GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand by Tomoaki Suzuki, Ken Kadoya, Takeshi Endo, Miwako Yamasaki, Masahiko Watanabe, Norimasa Iwasaki

“…Finally, local administration of GFRα1 into injured sciatic nerve promoted functional recovery. These findings reveal a novel role of GFRα1 as a ligand, the molecular mechanism supporting axon regeneration by RSCs, and a novel therapy for peripheral nerve repair.…”
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Anodal tDCS and virtual reality gait rehabilitation in individuals with chronic stroke: a case series report by Aracely Marks, Shelley Oliveira Barbosa, Daniella Napoli, Susan E. D'Andrea

“…Emerging technologies such as virtual reality (VR) and transcranial direct current stimulation (tDCS) have shown potential to enhance neuroplasticity and functional recovery, suggesting that their combined use could offer a novel pathway for stroke rehabilitation.ObjectiveThis study evaluated the efficacy of an integrated VR and tDCS treadmill training protocol in improving gait and mobility outcomes among individuals with chronic stroke.MethodsFive chronic stroke patients were recruited for this study. …”
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An Efficient Protocol for Deriving Liver Stem Cells from Neonatal Mice: Validating Its Differentiation Potential by Sugapriya Dhanasekaran, Devilakshmi Sithambaram, Kavitha Govarthanan, Bijesh Kumar Biswal, Rama S. Verma

“…Thus, the unlimited availability of cell type favors setting up the functional recovery of the damaged liver, ensuring ahead success towards treating liver diseases. …”
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Neuroprotective Effects of Collagen-Glycosaminoglycan Matrix Implantation following Surgical Brain Injury by Jia-Hui Chen, Wei-Cherng Hsu, Kuo-Feng Huang, Chih-Huang Hung

“…Earlier reports revealed that collagen-glycosaminoglycan (CG) matrix implantation promotes angiogenesis, neurogenesis, and functional recovery following surgical brain injury (SBI). …”
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Depression after Stroke and Risk of Mortality: A Systematic Review and Meta-Analysis by Francesco Bartoli, Nicoletta Lillia, Annamaria Lax, Cristina Crocamo, Vittorio Mantero, Giuseppe Carrà, Elio Agostoni, Massimo Clerici

“…Depression after stroke may have great burden on the likelihood of functional recovery and long-term outcomes. Objective. To estimate the association between depression after stroke and subsequent mortality. …”
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Hypoxia-induced conversion of sensory Schwann cells into repair cells is regulated by HDAC8 by Nadège Hertzog, Mert Duman, Maëlle Bochud, Valérie Brügger-Verdon, Maren Gerhards, Felicia Schön, Franka Dorndecker, Dies Meijer, Robert Fledrich, Ruth Stassart, Devanarayanan Siva Sankar, Jörn Dengjel, Sofía Raigón López, Claire Jacob

“…Our study indicates that this phenotype switch is regulated by different mechanisms in sensory and motor SCs and is accelerated by HDAC8 downregulation, which promotes sensory axon regeneration and sensory function recovery.…”
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The impact of depression and anxiety disorders on postoperative outcomes for patients having total hip or knee arthroplasty: Protocol of a meta-analytic study from cohort studies. by Liang Lin, Qing Zhang, Min Xu, Zhihong Xiao, Guosong Xu, Zubing Mei

“…Inclusion criteria will focus on preoperative psychiatric diagnoses, clearly defined postoperative outcomes (such as complications, functional recovery measures, pain, length of stay, and patient-reported outcomes). …”
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Captopril Pretreatment Produces an Additive Cardioprotection to Isoflurane Preconditioning in Attenuating Myocardial Ischemia Reperfusion Injury in Rabbits and in Humans by Yi Tian, Haobo Li, Peiyu Liu, Jun-mei Xu, Michael G. Irwin, Zhengyuan Xia, Guogang Tian

“…Iso+Cap additively reduced cellular injury that was associated with improved postischemic myocardial functional recovery and reduced myocardial apoptosis and attenuated oxidative stress. …”
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Treatment of unstable pelvic fractures with double INFIX by Xu-Song Li, Jun-Le Wu, Liben Huang, Lin Ye, Jie-Feng Huang

“…Key observational indicators were fracture reduction quality (assessed using Matta’s criteria), fracture healing, functional recovery (evaluated with the Majeed function assessment criteria), and incidence of complications. …”
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Usefulness of body composition assessment by bioelectrical impedance vector analysis in subacute post-stroke patients in rehabilitation by Alessandro Guerrini, Mariacristina Siotto, Carola Cocco, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Stefania Lattanzi, Sabina Insalaco, Yeganeh Manon Khazrai, Irene Giovanna Aprile

“…The change in modified Barthel Index (mBIT1-mBIT0) was assessed to evaluate the improvement in functional recovery. BIVA revealed that both adult patients (< 65 years, n = 29) and elderly patients (≥ 65 years, n = 58) exhibited high body fluid overload and low muscle mass. …”
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Transcranial Direct Current Stimulation in Stroke Rehabilitation: A Review of Recent Advancements by Andrea Gomez Palacio Schjetnan, Jamshid Faraji, Gerlinde A. Metz, Masami Tatsuno, Artur Luczak

“…The pathological processes following stroke may provide an exemplary system to investigate how tDCS promotes neuronal plasticity and functional recovery. Changes in synaptic function after stroke, such as reduced excitability, formation of aberrant connections, and deregulated plastic modifications, have been postulated to impede recovery from stroke. …”
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Case report: Movement-related neuroplasticity in a patient after spinal cord injury in response to task-oriented bimanual training by Di Ma, Roy Rongyue Zeng, Sofina Sy Chan, Yu Pan, Jack Jiaqi Zhang

“…Therefore, we conducted a case study to investigate the effects of robot-assisted task-oriented bimanual training (RBMT) on upper limb function, activities of daily living, and movement-related sensorimotor activity in a patient with SCI.MethodsA patient with bilateral upper limb paresis due to incomplete cervical SCI underwent 20 sessions of RBMT. Functional recovery was measured using clinical scales for upper limb motor function and activities of daily living. …”
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The Clinical Outcomes of Arthroscopic Tenotomy versus Tenodesis with Medium-to-Massive Rotator Cuff Tear in the Elderly: A Retrospective Study by Song K, Lu G, Cai M, Sun Q

“…No difference was observed in the rates of complications and revision between the groups.Conclusion: For people over 60 years of age with medium to massive rotator cuff tears, postoperative shoulder function of tenodesis is superior to tenotomy, and functional recovery is relatively more stable after tenodesis than after tenotomy.Keywords: tenodesis, tenotomy, aged population, arthroscopy, rotator cuff tear…”
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Outcome of Management of Midshaft Clavicular Fractures with Titanium Elastic Nail System: A Case Series by Karthik Chithartha, Vanasekar Mokkasamy

“…Conclusion: Surgical stabilization with TENS showed better results for patients with type A and B midclavicular fractures with respect to early functional recovery, minimally invasive, less operative time, and early mobilization. …”
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Human neural stem cell–derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway by Jiayi Wang, Mengke Zhao, Dong Fu, Meina Wang, Chao Han, Zhongyue Lv, Liang Wang, Jing Liu

“…We found that administration of human neural stem cell–derived extracellular vesicles to an ischemic stroke rat model reduced the volume of cerebral infarction and promoted functional recovery by alleviating neuronal apoptosis. The human neural stem cell–derived extracellular vesicles reduced neuronal apoptosis by enhancing phosphorylation of phosphoinositide 3-kinase, mammalian target of rapamycin, and protein kinase B, and these effects were reversed by treatment with a phosphoinositide 3-kinase inhibitor. …”
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Ketogenic metabolic therapy for schizoaffective disorder: a retrospective case series of psychotic symptom remission and mood recovery by Nicole Laurent, Erin L. Bellamy, Katherine A. Tague, Donika Hristova, Ally Houston

“…Patients either achieved full psychiatric deprescription or were in the process of deprescription at time of follow-up.ConclusionThis case series demonstrates that ketogenic metabolic therapy can resolve chronic psychotic and mood symptoms in patients with schizoaffective disorder, leading to full remission and significant functional recovery and reported improvements in quality of life that extend beyond symptom control with standard of care interventions.…”
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Biomaterial-based strategies: a new era in spinal cord injury treatment by Shihong Zhu, Sijun Diao, Xiaoyin Liu, Zhujun Zhang, Fujun Liu, Wei Chen, Xiyue Lu, Huiyang Luo, Xu Cheng, Qiang Liao, Zhongyu Li, Jing Chen

“…With advancements in tissue engineering and regenerative medicine, emerging strategies for spinal cord injury repair now involve nanoparticle-based nanodelivery systems, scaffolds, and functional recovery techniques that incorporate biomaterials, bioengineering, stem cell, and growth factors as well as three-dimensional bioprinting. …”
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Application of Transcranial Magnetic Stimulation to Improve Upper Limb Motor Function Following Cerebral Infarction: A Clinical Case Analysis by Greta Gimbutaitė, Paulina Stočkūnaitė, Laura Petrusevičienė

“…In this clinical case, marked improvements in the patient’s motor functions and independence were observed, supporting the efficacy of TMS as an adjunct  to standard rehabilitation techniques for enhancing functional recovery following a cerebral infarction. …”
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Predictive Modeling of Long-Term Care Needs in Traumatic Brain Injury Patients Using Machine Learning by Tee-Tau Eric Nyam, Kuan-Chi Tu, Nai-Ching Chen, Che-Chuan Wang, Chung-Feng Liu, Ching-Lung Kuo, Jen-Chieh Liao

“…Background: Traumatic brain injury (TBI) research often focuses on mortality rates or functional recovery, yet the critical need for long-term care among patients dependent on institutional or Respiratory Care Ward (RCW) support remains underexplored. …”
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Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype by Eunhee Park, Jungsoo Lee, Won Hyuk Chang, Ahee Lee, Friedhelm C. Hummel, Yun-Hee Kim

“…Thus, the BDNF genotype may need to be considered as a factor influencing neuroplasticity and functional recovery in patients with stroke. This trial is registered with http://www.clinicaltrials.gov: NCT03647787.…”
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