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7781
Synergistic effects of alginate oligosaccharide and cyanidin-3-O-glucoside on the amelioration of intestinal barrier function in mice
Published 2023-11-01“…Interestingly, the secretion of immunoglobulin A and immune-related cytokines were approximately doubled by the AOS + C3G mixture. …”
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7782
Genome-Wide DNA Methylation in Mixed Ancestry Individuals with Diabetes and Prediabetes from South Africa
Published 2016-01-01“…Our data shows that genes related to the immune system, signal transduction, glucose transport, and pancreas development have altered DNA methylation in subjects with prediabetes and diabetes. …”
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7783
Establishment of Gill-Derived Primary Cell Cultures from Largemouth Bass (<i>Micropterus salmoides</i>) as an Alternative Platform for Studying Host–Virus Interactions
Published 2025-01-01“…These findings highlight the utility of the largemouth bass gill-derived primary cell culture as an alternative in vitro system for investigating MSRV pathogenesis and host immune responses, which serves as a stepping stone for improved antiviral strategies in largemouth bass aquaculture.…”
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7784
Targeting Shp2 as a therapeutic strategy for neurodegenerative diseases
Published 2025-01-01“…Shp2 is closely related to NDs-related pathogenic factors such as oxidative stress, mitochondrial dysfunction, excitatory toxicity, immune inflammation, apoptosis, and autophagy. Its bidirectional effects interfere with these pathogenic factors, making it a core component of the feedback and crosstalk network between multiple signaling pathways. …”
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7785
Effects and Impact of Selenium on Human Health, A Review
Published 2024-12-01“…Selenium boasts numerous biological functions, including antioxidant properties, immune system enhancement, thyroid function regulation, anti-cancer effects, cardiovascular protection, reproductive capability improvement, and anti-inflammatory activity. …”
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7786
Liver macrophage-derived exosomal miRNA-342-3p promotes liver fibrosis by inhibiting HPCAL1 in stellate cells
Published 2025-02-01“…Abstract Background The progression of liver fibrosis involves complex interactions between hepatic stellate cells (HSCs) and multiple immune cells in the liver, including macrophages. …”
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7787
Obesity, dietary interventions and microbiome alterations in the development and progression of prostate cancer
Published 2025-01-01“…To further our understanding, future human studies in prostate cancer should investigate microbiome changes and incorporate an assessment of microbiome-derived metabolites and cellular/immune changes in the TME.…”
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7788
A ketogenic diet regulates microglial activation to treat drug addiction
Published 2025-01-01“…Many studies have shown that psychoactive substances may act directly on immune cells, altering their function and inducing the production of various inflammatory mediators. …”
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7789
Unveiling the nanoworld of antimicrobial resistance: integrating nature and nanotechnology
Published 2025-01-01“…In addition to increasing their effectiveness and boosting the immune system, this synergistic approach provides a safer and more effective method of tackling future bacterial infections.…”
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7790
Anti-PD-1 exacerbates bleomycin-induced lung injury in mice via Caspase-3/GSDME-mediated pyroptosis
Published 2025-01-01“…Abstract Immune checkpoint inhibitors (ICIs) have significant therapeutic effects but can also cause fatal lung injury. …”
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7791
Quality of Life Patients HIV Based on Characteristic, Duration of Diagnosis, and Types Antiretroviral (ARV)
Published 2024-04-01“…Human Immunodeficiency Virus (HIV) is a retrovirus that attacks the body's immune system, leading to an increase in morbidity and mortality rates in Indonesia. …”
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7792
Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration
Published 2021-01-01“…However, recent evidence has shown that the stem cell secretome plays an important role in biological processes such as the immune response, inflammation regulation, and drug delivery. …”
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7793
Chronic-Alcohol-Abuse-Induced Oxidative Stress in the Development of Acute Respiratory Distress Syndrome
Published 2012-01-01“…The aims of this paper are to address the mechanisms for alcohol-induced GSH depletion and oxidation and the subsequent effects in alveolar barrier integrity, modulation of the immune response, and apoptosis.…”
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7794
Targeting glycolytic reprogramming by tsRNA-0032 for treating pathological lymphangiogenesis
Published 2025-01-01“…Abstract Lymphangiogenesis is vital for tissue fluid homeostasis, immune function, and lipid absorption. Abnormal lymphangiogenesis has been implicated in several diseases such as cancers, inflammatory, and autoimmune diseases. …”
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7795
Nanopore sequencing of protozoa: Decoding biological information on a string of biochemical molecules into human-readable signals
Published 2025-01-01“…Specifically, we sequenced blood and fecal samples from mice infected with Trypanosoma brucei, a unicellular protozoan known for its hypervariable and dynamic regions that help it evade host immunity. Such characteristics are also prevalent in other host-dependent parasites, such as bacteriophages. …”
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7796
The Impact of Autophagy on Cell Death Modalities
Published 2014-01-01“…., apoptosis), inflammation, and adaptive immune mechanisms and thereby influence disease pathogenesis. …”
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7797
Proinflammatory Effects of Diesel Exhaust Nanoparticles on Scleroderma Skin Cells
Published 2014-01-01“…We aimed to verify whether environmental pollution from diesel engine exhaust nanoparticulate (DEP) of actually operating vehicles could play a role in the development of a rare immune-mediated disease, systemic sclerosis (SSc), in which the pathogenetic role of environment has been highlighted. …”
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7798
Volume-regulated anion channels conduct ATP in undifferentiated mammary cells and promote tumorigenesis in xenograft nude mouse
Published 2025-01-01“…The high interstitial ATP concentration in the cancer microenvironment is a major source of adenosine, which acts as a strong immune suppressor. However, the source of ATP release has not been elucidated. …”
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7799
Vaccinating Adult Patients with Cirrhosis: Trends over a Decade in the United States
Published 2016-01-01“…The progression of chronic liver disease to cirrhosis involves both innate and adaptive immune system dysfunction resulting in increased risk of infectious complications. …”
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7800
Comprehensive analysis reveals the tumor suppressor role of macrophage signature gene FCER1G in hepatocellular carcinoma
Published 2025-02-01“…Additionally, patients in the high-risk group exhibited elevated tumor stemness scores, although no significant differences were observed in microsatellite instability (MSI) and tumor mutational burden (TMB) scores. Immune-related analyses revealed that FCER1G expression was downregulated in HCC and was associated with key pathways such as apoptosis and ferroptosis. …”
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