Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival by Abel Sousa, Aurelien Dugourd, Danish Memon, Borgthor Petursson, Evangelia Petsalaki, Julio Saez‐Rodriguez, Pedro Beltrao

Get full text

CEN‐tools: an integrative platform to identify the contexts of essential genes by Sumana Sharma, Cansu Dincer, Paula Weidemüller, Gavin J Wright, Evangelia Petsalaki

Get full text

CellRegMap: a statistical framework for mapping context‐specific regulatory variants using scRNA‐seq by Anna S E Cuomo, Tobias Heinen, Danai Vagiaki, Danilo Horta, John C Marioni, Oliver Stegle

Get full text

Phosphoproteomic analyses reveal novel cross‐modulation mechanisms between two signaling pathways in yeast by Stefania Vaga, Marti Bernardo‐Faura, Thomas Cokelaer, Alessio Maiolica, Christopher A Barnes, Ludovic C Gillet, Björn Hegemann, Frank van Drogen, Hoda Sharifian, Edda Klipp, Matthias Peter, Julio Saez‐Rodriguez, Ruedi Aebersold

Get full text

Clustering phenotype populations by genome‐wide RNAi and multiparametric imaging by Florian Fuchs, Gregoire Pau, Dominique Kranz, Oleg Sklyar, Christoph Budjan, Sandra Steinbrink, Thomas Horn, Angelika Pedal, Wolfgang Huber, Michael Boutros

Get full text

Publisher Correction: Comprehensive evaluation of phosphoproteomic-based kinase activity inference by Sophia Müller-Dott, Eric J. Jaehnig, Khoi Pham Munchic, Wen Jiang, Tomer M. Yaron-Barir, Sara R. Savage, Martin Garrido-Rodriguez, Jared L. Johnson, Alessandro Lussana, Evangelia Petsalaki, Jonathan T. Lei, Aurelien Dugourd, Karsten Krug, Lewis C. Cantley, D. R. Mani, Bing Zhang, Julio Saez-Rodriguez

Get full text

An atlas of human kinase regulation by David Ochoa, Mindaugas Jonikas, Robert T Lawrence, Bachir El Debs, Joel Selkrig, Athanasios Typas, Judit Villén, Silvia DM Santos, Pedro Beltrao

Get full text

hu.MAP3.0: atlas of human protein complexes by integration of >25,000 proteomic experiments by Samantha N Fischer, Erin R Claussen, Savvas Kourtis, Sara Sdelci, Sandra Orchard, Henning Hermjakob, Georg Kustatscher, Kevin Drew

Get full text

SARS‐CoV‐2 infection remodels the host protein thermal stability landscape by Joel Selkrig, Megan Stanifer, André Mateus, Karin Mitosch, Inigo Barrio‐Hernandez, Mandy Rettel, Heeyoung Kim, Carlos G P Voogdt, Philipp Walch, Carmon Kee, Nils Kurzawa, Frank Stein, Clément Potel, Anna Jarzab, Bernhard Kuster, Ralf Bartenschlager, Steeve Boulant, Pedro Beltrao, Athanasios Typas, Mikhail M Savitski

Get full text

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges by Alvis Brazma

Get full text

Evolution and functional cross‐talk of protein post‐translational modifications by Pedro Beltrao, Peer Bork, Nevan J. Krogan, Vera van Noort

Get full text

Hiding Information using Replacement in Silent Mutation of DNA Sequences by Sadoon Abdullah, Ahmed Nori

“…The DNA sequence obtained from EBI location (European Bioinformatics Institute). Among the DNA molecule characters, one of the mutant ability types, that is the silent mutant, was choose to hide a secret message within the sequence. …”
Get full text

Using single‐cell genomics to understand developmental processes and cell fate decisions by Jonathan A Griffiths, Antonio Scialdone, John C Marioni

Get full text

The International Health Cohorts Consortium (IHCC) advances population health research and genomic discovery by John J. Connolly, Scott Sundseth, Grant M. Wood, Chisom Nwaneri, Geoffrey Ginsburg, Philip Awadalla, Michele Ramsay, Thomas Keane, Peter Goodhand, Adam S. Butterworth, Hakon Hakonarson

Get full text

The need for methodological pluralism in epidemiological modelling by Pieter Streicher, Alex Broadbent, Joel Hellewell

Get full text

Differential genetic interactions of yeast stress response MAPK pathways by Humberto Martin, Michael Shales, Pablo Fernandez‐Piñar, Ping Wei, Maria Molina, Dorothea Fiedler, Kevan M Shokat, Pedro Beltrao, Wendell Lim, Nevan J Krogan

Get full text

Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses by Aurelien Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Attila Gabor, Kristina B. Emdal, Vitor Vieira, Dorte B. Bekker‐Jensen, Jennifer Kranz, Eric.M.J. Bindels, Ana S.H. Costa, Abel Sousa, Pedro Beltrao, Miguel Rocha, Jesper V. Olsen, Christian Frezza, Rafael Kramann, Julio Saez‐Rodriguez

Get full text

The value of post radiotherapy prostate specific antigen dynamics for prostate cancer risk stratification models by Jane Shortall, Eliana Vasquez Osorio, Andrew Green, Kimberley Reeves, David Wong, Tanuj Puri, Peter Hoskin, Ananya Choudhury, Marcel van Herk, Alan McWilliam

Get full text

First island-wide, single-day soil collection study on Crete reveals environmental drivers of microbial diversity by Johanna B. Holm, Savvas Paragkamian, Mike Humphreys, Apaala Chatterjee, Stephanie Yarwood, Josh Gaimaro, Melanthia Stavroulaki, Dimitris Tsaparis, Manolis Plaitis, Panagiotis Kasapidis, Stelios Darivianakis, Georgios Kotoulas, Antonios Magoulas, Anastasis Oulas, Zacharias Kyrpiotakis, Pavlos Pavlidis, Petra ten Hoopen, Guy Cochrane, H. C. F. Wiebe Kooistra, Jason R. Schriml, Bronwen E. Schriml, Ilias Lagkouvardos, Panos Gkorezis, Neil Davies, Christine Laney, Lee Stanish, Granger Sutton, Scott Tighe, Ilene Karsch Mizrachi, Donovan Parks, Pelin Yilmaz, Chelsea Carey, Pier Buttigieg, Philip Goldstein, Evangelos Pafilis, Lynn M. Schriml

Get full text