Correlation of Clinical, Endoscopic, and Pathological Findings among Suspected Peptic Ulcer Disease Patients in Abuja, Nigeria by Onyedika Godfrey Okoye, Oluwole Olayemi Olaomi, Alexander M.E. Nwofor, Paul Jibrin, Cephas Shallangwa Batta, Abubakar Gagarawa Yaú, Olawale A. Badejo

“…Peptic ulcer disease (PUD) remains one of the most prevalent gastrointestinal diseases and has been linked to Helicobacter pylori (H. pylori) infection. This condition may be suspected on clinical grounds, but diagnosis is established using upper gastrointestinal endoscopy. …”
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Therapeutic regimens against infection without proton pump inhibitors in patients with corpus atrophic gastritis: a real-life single-centre longitudinal observational study by Emanuele Dilaghi, Lorenzo Mosciatti, Ludovica Dottori, Irene Ligato, Gianluca Esposito, Emanuela Pilozzi, Bruno Annibale, Edith Lahner

“…Background: Efficacy of eradication regimens in Helicobacter pylori (Hp) infection is commonly reported with proton pump inhibitors (PPIs). …”
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Design, synthesis, in vitro, and in silico studies of 4-fluorocinnamaldehyde based thiosemicarbazones as urease inhibitors by Muhammad Islam, Saeed Ullah, Ajmal Khan, Zahra Batool, Suraj N. Mali, Shailesh S. Gurav, Kholood A. Dahlous, Saikh Mohammad, Javid Hussain, Ahmed Al-Harrasi, Zahid Shafiq

“…At low pH, this enzyme gives an ideal environment to Helicobacter pylori in the stomach which is the cause of gastric ulcers and peptic ulcers. …”
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Serum Prohepcidin Levels Are Lower in Patients with Atrophic Gastritis by Hyung-Keun Kim, Eun-Chul Jang, Ju-Ok Yeom, Sun-Young Kim, Hyunjung Cho, Sung Soo Kim, Hiun-Suk Chae, Young-Seok Cho

“…We investigated the relationships among serum prohepcidin, iron status, Helicobacter pylori infection status, and the presence of gastric mucosal atrophy. …”
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Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer by Yoshikazu Yoshifuku, Yoji Sanomura, Shiro Oka, Kazutaka Kuroki, Mio Kurihara, Takeshi Mizumoto, Yuji Urabe, Toru Hiyama, Shinji Tanaka, Kazuaki Chayama

“…When DL was present, HC levels in the Helicobacter pylori- (H. pylori-) eradicated group and noneradicated group were evident in 65% and 89%, a difference that was significant (p<0.001). …”
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Clinicopathological Features and Increased Expression of Toll-Like Receptor 4 of Gastric Cardia Cancer in a High-Risk Chinese Population by Guangcan Chen, Muming Xu, Jingyao Chen, Liangli Hong, Wenting Lin, Shukun Zhao, Guohong Zhang, Guo Dan, Shuhui Liu

“…Lymph node metastasis was more frequent in GCC than in EC. The Helicobacter pylori infection rate was higher but not significantly with GCC than EC. …”
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Can GastroPanel be used as a triage tool to select patients with advanced atrophic gastritis for gastroscopy? A prospective clinical validation study by Eleanor Wood, Marco Novelli, Laura Marelli, Roger Feakins, Cinzia Papadia, Ray Shidrawi, Kari Juhani Syrjänen

“…GastroPanel (Biohit Oyj; Helsinki, Finland) is an ELISA kit that measures pepsinogen I (PGI); pepsinogen II (PGII); gastrin-17 (G-17); and Helicobacter pylori IgG antibodies (Hp IgG). PGI and the PGI/PGII ratio correlate inversely with the severity of chronic atrophic gastritis (AG). …”
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Clinicopathologic Characteristics and Long-Term Outcome of Gastric Cancer Patients with Family History: Seven-Year Follow-Up Study for Korean Health Check-Up Subjects by Jooyoung Lee, Su Jin Chung, Ji Min Choi, Yoo Min Han, Joo Sung Kim

“…The proportion of patients with microsatellite instability (MSI) was also higher in groups with FHx of GC (43.2% vs. 13.2%, p=0.006). Helicobacter pylori infection rates of patients with FHx of GC tended to be higher although not significant (70.5% vs. 61.3%, p=0.188). …”
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M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity by Furui Zhang, Jiale Chen, Zhen Zhang, Jing Wu, Yuliang Qu, Linhan Ni, Guolin Zhang, Kunmei Liu, Le Guo

“…Abstract Background Helicobacter pylori (H. pylori), a specific bacterium capable of surviving in the acidic environment of the stomach, has been recognized as a group of causative agents of gastric cancer. …”
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Expressions of MMPs and TIMP-1 in Gastric Ulcers May Differentiate H. pylori-Infected from NSAID-Related Ulcers by Hsiu-Chi Cheng, Hsiao-Bai Yang, Wei-Lun Chang, Wei-Ying Chen, Yi-Chun Yeh, Bor-Shyang Sheu

“…Two major causes of gastric ulcers are Helicobacter pylori (H. pylori) infection and nonsteroidal anti-inflammatory drug (NSAID) use. …”
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A novel nomogram for predicting the morbidity of chronic atrophic gastritis based on serum CXCL5 levels by Bei Pei, Qin Sun, Yi Zhang, Ziang Wen, Wenjing Ding, Kairui Wu, Tingting Li, Xuejun Li

“…Results Multi-factorial logistic regression analysis revealed that history of smoking, family history of tumurs, Pepsinogen I (PG I), Gastrin 17 (G-17), Helicobacter pylori infection, D-dimer, and CXCL5 were independent risk factors in CAG patients. …”
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Host-symbiont-gene phylogenetic reconciliation by Menet, Hugo, Trung, Alexia Nguyen, Daubin, Vincent, Tannier, Eric

“…We finally evaluate different hypotheses on human population histories in the light of their coevolving Helicobacter pylori symbionts, reconciled together with their genes. …”
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Evaluating the Effect of Chloroform and Water Extract of Satureja khuzistanica on the Expression of Bcl-2 and Bax in Gastric Cancer Cell Line by Bagher Biglak, Asghar Tanomand, Leyla Açik, Farzad Arjomandi Rad, Gholamreza Shahsavari, Saman Kazemi, Hossein Soltanzadeh

“…Methods: The antimicrobial activities of chloroform and water extracts were screened against pathogenic bacteria [Helicobacter pylori (H. pylori)]. The cytotoxicity effect of the extracts was evaluated using an microculture tetrazolium assay on gastric cancer cell lines (AGS and KATO III) and normal gingival fibroblasts. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…At the same time, people of older age groups die from a lack of prevention of ulceration and inadequate eradication of Helicobacter pylori in patients taking non-steroidal anti-inflammatory drugs and antiplatelet agents.…”
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Portal Hypertensive Polyps as Gastroscopic Finding in Liver Cirrhosis by Firdevs Topal, Sabiye Akbulut, Cengiz Karahanlı, Süleyman Günay, Elif Sarıtaş Yüksel, Fatih Esad Topal

“…When the patient and control groups were compared as to Helicobacter pylori presence, the results showed that it was slightly higher in the dyspepsia group but the difference was not statistically significant (p>0.05). …”
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Preoperative Assessment of Patients Undergoing Bariatric Sleeve Gastrectomy: A Cross-Sectional Study by M. R. Tawfik, N. F. Aldawas, N. S. Almegbil, A. A. Bin Hamad, A. N. Alanazi, A. M. Alaidaroos, T. M. AlRawaf, A. A. Fayed

“…The purpose of this study was to explore various endoscopic findings and Helicobacter pylori (HP) infection in symptomatic and asymptomatic patients having laparoscopic sleeve gastrectomy (LSG) prior to surgery. …”
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Advance in identified targets of berberine by Penghai Sun, Ziyuan Wang, Yinchao Ma, Yuan Liu, Yintong Xue, Yan Li, Xiang Gao, Yuedan Wang, Ming Chu, Ming Chu, Ming Chu, Ming Chu

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Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers by Anca Negovan, Mihaela Iancu, Valeriu Moldovan, Septimiu Voidazan, Simona Bataga, Monica Pantea, Kinga Sarkany, Cristina Tatar, Simona Mocan, Claudia Banescu

“…In univariate analysis, factors significantly associated with ulcers were male gender (p=0.001), anticoagulants (p=0.029), nonsteroidal anti-inflammatory drugs (p=0.013), heart failure (p=0.007), liver (p=0.011) or cerebrovascular disease (p=0.004), diabetes mellitus (p=0.043), ulcer history (p=0.044), and alcohol consumption (p=0.018), but not Helicobacter pylori infection (p=0.2). According to our multivariate regression analysis results, history of peptic ulcer (OR 3.07, 95% CI 1.06–8.86), cotreatment with NSAIDs (OR 8, 95% CI 2.09–30.58) or anticoagulants (OR 4.85, 95% CI 1.33–17.68), male gender (OR 5.2, 95% CI 1.77–15.34), and stroke (OR 7.27, 95% CI 1.40–37.74) remained predictors for ulcer on endoscopy. …”
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Rifabutin and Furazolidone Could Be the Candidates of the Rescue Regimen for Antibiotic-Resistant H. pylori in Korea by Youn I Choi, Sang-Ho Jeong, Jun-Won Chung, Dong Kyun Park, Kyoung Oh Kim, Kwang An Kwon, Yoon Jae Kim, Seol So, Jeong Hoon Lee, Jin-Young Jeong, Sun-Mi Lee

“…In Korea, the rate of Helicobacter pylori (H. pylori) eradication has declined steadily as a result of increasing resistance to antibiotics, especially dual resistance to clarithromycin and metronidazole. …”
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Pharmacological activities and phytochemical evaluation of coconut crude oil and upon exposure to ozone by Mohammed S. Almuhayawi, Mohammed H. Alruhaili, Muyassar K. Tarabulsi, Soad K. Al Jaouni, Abdulmajeed A. Alqurashi, Faisal A. Alraddadi, Duaa A. Bukhari, Hibah M. Albasri, Moayad S. Waznah, Samy Selim

“…Some biological tests were done including antibacterial action versus Helicobacter pylori, anti-biofilm activity versus H. pylori, anti-hemolytic activity in the existence of H. pylori, anti-Alzheimer action, and cytotoxic effect towards A-413 cancer cell line to determine the activity of coconut oil and upon exposure to ozone. …”
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