Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive att... by José Hernández-Rodríguez, Fernando Martínez-Valle, Xènia Acebes, Carmen Alerany, Jordi Antón, Gonzalo Calvo, Marian Corral, Jordi Cruz, M. Antònia Mangues-Bafalluy, José Mateo, Josefa Rivera, Albert Salazar, Roser Francisco, Cristina Mallol, Rita Reig-Viader, Ariadna Tigri-Santiña, Assumpta Ricart, Francesc Palau

“…Results The Catalan Government healthcare model of XUECs for the comprehensive care for RDs is currently valid and adapted to the needs of PLWRD and their families since its strategic optimal and operational framework, and it is aligned with the European Reference Networks (ERNs) thematic areas. …”
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A rapid and simple clonality assay for bovine leukemia virus-infected cells by amplified fragment length polymorphism (AFLP) analysis by Tomoko Kobayashi, Sakurako Makimoto, Nagaki Ohnuki, Md Belal Hossain, M. Ishrat Jahan, Misaki Matsuo, Kazuhiko Imakawa, Yorifumi Satou

“…ABSTRACT Enzootic bovine leukosis (EBL), although eradicated in some European countries, is still the most common neoplastic disease of cattle, caused by the bovine leukemia virus (BLV). …”
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Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening by Georgina L Hollitt, Mark M Hassall, Owen M Siggs, Jamie E Craig, Emmanuelle Souzeau

“…The cohort was highly educated (42% university education), all were European and 50% were female. Numeracy (mean 2.1 ± 0.9, range 0 to 3), graph literacy (mean 2.8 ± 0.8, range 0 to 4) and genetic literacy (mean 24.2 ± 6.2, range − 20 to + 46) showed a range of levels. …”
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The ASK-16 motorized glider: an airborne eddy covariance platform to measure turbulence, energy, and matter fluxes by I. Wiekenkamp, A. K. Lehmann, A. Bütow, J. Hartmann, S. Metzger, S. Metzger, T. Ruhtz, C. Wille, M. Zöllner, T. Sachs, T. Sachs

“…Here, we introduce an airborne eddy covariance measurement platform based on an ASK-16 touring motor glider (TMG; also referred to as a power glider, hereafter referred to as motorized glider), which is equipped to measure the three-dimensional (3D) wind vector, and atmospheric conditions, and we derive airborne turbulent fluxes for the use of measurement campaigns over European landscapes. This study describes the measurement setup of the platform and explains the workflows that were used to calculate and calibrate the 3D wind vector, turbulent fluxes, and their associated source areas. …”
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Mobile-based in-home telerehabilitation compared with in-hospital face-to-face rehabilitation for elderly patients after total hip arthroplasty in China's level 1 trauma center: a... by Yang Zhou, Yiming Lyu, Qiaojie Wang, Yanhong Ma, Lihua Huang, Xin Zhang, Xin Zhang

“…BackgroundTelerehabilitation is gaining popularity in European and American countries, but whether it can be successfully implemented in China still lacks support from clinical studies.ObjectiveThis trial aimed to determine if a home-based telerehabilitation method is clinically noninferior to standard in-hospital face-to-face rehabilitation for elderly patients with total hip arthroplasty (THA) in China.MethodsThis multicenter randomized controlled trial was conducted from January 2021 to June 2022 at The First Rehabilitation Hospital in Shanghai, Shanghai Jiao Tong University affiliated Sixth People's Hospital and Shanghai Tongji University affiliated Tenth People's Hospital. …”
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Suspicion, screening, and diagnosis of wild‐type transthyretin amyloid cardiomyopathy: a systematic literature review by Katrine Bay, Finn Gustafsson, Michael Maiborg, Anne Bagger‐Bahnsen, Anne Mette Strand, Trine Pilgaard, Steen Hvitfeldt Poulsen

“…Systematic screening was mentioned in 16 articles, 10 of which suggested specific at‐risk populations for screening. The European Society of Cardiology recommends to screen patients with a wall thickness ≥12 mm and heart failure, aortic stenosis, or red flag symptoms, especially if they are >65 years. …”
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Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease by Zhihao Qi, Quan Li, Shuhua Yang, Chun Fu, Burong Hu

“…<b>Methods:</b> Summary statistics from expression quantitative trait loci (eQTL), DNA methylation QTL (mQTL), and protein QTL (pQTL) on European descent were included. The GWAS summarized data for IBD and its two subtypes, Crohn’s disease (CD) and ulcerative colitis (UC), were acquired from the FinnGen study. …”
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Predictive modeling to evaluate long-term treatment effectiveness of darvadstrocel in patients with complex perianal fistulas in Crohn’s disease by Chitra Karki, Gary Hantsbarger, Erika Turkstra, Elisabetta Fenu, Ken Genenz, Inmaculada Gilaberte, Julián Panés

“…ADMIRE-CD was conducted in 49 hospitals in 7 European countries and Israel. INSPECT used data from the ADMIRE study. …”
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Interleukin-12 Inhibits Tumor Growth and Metastasis Promoted by Tumor-Associated Mesenchymal Stem Cells in Triple-Negative Breast Cancer by Babak Jahangiri, Zahra-Soheila Soheili, Elahe Asadollahi, Mehdi Shamsara, Vahid Shariati, Alireza Zomorodipour

“…The TA-MSCs RNA-seq dataset (PRJEB27694) was analyzed todetect elevated metastasis-associated oncogenes, downloaded from the European Nucleotide Archive database. Forvalidation of the RNA-seq data analysis, the expression levels of candidate oncogenes were evaluated in TA-MSCs,TNBC cells, and tumor tissue using RT-PCR.Results: TA-MSCs enhanced migration, invasion, and EMT of TNBC cells in vitro without affecting cell proliferation orapoptosis. …”
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Nailfold Capillaroscopy in Early Stages of Mixed Connective Tissue Disease in a Sample of Egyptian Patients by Yasser A Elmotaleb Gazar, Hesham Salah Hamoud, Sherif Mohamed Ismail

“…Methodology: This cross-sectional study included forty patients diagnosed with MCTD according to Alarcón-Segovia and Villareal criteria and twenty patients with confirmed systemic sclerosis according to the American College of Rheumatology and the European League against Rheumatism classification criteria for Systemic Sclerosis. …”
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The effect of sulthiame on potential biomarkers in moderate to severe obstructive sleep apnoea by Erik Hoff, Saliha Musovic, Ali M. Komai, Ding Zou, Christian Strassberger, Kaj Stenlöf, Ludger Grote, Jan Hedner

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Causal Association Between Obstructive Sleep Apnea and Migraine: A Bidirectional Mendelian Randomization Study by Wang YP, Wei HX, Hu YY, Zhang C, Niu YM

“…In addition, increased risk of migraine and migraine without aura on OSA occurrence were identified in the reverse analysis, but these results were subsequently negated with MVMR analysis.Conclusion: According to the current findings, there was a preliminary causal effect of OSA on MA among European descendants.Clinical Relevance: These findings suggest a potential causal effect of OSA on migraine and provide new insights to prevent and manage the two disorders.Keywords: obstructive sleep apnea, migraine, Mendelian randomization, causal effect…”
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Surfactant-derived protein type B: a new biomarker linked to respiratory failure and lung damage in mild to moderate SARS-CoV-2 pneumonia by Massimo Mapelli, Elisabetta Salvioni, Irene Mattavelli, Cristina Banfi, Stefania Ghilardi, Arianna Greco, Maria Luisa Biondi, Sara Rovai, Elisabetta Mancini, Sergio Harari, Piergiuseppe Agostoni

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Supplementary oxygen efficacy for chronic pulmonary disorders and exertion desaturation by Paraschos Archontakis Barakakis, Adam Wolfe, Andrei Schwartz, Gabriel J. Hernandez Romero, Vipul Gidwani, Shaylika Chauhan, Shinichi Arizono, Ralph J. Panos, Spyridon Fortis

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Changes in the visual analyzer occurring as a result of space flight by M.A. Valyakh, N.G. Baeva

“…<br> Over the past few years, NASA officers have repeatedly recorded changes in the visual organ of astronauts after long space missions, in particular, they manifested an optic nerve swelling, a reduction in the anterior-posterior axial length of the eye, a change in blood flow velocity, and hypermetropia. European scientists obtained similar data. Also, velvet-like exudates were ophthalmoscopically revealed and visual field loss was recorded. …”
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The development of the Cough Hypersensitivity Questionnaire for chronic cough by Barnaby Hirons, Peter S.P. Cho, Chris Krägeloh, Richard J. Siegert, Richard Turner, Katherine Rhatigan, Harini Kesavan, Ewan Mackay, Ha-Kyeong Won, Ju-Young Kim, Woo-Jung Song, Surinder S. Birring

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Surrogate-based model parameter optimization in simulations of the West African monsoon by M. Fischer, P. Knippertz, C. Proppe

“…As reference data, Integrated Multi-satellitE Retrievals for the Global Precipitation Measurement (GPM IMERG) mission are used for precipitation, and the ERA5 reanalysis data from the European Centre for Medium-Range Weather Forecasts are used for all other quantities. …”
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FEAR OF SOCIAL ALIENATION OF LOVE AS GENDER CHARACTERISTICS by V. V. Melnyk, L. І. Моzhovyi, I. A. Reshetova

“…The paper investigates the fear of alienation of love, not as an instinct or psychological experience, or as a social factor, but as a correlation between the functional types of fear and the peculiarities of social and cultural processes, and it acts as a dependence of the European societies on the various functional forms of fear of love that influence the processes of social transformations. …”
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The Shiism Dimension in Iran's Relations with Europe: The Example of Germany-France-United Kingdom by Orhan Karaoğlu

“…Its relationship with the Shiite communities here appears as an important element in Iran's relations with European countries in the context of foreign policy. …”
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Towards targeted cancer therapy: Synthesis, characterization, and biological activity of a new Cu(II)-ibuprofen-2,2′-dipyridylamine metal complex by Luís P.G. Monteiro, A. Gomes, C. Silva, Ricardo F. Mendes, Filipe A. Almeida Paz, Dmitry Chernyshov, J. Rocha, F. Martel, T.M. Santos, B.J.M. Leite Ferreira

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