Mediators of Inflammation and Immune Responses in the Human Gastrointestinal Tract by E. Arranz, A. S. Peña, D. Bernardo

Get full text

Functional Development of the Human Gastrointestinal Tract: Hormone- and Growth Factor-Mediated Regulatory Mechanisms by Daniel Ménard

Get full text

Biological factors controlling starch digestibility in human digestive system by Cheng Li, Yiming Hu, Songnan Li, Xueer Yi, Shuaibo Shao, Wenwen Yu, Enpeng Li

Subjects: Get full text

The role of morphological adaptability in Vibrio cholerae’s motility by Jun Xu, Keigo Abe, Toshio Kodama, Marzia Sultana, Denise Chac, Susan M. Markiewicz, Hideyuki Matsunami, Erika Kuba, Shiyu Tsunoda, Munirul Alam, Ana A. Weil, Shuichi Nakamura, Tetsu Yamashiro

“…The results show that filamentous V. cholerae cells retain enhanced motility in viscous environments, indicating an evolutionary adaptation for survival in varied habitats, particularly the human gastrointestinal tract. Filamentous forms exhibited increased reversal behavior at mucin interfaces, suggesting an advantage in penetrating the mucus layer. …”
Get full text

Spontaneous Bacterial Peritonitis due to Lactobacillus paracasei in Cirrhosis by Emily Harding-Theobald, Bharat Maraj

“…Lactobacillus species colonize the human gastrointestinal tract and are rarely pathogenic. We present a case involving a cirrhotic patient who presented with sepsis and was found to have peritoneal cultures demonstrating Lactobacillus as the sole pathogen concerning for spontaneous bacterial peritonitis. …”
Get full text

Therapeutic applicability of helminths in autoimmune diseases – literature overview by Jacek Zwiernik, Tomasz Arłukowicz, Beata Zwiernik, Tomasz Matyskieła, Marta Gimeła-Dargiewicz, Agnieszka Rakowska, Beata Januszko-Giergielewicz, Ewa Rotkiewicz

“…This paper presents an overview of published studies conducted on helminths – parasites of the human gastrointestinal tract. Making use of their ability for immunomodulation may lead to the introduction of effective therapies for autoimmune diseases. …”
Get full text

The Opportunistic Pathogen Listeria monocytogenes: Pathogenicity and Interaction with the Mucosal Immune System by Markus Schuppler, Martin J. Loessner

“…Here, we discuss recent advances in our understanding of the interaction of L. monocytogenes with the host immune system that triggers the antibacterial immune responses on the mucosal surfaces of the human gastrointestinal tract.…”
Get full text

Transcriptional Regulators of Claudins in Epithelial Tight Junctions by Niamat Khan, Abdul R. Asif

“…Human gastrointestinal tract is covered by a monolayer of specialized epithelial cells that constitute a protective barrier surface to external toxic and infectious agents along with metabolic and digestive functions. …”
Get full text

Alpha-Lipoic Acid Promotes Intestinal Epithelial Injury Repair by Regulating MAPK Signaling Pathways by Yu Yang, Yong Xiao, Yue Jiang, Jiajun Luo, Jingwen Yuan, Junfeng Yan, Qiang Tong

“…Intestinal epithelial cells are an essential barrier in human gastrointestinal tract, and healing of epithelial wound is a key process in many intestinal diseases. α-Lipoic acid (ALA) was shown to have antioxidative and anti-inflammatory effects, which could be helpful in intestinal epithelial injury repair. …”
Get full text

Microbiome and Colorectal Cancer in Humans: A Review of Recent Studies by Hiroyuki Takamaru, Cynthia Tsay, Satoshi Shiba, Shinichi Yachida, Yutaka Saito

“…The gut microbiota, a collection of microorganisms in the human gastrointestinal tract, is one of the microenvironments associated with colon carcinogenesis. …”
Get full text

A Magnetically Capsule Robot for Biomedical Application by Qiang Fu, Xi Zhang, Songyuan Zhang, Chunliu Fan, Zhuocong Cai, Lili Wang

“…This paper is based on the kinetic energy theorem, combined with the principle of spiral mechanism in mechanical design foundation to construct a calculation method of energy utilization and to improve the control effect of capsule robot, suitable for the human gastrointestinal tract precise control of capsule robot to perform a variety of complex tasks. …”
Get full text

Exploring the link between gut health, diet, and food allergy by Magdalena Klimczak, Barbara Rymarczyk, Radosław Gawlik

“…The gut microbiota refers to the complex ecosystem of microorganisms, including bacteria, archaea, viruses and fungi, that inhabit the human gastrointestinal tract and play a central role in human health, contributing to a range of physiological functions. …”
Get full text

Physiological value of intestinal microflora by S. Yu. Kuchumova, Ye. A. Poluektova, A. A. Sheptulin, V. T. Ivashkin

“…Further studying of its functions, the states interfering qualitative and quantitative composition of microorganisms, colonizing human gastrointestinal tract, as well as the mechanism of action of probiotics and drugs of symptomatic action (defoamers) is necessary.…”
Get full text

What Do Gases in the Large Intestine Have to Do with Health? by Klaudia Pawełek, Patrycja Kinga Marta, Filip Maciej Huzarski, Gabriela Monika Ferfecka, Magdalena Rosa-Bończak, Agata Ossolińska, Weronika Kłosowicz, Oliver Carlton, Lucyna Stolarska, Natalia Morawiecka

“… A healthy human gastrointestinal tract contains approximately 200 ml of gas, with an average daily elimination of 600 ml. …”
Get full text

Biomimic models for in vitro glycemic index: Scope of sensor integration and artificial intelligence by Mohammed Salman C K, Muskan Beura, Archana Singh, Anil Dahuja, Vinayak B. Kamble, Rajendra P. Shukla, Sijo Joseph Thandapilly, Veda Krishnan

“…In vitro digestion models face challenges in replicating the dynamic conditions of the human gastrointestinal tract, such as enzyme variability and multi-time point analysis, leading to suboptimal predictive accuracy. …”
Get full text

PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism? by Justine Henriot, André Dallmann, François Dupuis, Jérémy Perrier, Sebastian Frechen

“…To this end, a systematic review of the absolute CYP3A expression in the human gastrointestinal tract and liver was conducted. The resulting CYP3A4 expression profile and two previously published profiles were applied to PBPK models of seven CYP3A4 substrates (alfentanil, alprazolam, felodipine, midazolam, sildenafil, triazolam, and verapamil) built‐in PK‐Sim®. …”
Get full text