IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2 by Rong Xu, Hong-Fan Sun, David W. Williams, Adam V. Jones, Ali Al-Hussaini, Bing Song, Xiao-Qing Wei

“…Resident macrophages exhibit phenotypic plasticity and may transform into inflammatory M1 macrophages for immunity or anti-inflammatory M2 macrophages for tissue repair. …”
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Implication of Cytotoxic Helicobacter pylori Infection in Autoimmune Diabetes by Alessandro P. Delitala, Giovanni M. Pes, Hoda M. Malaty, Gavino Pisanu, Giuseppe Delitala, Maria P. Dore

“…Although H. pylori seroprevalence was similar in LADA, T1D, and T2D, anti-CagA positivity was significantly increased among patients with autoimmune diabetes, suggesting that more virulent H. pylori strains might be a trigger for immune mechanisms involved in their pathogenesis.…”
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FutureMS cohort profile: a Scottish multicentre inception cohort study of relapsing-remitting multiple sclerosis by David Hunt, Siddharthan Chandran, Peter Connick, Peter Foley, Patrick K A Kearns, Sergio E Baranzini, Adam D Waldman, Sarah J Martin, Elizabeth Freyer, F J Carod-Artal, Lee Murphy, Amy Stenson, Jessie Chang, Rozanna Meijboom, Elizabeth N York, Yingdi Chen, Christine Weaver, Katarzyna Hafezi, Stacey Thomson, Adil Harroud, Margaret McLeod, Jonathon O'Riordan, Niall J J MacDougall

“…Purpose Multiple sclerosis (MS) is an immune-mediated, neuroinflammatory disease of the central nervous system and in industrialised countries is the most common cause of progressive neurological disability in working age persons. …”
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Ficolin B in Diabetic Kidney Disease in a Mouse Model of Type 1 Diabetes by Charlotte Berg Holt, Jakob Appel Østergaard, Esben Axelgaard, Gitte Krogh Nielsen, Yuichi Endo, Steffen Thiel, Troels Krarup Hansen

“…Background. The innate immune system may have adverse effects in diabetes and cardiovascular disease. …”
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A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy by Ling Wang, Yuzhong Zhang, Shenglin Geng, Lan Ma, Yiran Wang, Dongxu Han, Guojuan Fan, Weifen Zhang, Weifen Zhang, Weifen Zhang, Yanna Lv, Jinlong Ma, Jinlong Ma, Jinlong Ma

“…Importantly, it resulted in improved skin lesion scores, scratching behavior, eosinophil infiltration, swelling and inflammation levels, immune homeostasis, and histopathological changes in rats with acute eczema. …”
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The Pathogenesis of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome: A Review of Current Research by Barbara Kraszewska-Głomba, Agnieszka Matkowska-Kocjan, Leszek Szenborn

“…Immunological mechanisms of PFAPA involve an abnormal, IL-1β dependent innate immune response to an environmental trigger, which leads to Th1-driven inflammation expressed by recruitment of T-cells to the periphery.…”
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Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration by Susanne W. Bruun, Knud Josefsen, Julia T. Tanassi, Aleš Marek, Martin H. F. Pedersen, Ulrik Sidenius, Martin Haupt-Jorgensen, Julie C. Antvorskov, Jesper Larsen, Niels H. Heegaard, Karsten Buschard

“…If present in pancreas, gliadin could interact directly with the immune system and the beta cells to initiate diabetes development. …”
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Establishment of a method for detecting complement C3d-sensitized platelets by LI Hongyang, YU Hongmei, WANG Changmin, LIU Tiemei

“…[Conclusion] A microcolumn gel immunoagglutination inhibition test was established to detect whether platelets are sensitized by complement C3d, which aids in the auxiliary diagnosis of complement-related immune diseases involving platelets.…”
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The Anti-Inflammatory Cytokine, Interleukin-10, Inhibits Inflammatory Mediators in Human Epithelial Cells and Mouse Macrophages Exposed to Live and UV-Inactivated Chlamydia trachom... by Abebayehu N. Yilma, Shree R. Singh, Stacie J. Fairley, Murtada A. Taha, Vida A. Dennis

“…Here we hypothesized that IL-10, with anti-inflammatory properties, will inhibit inflammatory mediators that are produced by innate immune cells exposed to C. trachomatis. We used human epithelial (HeLa) cells and mouse J774 macrophages as target cells along with live and UV-inactivated C. trachomatis mouse pneumonitis (MoPn) as stimulants. …”
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Correlation of Interleukin-17-Producing Effector Memory T Cells and CD4+CD25+Foxp3 Regulatory T Cells with the Phosphate Levels in Chronic Hemodialysis Patients by Cheng-Lin Lang, Min-Hui Wang, Kuan-Yu Hung, Sung-Hao Hsu, Chih-Kang Chiang, Kuo-Cheng Lu

“…Interleukin-17-producing CD4+ effector memory T (Th17) cells and CD4+CD25+Foxp3 regulatory T (Treg) cells both play critical roles in immune activation and inflammation. We investigated the relationship between the Treg and Th17 cells and the phosphate level in chronic HD patients. …”
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Impacts of noise and interference on the bit error rate of the FBMC-OQAM modulation scheme in 5G systems by A. Androon, O. V. Tikhonova

“…The work sets out to evaluate the noise immunity of the signal modulation method in 5G networks using a filter bank multicarrier with offset quadrature amplitude modulation (FBMC-OQAM) and to analyze the bit error rate (BER).Methods. …”
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Novel Polymorphism in a Promoter of MBL2 Gene Result in Lower MBL Expression in Chronic Infection Caused by HCV by Paywast Jamal Jalal

“…The Pathogen Recognition Receptors (PRRs) is an active protein in the immune system. The PRRs that secreted in the liver and we addressed were L-ficolin, MBL and H-ficolin. …”
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Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy. by Sidra Zafar, Yuhe Bai, Syed Aun Muhammad, Jinlei Guo, Haris Khurram, Saba Zafar, Iraj Muqaddas, Rehan Sadiq Shaikh, Baogang Bai

“…In this study, machine learning and MD simulation-based approach are effectively used to design T-cell epitopes that aid the immune system against liver cancer. Antigenicity, molecular weight, subcellular localization and expression site predictions were used to shortlist liver cancer associated proteins including AMBP, CFB, CDHR5, VTN, APOBR, AFP, SERPINA1 and APOE. …”
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Effects of Lysozyme, Proteinase K, and Cephalosporins on Biofilm Formation by Clinical Isolates of Pseudomonas aeruginosa by Mohamed Eladawy, Mohammed El-Mowafy, Mohamed Mohamed Adel El-Sokkary, Rasha Barwa

“…Pseudomonas aeruginosa is an opportunistic pathogen that can form biofilms, which confer resistance to immune clearance and antibacterial treatment. Therefore, effective strategies to prevent biofilm formation are warranted. …”
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From Bench to Bedside to Bug: An Update of Clinically Relevant Advances in the Care of Persons with Helicobacter pylori Associated Diseases by N Chiba, ABR Thomson, P Sinclair

“…The number of H pylori-associated gastroduodenal diseases grows to include possible liver, vascular, immune and skin conditions.…”
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HIV, the gut microbiome and clinical outcomes, a systematic review. by Rachel Mac Cann, Ellen Newman, Declan Devane, Caroline Sabin, Aoife G Cotter, Alan Landay, Paul W O'Toole, Patrick W Mallon

“…However, this population is now experiencing accelerated age-related comorbidities, contributed to by chronic immune activation and inflammation, with dysbiosis of the gut microbiome also implicated.…”
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HIV-Infected Individuals Do Not Present Significant Differences regarding Periodontal Status: A Systematic Review and Meta-Analysis by Lucas Ribeiro Teixeira, Diana Estefania Ramos Peña, Leticia Rodrigues de Castro, Márcia dos Santos, Maria da Conceição Pereira Saraiva, Fernando Chahud, Bruno Pozzetto, Alan Grupioni Lourenço, Ana Carolina Fragoso Motta

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Perinatal Outcome of Fetal Echogenic Bowel: A Single-Center Retrospective Cohort Study by Hidayet Sal, Erhan Huseyin Comert, Yasin Semih Ekici, Turhan Aran

“…Demographic questionnaire and face to face interview were used to obtain data including immune system diseases and respiratory system pathologies in infants. …”
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Effect of Laughter Therapy on the Psychological and Physiological State of a Person by Liana Spytska

“… The study of laughter therapy can help people better understand how laughter can reduce stress, boost mood, and improve the immune system and overall physical condition, so this topic is quite relevant and necessary in the modern world. …”
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The Mechanisms of Systemic Inflammatory and Immunosuppressive Acute-on-Chronic Liver Failure and Application Prospect of Single-Cell Sequencing by Kai Kou, Xiaodong Sun, Guangyao Tian, Yao Zhi, Zhongqi Fan, Guoyue Lv

“…Liver inflammation begins when innate immune cells (such as Kupffer cells (KCs)) are activated by binding of pathogen-associated molecular patterns (PAMPs) from pathogenic microorganisms or damage-associated molecular patterns (DAMPs) of host origin to their pattern recognition receptors (PRRs). …”
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