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1141
Insight in Hypoxia-Mimetic Agents as Potential Tools for Mesenchymal Stem Cell Priming in Regenerative Medicine
Published 2022-01-01“…These agents are not studied so wildly as hypoxia but, considering the low cost and ease of use, are believed to find application as pretreatment of many diseases such as ischemic heart disease and myocardial fibrosis and promote cardiac and cartilage regeneration. …”
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1142
Pediatric hypertrophic cardiomyopathy caused by a novel TNNI3 variant
Published 2024-03-01“…The patient exhibited progressive myocardial fibrosis, left ventricular remodeling, and life-threatening arrhythmias. …”
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1143
Profile of STING agonist and inhibitor research: a bibliometric analysis
Published 2025-02-01“…BackgroundSTING is a core signaling hub molecule in the innate immune system, involved in various diseases, including infectious diseases, autoimmune diseases, tumors, aging, organ fibrosis, and neurodegenerative diseases. Its activation has shown great potential in anti-tumor and anti-infective therapies, with STING agonists emerging as a promising approach in cancer immunotherapy in recent years. …”
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1144
Amoebic Liver Abscess and Indigenous Alcoholic Beverages in the Tropics
Published 2018-01-01“…Late-stage liver disease with fibrosis seems to be protective for the development of ALA. …”
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1145
A Comprehensive Updated Review of Pharmaceutical and Nonpharmaceutical Treatment for NAFLD
Published 2016-01-01“…Surgery and weight loss medication are effective means of weight loss but can potentially worsen NASH related fibrosis. Other agents such as n-3 polyunsaturated fatty acids, probiotics, and pentoxifylline along with herbal agent such as milk thistle as well as daily intake of coffee have shown potential benefits, but further well organized studies are definitely warranted. …”
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1146
Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway
Published 2025-01-01“…The degree of renal fibrosis was observed using Masson and PAS staining. …”
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1147
The CYP4/20-HETE/GPR75 axis in the progression metabolic dysfunction-associated steatosis liver disease (MASLD) to chronic liver disease
Published 2025-01-01“…IntroductionMetabolic-dysfunction-associated steatosis liver disease (MASLD) is a progressive liver disease from simple steatosis, steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. …”
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1148
Single-Nucleus RNA Sequencing Reveals Cellular Transcriptome Features at Different Growth Stages in Porcine Skeletal Muscle
Published 2025-01-01“…We also constructed differentiation trajectories for FAPs and adipocytes, revealing that FAPs in 245-day-old pigs differentiated more toward fibrosis, a characteristic reminiscent of the high prevalence of skeletal muscle fibrosis in aging humans. …”
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1149
Difficulties of Bariatric Surgery after Abdominoplasty
Published 2014-01-01“…During laparoscopy, the main problems of patients who have undergone previous abdominoplasty are inadequate pneumoperitoneum secondary to fibrosis and reconstructed anatomic landmarks for trocar placement. …”
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1150
Molecular Basis for Mucolytic Therapy
Published 1995-01-01“…Airway obstruction in cystic fibrosis (CF) lung disease is accompanied by the accumulation of thick and viscous secretions resulting from chronic infection and inflammation, promoting recurrent exacerbations. …”
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1151
COMMON CAUSES OF LIMITED MOUTH OPENING ANDITS MANAGEMENT APPROACH AMONG DENTISTS IN KARACHI
Published 2024-10-01“…The three most common causes of trismus according to the present study came out to be oral submucosal fibrosis (26.7%), infections (24.0%), and trauma (15.0%), respectively. …”
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1152
Primary sclerosing cholangitis
Published 2008-01-01“…Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of the bile ducts, resulting in end-stage liver disease and reduced life expectancy. …”
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1153
Morfea mamaria. Presentación de un caso
Published 2017-06-01“…La esclerodermia localizada es la forma localizada cutánea de esclerodermia, caracterizada por una fibrosis que se manifiesta en forma de placas o bandas cutáneas escleróticas infiltradas al tacto. …”
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1154
Injectable agents for the induction of Peyronie’s disease in model rats: a comparative study
Published 2025-01-01“…In conclusion, fibrin, STS + TGF-β1, and POL + TGF-β1 all induced PD with a certain degree of penile curvature and histological fibrosis in rats. The POL + TGF-β1 combination offered comparatively greater safety and clinical relevance and may have the greatest potential for PD research using model rats.…”
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1155
Combined Application of Bevacizumab and Mitomycin C or Bevacizumab and 5-Fluorouracil in Experimental Glaucoma Filtration Surgery
Published 2018-01-01“…In animal experiments, the observation of filtering bleb survival, hematoxylin and eosin and Masson staining of filtering bleb scars, and mRNA expression levels of fibrosis markers in filtering blebs showed that combined BVZ and 5-Fu had a better antiscarring effect compared with single drugs; however, the antiscarring effect of combined BVZ and MMC was not significantly different from MMC. …”
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1156
The Role of mTOR Inhibitors in Liver Transplantation: Reviewing the Evidence
Published 2014-01-01“…Finally, we discuss evidence that mTOR inhibitors may have benefits in the oncology setting and in relation to HCV-related allograft fibrosis, metabolic syndrome, and neurotoxicity.…”
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1157
A Severe Case of Drug-Induced Liver Injury after Gemcitabine Administration: A Highly Probable Causality Grading as Assessed by the Updated RUCAM Diagnostic Scoring System
Published 2020-01-01“…Moreover, on the liver biopsy, there were histological findings of mild-to-moderate portal hepatitis, eosinophilia, bile duct injury, and mild perisinusoidal fibrosis, suggesting drug damage.…”
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1158
A Rare Case of Carotid Web Presenting with Ischemic Stroke in a Young Woman and a Brief Review of the Literature
Published 2018-01-01“…It is histologically defined as atypical fibromuscular dysplasia (FMD), with abnormal fibrosis and smooth muscle cell hyperplasia in the tunica intima. …”
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1159
From an allergic reaction to a superior vena cava syndrome
Published 2024-01-01“…The venous obstruction may be due to compression, invasion, thrombosis, or fibrosis of the SVC. SVCS can be the initial presentation of a previously undiagnosed tumor in up to 60% of cases. …”
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1160
Recognizing Immunoglobulin G4-Related Overlap Syndromes in Patients with Pancreatic and Hepatobiliary Diseases
Published 2008-01-01“…It is now recognized that a spectrum of overlap syndromes associated with increased IgG4 and biopsy evidence of IgG4-producing plasma cells, which has now been convincingly linked with cholangitis, autoimmune hepatitis, Sjögren’s syndrome, nephritis and retroperitoneal fibrosis. Collectively, this disease cluster is referred to as IgG4-related systemic disease. …”
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