Nucleoside analogues in treatment of liver cirrhosis as an outcome of chronic hepatitis B by I. G. Bakulin

“…Rates of progression of persistent HBV infection to liver cirrhosis stage depend on several factors – spectrum of viral markers, immune status of the patient, his/her age, gender, genetic predisposition, etc. …”
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Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment by Tian Z, Wang X, Chen S, Guo Z, Di J, Xiang C

“…Zui Tian,* Xudong Wang,* Shuai Chen,* Zijian Guo, Jingkai Di, Chuan Xiang Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuan Xiang, Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China, Email chuanxiang@sxmu.edu.cnAbstract: Macrophage immunotherapy is an emerging therapeutic approach designed for modulating the immune response to alleviate disease symptoms. The balance between pro-inflammatory and anti-inflammatory macrophages plays a pivotal role in the progression of inflammatory diseases. …”
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The Effect of Anthelmintic Treatment on Coccidia Oocyst Shedding in a Wild Mammal Host with Intermittent Cestode Infection by Radovan Václav, Jana Blažeková

“…Also, the marmot’s response towards coccidia infection appears optimal only under no helminth infection when the host immune response towards coccidia would not be compromised, thereby pointing to the importance of regular intestinal helminth elimination by marmots just before hibernation.…”
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Candida Albicans Candidalysin ECE1 Gene − A Potent Virulence Factor for Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders by Mani B. Subramani, Krishnan Mahalakshmi, Bharathy Jaya, Sankar Leena Sankari, Venkatesan N. Kumar

“…This toxin is most important for epithelial immune activation, invasiveness and infection of the oral mucosa. …”
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Improvement of bovine tuberculosis diagnosis by M. O. Baratov

“…The highest antibody titers (1:3000 and 1:4000) were received in hyperimmune sera of rabbits immunized with Mycobacterium bovis using a homologous diagnosticum. …”
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Bap, a biofilm matrix protein of Staphylococcus aureus prevents cellular internalization through binding to GP96 host receptor. by Jaione Valle, Cristina Latasa, Carmen Gil, Alejandro Toledo-Arana, Cristina Solano, José R Penadés, Iñigo Lasa

“…The biofilm matrix, composed of exopolysaccharides, proteins, nucleic acids and lipids, plays a well-known role as a defence structure, protecting bacteria from the host immune system and antimicrobial therapy. However, little is known about its responsibility in the interaction of biofilm cells with host tissues. …”
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Hepatic transcript profiling in beef cattle: Effects of rumen-protected niacin supplementation. by Gastón F Alfaro, Valentino Palombo, Mariasilvia D'Andrea, Wenqi Cao, Yue Zhang, Jonathan Beever, Russell B Muntifering, Wilmer J Pacheco, Soren P Rodning, Xu Wang, Sonia J Moisá

“…Consequently, we wanted to assess the known role of niacin in the physiological processes of vasodilation, detoxification, and immune function in beef hepatic tissue. Normal weaned calves (~8 months old) were provided either a control diet or a diet supplemented with rumen-protected niacin (6 g/hd/d) for a 30-day period, followed by a liver biopsy. …”
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Gastric cancer – Clinical aspects by J. Bornschein

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Vertebrate TNF Superfamily: Evolution and Functional Insights by Ignacio Marín

“…This evolutionary model provides a framework for exploring functional data, showing that the descendants of different ancestral genes have acquired distinct roles, most prominently in the innate and adaptive immune systems, which led to a species-specific refinement of which TNFSF genes were conserved or lost. …”
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Is Thymoglobulin or Rituximab the Cause of This Serum Sickness? A Case Report of Serum Sickness Dilemma and Literature Review by Amarpreet Sandhu, Antonia Harford, Pooja Singh, Eduardo Alas

“…Serum sickness is an immune-complex-mediated systemic illness that can occur after treatment with monoclonal or polyclonal antibodies such as Rituxan (Rituximab) or antithymocyte globulin (Thymoglobulin), respectively. …”
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Vibrio parahaemolyticus: Exploring its Incidence in Malaysia and the Potential of Streptomyces sp. as an Anti-Vibrio Agent by Ke-Yan Loo, Loh Teng-Hern Tan, Jodi Woan-Fei Law, Priyia Pusparajah, Sunny Hei Wong, Kok-Gan Chan, Learn-Han Lee, Vengadesh Letchumanan

“…The bioactive compounds produced by Streptomyces sp. have been proven to have microbiota-modulating and stimulatory effects on the host, enhancing immunity and providing protective effects against V. parahaemolyticus infections. …”
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Hyperglycaemia after dolutegravir-based antiretroviral treatment in people living with human immunodeficiency virus: A case series by Keerthana Sagadevan, Pilla S. Surya Durga Devi, Katikatala Swaroopa, P. Sathish Sreenivas, R. Srinivasa Rao

“…All five patients who were living with HIV either started or switched to ART with a tenofovir, lamivudine and DTG (TLD) regimen based on the latest guidelines for HIV treatment by the National Acquired Immune Deficiency Syndrome Control Organization (NACO). …”
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The Role of IL-33 in Gut Mucosal Inflammation by Luca Pastorelli, Carlo De Salvo, Maurizio Vecchi, Theresa T. Pizarro

“…Interleukin (IL)-33 is a recently identified cytokine belonging to the IL-1 family that is widely expressed throughout the body and has the ability to induce Th2 immune responses. In addition, IL-33 plays a key role in promoting host defenses against parasites through the expansion of a novel population of innate lymphoid cells. …”
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Role of Farnesoid X Receptor in the Pathogenesis of Respiratory Diseases by Jin-nan Wu, Jian-rong Chen, Jin-liang Chen

“…For example, FXR can regulate the tumor microenvironment by regulating the balance of inflammatory and immune responses in the body to promote the occurrence and development of non-small-cell lung cancer (NSCLC), thereby being considered a potential target for immunotherapy of NSCLC. …”
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Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases by Punita Kalia, Rohini Ravindran Nair, Suresh Singh Yadav

“…Our observations showed a significant correlation of exportins expression with clinical parameters, used to predict a patient's prognosis in general, such as advancing tumor stage, overall/relapse-free survival, and immune cell infiltrations. Mutation analysis showed the presence of amplifications, missense mutations in XPO2 and XPO4, and deep deletions in XPO7 genes contributing to disease progression and patients survival. …”
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Perception of peacekeeping activities in Africa by the local population (on the example of Mali) by S. A. Bokeriya, A. R. Andronova

“…The research for this attitude are both objective (for example, the privileges and immunity enjoyed by peacekeepers on the territory of Mali; participation of peacekeepers in corruption schemes; their unauthorized use of force) and subjective (MINUSMA’s ignorance of local problems and of the mission’s mandate).…”
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Polyarticular Septic Arthritis Caused by Haemophilus Influenzae in an Asplenic Patient: A Case Report by Roberto Desarden, Roya Caloia

“…Introduction: Prevalence of serious infections from Haemophilus influenzae has diminished over the last few decades because of immunizations against the most virulent serotype. However, over the last few years a handful of septic arthritis cases secondary to H influenzae have been documented. …”
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A Rare Cause of Ascites-Disseminated TB with Peritonitis in a Middle-Aged Female by Sahathevan Vithoosan, Ponnudurai Shanjeeban, Joseph Philip Anpalahan, Paramarajan Piranavan, Harindra Karunatilake, Ananda Jayanaga

“…Disseminated tuberculosis (TB) has been increasingly recognized in adults in the recent times due to increased prevalence of immune suppression. Here we describe a case of 47-year-old female who presented with disproportionate ascites where the diagnosis of disseminated TB was delayed. …”
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Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1G93A Transgenic Mice by MuDan Cai, Eun Jin Yang

“…These results suggest that GSS could be used for improving the immune system and increasing the life quality of patients with ALS.…”
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PANoptosis in intestinal epithelium: its significance in inflammatory bowel disease and a potential novel therapeutic target for natural products by Chuanxiang Zhao, Shan Lin

“…The intestinal epithelium, beyond its role in absorption and digestion, serves as a critical protective mechanical barrier that delineates the luminal contents and the gut microbiota from the lamina propria within resident mucosal immune cells to maintain intestinal homeostasis. The barrier is manifested as a contiguous monolayer of specialized intestinal epithelial cells (IEC), interconnected through tight junctions (TJs). …”
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