Hydrogen Sulfide Promotes Functional Endometrium Recovery via Regulating Pyroptosis in Severe Endometrial Injury: A Prospective Laboratory Based Randomized Control Trial by Haiyan Shan, Mingyuan Xu, Jie Ni, Ling Zhou, Mengchun Xue, Jun Xue, Xiaohuan Yuan, Luyang Tao, Mingyang Zhang, Hong Zhang

“…The aim of this study is to elucidate the role of H2S in facilitating functional recovery of the endometrium following injury in a murine model. …”
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Diabetic Ephrin-B2-Stimulated Peripheral Blood Mononuclear Cells Enhance Poststroke Recovery in Mice by Rose Hilal, Marine Poittevin, Adrien Pasteur-Rousseau, Adrien Cogo, Gabrielle Mangin, Marie Chevauché, Yasmine Ziat, José Vilar, Jean-Marie Launay, Jean-François Gautier, Dong Broquères-You, Bernard I. Levy, Tatyana Merkulova-Rainon, Nathalie Kubis

“…At D14, microvessel density was decreased and functional recovery was enhanced compared to PBS-treated mice, whereas plasma levels of BDNF, a major regulator of neuroplasticity, were increased in mice treated with PB-MNC+ compared to the other two groups. …”
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Early Mobilization in Post-Orthopedic Surgery Patients: A Scoping Review by Rhamelani P, Mahdhiya NZ, Yoviana I, Jessica J, Komariah M

“…For further research, it is hoped that it can increase the research sample of post-orthopedic surgery patients in determining the effectiveness of various other early mobilization interventions in post-orthopedic surgery patients so that the review article can cover a wider range.Plain Language Summary: This literature review was done to describe various types of effective early mobilization that can be carried out in patients after orthopedic surgery to speed up the functional recovery process. Researchers obtained 8 research articles that conducted research related to early mobilization in patients after orthopedic surgery. …”
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Longitudinal Changes of Sensorimotor Resting-State Functional Connectivity Differentiate between Patients with Thalamic Infarction and Pontine Infarction by Peipei Wang, Zhenxiang Zang, Miao Zhang, Yanxiang Cao, Zhilian Zhao, Yi Shan, Qingfeng Ma, Jie Lu

“…The different patterns of sensorimotor functional damage and reorganization in patients with pontine infarction and thalamic infarction may provide insights into the neural mechanisms underlying functional recovery after stroke.…”
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RETRACTED ARTICLE: Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11 by Duanfeng Jiang, Xin Wu, Xiaoying Sun, Wei Tan, Xin Dai, Youbang Xie, Ashuai Du, Qiangqiang Zhao

“…The functional genes of the PI3K/AKT/mTOR signaling pathway were identified, and the functional significance of miR-7-5p in AML cells was determined using a functional recovery assay. AML cells were co-cultured with exosomes originating from BMSCs overexpressing miR-7-5p to determine cell–cell regulation by Exo-miR-7-5p, as well as in vitro and in vivo functional validation via gain- and loss-of-function methods. …”
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High spatial resolution gene expression profiling and characterization of neuroblasts migrating in the peri-injured cortex using photo-isolation chemistry by Takuya Miyamoto, Kazuya Kuboyama, Mizuki Honda, Mizuki Honda, Yasuyuki Ohkawa, Shinya Oki, Shinya Oki, Kazunobu Sawamoto, Kazunobu Sawamoto

“…When the brain is injured, some neuroblasts initiate migration toward the lesion and attempt to repair the damaged neuronal circuitry, but their low regeneration efficiency prevents functional recovery. Elucidation of the molecular basis of neuroblast migration toward lesions is expected to lead to the development of new therapeutic strategies for brain regenerative medicine. …”
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Research Progress of Intelligent Evaluation and Virtual Reality Based Training in Upper Limb Rehabilitation afrer Stroke by XIE Qiurong, LIN Wanqi, ZHANG Qi, SHENG Bo, ZHANG Yanxin, HUANG Jia

“…Combining the FTHUE rehabilitation program with VR training can more effectively promote patients' motor function recovery. Future research can select the corresponding FTHUE rehabilitation program based on the objective assessment results of the FTHUE scale, which can enable the development of individualized training programs and effectively integrate the principles of rehabilitation training. …”
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Radial head arthroplasty vs. open reduction and internal fixation in Mason 3 radial head fractures: meta-analysis of prospective trials by Domenico De Mauro, MD, Sami Abou Chakra, Francesco Liuzza, MD, Amarildo Smakaj, MD, Giuseppe Rovere, MD, PhD, Giulio Maccauro, MD, Omar El Ezzo, MD

“…Moreover, the standardized mean difference analysis suggests that the ORIF group demonstrates a lower mean Broberg and Morrey Elbow score in comparison to the RHA group, with a higher functional recovery in RHA group.…”
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Comparative study of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting for the treatment of os... by Xinyu Tang, Xinkun Han, Haitao Fu, Youliang Shen, Dongfang Zhang, Qinwei Guo, Chao Qi

“…Conclusion Arthroscopic autologous cancellous bone grafting showed superior early functional recovery at the 3-month follow-up compared to medial malleolar osteotomy combined with autologous periosteal iliac bone grafting, with shorter surgical time and avoiding osteotomy. …”
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Diagnosis and Treatment of Golfer's Elbow: A Review of Therapeutic Approaches by Karol Dzwonnik, Urszula Zelik, Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Wiktoria Domino, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“…A multimodal, personalized approach ensures optimal tendon healing, functional recovery, and long-term symptom relief. …”
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Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regenera... by Zhaoyang Gong, Zhenhao Chen, Dachuan Li, Xiao Lu, Jianwei Wu, Hanqiu Sun, Ximeng Wang, Siyang Liu, Xinlei Xia, Feizhou Lu, Jianyuan Jiang, Chi Sun, Hongli Wang, Feng Zeng, Xiaosheng Ma

“…In a rat SCI model, it facilitated functional recovery and attenuated inflammation. Conclusion The Lightgel/NGF/CeMn NP-PEG composite shows significant therapeutic promise for SCI, effectively eliminating ROS, promoting M2 macrophage polarization, reducing pro-inflammatory cytokines, and supporting neuronal regeneration. …”
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Utilization of Blood Flow Restriction Therapy with a Former Triathlete After Total Knee Arthroplasty: A Case Report by Christopher Keating, Stephanie Muth, Cameron Hui, Lisa T Hoglund

“…The KOOS-Sport & Recreation subscale may be more responsive to monitor functional recovery compared to the KOOS-JR, possibly due to the subject's athletic background…”
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The association between neighborhood social vulnerability and community-based rehabilitation after stroke by Shuqi Zhang, Elizabeth R. Mormer, Anna M. Johnson, Cheryl D. Bushnell, Pamela W. Duncan, Fang Wen, Shweta Pathak, Amy M. Pastva, Janet K. Freburger, Sara B. Jones Berkeley

“…Abstract Background Timely rehabilitative care is vital for functional recovery after stroke. Social determinants may influence access to and use of post-stroke care but have been inadequately explored. …”
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Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer by Leopold Harnoncourt, Martin Schmoll, Christopher Festin, Laurenz Pflaum, Markus Breuss, Johanna Klepetko, Dominik C. Dotzauer, Florian J. Jaklin, Udo Maierhofer, Philipp Tratnig-Frankl, Oskar C. Aszmann, Oskar C. Aszmann

“…This approach enhances functional recovery and has been demonstrated to be effective in both preclinical models and clinical settings. …”
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Modulation of brain activity in brain-injured patients with a disorder of consciousness in intensive care with repeated 10-Hz transcranial alternating current stimulation (tACS): a... by David Williamson, Francis Bernard, Stefanie Blain-Moraes, Caroline Arbour, Virginie Williams, Louis de Beaumont, Catherine Duclos, Béatrice P De Koninck, Daphnee Brazeau, Amelie A Deshaies, Marie-Michele Briand, Charlotte Maschke

“…Phone assessments at 3, 6 and 12 months post-tACS, will measure long-term functional recovery, quality of life and caregivers’ burden.Ethics and dissemination Ethical approval for this study has been granted by the Research Ethics Board of the CIUSSS du Nord-de-l’Île-de-Montréal (Project ID 2021–2279). …”
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AI prediction model for endovascular treatment of vertebrobasilar occlusion with atrial fibrillation by Zhi-Xin Huang, Andrea M. Alexandre, Alessandro Pedicelli, Xuying He, Quanlong Hong, Yongkun Li, Ping Chen, Qiankun Cai, Aldobrando Broccolini, Luca Scarcia, Serena Abruzzese, Carlo Cirelli, Mauro Bergui, Andrea Romi, Erwah Kalsoum, Giulia Frauenfelder, Grzegorz Meder, Simona Scalise, Maria Porzia Ganimede, Luigi Bellini, Bruno Del Sette, Francesco Arba, Susanna Sammali, Andrea Salcuni, Sergio Lucio Vinci, Giacomo Cester, Luisa Roveri, Xianjun Huang, Wen Sun

“…Novel findings include nonlinear relationships between dyslipidemia, stroke severity, and functional recovery. The developed predictive algorithm (AUC 0.719 internally, 0.684 externally) offers a more sophisticated risk stratification tool, potentially guiding personalized treatment strategies in high-complexity VBAO patients with atrial fibrillation.…”
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Curcumin administration alleviates seminal vesicle damage in type 1 diabetic rats by promoting AQP8 expression through AR activation by Dawei Ni, Kun Liu, Ning Wu, Bin You, Baibing Yang, Wei Wu, Yutian Dai

“…The curcumin group, which was subjected to a one-month-long intervention after STZ-induced diabetes onset, exhibited significant histological and functional recovery. Haematoxylin‒eosin (HE) staining revealed disordered seminal vesicle tissue structures and decreased epithelial cell height in diabetic rats, which was partially restored after curcumin treatment. …”
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Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review by Yaoguang Guo, Sihan Hu, Sihan Hu, Shiman Luo, Lang Tu, Yao Tang, Fang Zeng, Fang Zeng, Fang Zeng

“…Improvements were also noted in neurological deficit scores [MD = −0.59, 95%CI (−0.92, −0.27), p < 0.05] and modified Neurological Severity Scores (mNSS) [MD = -5.68, 95%CI (−7.41, −3.95), p < 0.05], highlighting functional recovery. While the analysis showed no significant effect on caspase-3 densities [MD = −0.39, 95%CI (−0.79, 0.02), p > 0.05], a notable increase in Bcl-2 densities suggested an anti-apoptotic mechanism [MD = −0.73, 95%CI (−1.68, 0.21), p > 0.05]. …”
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Validity, Accuracy, and Safety Assessment of an Aerobic Interval Training Using an App-Based Prehabilitation Program (PROTEGO MAXIMA Trial) Before Major Surgery: Prospective, Inter... by Sara Fatima Faqar Uz Zaman, Svenja Sliwinski, Lisa Mohr-Wetzel, Julia Dreilich, Natalie Filmann, Charlotte Detemble, Dora Zmuc, Felix Chun, Wojciech Derwich, Waldemar Schreiner, Wolf Bechstein, Johannes Fleckenstein, Andreas A Schnitzbauer

“…Multimodal prehabilitation can enhance functional recovery after surgery and reduce postoperative complications. …”
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The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression by Callan L. Attwell, Inés Maldonado-Lasunción, Ruben Eggers, Bastiaan A. Bijleveld, Ward M. Ellenbroek, Natascha Siersema, Lotte Razenberg, Dédé Lamme, Nitish D. Fagoe, Ronald E. van Kesteren, August B. Smit, Joost Verhaagen, Matthew R. J. Mason

“…In vivo, KLF7/MEF2, but not ATF3/KLF7/MEF2 or KLF7 or MEF2 alone, promoted axonal sprouting into the dorsal column lesion site and led to improved functional recovery. Gene expression profiling revealed that unexpectedly, the MEF2-VP16 construct used had little transcriptional activity in vivo, suggesting additional steps may be required to achieve full MEF2 activity. …”
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