Impact of perineural tumor spread in head and neck adenoid cystic carcinoma for carbon-ion radiotherapy by Atsushi Musha, Nobuteru Kubo, Hidemasa Kawamura, Naoko Okano, Masahiro Onishi, Takeru Ohtaka, Midori Tamura, Osamu Nikkuni, Yuichi Tomidokoro, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno

“…PNTS was evaluated by magnetic resonance imaging for detecting extratumoral extension to peritumoral nerves. …”
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I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations by Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

“…The Investigation of Serial studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis (ISPY COVID-19 trial) was designed and implemented in early 2020 to evaluate investigational agents rapidly and simultaneously on a phase 2 adaptive platform. …”
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Restoration of Foveal Bulge after Resolution of Diabetic Macular Edema with Coexisting Serous Retinal Detachment by Yijun Hu, Qiaowei Wu, Baoyi Liu, Manqing Huang, Qingsheng Peng, Pingting Zhong, Xiaomin Zeng, Yu Xiao, Cong Li, Ying Fang, Tao Li, Honghua Yu, Xiaohong Yang

“…To evaluate the impact of restoration of foveal bulge (FB) in optical coherence tomography (OCT) images on visual acuity after resolution of diabetic macular edema with coexisting serous retinal detachment (SRD-DME). …”
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Cochlear Implantation: Predicting Round Window Niche Visibility Using One Measurement in High-Resolution Temporal Bone Computed Tomography by Laila Telmesani, Mona Al-Ramah, Yassin Abdelsamad, Lena Telmesani

“…The measurement was done for the angle of the basal turn of the cochlea (ABTC), which we defined as the angle formed by the cochlear basal turn and the cranium mid-sagittal plane, by 2 readers blindly from the axial images of computed tomography. The RWN visibility was classified according to the observation during surgery (through posterior tympanotomy) into full visibility, partial visibility, and invisibility. …”
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Automatic three-dimensional reconstruction of the oesophagus in achalasia patients undergoing POEM: an innovative approach for evaluating treatment outcomes by Alanna Ebigbo, Helmut Messmann, Vivian Grünherz, Miriam Elia, Alessandra Brunner, Tamara Krafft, Leo Pöller, Pia Schneider, Fabian Stieler, Bernhard Bauer, Anna Muzalyova, Sandra Nagl

“…We present an innovative approach for treatment response prediction based on an automatic three-dimensional (3-D) reconstruction of the tubular oesophagus (TE) and the lower oesophageal sphincter (LES) in patients undergoing POEM for achalasia.Methods A software was developed, integrating data from high-resolution manometry, timed barium oesophagogram and endoscopic images to automatically generate 3-D reconstructions of the TE and LES. …”
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Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum by Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu

“…Methods Using 16S rDNA amplicon sequencing, untargeted metabolomics, and multi-modal magnetic resonance imaging, we examined group differences in gut microbiome, fecal metabolome, neuroimaging measures, and cognitive variables across 30 patients with AD, 75 individuals with mild cognitive impairment (MCI), and 61 healthy controls (HC). …”
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Emirates consensus recommendations on cardiovascular risk management in type 2 diabetes by Hani Sabbour, Hani Sabbour, Hani Sabbour, Wael Almahmeed, Wael Almahmeed, Fatheya Alawadi, Fatheya Alawadi, Abdullah Shehab, Abdulamjeed Al Zubaidi, Alaaeldin Bashier, Abdul Rauf Ghulam, Fauzia Rashid, Hosam Zaky, Hussien Heshmat Kassemn, Hussien Heshmat Kassemn, Jamila Bin Adi, Juwairia Tahir, Khadija Hafidh, Mohammed Farghali, Mohamed Hassanien, Mohamed Hassanien, James Januzzi

“…Routine measurement (at least yearly) of natriuretic peptides and high-sensitivity troponins can help identify patients requiring cardiac imaging referrals. However, recommending routine measurements of natriuretic peptides and/or high-sensitivity troponins to all diabetic individuals must balance clinical judgment and cost implications. …”
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Reversible cerebral vasoconstriction syndrome in a methylphenidate-treated patient: a case report by Marie-Noëlle Osmont, Cécile Malrain, Anne-Lise Ruellan, Amine Benchikh, Emmanuelle Herlem, Elisabeth Polard, Lucie-Marie Scailteux

“…After clinical, biological and imaging examinations, clinicians concluded to a highly probable RCVS diagnosis, probably linked to methylphenidate use. …”
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Characteristics of beta parapapillary atrophy in primary angle-closure suspect by Qing Zhang, Ye Zhang, Xiaohua Pan, Hui Feng, Shuning Li, Zhi Li, Meijuan Zhang, Caixia Li, Fei Xiang, Qianqian Ji

“…Stereoscopic fundus and optical coherence tomography images were used to characterise β-PPA; the former was also used to measure the major β-PPA parameters. …”
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Maladaptive changes in the homeostasis of AEA-TRPV1/CB1R induces pain-related hyperactivity of nociceptors after spinal cord injury by JiaQi Hu, WenYong Fan, Yue Xu, XiaoFei Li, HaoYang Zhang, Shun Li, Lei Xue

“…Pharmacological and Ca2+ imaging experiments revealed that AEA induced hyperexcitability in nociceptors after SCI via the AEA-TRPV1-Ca2+ pathway, whereas activation of CB1Rs reduced SCI-induced hyperexcitability and maintained cytosolic Ca2+ concentration ([Ca2+]cyto) at low levels in the early stages of SCI. …”
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Ultra robust negative differential resistance memristor for hardware neuron circuit implementation by Yifei Pei, Biao Yang, Xumeng Zhang, Hui He, Yong Sun, Jianhui Zhao, Pei Chen, Zhanfeng Wang, Niefeng Sun, Shixiong Liang, Guodong Gu, Qi Liu, Shushen Li, Xiaobing Yan

“…Meanwhile, based on the high temperature stability of the device, a voltage-temperature fused multimodal impulse neural network was constructed to achieve 91.74% accuracy in classifying digital images with different temperature labels. This work offers a novel approach to build FN neuron circuits using NDR memristors, and provides a more competitive method to build a highly reliable neuromorphic hardware system.…”
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The Effects of Low-Impact Development Best Management Practices on Reducing Stormwater Caused by Land Use Changes in Urban Areas: A Case Study of Tehran City, Iran by Sajedeh Rostamzadeh, Bahram Malekmohammadi, Fatemeh Mashhadimohammadzadehvazifeh, Jamal Jokar Arsanjani

“…For this purpose, land use maps were extracted for a period of 23 years from 2000 to 2022 using Landsat satellite images. Then, by using a combination of geographic information system-based multi-criteria decision analysis (GIS-MCDA) method and spatial criteria, four types of LID-BMPs, including bioretention basin, green roof, grass swale, and porous pavement, were located in the study area. …”
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Assessing the Direct Impact of Typhoons on Vegetation Canopy Structure and Photosynthesis by Yaoyao Zheng, Simin Zhan, Zaichun Zhu, Sen Cao, Jiana Chen, Pengjun Zhao, Weimin Wang, Ranga B. Myneni

“…Traditional methods for assessing typhoon impacts on large-scale vegetation often compare pre- and post-typhoon satellite images. These do not account for natural variations in plant life cycles or interannual variations in environmental conditions, potentially leading to inaccurate assessments of typhoon-induced vegetation damage and recovery. …”
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The Brain Activation of Two Motor Imagery Strategies in a Mental Rotation Task by Cancan Wang, Yuxuan Yang, Kewei Sun, Yifei Wang, Xiuchao Wang, Xufeng Liu

“…Previous studies on the comparative brain mechanisms of kinesthetic imagery and visual imagery have not adopted consistent stimulus images or mature mental rotation paradigms, making it difficult to effectively compare these types of imagery. …”
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Effects of Retinol, Natural Pea Peptide and Antioxidant Blend in a Topical Formulation: In Vitro and Clinical Evidence by Brian Cook, Melanie Riggs, K. C. Holley, Helen Knaggs, Ganesh Diwakar, Edwin D. Lephart

“…Skin evaluations were conducted via bioinstrumentation (for hydration, transepidermal water loss and elasticity) and at 0, 1-, 2-, 4-, and 8-week self-assessment questionnaires and photo-imaging analysis were performed. Results RTF treatment of skin in vitro co-cultures upregulated aquaporin-3, PER1, collagen, and elastin, and downregulated expression of MMP1 and the pigmentation genes TYRP1 and MITF. …”
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Risk factors for malignancy in pediatric subacute/chronic focal craniocervical lymphadenopathy by Yishai Haimi-Cohen, Yishai Haimi-Cohen, Yishai Haimi-Cohen, Eyal Elron, Eyal Elron, Lital Oz-Alcalay, Lama Hejly, Roy Hod, Roy Hod, Liat Ashkenazi-Hoffnung, Liat Ashkenazi-Hoffnung, Liat Ashkenazi-Hoffnung

“…In univariate analysis, factors associated with malignancy included older age, increased nodal size, location (supraclavicular and lateral cervical), systemic signs such as decreased appetite and weight loss, and abnormal imaging studies. Referral by an ear, nose, throat specialist vs. a family physician or a pediatrician was also associated with malignancy. …”
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Spatiotemporal patterns of annual clear-cutting distribution in tropical and subtropical regions of China with time series Landsat and CCDC by Mingxing Zhou, Guiying Li, Dengsheng Lu, Cong Xu, Zhipeng Li, Dengqiu Li

“…This research leveraged dense time-series Landsat images (1986–2022) and a novel approach combining Continuous Change Detection and Classification (CCDC) with Random Forest to produce the first annual 30 m resolution clear-cutting map for the China’s subtropical and tropical regions. …”
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Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research by Foteini Stefania Koumpa, Diamantis Xylas, Maciej Konopka, Dieter Galea, Kirill Veselkov, Anthony Antoniou, Akash Mehta, Reza Mirnezami

“…Acquired data were then divided into hierarchical thematic categories (imaging modalities, translational biomarkers (diagnostic/prognostic/therapeutic), and delivery techniques) and subcategories. …”
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Development of Spray-Dried Micelles, Liposomes, and Solid Lipid Nanoparticles for Enhanced Stability by Shradha Dattani, Xiaoling Li, Charina Lampa, Amanda Barriscale, Behzad Damadzadeh, David Lechuga-Ballesteros, Bhaskara R. Jasti

“…<b>Results:</b> Paclitaxel-loaded micelles, liposomes, and SLN formulations were successfully converted into well-dispersed spray-dried powders with acceptable yields (71.5 to 83.5%), low moisture content (<2%), and high transition temperatures (95.1 to 100.8 °C). SEM images revealed differences in morphology, where nanocarriers spray-dried with trehalose or a combination of trehalose and L-leucine produced smooth or corrugated particle surfaces, respectively. …”
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UNCOVER: The Rest-ultraviolet to Near-infrared Multiwavelength Structures and Dust Distributions of Submillimeter-detected Galaxies in A2744 by Sedona H. Price, Katherine A. Suess, Christina C. Williams, Rachel Bezanson, Gourav Khullar, Erica J. Nelson, Bingjie Wang, John R. Weaver, Seiji Fujimoto, Vasily Kokorev, Jenny E. Greene, Gabriel Brammer, Sam E. Cutler, Pratika Dayal, Lukas J. Furtak, Ivo Labbe, Joel Leja, Tim B. Miller, Themiya Nanayakkara, Richard Pan, Katherine E. Whitaker

“…Upcoming higher-resolution 1.2 mm ALMA imaging will facilitate joint spatially resolved analysis and will directly test the dust distributions within this representative submillimeter population.…”
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