Provocative tests of anal sphincter function correlate with symptoms and subtypes of faecal incontinence by John McLaughlin, Dipesh H Vasant, Asbjørn Mohr Drewes, Abhiram Sharma, Matthew Davenport, Edward Kiff, Karen Telford, Alexander O'Connor, Donghua Liao, Niels Klarskov

“…However, provocative tests (functional lumen imaging probe (FLIP) and anal acoustic reflectometry (AAR)) have been proposed as alternatives. …”
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γ-Aminobutyric Acid (GABA) Metabolic Bypass Plays a Crucial Role in Stress Tolerance and Biofilm Formation in <i>C. sakazakii</i> ATCC 29544 by Jiangchao Wu, Yigang Yu, Fengsong Liu, Yifang Cao, Jiahao Ren, Yiting Fan, Xinglong Xiao

“…The deletion of <i>gabT</i> resulted in enhanced GABA accumulation under different stress conditions, improving the bacterium’s tolerance to desiccation, osmotic pressure, and acid treatment. SEM images revealed that under identical stress conditions, the <i>gabT</i> knockout strain exhibited less cellular damage compared to the wild-type strain. …”
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Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes by Jody Dushay, Eva S. Rickers, Enya Wang, Jessica Gilman, Ying Zhang, Ron Blankstein, Ernest V. Gervino, Michael Jerosch‐Herold, Aristidis Veves

“…Methods Older individuals (aged≥65 years) underwent biochemical and tissue inflammatory phenotyping, cardiopulmonary exercise testing, cardiovascular magnetic resonance imaging, and vascular reactivity testing. Correlation and regression analyses determined the effects of systemic inflammation, older age, and sex on cardiovascular health, stratified by T2D status. …”
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Otologic Manifestations in Patients with Achondroplasia: A Multicenter Study by Dohee Kim, Joonsik Yoon, Myung-Whan Suh, Jun Ho Lee, Moo Kyun Park

“…Demographic and clinical characteristics, including audiometric findings, imaging studies, treatment modalities, and outcomes, were analyzed. …”
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Evaluation of Wisconsin and CaPTHUS Indices Usefulness for Predicting Monoglandular and Multiglandular Disease in Patients with Primary Hyperparathyroidism through the Analysis of... by Loredana De Pasquale, Eleonora Lori, Antonio Mario Bulfamante, Giovanni Felisati, Luca Castellani, Alberto Maria Saibene

“…Both patients for whom preoperative imaging agreed with the localization of a single diseased parathyroid and those with only ultrasound or scintigraphy positive for parathyroid localization underwent Mini-Invasive Video-assisted parathyroidectomy. …”
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Executive function, limbic circuit dynamics and repetitive and restricted behaviors in children with autism spectrum disorder by Xiangyu Zheng, Xinyue Wang, Ruochen Song, Junbin Tian, Li Yang

“…Since the orbitofrontal cortex (OFC) plays a role in both EF and RRBs, its functional connectivity dynamics could offer valuable insights into this relationship.MethodsThis study analyzed data from the Autism Brain Imaging Data Exchange (ABIDE) II database to explore brain function in 93 boys with ASD and 110 typically developing (TD) boys. …”
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MAMMOTH-Subaru. II. Diverse Populations of Circumgalactic Lyα Nebulae at Cosmic Noon by Mingyu Li, Haibin Zhang, Zheng Cai, Yongming Liang, Nobunari Kashikawa, Ke Ma, Xiaohui Fan, J. Xavier Prochaska, Bjorn H. C. Emonts, Xin Wang, Yunjing Wu, Shiwu Zhang, Qiong Li, Sean D. Johnson, Minghao Yue, Fabrizio Arrigoni Battaia, Sebastiano Cantalupo, Joseph F. Hennawi, Satoshi Kikuta, Yuanhang Ning, Masami Ouchi, Rhythm Shimakawa, Ben Wang, Weichen Wang, Zheng Zheng, Zhen-Ya Zheng

“…This work investigates Ly α nebulae from deep imaging of ∼12 deg ^2 sky, targeted by the MAMMOTH-Subaru survey. …”
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Increased global posterior tibial slope is significantly associated with higher ACL graft signal intensity on 2-Year postoperative MRI after primary ACL reconstruction using hamstr... by Zhi-yu Zhang, Le-jin Hong, Wen-bin Bai, Jia-yi Shao, Yi-tian Gao, Xiao-yue Fu, Jian-quan Wang, Cheng Wang

“…Patients were followed up and scheduled for a 2-year postoperative magnetic resonance imaging (MRI) scan at our institute. Concomitant injuries were confirmed by arthroscopy. …”
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Diagnosis of Malignant Endometrial Lesions from Ultrasound Radiomics Features and Clinical Variables Using Machine Learning Methods by Shanshan Li, Jiali Wang, Li Zhou, Hui Wang, Xiangyu Wang, Jian Hu, Qingxiu Ai

“…We sketched the region of interest (ROI) of the abnormalities on the ultrasound images. Then, the radiomics features were extracted. …”
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Cardiac resynchronization therapy via left bundle branch pacing in heart failure with complete left bundle branch block: is the defibrillator needed? by Dandan Yang, Dandan Yang, Qunchao Ma, Qunchao Ma, Hong Zhu, Lihua Wang, Meixiang Xiang, Meixiang Xiang, Jian’an Wang, Jian’an Wang, Jian’an Wang, Jian’an Wang, Xiaohong Pan, Xiaohong Pan

“…Patients with ischemic cardiomyopathy, left ventricular noncompaction, significant late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR), and indications for an implantable cardioverter-defibrillator (ICD) as secondary prevention were excluded.ResultsPost-LBBP, the LVEF improved from 31.1 ± 4.0% to 61.0 ± 6.0% (P &lt; 0.001). …”
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Patellofemoral mechanics after uniplane open wedge high tibial osteotomy is superior to those after biplane open wedge high tibial osteotomy by Yi Zheng, Bin Yang, Decheng Meng, Zhijie Wang, Naihao Pan, Chen Feng, Juan Wang

“…Methods In this study, a finite element model of the knee joint was established using computed tomography (CT) and magnetic resonance imaging (MRI) data from a healthy volunteer, and a 10° varus deformity of the proximal tibia was simulated. …”
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Comparative analysis between abdominal aortic aneurysm and popliteal artery aneurysm by Marcos Vinícius Melo de Oliveira, MD, PhD, Alexandre Malta Brandão, MD, PhD, Gina Camillo Rocha Silvestre, BS, Alexandre Queiroz Silva, BS, Michele Alberto Marques, BS, Marcia Martins Reis, PhD, Maria de Lourdes Higuchi, MD, PhD, Erasmo Simão da Silva, MD, PhD

“…Methods: This study included 180 patients with AAA and 18 with PAA. Medical history and imaging data were collected. Biomechanical testing assessed arterial wall mechanical strength and elasticity, and histological and immunohistochemical analyses examined tissue composition and inflammatory markers. …”
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Comparing the efficacy of different methods in assessing cervical stromal invasion in endometrial carcinoma: a retrospective study of 2,020 patients by Ying Yang, Ying Yang, Zhijun Ye, Zhijun Ye, Yifei Zhao, Yifei Zhao, Zhengyu Li, Zhengyu Li

“…PurposeThis study aimed to assess the preoperative diagnostic efficacy of magnetic resonance imaging (MRI), computed tomography (CT), and endometrial biopsy for cervical stromal invasion (CSI) in endometrial carcinoma (EC) and to discuss the influencing factors of CSI.Material and methodsA total of 2,020 patients with EC were retrospectively analyzed in a tertiary hospital. …”
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Duodenal obstruction due to two congenital bands: a case report and literature review by Shiqiu Xiong, Kuku Ge, Chongzhi Hou, Hongbin Yang, Hanhua Zhang, Sheng Zhang, Bailing Liu, Yuewen Hao, Ying Fang, Xiaoxia Ren

“…Common symptoms included vomiting and abdominal pain, with physical examinations often showing tenderness and distension. Imaging techniques like plain x-ray, contrast x-ray, ultrasound, and computed tomography often indicated intestinal obstruction but were less effective in directly identifying congenital bands. …”
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Bladder-sparing therapy in a case report of huge muscle-invasive bladder IMT treated with 1470 nm diode laser en bloc resection followed by laparoscopic partial cystectomy by Junhao Chu, Huisheng Yuan, Zhihui Zhang, Jiajun Kan, Shishuai Duan, Zilong Wang, Zilong Wang, Zilong Wang, Muwen Wang

“…Computed tomography urography (CTU) and magnetic resonance imaging (MRI) identified a large tumor on the anterior bladder wall with muscle layer invasion, measuring approximately 5.0 × 3.9 × 4.3 cm. …”
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Improved SED-fitting Assumptions Result in Inside-out Quenching at z ~ 0.5 and Quenching at All Radii Simultaneously at z ~ 1 by Alexander de la Vega, Susan A. Kassin, Camilla Pacifici, Stéphane Charlot, Emma Curtis-Lake, Jacopo Chevallard, Timothy M. Heckman, Anton M. Koekemoer, Weichen Wang

“…We then perform radial SED fits to multiband flux profiles measured from Hubble Space Telescope images for 1440 galaxies at 0.4 <  z  < 1.5 of stellar masses 10 ^10 –10 ^11.5 M _⊙ using both the traditional and the more physically motivated assumptions. …”
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Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review by Jiangfeng Liao, Jiangfeng Liao, Wenming Hu, Wenming Hu, Shiheng Chen, Chunyu Huang, Chunyu Huang, Senwei Dong, Senwei Dong, Wanjin Chen, Wanjin Chen, Xiaochun Chen, Longfei Chen, Longfei Chen

“…Restricted hyperintensities were reported in 60.0% cases on DWI, periodic sharp wave complexes in 73.3% cases on electroencephalogram, and cerebral hypoperfusion/hypometabolism in 26.7% cases on molecular imaging. The sensitive cerebrospinal fluid biomarkers were total tau (83.3%), 14-3-3 protein (75.0%), and PrP RT-QuIC (75.0%). …”
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Decreased prefrontal activation during verbal fluency task after repetitive transcranial magnetic stimulation treatment for depression in Alzheimer’s disease: a functional near-inf... by Yuanzhi Zhao, Yuanzhi Zhao, Conglong Qiu, Conglong Qiu, Ping Lin, Ping Lin, Mei Yang, Mei Yang, Ling Huang, Ling Huang, Zheng Zhao, Zheng Zhao, Xiangping Wu, Dongsheng Zhou, Dongsheng Zhou

“…The underlying cortical changes were imaged using fNIRS. Prefrontal activation measured by fNIRS is a potential biomarker for monitoring the response of patients with depression in AD to rTMS treatment.…”
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Mutation in the COL2A1 gene is associated with acetabular dysplasia by Miaomiao Xin, Xin Guan, Xin Guan, Jiangfei Yang, Yi Li, Zhentao Man, Hongsheng Sun, Min Fu

“…Bioinformatics analysis was performed to assess the pathogenicity of the identified variant, and 3D protein modeling was conducted to predict its impact on protein structure.ResultsThe proband presented with pain in bilateral hips, and based on clinical symptoms, laboratory findings and imaging studies, the final diagnosis was considered to be acetabular dysplasia with overlapping secondary synovial chondromatosis. …”
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Artificial intelligence-based spatial analysis of tertiary lymphoid structures and clinical significance for endometrial cancer by Haruka Suzuki, Kohei Hamada, Junzo Hamanishi, Akihiko Ueda, Ryusuke Murakami, Mana Taki, Rin Mizuno, Koichi Watanabe, Hanako Sato, Yuko Hosoe, Hiroaki Ito, Koji Yamanoi, Hiroyuki Yoshitomi, Nobuyuki Kakiuchi, Ken Yamaguchi, Noriomi Matsumura, Seishi Ogawa, Hideki Ueno, Masaki Mandai

“…To comprehensively investigate the distribution of TLSs, we developed an artificial intelligence model to detect TLSs and determine their spatial locations in whole-slide images. Our model effectively quantified TLSs, and TLSs were detected in 69% of the patients with EC. …”
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