commercial monovalent inactivated vaccine against bluetongue virus serotype 1 (BTV1) was studied. …”
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Tumor immune dysfunction and exclusion evaluation and chemoimmunotherapy response prediction in lung adenocarcinoma using pathomic-based approach by Wei Nie, Liang Zheng, Yinchen Shen, Yao Zhang, Haohua Teng, Runbo Zhong, Lei Cheng, Guangyu Tao, Baohui Han, Tianqing Chu, Hua Zhong, Xueyan Zhang, Xiangxiang Pan

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Visceral Leishmaniasis and Herpes Zoster as a Component of Syndrome of Immune Reconstitution Inflammatory Syndrome in an HIV-Positive Patient by Ermira Muço, Arta Karruli, Neada Hoxha, Alma Hoxhaj, Majlinda Kokici

“…Immune reconstitution syndrome (IRIS) is a state of unusual hyperinflammatory response against latent infections which occurs after CD4 cell count improvement and as a consequence of immune response once highly active antiretroviral therapy for HIV is introduced. …”
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ENHANCEMENT OF ARTIFICIAL IMMUNE SYSTEMS FOR THE TRAVELING SALESMAN PROBLEM THROUGH HYBRIDIZATION WITH NEIGHBORHOOD IMPROVEMENT AND PARAMETER FINE-TUNING by Peeraya THAPATSUWAN, Warattapop THAPATSUWAN, Chaichana KULWORATIT

Subjects: “…Artificial Immune Systems…”
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Circulating Interleukin-6 (but Not Other Immune Mediators) Associates with Criteria for Fried’s Frailty among Very Old Adults by Gilberto Santos Morais Junior, Diego Ignacio Valenzuela Perez, Audrey Cecília Tonet-Furioso, Lucy Gomes, Karla Helena Coelho Vilaça, Vicente Paulo Alves, Clayton Franco Moraes, Otávio Toledo Nóbrega

“…Frailty is a geriatric condition resulting from physiological changes covering the musculoskeletal, immune, and neuroendocrine systems, leading to a greater inflammatory state. …”
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Pro- and Anti-Inflammatory Cytokines during Immune Stimulation: Modulation of Iron Status and Red Blood Cell Profile by A. M. Koorts, P. F. Levay, P. J. Becker, M. Viljoen

“…The elevated CRP group had iron and red blood cell (RBC) profiles characteristic of chronic immune stimulation (CIS), and the normal CRP group, profiles of true iron deficiency. …”
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Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles by Paola A. Castagnino, Derick A. Haas, Luca Musante, Nathalia A. Tancler, Bach V. Tran, Rhonda Kean, Alexandra R. Steck, Luis A. Martinez, Elahe A. Mostaghel, D. Craig Hooper, Felix J. Kim

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Enhanced Electrochemiluminescence from Ruthenium-Tagged Immune Complex at Flexible Chains for Sensitive Analysis of Glutamate Decarboxylase Antibody by Yuyao Zhang, Li Qian, Qian Zhang, Yu Li, Yu Liu, Dechen Jiang

“…The electrochemical characterizations confirm the loose structure of the assembled layer with the immune complex, providing an increase in the current and the resultant enhanced ECL emissions. …”
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Alkylresorcinols as a New Type of Gut Microbiota Regulators Influencing Immune Therapy Efficiency in Lung Cancer Treatment by Aleksandr V. Shestopalov, Oleg I. Kit, Anastasia A. Zabolotneva, Elena Y. Zlatnik, Aleksey Yu Maksimov, Inna A. Novikova, Alexander B. Sagakyants, Sofya V. Timofeeva, Anna S. Goncharova, Anastasia V. Galina, Svetlana A. Appolonova, Pavel A. Markin, Valentin V. Makarov, Sergey M. Yudin, Anton A. Keskinov, Sergei A. Roumiantsev, Oleg I. Meshkov

“…Alkylresorcinols (ARs) are polyphenolic compounds of microbial origin with a wide spectrum of biological activities and are potentially involved in host immune functioning. The present study is aimed at evaluating alterations in AR content in blood serum and faeces from healthy donors and patients with lung cancer in connection with response to immune checkpoint inhibitor (ICI) therapy to estimate the regulatory potential of AR. …”
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The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis by Song Hu, Yundong Wang, Hongbing Li

“…In recent years, studies have found that the body’s cholinergic system can spontaneously and dynamically regulate inflammation and immunity in sepsis according to the needs of the body. …”
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Correlation between immune signature and high‐density lipoprotein cholesterol level in stage II/III colorectal cancer by Yun Wang, Xiao‐qiang Sun, Hao‐cheng Lin, De‐shen Wang, Zhi‐qiang Wang, Qiong Shao, Feng‐hua Wang, Shu‐mei Yan, Jie‐ying Liang, Zhao‐lei Zeng, Huai‐qiang Ju, Rui‐hua Xu, Yu‐hong Li

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Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer by Jarupa Soongsathitanon, Pranisa Jamjuntra, Nuttavut Sumransub, Supaporn Yangngam, Marjorie De la Fuente, Glauben Landskron, Peti Thuwajit, Marcela A. Hermoso, Chanitra Thuwajit

“…Chronic inflammation and the infiltration of immune cells in breast cancer (BC) have been strongly associated with early carcinogenic events and a switch to a more immunosuppressive response. …”
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Rapid Onset Severe Immune Thrombocytopenia following mRNA COVID-19 Vaccine in a Young Patient by Jorge Avila, Huseyin Berk Degirmenci, Pamela Contreras Chavez, Elisabeth M. Battinelli, Jorge Fleisher

“…Nucleocapsid antibodies against COVID-19 were found to be positive which indicated that vaccination was at least the second encounter with this virus for our patient, which has been reported previously as the cause of immune thrombocytopenia (ITP), and this might be the culprit for sudden onset. …”
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Virus-like particle: a nano-platform that delivers cancer antigens to elicit an anti-tumor immune response by Weisen Ning, Sheng Yan, Yongyao Song, Hanning Xu, Jinling Zhang, Xiaomei Wang

“…Leveraging their unique structural attributes and facile modification capabilities, VLPs can serve as an effective platform for the delivery of tumor antigens, thereby stimulating the immune system and facilitating the eradication of tumor cells.…”
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Ectonucleotidase expression on T-helper cells as a response assessment tool to immune-checkpoint therapy in head and neck cancers by B. Arvind, Praneetha Puvvula, Shalini Thakur, Anand Subash, VishalUS. Rao

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The Effect of Platelet and Mean Platelet Volume Levels on Standard-dose Methylprednisolone Treatment Response in Primary Immune Thrombocytopenia by Emrah KILICASLAN, Murat YILDIRIM, Selim SAYIN, Erdem CEVIK, Meltem AYLI, Muhammet Kursat KAPTAN

Subjects: “…immune thrombocytopenia…”
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Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation by Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma

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