肺癌患者肺泡巨噬细胞表现 HLA-DR 的表达 by 周凤丽, 李固本, 唐英春

“…【目的】了解肺癌患者肺泡巨噬细胞表面人白细胞抗原-DR(HLA-DR)的表达。【方法】经支气管肺泡灌洗获肺泡巨 噬细胞,贴壁分离及培养, 免疫组化方法检测 HLA-DR 表达的阳性细胞百分率。…”
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PCR-SSP 方法作HLA-DR 亚区的基因分型 by 陈汉奎　杨英浩　罗超权　伍新尧

Subjects: “…HLA-DR 抗原/ 遗传学…”
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Hypoxia impairs decitabine-induced expression of HLA-DR in acute myeloid leukaemia cell lines by Sam Humphries, Sean M. Burnard, Courtney D. Eggins, Simon Keely, Danielle R. Bond, Heather J. Lee

“…In particular, cell surface expression of the MHC class II receptor, HLA-DR, was increased by DAC treatment in normoxia, but not hypoxia. …”
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卵巢上皮癌中 HLA-DR 及 HLA-ABC 表达的临床意义

“…【目的】研究卵巢上皮癌(EOC)中HLA-DR及HLA-ABC的表达及其临床意义,为以HLA为靶点的肿瘤免疫治疗提供理论依据。【方法】应用免疫组织化学SP法检测57例卵巢上皮癌、35例卵巢良性上皮肿瘤及20例正常卵巢组织中HLA-DR及HLA-ABC的表达情况。…”
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HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells by Yoo-Wook Kwon, Hyo-Suk Ahn, Jin-Woo Lee, Han-Mo Yang, Hyun-Jai Cho, Seok Joong Kim, Shin-Hyae Lee, Heung-Mo Yang, Hyun-Duk Jang, Sung Joo Kim, Hyo-Soo Kim

“…Teratomas formed by HLA DR knockout iPSCs did not express HLA DR, and dendritic cells differentiated from HLA DR knockout iPSCs reduced CD4+ T cell activation. …”
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各型麻风病人皮肤单核细胞HLA－DR抗原表达的研究

“…应用免疫细胞化学方法观察多菌型瘤型麻风（ＬＬ）１３例，界线类偏瘤型麻风（ＢＬ）３例，界线类麻风（ＢＢ）２例，界线类偏结核样型麻风〔ＢＴ）４例，结核样型麻风（ＴＴ）２例以及５例正常人皮肤水泡液内单核细胞ＨＬＡ－ＤＲ抗原表达。结果发现，正常对照组单核细胞ＨＬＡ－ＤＲ表达率明显高于病人组（Ｐ＜０．０１）；各病人组间ＨＬＡ－ＤＲ表达率亦有显著性差别（Ｐ＜０．０１和Ｐ＜０．０５），其中以ＬＬ／ＢＬ组最低，依次为ＢＢ组、ＴＴ／ＢＴ组。…”
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Evaluating the impact of donor eGFR and HLA-DR mismatch on graft survival in living donor kidney transplants by Pooja Budhiraja, Jesse D. Schold, Jesse D. Schold, Rocio Lopez, Rocio Lopez, Susana Arrigain, Susana Arrigain, Bruce Kaplan, Bruce Kaplan

Subjects: “…HLA-DR…”
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The effect of interleukin-10 and transforming growth factor β-1 on HLA-DR expression in colonic epithelial cells by M. J. Zimmerman, G. R. Radford-Smith, D. P. Jewell

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The Early Expression of HLA-DR and CD64 Myeloid Markers Is Specifically Compartmentalized in the Blood and Lungs of Patients with Septic Shock by Tomasz Skirecki, Małgorzata Mikaszewska-Sokolewicz, Grażyna Hoser, Urszula Zielińska-Borkowska

“…Expression monitoring of monocyte HLA-DR and neutrophil CD64 could fulfill the above need. …”
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B Lymphocyte—A Prognostic Indicator in Post‐Acute Pancreatitis Diabetes Mellitus by Xiaoyan Lin, Xiaoling Li, Junsheng Wang, Huiheng Liu

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标准HLA配型与氨基酸残基配型在再次肾移植中的应用 by 黄刚, 陈立中, 王长希, 费继光, 邱江, 傅茜, 李军, 邓素雄, 陈国栋

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PCR-SSP 快速HLA-DR 基因分型法#br# 的建立及临床初步应用 by 王晓波　陈规划　郑克立

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Level of CD8 T Lymphocytes Activation in HIV-Infected Pregnant Women: In the Context of CD38 and HLA-DR Activation Markers by Stanslaus Musyoki, Simeon Mining, Paul Nyongesa

“…Blood samples were collected from the study participants and levels of activated CD8 T lymphocytes (CD38 and HLA-DR) were determined using flow cytometer and correlated with CD4 counts of the study participants. …”
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Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses by Ryutaro Oba, Motomichi Isomura, Akira Igarashi, Kinya Nagata

“…To establish T cell subset-specific biomarkers, we performed proteomic analysis with Th1- and Th2-derived EVs and identified HLA-DR as a Th1-dominated EV membrane protein. We designed a measurement system for CD3+CD4+, CD3+CD8+, and CD3+HLA-DR+ EVs to specifically determine EV subpopulations derived from CD4+, CD8+, and Th1-type T cells, respectively. …”
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幽门螺杆菌及其vacA 基因亚型和cagA 基因与胃上皮HLA-DR 抗原表达的关系 by 何　瑶, 胡品津, 何兴祥, 曾志荣, 陈　为, 彭晓忠

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The Increased Expression of HLA-DR and ICAM-1 Molecules by Human Bronchial Epithelial Cells, Induced by Activated Mononuclear Cells, is Downregulated by Nedocromil Sodium by O. Sacco, S. Lantero, L. Scarso, V. Frangova, V. Ottolini, G. A. Rossi

“…The presence of HLA-DR and ICAM-1 molecules on BECs was then evaluated by specific antibody staining and flow-cytometry analysis. …”
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The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA by Vadim Jucaud

“…The binding affinities of allo-HLA-derived peptides to recipients’ HLA-DR and HLA-DQ antigens were predicted using the NetMHCIIpan 3.1 server. …”
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Defective antigen presentation by monocytes in ESRD patients not responding to hepatitis B vaccination: impaired HBsAg internalization and expression of ICAM-1 and HLA-DR/Ia molecules by J. Stachowski, C. Barth, M. Pollok, J. Michalkiewicz, K. Madalinski, J. Maciejewski, C. A. Baldamis

“…It was found that in uraemic non-responders, (1) the internalization of HBsAg by monocytes was significantly decreasjed—HBsAg complexed with specific IgG or as immune complex isolated from patients is better internalized compared with free HBsAg; (2) during antigen presentation the expression of adhesion (ICAM-1) and accessory (HLA-DR/Ia) molecules was significantly decreased in uraemic patients, especially in non-responders; and (3) impaired internalization of HBsAg as well as a decrease in ICAM-1 and HLA-DR/Ia expression, correlated well with the blunted proliferation of CD4+ T cells stimulated by autologous monocytes induced by HBsAg.…”
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再生障碍性贫血儿童TCR Vβ亚家族T细胞克隆性增殖及其与HLA—DRB1＊15的关系 by 黄永兰, 黄绍良, 包蓉, 张绪超, 吴燕峰

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Differentiating Latent Tuberculosis from Active Tuberculosis Through Activation Phenotypes and Chemokine Markers HLA-DR, CD38, MCP-1, and RANTES: A Systematic Review and Meta-Analysis by Chaimae Kadi, Narjisse Ahmadi, Anass Houdou, Imad El Badisy, Oumnia Bouaddi, Zakaria Mennane, Nouhaila Najimi, Maryam Benlamari, Saber Boutayeb, Mohamed Khalis, Noureddine EL Mtili, Fouad Seghrouchni

“…Objectives: To assess the diagnostic accuracy of specific biomarkers (HLA-DR + IFNγ + , CD38 + IFNγ + , MCP-1, and RANTES) in differentiating aTB from LTBI. …”
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