Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis by Saben Sakalar, Engin Ozakın, Arif Alper Cevik, Nurdan Acar, Serkan Dogan, Filiz Baloglu Kaya, Taylan Kara

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Epidemiological evidence for a hereditary contribution to myasthenia gravis: a retrospective cohort study of patients from North America by Joel Oger, Joshua D Green, Bryan J Traynor, Richard J Barohn, Michael Benatar, Emanuela Bartoccion, Derrick Blackmore, Vinay Chaudhry, Manisha Chopra, Andrea Corse, Mazen M Dimachkie, Amelia Evoli, Julaine Florence, Miriam Freimer, James F Howard, Theresa Jiwa, Henry J Kaminski, John T Kissel, Wilma J Koopman, Bernadette Lipscomb, Michelanglo Maestri, Mariapaola Marino, Janice M Massey, April McVey, Michelle M Mezei, Srikanth Muppidi, Michael W Nicolle, Robert M Pascuzzi, Mamatha Pasnoor, Alan Pestronk, Carlo Provenzano, Roberta Ricciardi, David P Richman, Julie Rowin, Donald B Sanders, Zaeem Siddiqi, Aimee Soloway, Gil I Wolfe, Charlie Wulf, Daniel B Drachman

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Outcomes in stage IIA versus stage IIB/III in the PALLAS trial [ABCSG-42/AFT-05/PrE0109/BIG-14-13]) by A. DeMichele, A. C. Dueck, D. Hlauschek, M. Martin, H. Burstein, G. Pfeiler, N. Zdenkowski, A. Wolff, M. Bellet-Ezquerra, E. Winer, M. Balic, K. Miller, M. Colleoni, D. Lake, G. Rubovsky, D. Cameron, J. Balko, C. F. Singer, Z. Nowecki, H. Iwata, N. Wolmark, K. A. Parraga, H. Rugo, G. G. Steger, T. Traina, G. Werutsky, D. Czajkowska, O. Metzger, S. El-Abed, K. P. Theall, R. D. Lu, P. O’Brien, C. Fesl, E. Mayer, M. Gnant

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Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma by Li Yan, Qianchuan He, Shiv P. Verma, Xu Zhang, Ann-Sophie Giel, Carlo Maj, Kathryn Graz, Elnaz Naderi, Jianhong Chen, Mourad Wagdy Ali, Puya Gharahkhani, Xiang Shu, Kenneth Offit, Pari M. Shah, Hans Gerdes, Daniela Molena, Amitabh Srivastava, Stuart MacGregor, Claire Palles, René Thieme, Michael Vieth, Ines Gockel, Thomas L. Vaughan, Johannes Schumacher, Matthew F. Buas

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Depressive and Negative Symptoms in the Early and Established Stages of Schizophrenia: Integrating Structural Brain Alterations, Cognitive Performance, and Plasma Interleukin 6 Lev... by Fabiana Corsi-Zuelli, Gary Donohoe, Siân Lowri Griffiths, Cristina M. Del-Ben, Andrew J. Watson, Tom Burke, Paris A. Lalousis, Declan McKernan, Derek Morris, John Kelly, Colm McDonald, Saahithh R. Patlola, Carmine Pariante, Nicholas M. Barnes, Golam M. Khandaker, John Suckling, Bill Deakin, Rachel Upthegrove, Maria R. Dauvermann

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A Systematic Review of the Cost-Effectiveness of Nurse Practitioners and Clinical Nurse Specialists: What Is the Quality of the Evidence? by Faith Donald, Kelley Kilpatrick, Kim Reid, Nancy Carter, Ruth Martin-Misener, Denise Bryant-Lukosius, Patricia Harbman, Sharon Kaasalainen, Deborah A. Marshall, Renee Charbonneau-Smith, Erin E. Donald, Monique Lloyd, Abigail Wickson-Griffiths, Jennifer Yost, Pamela Baxter, Esther Sangster-Gormley, Pamela Hubley, Célyne Laflamme, Marsha Campbell–Yeo, Sheri Price, Jennifer Boyko, Alba DiCenso

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Kinetics of lymphocytosis in naïve chronic lymphocytic leukemia patients treated with covalent Bruton's tyrosine kinase inhibitors: An Italian multicenter real‐life experience by Idanna Innocenti, Antonio Mosca, Annamaria Tomasso, Andrea Galitzia, Lydia Scarfò, Francesca Morelli, Eugenio Galli, Francesca Martini, Eugenio Sangiorgi, Roberta Laureana, Giulia Benintende, Veronica Mattiello, Sabrina Chiriu, Maria I. Del Principe, Giulia Zamprogna, Massimo Gentile, Enrica A. Martino, Emilia Cappello, Maria C. Montalbano, Giuliana Farina, Vanessa Innao, Luca Stirparo, Caterina Patti, Paolo Sportoletti, Alberto Fresa, Gioacchino Catania, Marta Coscia, Silvia Bellesi, Alessandra Tedeschi, Alessandro Sanna, Andrea Visentin, Francesco Autore, Raffaella Pasquale, Livio Trentin, Marzia Varettoni, Paolo Ghia, Roberta Murru, Luca Laurenti

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Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents by Luís M. T. Frija, Bruno E. C. Guerreiro, Inês C. C. Costa, Vera M. S. Isca, Lucília Saraiva, Beatriz G. Neves, Mariana Magalhães, Célia Cabral, Maria L. S. Cristiano, Patrícia Rijo

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Photoaging smartphone app promoting poster campaign to reduce smoking prevalence in secondary schools: the Smokerface Randomized Trial: design and baseline characteristics by Michael Kreuter, Fabian N Fries, Titus J Brinker, Ute Mons, David A Groneberg, Anil Batra, Werner Seeger, Felix Herth, Julia Holzapfel, Tanja G Baudson, Katharina Sies, Lena Jakob, Hannah Maria Baumert, Marlene Heckl, Ana Cirac, Janina L Suhre, Verena Mathes, Hannah Spielmann, Nancy Rigotti, Tobias Raupach, Henning Gall, Claudia Bauer, Pat Marek, Chase H Harrison, Lava Taha, Andreas Owczarek, Felix J Hofmann, Roger Thomas

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Assessing alcohol industry penetration and government safeguards: the International Alcohol Control Study by Sarah Callinan, Gopalkrishna Gururaj, Shiwei Liu, Sally Casswell, Thomas Karlsson, Jintana Jankhotkaew, Surasak Chaiyasong, Pranil Man Singh Pradhan, Gillian Shorter, Timothy Naimi, Ingeborg Rossow, Keitseope Nthomang, June Yue Yan Leung, Mindaugas Štelemėkas, Mom Kong, Khem Karki, Steve Randerson, Lathika Athauda, Arvind Banavaram, Orfhlaith Campbell, Song Dearak, Emeka W Dumbili, Laura Romero-García, Romtawan Kalapat, Norman Danilo Maldonado Vargas, Juan Felipe Gonzalez-Mejía, Opeyemi Oladunni, Kwame Owino, Juan Camilo Herrera Palacio, Phasith Phatchana, Vanlounny Sibounheuang, Dao The Son, Kate Vallance, Wim van Dalen, Ashley Wettlaufer, Arianne Zamora

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The risk of repeated self-harm and suicide after emergency department presentation with self-harm in mental health presenters: a retrospective cohort study with data linkage in Que... by Richard A.F. Pellatt, David R. Painter, Jesse T. Young, Kairi Kõlves, Gerben Keijzers, Stuart A. Kinner, Ed Heffernan, Julia Crilly, Marc Broadbent, Amy Johnston, Melinda Martin-Khan, Paul Scuffham, Marianne Wallis, Ping Zhang

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Cohort profile: the potentially preventable burden of community-acquired pneumonia in South African adults in the era of widespread PCV13 immunisation and antiretroviral therapy ro... by Jo Southern, Kennedy Otwombe, Eileen Dunne, Khuthadzo Hlongwane, Bradford D Gessner, Michelle Wong, Cheryl Cohen, Anne von Gottberg, Elizabeth Begier, Sharon Gray, Ebrahim Variava, Tumelo Moloantoa, Neil Martinson, Firdaus Nabeemeeah, Nadia Sabet, Lebohang M Mlambo, Phetho Mangena, Pattamukkil Abraham, Floris Swanepoel, Fahima Moosa, Mark Fletcher, Bha Ndungane-Tlakula, Jerusha Naidoo, Minja Milovanovic

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Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

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Study protocol of a population-based cohort investigating Physical Activity, Sedentarism, lifestyles and Obesity in Spanish youth: the PASOS study by Susana Aznar, Camille Lassale, Santiago Felipe Gómez, Clara Homs, Julia Wärnberg, Maria Medrano, Marcela Gonzalez-Gross, Narcis Gusi, Elena Marín Cascales, Miguel González-Valeiro, Lluis Serra-Majem, Nicolás Terrados, Josep A Tur, Marta Segú, Juan Carlos Benavente-Marín, Idoia Labayen, Augusto García Zapico, Jesús Sánchez-Gómez, Fabio Jiménez-Zazo, Pedro Emilio Alcaraz, Marta Sevilla-Sanchez, Estefania Herrera-Ramos, Susana Pulgar, Maria del Mar Bibiloni, Olga Sancho, Helmut Schröder

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Desigualdades relacionadas à participação em aulas de Educação Física entre adolescentes sul-americanos: uma análise com 173.288 participantes by Raphael Henrique de Oliveira Araujo, André Oliveira Werneck, Thiago Sousa Matias, Rafael Miranda Tassitano, Clarice Maria de Lucena Martins, Nicolas Aguilar-Farias, Gilmar Mercês de Jesus, Robinson Ramírez-Vélez, Se-Sergio Baldew, Cecilia Anza-Ramirez, Mario Germán Álvarez-Álvarez, Javier Brazo-Sayavera, Danilo Rodrigues Pereira da Silva

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Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels by Thomas M. Snyder, Rachel M. Gittelman, Mark Klinger, Damon H. May, Edward J. Osborne, Ruth Taniguchi, H. Jabran Zahid, Ian M. Kaplan, Jennifer N. Dines, Matthew T. Noakes, Ravi Pandya, Xiaoyu Chen, Summer Elasady, Emily Svejnoha, Peter Ebert, Mitchell W. Pesesky, Patricia De Almeida, Hope O’Donnell, Quinn DeGottardi, Gladys Keitany, Jennifer Lu, Allen Vong, Rebecca Elyanow, Paul Fields, Hussein Al-Asadi, Julia Greissl, Lance Baldo, Simona Semprini, Claudio Cerchione, Fabio Nicolini, Massimiliano Mazza, Ottavia M. Delmonte, Kerry Dobbs, Rocio Laguna-Goya, Gonzalo Carreño-Tarragona, Santiago Barrio, Luisa Imberti, Alessandra Sottini, Eugenia Quiros-Roldan, Camillo Rossi, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angio, Paolo Bonfanti, Miranda F. Tompkins, Camille Alba, Clifton Dalgard, Vittorio Sambri, Giovanni Martinelli, Jason D. Goldman, Jason D. Goldman, James R. Heath, Helen C. Su, Luigi D. Notarangelo, Estela Paz-Artal, Joaquin Martinez-Lopez, Bryan Howie, Jonathan M. Carlson, Harlan S. Robins

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Development of a Sensitive Quantum Dot-Linked Immunoassay for the Multiplex Detection of Biochemical Markers in a Microvolumeric Format by Kalvaityte U, Bagdonas E, Kirdaite G, Kausaite-Minkstimiene A, Uzieliene I, Ramanaviciene A, Popov A, Butkiene G, Karabanovas V, Denkovskij J, Mobasheri A, Bernotiene E

“…Ursule Kalvaityte,1 Edvardas Bagdonas,1 Gailute Kirdaite,2 Asta Kausaite-Minkstimiene,3,4 Ilona Uzieliene,1 Almira Ramanaviciene,3,4 Anton Popov,3,4 Greta Butkiene,1,5 Vitalijus Karabanovas,1,5 Jaroslav Denkovskij,1 Ali Mobasheri,1,6– 8 Eiva Bernotiene1,9 1Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, LT-08406, Lithuania; 2Department of Personalised Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania; 3Department of Immunology and Bioelectrochemistry, State Research Institute Centre for Innovative Medicine, Vilnius, LT-08406, Lithuania; 4NanoTechnas - Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Vilnius, LT-03225, Lithuania; 5Biomedical Physics Laboratory, National Cancer Institute, Baublio 3b, Vilnius, LT-08406, Lithuania; 6Research Unit of Health Sciences and Technology, Faculty of Medicine, University of Oulu, Oulu, 90014, Finland; 7World Health Organization Collaborating Center for Public Health Aspects of Musculoskeletal Health and Aging, Université de Liège, Liège, B-4000, Belgium; 8Department of Joint Surgery, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, People’s Republic of China; 9Faculty of Fundamental Sciences, Vilnius Gediminas Technical University, Vilnius, LT-10223, LithuaniaCorrespondence: Eiva Bernotiene, Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Santariskiu G. 5, Vilnius, LT-08406, Lithuania, Tel +37068377130, Email eiva.bernotiene@imcentras.ltPurpose: For the diagnosis of various diseases, simultaneous sensitive detection of multiple biomarkers using low sample volumes is needed. …”
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Impact of Mobile Health (mHealth) Use by Community Health Workers on the Utilization of Maternity Care in Rural Malawi: A Time Series Analysis by Kachimanga C, Ng’ambi WF, Kazinga D, Ndarama E, Amulele MA, Munyaneza F, Abejirinde IOO, van den Akker T, Kulinkina AV

“…Chiyembekezo Kachimanga,1,2 Wingston Felix Ng’ambi,3 Doctor Kazinga,1 Enoch Ndarama,4 Mercy Ambogo Amulele,5 Fabien Munyaneza,1 Ibukun-Oluwa O Abejirinde,6,7 Thomas van den Akker,2,8 Alexandra V Kulinkina1,9,10 1Partners in Health Malawi, Neno, Malawi; 2Athena Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; 3Health Economics and Policy Unit, Department of Health Systems and Policy, Kamuzu University of Health Sciences, Lilongwe, Malawi; 4Ministry of Health, Neno, Malawi; 5Medic, Nairobi, Kenya; 6Women College Hospital Institute for Health System Solutions and Virtual Care, Toronto, ON, Canada; 7Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada; 8Department of Obstetrics and Gynaecology, Leiden University Medical Center, Leiden, Netherlands; 9Swiss Tropical and Public Health Institute, Allschwil, Switzerland; 10University of Basel, Basel, SwitzerlandCorrespondence: Chiyembekezo Kachimanga, Partners in Health Malawi, Post Office Box 56, Neno, Malawi, Email chembekachimanga@yahoo.co.ukPurpose: Maternal mortality in Malawi is high, with low coverage of maternity care being a contributing factor. …”
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Exploring the Relationship Between Sleep Apnea, Myocardial Infarct Size, and Coronary Collaterals in Acute Myocardial Infarction: A Multidisciplinary Study by Kundel V, Devarakonda K, Khan S, Suarez-Farinas M, Cohen O, Santos-Gallego C, Menegus MA, Kini A, Vengrenyuk Y, Okamoto N, Ueda H, Gidwani U, Kizer JR, Redline S, Kaplan R, Shah N

“…Vaishnavi Kundel,1 Kavya Devarakonda,1 Samira Khan,1 Mayte Suarez-Farinas,1 Oren Cohen,1 Carlos Santos-Gallego,1 Mark A Menegus,2 Annapoorna Kini,1 Yuliya Vengrenyuk,1 Naotaka Okamoto,1 Hiroshi Ueda,1 Umesh Gidwani,1 Jorge R Kizer,3 Susan Redline,4 Robert Kaplan,2,5 Neomi Shah1 1Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Albert Einstein College of Medicine, Bronx, NY, USA; 3Cardiology Section, San Francisco Veterans Affairs Health Care System and Departments of Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA; 4Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; 5Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USACorrespondence: Vaishnavi Kundel, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1232, New York, NY, 10029, USA, Tel +1-212-241-1967, Email Vaishnavi.kundel@mssm.eduPurpose: We designed a study investigating the cardioprotective role of sleep apnea (SA) in patients with acute myocardial infarction (AMI), focusing on its association with infarct size and coronary collateral circulation.Methods: We recruited adults with AMI, who underwent Level-III SA testing during hospitalization. …”
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Association of Estimated Glomerular Filtration Rate (eGFR) and High-Sensitivity C-Reactive Protein (Hs-CRP) with the Risk of New-Onset Atrial Fibrillation in Patients with Diabetes by Liu Y, Liu H, Sun D, Zheng Y, Tse G, Chen K, Qiu J, Wu S, Liu T

“…Ying Liu,1,* Hongmin Liu,1,2,* Dongkun Sun,1,* Yi Zheng,1 Gary Tse,1,3,4 Kangyin Chen,1 Jiuchun Qiu,1 Shouling Wu,2 Tong Liu1 1Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Tianjin, 300211, People’s Republic of China; 2Department of Cardiology, Kailuan General Hospital, Tangshan, 063001, People’s Republic of China; 3School of Nursing and Health Sciences, Hong Kong Metropolitan University, Hong Kong, People’s Republic of China; 4Diabetes Research Unit, Cardiovascular Analytics Group, PowerHealth Research Institute, Hong Kong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tong Liu, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, No. 23 Pingjiang Road, Hexi District, Tianjin, 300211, People’s Republic of China, Email liutong@tmu.edu.cn; liutongdoc@126.com Shouling Wu, Department of Cardiology, Kailuan General Hospital, Tangshan, 063001, People’s Republic of China, Email drwusl@163.comBackground: Both renal function decline and systemic inflammation may synergistically increase the risk of atrial fibrillation (AF). …”
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