Cavitating Mesenteric Lymph Node Syndrome in Association with Coeliac Disease and Enteropathy Associated T-Cell Lymphoma: A Case Report and Review of the Literature by Olivia M. B. McBride, Richard J. E. Skipworth, Derek Leitch, Satheesh Yalamarthi

“…Cavitating mesenteric lymph node syndrome (CMLNS) is a rare and poorly understood complication of coeliac disease (CD), with only 37 cases reported in the literature. CD is an immune-mediated enteropathy, with alterations seen in the small bowel architecture on exposure to ingested gluten. …”
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Clinical Significance and Characterization of AZT-Resistant Strains of HIV-1 by Mark A Wainberg, Ronald Rooke, Michel Tremblay, XuGuang Li, Michael A Parniak, Qing Gao, Xiao-Jian Yao, Chris Tsoukas, JSG Montaner, M Fanning, J Ruedy

“…In certain instances, such drug-resistant viral isolates have been obtained from patients with clinical acquired immune deficiency syndrome (AIDS), while in others, isolation of drug-resistant strains has been achieved in the case of HIV seropositive, asymptomatic subjects. …”
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The “necessary death” of the Grand Duke: on the question of the causes and circumstances of the death of Yaroslav Vsevolodovich in the autumn of 1246 by Vorotyntsev L.V., Galimov T.R.

“…This conclusion is drawn considering the absence of qualified medical care, weakened immunity, and the advanced age of the ruler of Northeastern Russia.…”
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Single-cell transcriptome atlas of male mouse pituitary across postnatal life highlighting its stem cell landscape by Silke De Vriendt, Emma Laporte, Berkehür Abaylı, Julie Hoekx, Florian Hermans, Diether Lambrechts, Hugo Vankelecom

“…Our investigation substantiated changes in stem cell dynamics during aging, reinforcing the inflammatory/immune nature in elderly pituitary and stem cells. …”
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Advances and Challenges in Islet Transplantation: Islet Procurement Rates and Lessons Learned from Suboptimal Islet Transplantation by Annette Plesner, C. Bruce Verchere

“…To facilitate the engraftment of more robust islets suitable for combating the challenging isolation period and proinflammatory transplantation milieu, numerous approaches have been employed to prevent beta-cell dysfunction and death including immune modulation, prevention of apoptosis and hypoxia, as well as stimulation of growth factors, angiogenesis, and reinnervation. …”
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A fractal–fractional order modeling approach to understanding stem cell-chemotherapy combinations for cancer by Esam Y. Salah, Bhausaheb Sontakke, Ahmed A. Hamoud, Homan. Emadifar, Atul Kumar

“…Also, the result of the numerical simulation and graphic for the concentration of cells over time indicate the effects of the therapies on the decay rate of tumor cells and the growth rate of effector cells to modify the cancer patient’s immune system. It is worth noting that we simulated all the model components with different fractional orders, confirming the effect of stem cell therapy and chemotherapy on the cells and the decay of cancer cells.…”
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Endogenous nitroso compounds (NOC) from dietary source: Plausible promoters of oral carcinogenesis in non-smokers and non-alcoholics by Rajashree Padmanaban, Ramya Ramadoss, Rajkumar Krishnan

“…Discussion: The intricate interplay between endogenous nitroso compounds, oral microbiota, and the host's immune response presents a complex landscape in understanding the promotion of oral carcinogenesis in non-smokers and non-alcoholics. …”
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Fused extracellular vesicles from M2 macrophages and human umbilical cord mesenchymal stem cells for the targeted regulation of macrophage pyroptosis in periprosthetic osteolysis by Qimeng Liu, Tianliang Ma, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie

“…These fEV boast the distinctive capability for targeted transport and immune evasion, collectively enhancing the anti‐pyroptosis effect of the therapeutic extracellular vesicles. …”
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Potential Role of the Inflammasome-Derived Inflammatory Cytokines in Pulmonary Fibrosis by Rupa Biswas, Melisa Bunderson-Schelvan, Andrij Holian

“…The inflammasome is a multiprotein complex that is an important component of both the innate and adaptive immune systems. Activation of proinflammatory cytokines following inflammasome assembly, such as IL-1β and IL-18, has been associated with development of PF. …”
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The Rise of Pluripotent Stem Cell-Derived Glia Models of Neuroinflammation by Srishti Kala, Andrew G. Strutz, Moriah E. Katt

“…It encompasses a phenotype shift to a proinflammatory state, the release of cytokines, the recruitment of peripheral immune cells, and a wide variety of other processes. …”
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Analysis and Design of FeFET Synapse With Stacked-Nanosheet Architecture Considering Cycle-to-Cycle Variations for Neuromorphic Applications by Heng Li Lin, Pin Su

“…For a stacked-nanosheet FeFET synapse with an area ratio effect, the G_DS response can be further engineered by varying the tier number. In addition, the immunity to cycle-to-cycle variations and the noise margin for each state in the G_DS response can also be improved by increasing the number of tiers. …”
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Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases by Yunlong Ma, Dingping Jiang, Jingjing Li, Gongwei Zheng, Yao Deng, Xuanxuan Gou, Shuaishuai Gao, Cheng Chen, Yijun Zhou, Yaru Zhang, Chunyu Deng, Yinghao Yao, Haijun Han, Jianzhong Su

“…Functionally, excitatory neuron-specific regulons were involved in axon guidance and synaptic activity, while microglia-specific regulons were associated with immune response and cell activation. In sum, these findings underscore the genetic link between psychiatric disorders and ocular diseases.…”
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Human T follicular helper cells and their impact on IgE and IgG4 production across allergy, malignancy, and IgG4-related disease by Mitsuhiro Akiyama, Waleed Alshehri, Sho Ishigaki, Koichi Saito, Yuko Kaneko

“…Their critical role in diseases such as allergy, malignancy, and IgG4-related disease highlights their profound impact on balancing inflammation and immune tolerance. Our current review provides the molecular characteristics of human Tfh cells, the differentiation pathways of Tfh subsets, mechanisms by which Tfh subsets induce IgE and IgG4 production, and their clinical implications in allergy, malignancy, and IgG4-related disease.…”
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RevCAR-mediated T-cell response against PD-L1-expressing cells turns suppression into activation by Eugenia Crespo, Liliana R. Loureiro, Antonia Stammberger, Lydia Hoffmann, Nicole Berndt, Anja Hoffmann, Claudia Dagostino, Karla E. G. Soto, Luise Rupp, Claudia Arndt, Martin Schneider, Claudia R. Ball, Michael Bachmann, Marc Schmitz, Anja Feldmann

“…While our modular RevCAR system enhances the safety and controllability of CAR T-cell therapy, effectively targeting solid tumors remains difficult. Since PD-L1 is an immune checkpoint frequently upregulated by cancer cells and their microenvironment, it is a relevant target for solid tumors. …”
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Role of extracellular vesicles in the pathogenesis of mosquito-borne flaviviruses that impact public health by Pedro Pablo Martínez-Rojas, Verónica Monroy-Martínez, Blanca H. Ruiz-Ordaz

“…This review focuses on the roles of extracellular vesicles in the pathogenesis of mosquito-borne flavivirus diseases: how they contribute to viral cycle completion, cell-to-cell transmission, and cellular responses such as inflammation, immune suppression, and evasion, as well as their potential use as biomarkers or therapeutics (antiviral or vaccines). …”
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Metabolic Pathways Associated with Kimchi, a Traditional Korean Food, Based on Modeling of Published Data by Ga Hee Shin, Byeong-Chul Kang, Dai Ja Jang

“…The various unique microorganisms and bioactive components in kimchi show antioxidant activity and have been associated with an enhanced immune response, as well as anti-cancer and anti-diabetic effects. …”
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Choice of Unmanipulated T Cell Replete Graft for Haploidentical Stem Cell Transplant and Posttransplant Cyclophosphamide in Hematologic Malignancies in Adults: Peripheral Blood or... by Shatha Farhan, Edward Peres, Nalini Janakiraman

“…However, there are still lots of unanswered questions, like the effect of use of bone marrow versus peripheral blood as the source of stem cells on graft-versus-host disease, graft versus tumor, overall survival, immune reconstitution, and quality of life. Here we review the available publications on bone marrow and peripheral blood experience in the haploidentical SCT setting.…”
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Virulence of Bacteria Causing Mastitis in Dairy Cows: A Literature Review by Xiaofang Tong, Herman W. Barkema, Diego B. Nobrega, Chuang Xu, Bo Han, Chenyibo Zhang, Jingyue Yang, Xiaoping Li, Jian Gao

“…To bridge these gaps, this manuscript reviews and compiles research on the virulence factors of these pathogens, focusing on their roles in mammary tissue infection, immune evasion, adherence to mammary epithelial cells, and invasion and colonization of the mammary gland. …”
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In vivo trafficking of cancer-derived exosomes and their role in metastasis by Shih-Yen Wei, Sarah E. Shelton, Ying-Chieh Chen, Ke Huang

“…This process is driven by a combination of biological processes including invasion, intravasation, circulation, extravasation, and colonization of distant organs, among which cancer cell-derived exosomes facilitate metastasis through their enriched oncogenic miRNAs and lncRNAs to enhance cancer cell migration and invasion, promote epithelial-mesenchymal transition in recipient cells, help cancer cells evade immune detection, and alter the microenvironment to promote the formation of a pre-metastatic niche. …”
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Illness Representations and Treatment Adherence in Patients with Acute Leukemia and Lymphoma by L.V. Esina, D.E. Vybornykh, E.I. Rasskazova, E.G. Gemdzhian, E.E. Zvonkov, I.A. Lukyanova, T.N. Moiseeva, A.U. Magomedova

“…In acute leukemia, the targets of psychological work aimed at preventing reduced adherence to treatment are patients' perceptions of the psychological causes of the disease and their belief that healthy habits are not important for maintaining health, while in patients with lymphomas &mdash; uncertainty that immune problems could provoke the disease.</p>…”
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