A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient by Uchechukwu Ibewuike, MBBS, John Kim, MD, Swati Mody, MBBS, Gregory Obala, MD, Ebere Ibezim, MBBS

“…Acute motor axonal neuropathy (AMAN), a subtype of Guillain-Barré Syndrome, arises from an atypical immune response, frequently initiated by infections caused by Campylobacter jejuni, although other infectious agents have also been identified. …”
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Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myoca... by Enrique Gallego-Colon, Robert D. Sampson, Susanne Sattler, Michael D. Schneider, Nadia Rosenthal, Joanne Tonkin

“…Taken together, these results indicate that the IGF-1Ea transgene shifts the balance of innate immune cell populations early after infarction, favouring a reduction in inflammatory myeloid cells. …”
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Hemophagocytic syndrome: Laboratory and molecular characterization by Nooran Salem Yaseen, Sadiq Khalaf Ali, Hussam Saadi Aziz

“…BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of fever, cytopenia, and organomegaly resulting from immune activation and cytokine storm. The syndrome can occur as a primary/familial form mostly affecting infants and young children or as an acquired form secondary to an underlying pathology (infection, malignancy, and autoimmune disease) that may have an underlying genetic predisposition, including mutations or polymorphisms. …”
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Major Outer Membrane Protein from Legionella pneumophila Inhibits Phagocytosis but Enhances Chemotaxis of RAW 264.7 Macrophages by Regulating the FOXO1/Coronin-1 Axis by Zehui Yang, Yingying Chen, Qiang Zhang, Xiaodong Chen, Ze Deng

“…Target genes were detected by double-luciferase and pull down assays. qRT-PCR and Western blot were performed to analyze the expression of several important proteins involved in the immune response pathway, including coronin-1, interleukins (IL-10), forkhead transcription factor 1 (FOXO1), nucleotide-binding oligomerization domain protein (NOD) 1, NOD2, and receptor-interacting protein (RIP) 2. …”
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Effects of recombinant human growth hormone in severe neurosurgical patients: A single center, retrospective study. by Xixian Liao, Haorun Huang, Binghui Qiu, Jiaping Chen, An Zhang, Haoxin Liang, Chuanping Huang, Fen Mei, Jian Mao, Fan Liu, Ming Jin, Xiaojie Peng, Haidie Ma, Wenjie Ding, Songtao Qi, Yun Bao

“…<h4>Purpose</h4>To explore the effects of recombinant human growth hormone (r-hGH) on inflammatory mediators, immune cells and prognosis in severe neurosurgical patients.…”
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Association of platelet-to-lymphocyte ratio with 1-year all-cause mortality in ICU patients with heart failure by Xinyu Hu, Shijiao Cheng, Huaan Du, Yuehui Yin

“…By reflecting systemic inflammation and immune dysregulation, PLR offers a robust tool for long-term risk stratification and personalized management of ICU patients with HF. …”
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Elegant and Innovative Recoding Strategies for Advancing Vaccine Development by François Meurens, Fanny Renois, Uladzimir Karniychuk

“…Recoding enhances the frequency of CpG dinucleotides, which in turn activates immune responses and ensures a strong attenuation of the pathogens. …”
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Phthisis Bulbi in a Retinitis Pigmentosa Patient after Argus II Implantation by Logan Vander Woude, Ramak Roohipour, Gibran Syed Khurshid

“…The theoretical causes of phthisis bulbi after Argus II implantation include fibrous downgrowth, ciliary shut down due to immune reaction, inflammation, or trauma. While the cause of phthisis in this Argus patient is not certain and possibly multifactorial, it is important to note that phthisis is a possible complication of an Argus II implant, as this patient had no other obvious insult or reason for the phthisical change.…”
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De Novo Onset of Myasthenia Gravis after Kidney Transplantation by Aaron de Souza, Rajesh Raj

“…This illness is surprising since immunosuppression after transplant is usually sufficient to prevent immune-mediated disease. This patient had no history of similar illnesses. …”
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Evaluation of CD4+ T Lymphocyte Counts to Predict Survival of ICU Patients with Sepsis Using Sepsis-3 Criteria: A Prospective Cohort Study by Guoge Huang, Xusheng Li, Chunmei Zhang, Haizhong Li, Mengling Jian, Chunyang Huang, Yingqin Zhang, Luhua Xian, Hongke Zeng, Yuanyuan Xia, Wenqiang Jiang

“…T lymphocyte subsets may reflect the immune function of sepsis patients. The purpose of this study was to investigate the predictive value of CD4+ T lymphocyte counts of ICU patients for their short-term prognosis. …”
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A Quantitative Method for Detecting Ara h 2 by Generation and Utilization of Monoclonal Antibodies by Huifang Chen, Zehong Zou, Ailin Tao

“…The aim of this study was to develop a quantitative method for detecting peanut allergen using monoclonal antibodies against Ara h 2. The splenocytes of immunized mice were fused with myeloma cells (SP2/0), and stable mAb-producing clones were obtained by limiting dilution. mAbs against Ara h 2 were isolated from mouse ascites, and specificity was confirmed by immunoblotting. …”
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Ineffectiveness of hepatitis B vaccination in cirrhotic patients waiting for liver transplantation by Edith Villeneuve, Jean Vincelette, Jean-Pierre Villeneuve

“…It is common practice to immunize these patients against HBV, but the efficacy of vaccination is uncertain. …”
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Environmental noise exposure and autoimmune diseases: Evidence from a national cohort study by Seunghyun Lee, Yongho Lee, Wanhyung Lee, Xiaoxue Ma

“…Exposure to environmental noise is an inevitable factor and may pose a risk to health conditions, even potentially affecting the immune system. However, the relationship between noise exposure and autoimmune diseases has not been well explored. …”
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Characterization of m6A Methylation Modification Patterns in Colorectal Cancer Determines Prognosis and Tumor Microenvironment Infiltration by Qingfang Yue, Yuan Zhang, Fei Wang, Fei Cao, Jun Bai, Xianglong Duan

“…Cumulative studies have suggested that dysregulation of m6A regulators and immunity is highly linked to the prognosis of patients with cancer. …”
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Direct Comparison of the Safety and Efficacy of Ferric Carboxymaltose versus Iron Dextran in Patients with Iron Deficiency Anemia by Iftikhar Hussain, Jessica Bhoyroo, Angelia Butcher, Todd A. Koch, Andy He, David B. Bregman

“…Adverse events, including immune system disorders (0% in FCM versus 10.3% in DEX, P=0.003) and skin disorders (7.3% in FCM versus 24.4% in DEX, P=0.004), were less frequently observed in the FCM group. …”
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Serum Levels of VWF, t-PA, TNF-α, and ICAM-1 in Patients Receiving Hemocoagulase Combined with Platelet-Rich Plasma during Total Hip Replacement by Yaobin Huang, Bin Zhou, De Zhang, Yu Chen

“…The application of hemocoagulase combined with PRP in THR can reduce perioperative blood loss, increase wound healing speed and quality, and improve coagulation and immune function. It is a safe and effective method for the patients with knee osteoarthritis who underwent THR.…”
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Transcriptional Profiling of Testis Development in Pre-Sexually-Mature Hezuo Pig by Zunqiang Yan, Qiaoli Yang, Pengfei Wang, Shuangbao Gun

“…Additionally, chemokine, B cell receptor, activation of immune response, and enzyme binding were enriched in macrophages. …”
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The protein tyrosine phosphatase, nonreceptor type 22-1858C->T (rs2476601) polymorphism is not a genetic risk factor for systemic lupus erythematosus in Indian Tamils by Panneer Devaraju, Reena Gulati, Durga Prasanna Misra, Vir Singh Negi

“…Background: Systemic lupus erythematosus (SLE), a systemic autoimmune disease, occurs due to disruption of immune homeostasis against self-antigens. The etiology of SLE is complex and multiple genetic factors contribute to disease susceptibility and clinical phenotypes. …”
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Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds. by Shafia Tehseen Gul, Muhammad Zergham Tahir, Latif Ahmad, Aisha Khatoon, Muhammad Kashif Saleemi, Farid Shokry Ataya, Riaz Hussain, Bakhtawar Maqbool, Dalia Fouad, Ahrar Khan

“…So, this study was designed to evaluate the toxico-pathological effects of fipronil on the immune system of poultry birds. One hundred a-day-old chicks were purchased from a local hatchery, and standard housing conditions were provided from brooding till the end of the trail. …”
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Biomarkers in Nasopharyngeal Carcinoma (NPC): Clinical relevance and prognostic potential by Madhan Krishnan, Shyamaladevi Babu

“…However, ongoing research has identified additional biomarkers, such as circulating tumor cells (CTCs), microRNAs, and immune-related molecules that provide further prognostic insights. …”
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