A Review on the Role of Human Solute Carriers Transporters in Cancer by Md. Shafiul Hossen, Mohammed Shafin Ul Islam, Mohammad Yasin, Mohammed Ibrahim, Abhijit Das

“…Thus, SLC transporters become a potential therapeutic target that plays a crucial role in drug resistance, tumor microenvironment regulation, and modulation of immune response. Conclusion The review recognized the crucial role of SLC transporters in different types of cancer progression. …”
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A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets by Xinghao Fu, Feihong Ji, Qi He, Xinguang Qiu

“…Then, we contained a variety of elements, for instance, gene expression, the state of survival, gene alterations, protein phosphorylation, immune infiltration, and related cellular pathways, and used a series of bioinformatics methods to investigate the underlying molecular mechanism of YY1 in the etiology or clinical prognosis of various malignancies. …”
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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Food-based therapies may favorably modulate gut microbiota composition and enhance the intestinal epithelial integrity or decrease the proinflammatory response by direct effects on immune cells. Diets rich in pre- and probiotics, polyunsaturated fatty acids, phenols including flavonoids, and vitamins, such as the Mediterranean diet or a plant-based diet, may attenuate chronic inflammation and positively influence PD symptoms and even progression of the disease. …”
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Differentiated Regional (Dis)Integration Post Brexit by M. V. Strezhneva

“…This theory serves to reconsider the established renderings of such key notions, as integration, disintegration and differentiation.The new sight is gained of immune after-effects of prior Europeanization for the political system of the UK. …”
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Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung. by Annette E LaBauve, Matthew J Wargo

“…These sphingolipids not only play a structural role in lipid membranes, but some are also intracellular and intercellular signaling molecules important in normal eukaryotic cell functions as well as orchestrating immune responses. The members of the SphR transcriptome were identified by microarray analyses, and DNA binding assays showed specific interaction of these promoters with SphR, which enabled us to determine the consensus SphR binding site. …”
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Developmental inequity and the impact of pesticide exposure on gut and brain health in developing nations – a Brazilian perspective by Jessica Gama, Bianca Cruz Neves, Antonio Pereira

“…The gastrointestinal tract, home to a complex microbiome, plays an essential role in immune regulation and neurological functions. Pesticide exposure, which may begin prenatally through maternal pathways and continue postnatally, has the potential to disrupt this microbiome and affect critical neurodevelopmental processes, likely altering lifelong health outcomes. …”
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Modified rice bran arabinoxylan as a nutraceutical in health and disease-A scoping review with bibliometric analysis. by Soo Liang Ooi, Peter S Micalos, Sok Cheon Pak

“…As an oral supplement taken as an adjuvant during chemoradiotherapy, cancer patients reported reduced side effects and improved quality of life in human studies, indicating RBAC's impact on the psycho-neuro-immune axis. RBAC has been studied in 17 conditions, including cancer, liver diseases, HIV, allergy, chronic fatigue, gastroenteritis, cold/flu, diabetes, and in healthy participants. …”
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BK Virus Load Associated with Serum Levels of sCD30 in Renal Transplant Recipients by Haidar A. Shamran, Salma N. Malik, Jinan M. Al-Saffer, Rana S. Jawad

“…Complicated and overlapping factors, mainly related to the immune system, are responsible for this rejection. …”
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Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…There is a need to study of possible effects of altered microbiome on drug interactions and the immune status. The model of bacterial involvement in colorectal cancer progression is under study. …”
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Challenges and prospects for developing genetic resistance in common wheat against stem rust in Western Siberia by V. N. Kelbin, E. S. Skolotneva, E. A. Salina

“…Wheat resistance genes Sr2, Sr6Ai#2, Sr24, Sr25, Sr26, Sr31, Sr39, Sr40, Sr44, and Sr57 are of practical interest for advanced wheat breeding programs for stem rust immunity in Western Siberia. This review provides an analysis of the gene sources that remain effective against the West Siberian population of P. graminis, in order to facilitate the initial stage of selection of breeding material to develop a stable genotype by gene pyramiding. …”
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TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies by Wolfgang Eberhardt, Usman Nasrullah, Josef Pfeilschifter

“…In addition to its originally described function in antiviral innate immune response, TRIM25 can play critical yet context-dependent roles in apoptotic- and non-apoptotic-regulated cell death pathways, including pyroposis, necroptosis, ferroptosis, and autophagy. …”
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TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART by HariOm Singh, Dharmesh Samani, Sumit Aggarwal

“…Toll-like receptors (TLRs) play an important role in the innate immune response to HIV infection. Single nucleotide polymorphism (SNP) in TLR7 (Gln11Leu) gene has been associated with a rapid decline of CD4T cell count. …”
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Examining Emphysematous Pyelonephritis: A Case Study on Diagnosis and Outcomes by Mahnoor Mahnoor, Syeda Aina Ali, Saira Nasir, Moiz Azmat, Hafiz Muhammad Umer Farooqi

“…Patients with diabetes mellitus (DM), an endocrine disease with hyperglycemia, are particularly susceptible to the EPN as their immune system is compromised in fighting against infections. …”
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Expanded taxonomies of human memory by Jason R. Finley

“…The second expansion encompasses numerous biological systems beside the brain, including the immune system, genetics (DNA and epigenetics), and traces of the past stored elsewhere in the body (skin, hair, body modification, nails, bones and teeth, muscles and movement, voice, digestion and excretion, blood, reproductive systems, fat, lungs, and body-based numerical representation). …”
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Natural Cytotoxicity Receptors in Decidua Natural Killer Cells of Term Normal Pregnancy by Hideki Takahashi, Tatsuo Yamamoto, Motomi Yamazaki, Takayuki Murase, Takayuki Matsuno, Fumihisa Chishima

“…To investigate the changes in the maternal immune system at term pregnancy, we studied the expression of natural cytotoxicity receptors (NCRs) and the cytokine production of NK cells in term placenta decidua and peripheral blood. …”
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Identification of Differentially Expressed Genes in COVID-19 and Integrated Bioinformatics Analysis of Signaling Pathways by Linjie Fang, Tingyu Tang, Mengqi Hu

“…Then, based on GSEA, the enrichment of the gene set in the sample was analyzed in the GO terms, and the gene set was enriched in the positive regulation of myeloid leukocyte cytokine production involved in immune response, programmed necrotic cell death, translesion synthesis, necroptotic process, and condensed nuclear chromosome. …”
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Clinical Characteristics and Outcomes in Patients with Chronic HBV Infection and Hospitalized for COVID-19 Pneumonia: A Retrospective Cohort Study by Lucio Boglione, Maria Grazia Crobu, Mario Pirisi, Carlo Smirne

“…The effects of a concomitant infection of hepatitis B virus (HBV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are still debated, with a recognized major risk of HBV reactivation during immune-suppressive treatments. The aim of this study was to determine the prevalence and predictive factors of HBV reactivation in a cohort of hospitalized patients with coronavirus disease 2019 (COVID-19) and a current or past hepatitis B infection. …”
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Breeding columnar apple-tree cultivars for supercompact growth habit by S. A. Korneeva, E. N. Sedov, T. V. Yanchuk

“…This work was based on the combinatorial breeding technique using donors of the columnar growth type (Co gene), sources of winter hardiness and high consumer qualities, and scab immunity donors (Rvi6 gene). The selection in the columnar apple-tree hybrid progeny was accompanied by the assessment of growth vigor, compactness degree, and seedling cultivability in accordance with the guidelines.Due to the increasing popularity of apple trees with the columnar crown type, the volume of breeding work for columnar growth  habit  at  the  Russian  Research  Institute  of  Fruit  Crop  Breeding  (VNIISPK)  over  the  past  9 years  amounted  to 133,582 flowers, or one third of the entire hybridization envisaged by the apple-tree breeding program. …”
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Drug delivery systems for oral cancer treatment: A patent perspective by Mohamed Hassan Dehghan, Abrar Abdul Malik Siddiqui

“…Patents encompass siRNA, antibodies, immune checkpoint inhibitors, antimicrobial peptides, natural products like curcumin, nanoparticle drug carriers, and bioadhesive electrospun fibers loaded with drugs. …”
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5-Methoxytryptophan Alleviates Dextran Sulfate Sodium-Induced Colitis by Inhibiting the Intestinal Epithelial Damage and Inflammatory Response by Yanling Wang, Jun Li, Qinyuan Yang, Zhenhang Zhu, Fang Cheng, Xiangyan Ai, Yang Liu, Dongbao Zhao, Futao Zhao, Peng Cheng

“…In addition to its effects on immune cells, 5-MTP significantly inhibits intestinal epithelial cell tight junction damage and apoptosis in vivo. …”
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