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4541
Identification of Lauric Acid as a Potent Sodium Channel NaV1.5 Blocker from Compound Chinese Medicine Wenxin Keli
Published 2025-01-01“…Mechanistically, lauric acid acts on the fast inactivation of NaV 1.5 alter electrophysiology conduction of hiPSC-derived cardiomyocytes and contribute to the antiarrhythmic effect of WXKL.Conclusion: Lauric acid is a potent blocker for sodium channel NaV 1.5 and alleviates arrhythmia via inhibiting INa. …”
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4542
Research progress of continuous care of patients after percutaneous coronary intervention (经皮冠状动脉介入治疗术后患者延续性护理的研究进展)
Published 2024-03-01“…Percutaneous coronary intervention (PCI) is a non-surgical, invasive procedure with advantages of minimal incision and fast recovery in the treatment of coronary heart disease. …”
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4543
Multi-observatory Study of Young Stellar Energetic Flares (MORYSEF): No Evidence for Abnormally Strong Stellar Magnetic Fields after Powerful X-Ray Flares
Published 2025-01-01“…This requirement for giant dipolar loops aligns with MHD predictions of strong dipoles supported by polar magnetic surface active regions in fast-rotating, fully convective stars.…”
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4544
Perencanaan Coverage Jaringan 5G Berdasarkan Propagasi Rugi Rugi Lintasan dan Shadowing
Published 2021-03-01“…Abstract The demand for and the need for network services that are more inclined towards fast and mobile data services, encourages the need for the application of 5G technology. 5G technology has not been implemented in Indonesia. …”
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4545
Rational composition engineering for high‐quality Pb–Sn photodetector toward sensitive near‐infrared digital imaging arrays
Published 2025-01-01“…Consequently, it demonstrates a −3 dB bandwidth of 2.23 × 104 Hz, fast rise and decay times of 61 and 30 μs, respectively, and a linear dynamic range (LDR) of 155 dB. …”
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4546
Komparasi Machine Learning Berbasis Pso Untuk Prediksi Tingkat Keberhasilan Belajar Berbasis E-Learning
Published 2023-04-01“…Abstract The development of the field of technology has a very fast development aspect. our research has the aim of transmitting knowledge about machine learning which has become so popularly used until now, in this study how to get attribute selection features and get predictive results from learning at universities or educational institutions that apply learning by distance learning methods or e-learning. …”
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4547
Imaging Spectroscopy: Earth and Planetary Remote Sensing with the PSI Tetracorder and Expert Systems from Rovers to EMIT and Beyond
Published 2024-01-01“…Four abundance models are presented, each with increasing sophistication, that are computationally fast on imaging spectrometer data and use Tetracorder identifications to produce maps of mineral abundances. …”
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4548
Topologically constrained DNA-mediated one-pot CRISPR assay for rapid detection of viral RNA with single nucleotide resolutionResearch in context
Published 2025-02-01“…Summary: Background: The widespread and evolution of RNA viruses, such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), highlights the importance of fast identification of virus subtypes, particularly in non-laboratory settings. …”
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4549
In situ training of an in-sensor artificial neural network based on ferroelectric photosensors
Published 2025-01-01“…Our FE-PS exhibits self-powered, fast (<30 μs), and multilevel (>4 bits) photoresponses, as well as long retention (50 days), high endurance (109), high write speed (100 ns), and small cycle-to-cycle and device-to-device variations (~0.66% and ~2.72%, respectively), all of which are desirable for the in situ training. …”
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4550
Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae
Published 2024-12-01“…In mouse models, ramR L58P and F165L mutants showed lower bacterial burden in organs (spleen, lung, and kidney) 6 h post‐infection, and are fast cleared in 48 h. Furthermore, despite lower intracellular bacterial loads, ramR L58P and F165L mutants induce heightened pro‐inflammatory cytokine responses in macrophages and elevate systemic cytokine levels (interleukin [IL]2, IL4, IL6, IL12, interferon‐α, and interferon‐γ) in human blood co‐culture experiments. …”
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4551
Carbon storage potential and influencing factors of mangrove plantation in Kaozhouyang, Guangdong Province, South China
Published 2025-01-01“…In addition, suitable habitat conditions (landward) and fast-growing species (Sonneratia apetala) are more beneficial to carbon accumulation. …”
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4552
Immunosuppressive therapy and nutritional diseases of patients after kidney transplantation: a systematic review
Published 2025-01-01“…Another aspect was the use of slow and fast Tacrolimus metabolizers. There was no difference observed in phase angle, visceral fat area, lean body mass index, and the proportion of lean mass as a percentage of total body mass between them. …”
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4553
Enhancing deep learning methods for brain metastasis detection through cross-technique annotations on SPACE MRI
Published 2025-02-01“…HAQ alone achieves about 40% of the performance improvements seen with SPACE images as input, allowing for fast and accurate, fully automated detection of small (< 1 cm) BMs. …”
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4554
Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis
Published 2025-01-01“…It is characterized by a fast and prolonged loss in renal function arising from numerous etiologies and pathogenic pathways. …”
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4555
SO<sub>2</sub> emissions derived from TROPOMI observations over India using a flux-divergence method with variable lifetimes
Published 2025-02-01“…<p>The rapid development of the economy and the implementation of environmental policies adapted in India have led to fast changes of regional SO<span class="inline-formula"><sub>2</sub></span> emissions. …”
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4556
Is the freezing index a valid outcome to assess freezing of gait during turning in Parkinson’s disease?
Published 2025-01-01“…Turning on the spot for one minute in alternating directions (360 turn) while performing a cognitive dual-task (DT) is a fast and sensitive way to provoke FOG. The FOG-index is a widely used wearable sensor-based algorithm to quantify FOG severity during turning. …”
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4557
Noel Hernández Rodríguez, scalpel in hand plastic surgeon
Published 2024-04-01“…He will remain in the memory of those who knew him as the competent, fast and dynamic surgeon he always was, as the man of wisdom and emotional intelligence, the doctor who was capable of contributing to his profession with achievements reflected in the history of public health in Sancti Spíritus province. …”
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4558
Multi-objective optimal offloading decision for cloud-edge collaborative computing scenario in Internet of vehicles
Published 2022-06-01“…However,the characteristics of fast movement of vehicles in the Internet of vehicles make the conventional cloud-edge collaborative model not applicable. …”
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4559
Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus)
Published 2025-01-01“…It is an important economic fish species characterized by fast growth, temperature-dependent sex determination and the ability to breathe air. …”
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4560
Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age
Published 2025-01-01“…The acetylator statuses were homozygous fast (<i>n</i> = 3), heterozygous intermediate (<i>n</i> = 18), and homozygous slow (<i>n</i> = 2; unavailable in one patient). …”
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