Morphological features of autoimmune gastritis by Ye. A. Losik, L. S. Selivanova, M. Yu. Konkov, T. L. Lapina, A. S. Tertychnyi, V. T. Ivashkin

“…Clinical symptoms in the study group varied and included both severe В12-deficient anemia and normal levels of pepsinogen I, gastrin-17 and cyanocobalamine. In 4 patients Helicobacter pylori infection has been detected. According to guidelines of the Russian Society of Pathologists in all cases multiple biopsies have been taken at esophagogastroduodenoscopy. …”
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The efficacy and safety of Vonoprazan and Tegoprazan in eradication: a comprehensive systematic review and meta-analysis of randomized controlled trials by Ting Jin, Wei Wu, Lei Zhang, Han Xuan, Haixiang Zhang, Li Zhong

“…Background: Potassium-competitive acid blocker (P-CAB)-based therapies are emerging as promising alternatives for eradicating Helicobacter pylori infection. However, the comparative efficacy of P-CAB-based therapy versus proton-pump inhibitor (PPI)-based therapy in treating H. pylori infection remains uncertain. …”
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Gastritis Stages in Monozygotic and Dizygotic Dyspeptic Twins by Mindaugas Urba, Jurgita Skieceviciene, Dainius Janciauskas, Laimas Jonaitis, Limas Kupcinskas, Matteo Fassan, Massimo Rugge, Juozas Kupcinskas

“…The progression of Helicobacter pylori-associated gastritis towards atrophic gastritis is modulated by host-related and environmental factors. …”
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Alzheimer’s disease and infectious agents: a comprehensive review of pathogenic mechanisms and microRNA roles by Seyyed Sam Mehdi Hosseininasab, Rasoul Ebrahimi, Shirin Yaghoobpoor, Kiarash Kazemi, Yaser Khakpour, Ramtin Hajibeygi, Ashraf Mohamadkhani, Mobina Fathi, Kimia Vakili, Arian Tavasol, Zohreh Tutunchian, Tara Fazel, Mohammad Fathi, Mohammadreza Hajiesmaeili

“…Various viruses such as Herpes simplex virus 1 (HSV-1), Epstein–Barr virus (EBV), Cytomegalovirus (CMV), influenza viruses, and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), as well as bacteria such as Chlamydia pneumoniae (CP), Helicobacter pylori (HP), Porphyromonas gingivalis (P. gingivalis), Spirochetes and eukaryotic unicellular parasites (e.g., Toxoplasma gondii), have been linked to AD due to their ability to activate the immune system, induce inflammation and increase oxidative stress, thereby leading to cognitive decline and AD. …”
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Current research status and trends of potassium-competitive acid blockers in the treatment of acid-related diseases: a bibliometric analysis by Baoqiang Zhu, Long Chen, Xue Tao, Hong Zheng, Xia Li, Qingfang Wu, Enwu Long, Haixia Lin

“…The most popular drug in this field was vonoprazan, and research on this drug mainly focused on the effectiveness and safety evaluation of ARDs such as Helicobacter pylori infection, gastroesophageal reflux disease, peptic ulcers, etc. …”
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Psychological and autonomous nervous system features of functional gastric dyspepsia and irritable bowel syndrome, duloxetine treatment efficacy by A. P. Pogromov, G. M. Dyukova, M. L. Leonova

“…Bristol stool scale (Rome-III 2006), laboratory and instrumental methods: upper endoscopy, colonoscopy, morphological study, Helicobacter pylori breath test, routine blood biochemical tests were used. …”
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Increased Duodenal Iron Absorption through Upregulation of Ferroportin 1 due to the Decrement in Serum Hepcidin in Patients with Chronic Hepatitis C by Masanori Sato, Koji Miyanishi, Shingo Tanaka, Akira Sakurada, Hiroki Sakamoto, Yutaka Kawano, Kohichi Takada, Masayoshi Kobune, Junji Kato

“…We enrolled 24 patients with CHC and 9 patients with chronic gastritis without Helicobacter pylori infection or an iron metabolism disorder as control participants. …”
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Evidence of Helicobacter spp. in Saliva and Gastric Mucosa of Domestic Dogs in the Central Region of Rio Grande do Sul, Brazil by Daniel D. Guerra Segundo, Camila B. E. Mello, Juliana F. Cargnelutti, Mariana M. Flores, Luís F. Pedrotti, Bernardo N. Antunes, Vanessa Milech, Omar G. Velasquez, Letícia R. Martins, Saulo T. L. Pinto Filho

“…Helicobacter pylori is a spiral-shaped bacterium, which plays a role in the aetiology of gastric diseases in humans. …”
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Esophageal lesions at irritable bowel syndrome by M. G. Mnatsakanyan, O. V. Tashchyan, Yu. A. Morozova, A. P. Pogromov, G. M. Dyukova, D. V. Khalyapina

“…Methods of investigation included clinical examination, esophagogastroduodenoscopy (EGDS) colonoscopy, X-ray investigation of the upper gut, 13С-urease breath test for Helicobacter pylori, 24-hour combined intraluminal рН-impedance recording with estimation of qualitative and quantitative indicators of refluxes and index of symptom-association probability (SAP). …”
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The dynamic oral–gastric microbial axis connects oral and gastric health: current evidence and disputes by Mengying Xia, Lei Lei, Linyong Zhao, Wenqing Xu, Hongyu Zhang, Mingming Li, Jiankun Hu, Ran Cheng, Tao Hu

“…Abstract Emerging evidence indicates that oral microbes are closely related to gastric microbes and gastric lesions, including gastric atrophy, intestinal metaplasia and gastric cancer (GC). Helicobacter pylori is a key pathogen involved in GC. However, the increasing prevalence of H. pylori-negative GC and gastric dysbiosis in GC patients emphasize the potential role of other microbial factors. …”
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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes by Jersey Heitor da S. Maués, Helem Ferreira Ribeiro, Giovanny R. Pinto, Luana de Oliveira Lopes, Letícia M. Lamarão, Carla Mariana F. Pessoa, Caroline de Fátima Aquino Moreira-Nunes, Raimundo Miranda de Carvalho, Paulo P. Assumpção, Juan A. Rey, Rommel M. Rodríguez Burbano

“…When we analyzed our DEGs considering KEGG metabolic pathways, we found 12 common branches covering a wide range of biological functions, and three of them were common to all three cell lines: ubiquitin-mediated proteolysis, ribosomes, and system and epithelial cell signaling in Helicobacter pylori infection. The GC cell lines used in this study share 14 MYC-regulated genes, but their gene expression profile is different for each histological subtype of GC. …”
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Adjuvant-free, self−assembling ferritin nanoparticle vaccine coupled with influenza virus hemagglutinin protein carrying M1 and PADRE epitopes elicits cross-protective immune respo... by Yongqiang Zhao, Shuangshuang Guo, Jia Liu, Yating Wang, Bo Wang, Chun Peng, Enqi Du, Enqi Du, Enqi Du

“…This nanoparticle vaccine displayed multi-antigen targets on the surface of Helicobacter pylori ferritin, which consists of the ectodomain of hemagglutinin of the H3N2 virus and three tandem highly conserved influenza M1 epitopes fused with the universal helper T-cell epitope PADRE, named HMP-NP. …”
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Analysis of Risk Factors of Gastric Low-Grade Intraepithelial Neoplasia in Asymptomatic Subjects Undergoing Physical Examination by Yingling Liu, Yuli Cai, Si Chen, Yawen Gou, Qiaomin Wang, Mingli Zhang, Yetao Wang, Haiou Hong, Kaiguang Zhang

“…The overall incidence of LGIN was 19.73% (678/3437), while the incidence of LGIN in the asymptomatic and symptomatic groups was 19.65% (444/2259) and 19.86% (234/1178), respectively (P=0.884). The rate of Helicobacter pylori infection in this physical examination population was 39.13% (35.8% asymptomatic group, 45.5% symptomatic group; P≤0.001). …”
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Systemic risk factors for developing of primary open-angle glaucoma by E.A. Egorov, V.P. Erichev, S.Yu. Petrov, A.V. Kuroyedov, A.A. Antonov, A.A. Vitkov

“…<br> <br> <b>Key words:</b> primary open-angle glaucoma, risk factors, diabetes mellitus, arterial hypertension, hypothyroidism, obesity, Helicobacter pylori.<br> <b>For citation:</b> Egorov E.A., Erichev V.P., Onishchenko A.L. et al. …”
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Mendelian randomization and multiomics comprehensively reveal the causal relationship and potential mechanism between atrial fibrillation and gastric cancer by Zhao Sicheng, Zhao Sicheng, Zhang Jingcheng, Zhang Jingcheng, Zhang Shuo, Zhang Shuo, Lou Jiaheng, Lou Jiaheng, Cai Yan, Cai Yan, Bai Xing, Bai Xing, Jiang Tao, Jiang Tao, Jiang Tao, Zhang Guangji, Zhang Guangji, Zhang Guangji

“…High-throughput sequencing data were further used to analyze the association between the two and their impact on the survival outcome of gastric cancer.ResultsThe results showed that AF was negatively associated with gastric cancer, and further analysis revealed that this relationship was independent of GC risk factors such as chronic gastritis, Helicobacter pylori infection, and alcohol consumption. …”
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Risk factors for gastric cancer and related serological levels in Fujian, China: hospital-based case–control study by Lin Cai, Wen Wang, Ping Yuan, Lan Lin, Kuicheng Zheng, Sihan Wu, Liangxiang Huang, Bingshan Wu, Tiehui Chen, Xiaoqing Li

“…Objective To explore the relationships between gastric cancer and serum pepsinogen I (PG I), PG II, PG I/II ratio, gastrin 17 (G-17) and Helicobacter pylori infection, and to investigate dietary and lifestyle risk factors for gastric cancer in Fujian Province, China.Design A hospital-based, 1:1 matched case–control study.Setting Patients with newly diagnosed gastric cancer were recruited from the Fujian Provincial Hospital and the No. 900 Hospital of the Joint Support Force of the Chinese People’s Liberation Army between July 2014 and December 2016.Participants A total of 180 pairs of patients with gastric cancer and control subjects were recruited in the study, including 134 (74.4%) male pairs and 46 (25.6%) female pairs.Investigation and analysis measures Serological indicators were tested with ELISA kits. …”
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Prevalence of peptic ulcer disease and its associated factors in Jeddah Saudi Arabia by Muazzam Sheriff Maqbul, Reem Saleh Alzaki, Reema Sami Meeralam, Norah Abdulmajeed Alqutami, Bayan Mohammed Alturki, Lina Sultan Alhazmi, Reem Mamdouh Alaseeri, Lama Saad Alghamdi, Reem Khalid bin Brik, Shaima Tariq Mansoor Beig, Muath Saeed Alamri, Wjood Abdullah A. Alshehri, Turki Ayed Almutairi, Maha Abdullah Alqurashi, Ahmed Jamal Nasef

“…Introduction: Peptic ulcer disease's (PUD) global significance, emphasizing its health burdens and associations with factors like Helicobacter pylori infection and lifestyle habits. The need for comprehensive approaches to prevention and management. …”
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Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases by Orsolya Anna Simon, Levente Frim, Nelli Farkas, Zoltán Sipos, Nóra Vörhendi, Eszter Boros, Dániel Pálinkás, Brigitta Teutsch, Patrícia Kalló, Vivien Vass, Andrea Szentesi, Roland Hágendorn, Péter Hegyi, Bálint Erőss, Imre Szabó

“…Numerous primary (in-hospital mortality, discharge, need for endoscopic intervention, in-hospital rebleeding, length of hospitalisation, need for emergency surgery, need for endoscopic examination and need for intensive care unit) and secondary (detection of Helicobacter pylori (H. pylori), recognition of cancer as the source of bleeding, need for any kind of transfusion or clotting factor, anticoagulation therapy) outcomes were observed. …”
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Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa by W M Simmonds, Y Awuku, C Barrett, M Brand, K Davidson, D Epstein, E Fredericks, S Gabriel, S Grobler, C Gounden, L Katsidzira, V J Louw, V Naidoo, C Noel, E Ogutu, N Ramonate, N Seabi, M Setshedi, J Van Zyl, G Watermeyer, C Kassianides

“…The recommendations incorporate six areas, namely: general recommendations and practice, Helicobacter pylori, coeliac disease, suspected small bowel bleeding, inflammatory bowel disease, and preoperative care. …”
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