Intravoxel Incoherent Motion (IVIM) Diffusion-Weighted Imaging (DWI) in Patients with Liver Dysfunction of Chronic Viral Hepatitis: Segmental Heterogeneity and Relationship with Child-Turcotte-Pugh Class at 3 Tesla by Lei Ding, Lianxiang Xiao, Xiangtao Lin, Chunmei Xiong, Lingbo Lin, Shijun Chen

“…Liver IVIM could be a promising method for classifying the severity of segmental liver dysfunction of chronic viral hepatitis as evaluated by the CTP class, which provides a noninvasive alternative for evaluating segmental liver dysfunction with accurate selection of ROIs. …”
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Bone marrow mesenchymal stem cell-originated exosomes suppress activation of hepatic stellate cells through the miR-144-3p/SLC7A11 axis by Yanqin Hao, Rong Wang, Qing Zhou, Jiaolong Ren

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Antidepressant Prophylaxis Reduces Depression Risk but Does Not Improve Sustained Virological Response in Hepatitis C Patients Receiving Interferon Without Depression at Baseline: A Systematic Review and Meta-Analysis by Awad Al-Omari, Juthaporn Cowan, Lucy Turner, Curtis Cooper

“…BACKGROUND: Depression complicates interferon-based hepatitis C virus (HCV) antiviral therapy in 10% to 40% of cases, and diminishes patient well-being and ability to complete a full course of therapy. …”
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Clinical Recommendations of the Russian Scientific Liver Society and Russian Gastroenterological Association on Diagnosis and Treatment of Liver Fibrosis, Cirrhosis and Their Compl... by V. T. Ivashkin, M. V. Maevskaya, M. S. Zharkova, S. B. Zhigalova, E. A. Kitsenko, G. V. Manukyan, A. S. Trukhmanov, I. V. Maev, I. N. Tikhonov, T. A. Deeva

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Liraglutide and GLP-1(9–37) alleviated hepatic ischemia-reperfusion injury by inhibiting ferroptosis via GSK3β/Nrf2 pathway and SMAD159/Hepcidin/FTH pathway by Chenqi Lu, Cong Xu, Shanglin Li, Haiqiang Ni, Jun Yang

“…In this study, we investigated the effects of Liraglutide and GLP-1(9–37) on the ferroptosis during hepatic ischemia-repferfusion (I/R), as well as the underlying specific mechanisms. …”
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Abord laparoscopique d’un volumineux kyste hépatique simple : à propos d’un cas [A laparoscopic approach to a large simple hepatic cyst : a case report] by Meriem Bouzida, Mustapha Zeggane, Noura Zahi, Benyahia Boukhatem, Noureddine Ait Benamer

“…The radiological explorations had objectified a large hepatic cyst and an uncomplicated gall bladder lithiasis. …”
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Barriers and facilitators of integrated hepatitis B, C, and HIV screening among pregnant mothers and newborns attending maternal and newborn clinics in Koboko District, Uganda: a qualitative inquiry of providers’ perspective by John Bosco Alege, John Paul Oyore, Rose Clarke Nanyonga, Philippa Musoke, Alloys S. S. Orago

“…This study set out to assess barriers and facilitators of integrated viral hepatitis B C and HIV care model to optimize screening uptake among mothers and newborns at health facilities in Koboko District, west Nile sub-region, Uganda. …”
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Combination Treatments of Plasma Exchange and Umbilical Cord-Derived Mesenchymal Stem Cell Transplantation for Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure: A Clinical Trial in China by Wen-xiong Xu, Hong-liang He, Shun-wen Pan, Yuan-li Chen, Mei-ling Zhang, Shu Zhu, Zhi-liang Gao, Liang Peng, Jian-guo Li

“…Background. Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a common type of liver failure with a high mortality. …”
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Abord laparoscopique d’un volumineux kyste hépatique simple : à propos d’un cas [A laparoscopic approach to a large simple hepatic cyst : a case report] by Meriem Bouzida, Mustapha Zeggane, Noura Zahi, Benyahia Boukhatem, Noureddine Ait Benamer

“…The radiological explorations had objectified a large hepatic cyst and an uncomplicated gall bladder lithiasis. …”
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High Human Immunodeficiency Virus (HIV) Viral Load and Coinfection with Viral Hepatitis Are Associated with Liver Enzyme Abnormalities among HIV Seropositive Patients on Antiretroviral Therapy in the Lake Victoria Zone, Tanzania by Shabani Iddi, Caroline A. Minja, Vitus Silago, Asteria Benjamin, Jastine Mpesha, Shimba Henerico, Benson R. Kidenya, Stephen E. Mshana, Mariam M. Mirambo

“…ASAT levels were significantly high among patients with high HIV viral load (P= 0.002) while ALAT levels were significantly high among those coinfected with hepatitis C virus (P=0.017) and hepatitis B virus (P<0.001). …”
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Personalized statin therapy: Targeting metabolic processes to modulate the therapeutic and adverse effects of statins by Zhuangqi Shi, Shuxin Han

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Hepatobiliary scintigraphy and liver function changes in patients with hepatocellular carcinoma treated with 166Ho-radioembolization by Margot T.M. Reinders, Maarten J.L. Smits, Karel van Erpecum, Joep de Bruijne, Rutger C.G. Bruijnen, Dave Sprengers, Rob de Man, Erik Vegt, Jan N.M. IJzermans, Marnix G.E.H. Lam, Arthur J.A.T. Braat

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Inhibitory effects of oxyresveratrol on ERK and Smad1/2 phosphorylation and HSC activation in preventing carbon tetrachloride-induced rat liver fibrosis by Guliang Yang, Jianfeng Zhan, Yiwen Yang, Li Yuan, Peilei Wang, Chi-Tang Ho, Shiming Li

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Systematic identification of secondary bile acid production genes in global microbiome by Yuwei Yang, Wenxing Gao, Ruixin Zhu, Liwen Tao, Wanning Chen, Xinyue Zhu, Mengping Shen, Tingjun Xu, Tingting Zhao, Xiaobai Zhang, Lixin Zhu, Na Jiao

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Tenascin C-Guided Nanosystem for Precision Delivery of Obeticholic Acid in Liver Fibrosis Therapy by Yawen Wang, Lei Yang, Qing Xu, Taiyu Liu, Hongliang He, Lisha Liu, Lifang Yin

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Comparison of Resistive Index, Pulsatility Index, and Arterial Waveform at the Comparison of Resistive Index, Pulsatility Index, and Arterial Waveform at the Site of Hepatic Artery Bifurcation in Patients with and without Nonalcoholic, Non-Diabetic Fatty Liver by Hussein Soleimantabar, Saeed Nasiri, Farshad Gharebakhshi, Samaneh Ahmadi

“…Conclusion: RI, PI, and arterial waveform at the site of division of the hepatic artery can be used to diagnose these patients who need a biopsy. …”
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Canagliflozin alleviates acetaminophen-induced renal and hepatic injury in mice by modulating the p-GSK3β/Fyn-kinase/Nrf-2 and p-AMPK-α/STAT-3/SOCS-3 pathways by Abeer Bishr, Bassant M. El-Mokadem, Asmaa A. Gomaa

“…Key findings: Pre-treatment with Cana ameliorated hepatic and renal functions, whereas, on the molecular levels, Cana promoted hepatic/renal P-AMP-activated protein kinase-α/ protein kinase B (p-Akt)/Glycogen synthase kinase (p-GSK3β) protein expression. …”
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Using Laboratory Test Results for Surveillance During a New Outbreak of Acute Hepatitis in 3-Week- to 5-Year-Old Children in the United Kingdom, the Netherlands, Ireland, and Curaçao: Observational Cohort Study by Maaike C Swets, Steven R Kerr, Brian MacKenna, Louis Fisher, Merel van Wijnen, Diederik Brandwagt, Paul W Schenk, Pieter Fraaij, Leonardus G Visser, Sebastian Bacon, Amir Mehrkar, Alistair Nichol, Patrick Twomey, Philippa C Matthews, Malcolm G Semple, Geert H Groeneveld, Ben Goldacre, Iain Jones, J Kenneth Baillie

“… Abstract BackgroundIn March 2022, a concerning rise in cases of unexplained pediatric hepatitis was reported in multiple countries. Cases were defined as acute hepatitis with serum transaminases >500 U/L (aspartate transaminase [AST] or alanine transaminase [ALT]) in children aged 16 years or younger. …”
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Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways by Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba

“…Moreover, MCP minimized oxidative stress elicited by MTX in lung and liver tissues, as indicated by reduced malondialdehyde levels, elevated levels of reduced glutathione, increased superoxide dismutase activity, and upregulated Nrf2 protein expression. In hepatic and pulmonary tissues, MCP downregulated the inflammatory signaling pathway, Gal-3/TLR-4/NF-κB/TNF-α. …”
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Host 3' flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation. by Hu Zhang, Quanxin Long, Yuanjie Liu, Alexander L Marchetti, Cheng-Der Liu, Ning Sun, Haitao Guo

“…Hepatitis B virus (HBV) relaxed circular DNA (rcDNA) possesses an 8-9 nucleotide-long terminal redundancy (TR, or r) on the negative (-) strand DNA derived from the reverse transcription of viral pregenomic RNA (pgRNA). …”
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