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The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis
Published 2014-01-01“…Interest has, therefore, turned to host-pathogen interactions and whether aberrant immune responses to these could explain the development of arthritis. …”
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Incidence of endosymbiont bacteria Wolbachia in cowpea weevil Callosobruchus maculatus Fabricius (Coleoptera, Chrysomelidae).
Published 2024-01-01“…It is important to take these findings into account when considering host-pathogen interactions.…”
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Progress in Oral Vaccination against Tuberculosis in Its Main Wildlife Reservoir in Iberia, the Eurasian Wild Boar
Published 2012-01-01“…The study of host-pathogen interactions identified biomarkers of resistance/susceptibility to tuberculosis in wild boar such as complement component 3 (C3) and methylmalonyl coenzyme A mutase (MUT) that were used for vaccine development. …”
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The Interplay Between Viral Infection and Cell Death: A Ping-Pong Effect
Published 2025-01-01“…This study emphasizes the importance of investigating the mechanisms by which viruses control the host’s PCD machinery to gain insight into the evolutionary dynamics of host-pathogen interactions and to develop new approaches for predicting and managing viral threats. …”
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A novel metal transporter mediating manganese export (MntX) regulates the Mn to Fe intracellular ratio and Neisseria meningitidis virulence.
Published 2011-09-01“…As transition metals are essential regulators of cell growth and host pathogen interactions, we aimed to address mechanisms of Nm Mn²⁺ tolerance and its pathogenic consequences. …”
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Comprehensive Insights into Monkeypox (mpox): Recent Advances in Epidemiology, Diagnostic Approaches and Therapeutic Strategies
Published 2024-12-01“…Future recommendations include strengthening global collaboration for zoonotic disease surveillance, advancing the research on host–pathogen interactions, and developing next-generation therapeutics to address this emerging public health threat effectively.…”
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Comparative Genomics Analysis of Two Different Virulent Bovine Pasteurella multocida Isolates
Published 2016-01-01“…These results indicated that these genes or insertion sequences might be responsible for the virulence of P. multocida, providing prospective candidates for further studies on the pathogenesis and the host-pathogen interactions of P. multocida.…”
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Immune-endocrine crossroads: the impact of nuclear receptors in Tuberculosis and Chagas disease
Published 2025-02-01“…These diseases remain significant global health concerns, particularly in developing countries, highlighting the importance of understanding the molecular mechanisms underlying host-pathogen interactions mediated by NRs.…”
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Pathological and Molecular Characterization of Grass Carp Co-Infected with Two <i>Aeromonas</i> Species
Published 2025-01-01“…These findings provide novel insights into the host–pathogen interactions during <i>Aeromonas</i> co-infection in grass carp, which may facilitate the development of effective prevention and control strategies.…”
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SHASI-ML: a machine learning-based approach for immunogenicity prediction in Salmonella vaccine development
Published 2025-02-01“…IntroductionAccurate prediction of immunogenic proteins is crucial for vaccine development and understanding host-pathogen interactions in bacterial diseases, particularly for Salmonella infections which remain a significant global health challenge.MethodsWe developed SHASI-ML, a machine learning-based framework for predicting immunogenic proteins in Salmonella species. …”
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Resistance of barley cultivars approved for use in Russia to harmful organisms and toxic aluminum ions
Published 2020-10-01“…The specificity of the host– pathogen interactions necessitates a constant search for new donors of resistance for breeding, and phytosanitary monitoring of cultivars.Materials and methods. …”
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Technical considerations towards commercialization of porcine respiratory and reproductive syndrome (PRRS) virus resistant pigs
Published 2022-06-01“…As traditional methods of classical breeding and selection for trait improvement are slow, recent progress in several areas of biology including (a) understanding host–pathogen interactions, (b) inexpensive and rapid DNA sequencing, and (c) robust gene editing like CRISPR-Cas provide geneticists tools to accelerate discovery and deployment of disease resistance alleles in livestock. …”
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Identification of Pseudoperonospora cubensis RxLR Effector Genes via Genome Sequencing
Published 2024-09-01“…Subcellular localization analysis indicated that RxLR effectors exhibited fluorescence in the nucleus and plasma membrane of N. benthamiana cells, suggesting diverse roles in host-pathogen interactions. This study provides insights into the genetic diversity and functional characterization of RxLR effectors in P. cubensis. …”
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Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages.
Published 2013-01-01“…Currently, host-pathogen interactions supporting Brucella replication are poorly understood. …”
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The distribution, phenology, host range and pathogen prevalence of Ixodes ricinus in France: a systematic map and narrative review
Published 2023-09-01“…The review highlights the gaps in our knowledge of tick-host-pathogen interactions, their ecologies and their distributions, and demonstrates the need to address these gaps in order to optimize tick and tick-borne diseases prevention and control. …”
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Infection with Toxoplasma gondii triggers coagulation at the blood-brain barrier and a reduction in cerebral blood flow
Published 2025-01-01“…Conclusions Our data provide insight into the host-pathogen interactions of a CNS parasite within the brain vasculature and suggest that thrombosis and changes in cerebral hemodynamics may be an unappreciated aspect of infection with T. gondii.…”
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Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection
Published 2025-01-01“…Overall, our study provides insights into the role of lncRNAs in the host's response to HPAIV H5N1 infection in chickens and highlights potential candidates for further investigation into host–pathogen interactions. These findings could drive the development of novel control strategies for AIVs, significantly enhancing poultry health and biosecurity.…”
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Navigating Host Immunity and Concurrent Ozone Stress: Strain‐Resolved Metagenomics Reveals Maintenance of Intraspecific Diversity and Genetic Variation in Xanthomonas on Pepper
Published 2025-01-01“…Predicting and responding to how climate change affects plant‐pathosystems is challenging, as environment affects host–pathogen interactions from molecular to the community level, and with eco‐evolutionary feedbacks at play. …”
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An optimized deep-forest algorithm using a modified differential evolution optimization algorithm: A case of host-pathogen protein-protein interaction prediction
Published 2025-01-01“…Additionally, the optimized model predicted seven novel host-pathogen interactions. Finally, the model was implemented as a web application which is accessible at http://dfh3pi.covenantuniversity.edu.ng.…”
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