Histone Deacetylase Inhibitor Scriptaid Alleviated Neurological Dysfunction after Experimental Intracerebral Hemorrhage in Mice by Heng Yang, Wei Ni, Hanqiang Jiang, Yu Lei, Jiabin Su, Yuxiang Gu, Liangfu Zhou

“…In addition, Scriptaid improved neurological function recovery and alleviated white matter injury 35 d after ICH. …”
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GABAB receptors regulate the neural stem cell potential of Pkd2l1+ cerebrospinal fluid-contacting neurons via the PI3K/Akt signaling pathway by Liang Cao, Wei-Hong Yan, Wenjun Pi, Yi Zhang, Yan-Xiang Xiong, V. Wee Yong, Mengzhou Xue, Qing Li, Chunfu Zheng, Leiluo Yang

“…Additionally, this activation mitigated vacuole loss and neuronal damage in the pericentral canal region of the spinal cord, attenuated myelin and axonal loss within the spinal cord, and facilitated motor function recovery in SCI model mice. Mechanistically, GABABR primed quiescent Pkd2l1+ CSF-cNs for cell cycle reentry through the activation of PI3K/Akt signaling. …”
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Incidence Of Acute Kidney Injury In Mild, Moderate And Severe Cases Of Coronavirus Disease by Mahvesh Mahmud, Ashok Kumar, Khurram Baqai

“…The research also assessed information about therapy (antivirals, immunomodulators, RRT) and results (renal function recovery or death). Results:  After excluding patients with obstructive AKI, a total of 180 (mean age 50.1 years) of 104 males and 76 females were included in the research. 120 patients were found to have prerenal, and 60 had intrinsic AKI with significant differences between mild, moderate, and severe cases (p=0.004). …”
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Anti-Factor H Antibodies in Egyptian Children with Hemolytic Uremic Syndrome by Shereen Shawky, Hesham Safouh, Mona Gamal, Mohammed M. Abbas, Azza Aboul-Enein, Toshihiro Sawai, Yosra Fahmy, Heba Selim

“…All patients who started immunosuppressives early together with plasmapheresis upon detection of their anti-FH had complete renal function recovery. Conclusion. The high frequency of AI-HUS revealed in Egyptian HUS children in our study highlights the importance of implementing anti-FH testing in Egypt to provide early recognition for immediate proper management, including early immunosuppressive therapy, and hence improving patient outcomes.…”
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Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury by Zhida Ma, Congpeng Meng, Xiang Wang, Yuanzhe Zhao, Jingwen Wang, Yihao Chen, Yiteng Li, Yan Jiang, Fangru Ouyang, Jianjian Li, Meige Zheng, Li Cheng, Juehua Jing

“…In vivo, trehalose administration markedly reduced myelin debris accumulation, inhibited foamy macrophage formation, suppressed inflammatory responses, decreased fibrotic scarring, and promoted axonal growth and motor function recovery after SCI. These beneficial effects of trehalose may be related to the overexpression of transcription factor EB (TFEB), a key regulator of the autophagy-lysosomal system, which can rescue autophagic dysfunction in foamy macrophages and inhibit inflammatory responses. …”
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EEG Correlates of Central Origin of Cancer-Related Fatigue by Didier Allexandre, Dilara Seyidova-Khoshknabi, Mellar P. Davis, Vinoth K. Ranganathan, Vlodek Siemionow, Declan Walsh, Guang H. Yue

“…This information should guide the development and use of rehabilitative interventions that target the central nervous system to maximize function recovery.…”
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Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury by Junjin Li, Hongda Wang, Yuanquan Li, Chunzhen Wang, Haiwen Feng, Yilin Pang, Jie Ren, Chuanhao Li, Erke Gao, Dejing Zhang, Dunxu Hu, Pengtian Zhao, Han Ding, Baoyou Fan, Tao Zhang, Xiaomeng Song, Zhijian Wei, Guangzhi Ning, Yong-Qiang Li, Shiqing Feng

“…Additionally, EJCDs attenuate the immune response in the spleen, leukocytes’ reservoir, following spinal cord injury by diminishing the local infiltration of monocytes and macrophages while promoting motor function recovery. These effects are mediated through the downregulation of CCAAT enhancer binding protein-β expression in the spleen and the upregulation of FZD4 protein expression in Lin− Sca-1+ c-kit+ cells (LSKs) within the bone marrow. …”
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Nerve root magnetic stimulation regulates the synaptic plasticity of injured spinal cord by ascending sensory pathway by Ya Zheng, Lingyun Cao, Dan Zhao, Qi Yang, Chunya Gu, Yeran Mao, Guangyue Zhu, Yulian Zhu, Jing Zhao, Dongsheng Xu

“…However, our understanding of the neurophysiological mechanisms by which nerve root magnetic stimulation facilitates motor function recovery in the spinal cord is limited, and its role in neuroplasticity remains unclear. …”
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Research Progress on Responsiveness of Activities of Daily Living Scales of Patients with Stroke by XUE Kaiwen, LIU Xiangxiang, ZHANG Zeyu, WANG Yulong

“…For patients in chronic stage of stroke, their physical function recovery has almost reached a plateau, and their ADL ability recovery mainly focuses on family and social life, but BI, FIM and mRS scale lack evaluation items about family and social life, resulting in poor responsiveness. …”
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Effect of Functional Electrical Stimulation on Improving Upper Extremity Motor Function in Stroke Patients Revealed by fMRI:a Controlled Study by Fangfang ZHENG, Huihua LIU, Tiebin YAN, Xiaokun JIN, Xiaohui DUAN, Jun SHEN

“…Laterality indexes (LIs) were also calculated and the relationship of LIs and upper extremity function recovery was investigated.Results:Besides contralateral premotor cortex (PMC), inferior parietal lobule (IPL), cingulate motor area (CMA) and cerebellum (CRB), contralateral SMC was mainly activated by FES in control group. …”
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Deanxit Combined with Cognitive Behavioral Therapy in Treating 31 Cases of Post-stroke Depression by Dujuan GE, Liyu WU, Sanfeng SUN, Lei SHANG, Qingjuan YANG, Xiaoru YANG, Qingxi ZHAO

“…The curative effect was assessed by Hamilton depression scale (HAMD), the neurologic function recovery was measured by national institutes of health stroke scale (NIHSS) and modified Barthel index (MBI), and the drug safety was evaluated by treatment emergent symptom scale (TESS).Results:After two courses, the total effective rate of the experimental group (93.5%) was higher than that of the control group (79.3%), and the difference was significant (<italic>P</italic>&lt;0.05); after a course of treatment, the HAMD score in the two groups was decreased significantly compared with that before the treatment (<italic>P</italic>&lt;0.01); the weekly score in the treatment group was lower than that of the control group, and the difference was significant at the first weekend and the second weekend (<italic>P</italic>&lt;0.05, <italic>P</italic>&lt;0.01). …”
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Research Progress of Flexible Wearable Devices in Rehabilitation Medicine by Zijun HE, Qing ZENG, Ze GONG, Rong CHEN, Hang QU, Shilin LI, Pengcheng LU, Jihua ZOU, Guozhi HUANG

“…All these applications make wearable devices a good tool to achieve the ultimate goal of rehabilitation medicine, which is function recovery and health promotion, thus wearable devices are meant to play an important role in rehabilitation medicine. …”
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Experimental Study of Enriched Environment on Neurological Functional Repair in Rats with Cerebral Ischemia-reperfusion Injury by Kewei YU, Yi WU, Hongyu XIE, Gang LIU, Junfa WU

“…There were significant statistical differences between the enriched environment group and the standard environment group for the pressure of the foot, the area of foot contact with the contact surface of rats (<italic>P</italic>&lt;0.05).Conclusion:Enriched environment can promote the autonomic movement of rats, and the enriched environment can promote the neurological function recovery of rats after cerebral ischemia/reperfusion injury. …”
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Exosomes from Human Gingiva-Derived Mesenchymal Stem Cells Combined with Biodegradable Chitin Conduits Promote Rat Sciatic Nerve Regeneration by Feng Rao, Dianying Zhang, Tengjiaozi Fang, Changfeng Lu, Bo Wang, Xiao Ding, Shuai Wei, Yiran Zhang, Wei Pi, Hailin Xu, Yanhua Wang, Baoguo Jiang, Peixun Zhang

“…Histology, electrophysiology, and gait analysis were used to test the effects of exosomes on sciatic nerve function recovery in vivo. We have successfully cultured GMSCs and isolated exosomes. …”
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Progression of Left Ventricular Dysfunction and Remodelling under Optimal Medical Therapy in CHF Patients: Role of Individual Genetic Background by Marzia Rigolli, Mariantonietta Cicoira, Corinna Bergamini, Andrea Chiampan, Andrea Rossi, Corrado Vassanelli

“…ACE I/D and β1AR Arg389Gly polymorphisms are independent predictors of reverse remodeling and systolic function recovery in CHF patients under optimal treatment.…”
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Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair by Penghui Wang, Zaifeng Chen, Ping Li, Abdullah Al Mamun, Shaoxia Ning, Jinjing Zhang, Chonghui Tang, Tianmiao Sun, Jian Xiao, Xiaojie Wei, Fenzan Wu

“…This intervention additionally preserves the integrity of the blood-spinal cord barrier, optimizes the spinal cord microenvironment, reduces glial scarring, promotes axonal regeneration, and enhances motor function recovery in SCI mice. In summary, our investigations highlight the potential of this disease-specific drug delivery system as a promising therapeutic approach for the treatment and management of SCI.…”
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The impact of dietary fiber on colorectal cancer patients based on machine learning by Xinwei Ji, Lixin Wang, Pengbo Luan, Jingru Liang, Weicai Cheng

“…The study compared infection stress index, inflammatory factors, nutritional status, intestinal function recovery, and complication incidence between groups. …”
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Effects of fluconazole and amphotericin B in the control of cryptococcal pneumonia in vivo by Zhao Yu, Zhihao Liu, Jiaojiao Qian, Yuanyuan Qian

“…These findings indicate that Fluconazole combined with Amphotericin B not only enhances clinical efficacy by mitigating inflammation but also supports lung function recovery with a favourable safety profile, highlighting its utility in managing cryptococcal pneumonia effectively.…”
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Tacrolimus and mycophenolate mofetil in corticosteroid-resistant hepatitis secondary to tislelizumab: a case report by Chang Jiang, Shanxian Guo

“…Although the patient still responded to TAC combined with MMF, liver function recovery took a longer time. Due to persistent liver dysfunction, the patient failed to receive second-line chemotherapy and ultimately passed away due to disease progression. …”
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Performance Comparison of Different Neuroimaging Methods for Predicting Upper Limb Motor Outcomes in Patients after Stroke by Jingyan Tao, Zhaoqing Li, Yang Liu, Jianhua Li, Ruiliang Bai

“…CST‐wLL<1.799 cc was correlated with a considerable rate (>70%) of upper limb motor function recovery. CST-wLL showed a comparable area under the curve (AUC) to that of the CST-FAAI (p=0.71). …”
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