Actin Alpha 2 (ACTA2) Downregulation Inhibits Neural Stem Cell Migration through Rho GTPase Activation by Ji Zhang, Xuheng Jiang, Chao Zhang, Jun Zhong, Xuanyu Fang, Huanhuan Li, Fangke Xie, Xiaofei Huang, Xiaojun Zhang, Quan Hu, Hongfei Ge, Anyong Yu

“…The present study might enrich the basic knowledge of ACTA2 in NSC migration and open an avenue for enhancing NSC migration potential, subsequently providing an intervention target for functional recovery after CNS injury.…”
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The effect of thermoelectric craniocerebral cooling device on protecting brain functions in post-cardiac arrest syndrome by Aydın Nadir, Deniz Kara, Ayda Turkoz

“…Neurological outcomes were favorable, with 62.5% of patients achieving CPC scores of 1 or 2, indicating functional recovery and independence. In contrast, CPC scores of 3 or higher were observed in 37.5% of patients, reflecting varying degrees of disability. …”
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Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord inju... by Shiming Li, Jianfeng Li, Guoliang Chen, Tao Lin, Penghui Zhang, Kuileung Tong, Ningning Chen, Shaoyu Liu

“…We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury. While exosomes are recognized as playing a pivotal role in neural stem cells exocrine function, their precise function in spinal cord injury remains unclear. …”
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The Neurodevelopmental Dynamics of Multilingual Experience During Childhood: A Longitudinal Behavioral, Structural, and Functional MRI Study by Pasquale Anthony Della Rosa, Gerda Videsott, Virginia Maria Borsa, Eleonora Catricalà, Nicolò Pecco, Federica Alemanno, Matteo Canini, Andrea Falini, Rita Franceschini, Jubin Abutalebi

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Effects of home-based mirror therapy and cognitive therapeutic exercise on the improvement of the upper extremity functions in patients with severe hemiparesis after a stroke: a pr... by Josefa Gonzalez-Santos, Raul Soto-Camara, Paula Rodriguez-Fernández, Maria Jimenez-Barrios, Jeronimo Gonzalez-Bernal, Carla Collazo-Riobo, Maha Jahouh, Yolanda Bravo-Anguiano, Jose M Trejo-Gabriel-Galan

“…The objective of this study is to evaluate which of these techniques, MT and CTE, combined with task-oriented training, is more effective in functional recovery and movement patterns of the upper extremities in patients with severe hemiparesis after a stroke.Methods and analysis This is a home-based, single-blind, controlled, randomised clinical trial with three parallel arms, including 154 patients who had a stroke aged above 18 years. …”
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Pretreatment With Fragments of Substance-P or With Cholecystokinin Differentially Affects Recovery From Sub-Total Nigrostriatal 6-Hydroxydopamine Lesion by S. Nikolaus, J. P. Huston, R. K. W. Schwarting

“…Furthermore, our previous work in the rat showed that either pre- or post-lesion treatment with substance P can promote functional recovery in cases of partial nigrostriatal dopamine lesions. …”
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Intraoperative Local Administration of Platelet-Rich Plasma (PRP) during Neurolysis Surgery for the Treatment of Digital Nerve Crush Injury by Akira Ikumi, Yuki Hara, Eriko Okano, Sho Kohyama, Norihito Arai, Yu Taniguchi, Hisashi Sugaya, Tomokazu Yoshioka, Akihiro Kanamori, Masashi Yamazaki

“…Postoperatively, early neuropathic pain relief and good functional recovery were obtained with no PRP-related adverse events. …”
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Applying 3D‐Printed Porous Ti6Al4V Prostheses to Repair Osteomyelitis‐Induced Partial Bone Defects of Lower Limbs: Finite Element Analysis and Clinical Outcomes by Bingchuan Liu, Qizhao Tan, Zhengguang Wang, Guojin Hou, Caimei Wang, Yun Tian

“…Conclusions 3D‐printed porous Ti6Al4V prostheses effectively restore anatomical integrity and optimize stress conduction in lower limbs, resulting in substantial functional recovery. This innovative approach shows promise for wider clinical adoption and warrants further investigation in medical practice.…”
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Extracorporeal Shockwave Therapy Reduces Pain and Improves Internal Rotation after Arthroscopic Capsular Release: A Randomized Clinical Trial by Zifan Lin, Hong Shao, Jun Chen, Wei Yao, Chang Liu, Zhengbiao Jin, Yunxia Li

“…To investigate the effect of ESWT on short-term functional recovery after arthroscopic capsular release (ACR). …”
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Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial. by Menglu Ouyang, Anila Anjum, Francisca Gonzalez Mc Cawley, Mohammad Wasay, Lu Ma, Xin Hu, Xiaoying Chen, Alejandra Malavera, Xi Li, Paula Muñoz Venturelli, H Asita de Silva, Nguyen Huy Thang, Kolawole W Wahab, Jeyaraj D Pandian, Octavio M Pontes-Neto, Carlos Abanto, Venessa Cano-Nigenda, Antonio Arauz, Chao You, Stephen Jan, Lili Song, Craig S Anderson, Hueiming Liu, INTERACT3 Investigators

“…The third, stepped-wedge, cluster-randomized, Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3), has shown that a goal-directed multi-faceted Care Bundle incorporating protocols for the management of physiological variables was safe and effective for improving functional recovery in a broad range of patients with acute intracerebral hemorrhage (ICH). …”
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Adenosine A2A receptor activation is necessary to gate the TrkB-dependent intramuscular nerve sprouting during muscle reinnervation after a nerve crush by Michael Di Palma, Davide Lattanzi, Patrizia Ambrogini, Stefano Sartini

“…Since motor nerve terminals co-express TrkBs and A2ARs and depolarizing conditions increase muscle release of BDNF and adenosine, we examined whether A2ARs activation could recapitulate the functional recovery benefits of intermittent exercise after a nerve crush. …”
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Electrophysiological Predictors of Clinical Outcome in Traumatic Neuropathies: A Multicenter Prospective Study by Palma Ciaramitaro, Mauro Mondelli, Eugenia Rota, Bruno Battiston, Arman Sard, Italo Pontini, Giuliano Faccani, Giuseppe Migliaretti, Aristide Merola, Dario Cocito, Italian Network for Traumatic Neuropathies

“…Serial NCS assessments predict the functional recovery in TN, increasing the accuracy of peripheral nerves surgical decision-making process.…”
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Effectiveness of rehabilitation interventions in patients with colorectal cancer: an overview of systematic reviews by Mengzhe Yang, Bhasker Amatya, Sana Malik, Krystal Song, Stefanie Marcella, Catherine Voutier, Fary Khan

“…The findings suggest: moderate-quality evidence for exercise interventions for improving physical fitness and quality of life; high-quality evidence for nutritional interventions in reducing postoperative infections; high-quality evidence for multimodal prehabilitation for improved preoperative functional capacity; moderate-quality evidence for nutritional interventions for improving humoral immunity, reducing inflammation, and length of stay; moderate-quality evidence for acupuncture in improving gastrointestinal functional recovery; psychosocial interventions in improving short-term quality of life and mental health, and lifestyle interventions for improved quality of life. …”
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The Morphofunctional Effect of the Transplantation of Bone Marrow Stromal Cells and Predegenerated Peripheral Nerve in Chronic Paraplegic Rat Model via Spinal Cord Transection by Vinnitsa Buzoianu-Anguiano, Sandra Orozco-Suárez, Elisa García-Vences, Sara Caballero-Chacón, Gabriel Guizar-Sahagún, Luis Chavez-Sanchez, Israel Grijalva

“…Functional recovery following spinal cord injury (SCI) is limited by poor axonal and cellular regeneration as well as the failure to replace damaged myelin. …”
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Effect of Spine Nerves Muscle Stimulation Combined with Scalp Acupuncture on Shoulder-hand Syndrome after Early Stroke by Huazhong YANG, Yongsheng ZHOU, Haipeng JIA, Qingjun YANG, Lingjuan RAO

“…It can provide a scientific basis for accelerating the resolution of pain and provide favorable conditions for functional recovery of upper limbs and hands as well as the recovery of daily living ability, which is worthy of popularization and application.…”
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Outcomes of Open Reduction and Modified McLaughlin’s Procedure in Neglected Posterior Shoulder Dislocation by Vikas, Jatin Prakash, Karan Maggo, Jujhar Singh, Ankesh Jain, Naval Bhatia

“…The procedure leads to significant improvements in Constant Shoulder Scores, pain relief, functional recovery, and shoulder stability. Early diagnosis and timely surgical intervention are crucial in achieving successful outcomes for neglected shoulder dislocations. …”
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Clinical validation of an individualized auto-adaptative serious game for combined cognitive and upper limb motor robotic rehabilitation after stroke by Ioannis Doumas, Thierry Lejeune, Martin Edwards, Gaëtan Stoquart, Yves Vandermeeren, Bruno Dehez, Stephanie Dehem

“…Robot-assisted therapy (RAT) and serious games could be used to enhance functional recovery by providing simultaneous motor and cognitive rehabilitation. …”
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Perioperative nursing based on enhance recovery after surgery for pediatric patients undergoing modified artificial partial knee-joint prosthesis replacement for osteosarcoma aroun... by NONG Yuanxia (农源夏), CHEN Jian (陈剑), YANG Shuyun (杨舒云)

“…ERAS-based nursing intervention is effective to improve the functional recovery of knee joint and reduce the postoperative complications in modified artificial partial knee-joint prosthesis replacement for osteosarcoma around the knee joint. …”
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Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis by Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu

“…LF-rTMS as an add-on therapy significantly improved upper limb functional recovery especially the hand after stroke, probably through rebalanced cortical excitability of both hemispheres. …”
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Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

“…Conclusion: The included studies collectively suggest a strong neuroprotective activity, with the biochemical enhancements contributing to better neurological health and functional recovery. Hence, the reported plants could be explored as options in complementary and alternative medicine following a thorough examination of their active ingredient and mechanism of action.…”
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