Artificial intelligence-derived gut microbiome as a predictive biomarker for therapeutic response to immunotherapy in lung cancer: protocol for a multicentre, prospective, observat... by Ryo Toyozawa, Fumihiro Shoji, Takanori Yamashita, Fumihiko Kinoshita, Shinkichi Takamori, Takatoshi Fujishita, Kensaku Ito, Koji Yamazaki, Naoki Nakashima, Tatsuro Okamoto

“…Enrolment will begin in 2021, and the final analyses will be completed by 2024.Ethics and dissemination The study protocol was approved by the institutional review board of each participating centre in 2021 (Kyushu Cancer Center, IRB approved No. 2021-13, 8 June 2021 and Kyushu Medical Center, IRB approved No. 21-076, 31 August 2021). …”
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Digital intervention promoting physical activity among obese people (DIPPAO) randomised controlled trial: study protocol by Bruno Pereira, Martine Duclos, Alexandre Mazéas, Aïna Chalabaev, Marine Blond

“…A mixed-model approach will be used to analyse the change in outcomes over time.Ethics and dissemination The research protocol has been reviewed and approved by the Local Human Protection Committee (CPP Ile de France XI, No 21 004-65219). …”
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Prevalence and associations of anisometropia with spherical ametropia, cylindrical power, age, and sex, based on 134,603 refractive surgery candidates. by Mona Deuchert, Andreas Frings, Vasyl Druchkiv, Jakob Schweighofer, Sajjad Muhammad, Stephan Linke, Toam Katz

“…Our study was approved by the local ethics committee at the University in Duesseldorf (approval date: February 9, 2021) and conducted according to the tenets of the Declaration of Helsinki and Good Clinical Practices Guidelines. …”
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Mapping an evidence-based end-of-life care framework for older adults in Chinese nursing homes: protocol for a scoping review by Yuanyuan Zhao, Boon How Chew, Yuehua Tu, Eva Marie Gacasan

“…Qualitative data analysis will be performed using a framework method and thematic analysis, employing both inductive and deductive approaches, with three reviewers participating in the review process.Ethics and dissemination Ethical approval is not required because the data for this review is obtained from selected publicly available articles. …”
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Dosage of joint mobilisation for the management of rotator cuff-related shoulder pain: protocol for a scoping review by Steve Tumilty, Daniel C Ribeiro, Sizhong Wang, Cathy M Chapple, Dusty Quinn

“…We will summarise the results using descriptive statistics and qualitative thematic analysis.Ethics and dissemination Ethical approval is not required for this protocol. …”
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Forecasting models for leprosy cases: a scoping review protocol by Bruna Oliveira Ascef, Gustavo Laine Araújo de Oliveira, Carmelita Ribeiro Filha Coriolano, Haliton Alves De Oliveira Junior

“…The Prediction Model Study Risk of Bias Assessment Tool (PROBAST) will be used.Ethics and dissemination No ethical approval is required for this study. …”
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Content analysis of food and beverage marketing in global esports: sponsorships of the premier events, leagues, teams and players by Robin Ireland, John William Long, Sara Jordan Maksi, Francisco Javier López Frías, Travis D Masterson

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Efficacy of virtual reality techniques in cardiopulmonary resuscitation training: protocol for a meta-analysis of randomised controlled trials and trial sequential analysis by Jia Wang, Lu Zhang, Guo Chen, Li Du, Jianqiao Zheng, Xiaoqian Deng

“…Egger’s regression test and funnel plots will be used to assess the publication bias.Ethics and dissemination Ethical approval was not required for this systematic review protocol. …”
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Perceived racial discrimination, resilience, and oral health behaviours of adolescents with immigrant backgrounds. by Priyanka Saluja, Babak Bohlouli, Wendy Hoglund, Maryam Amin

“…This study aimed to examine the associations between perceived discrimination and oral health behaviours in adolescents with immigrant backgrounds and explore the potential moderating role of resilience on this association.<h4>Methods</h4>Ethical approval for this cross-sectional study was obtained from the University of Alberta Research Ethics Board. …”
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A multi-level meta-analysis of the relationship between decision-making during birth and postpartum mental health by Louisa Arnold, Marie Völkel, Jenny Rosendahl, Michael Rost

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Prevalence of HPV in a Peruvian Healthcare Network: A Descriptive Cross-Sectional Study by Jhajaira M. Araujo MSc, Maria Ramon-Cotrina Br, Rosa Quispe-Martinez MD, Mayra Rios-Rios Br, Maribel Quispe-Gonzaga Br, Carlos O. Saldaña-Reyes Br, Paula Medina PhD, Melanie Cornejo PhD, Joseph A. Pinto MSc, Richard Dyer MD

“…The study was approved by an independent research ethics committee in Peru. Results Of 68,714 women included in the study, the HPV prevalence was 14.21% (N = 9765, 95%CI:13.95%–14.47%). …”
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Patient Perspectives on Evolving Diverticulitis Treatment: An Assessment of Patient Willingness to Enroll in a Randomized Controlled Trial by Annie Altman-Merino, MD, Kemberlee Bonnet, MA, David Schlundt, PhD, Jesse Wrenn, MD, PhD, Wesley H. Self, MD, MPH, Elisa J. Gordon, PhD, MPH, Alexander T. Hawkins, MD, MPH

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Predominant polarity in bipolar affective disorder and its impact on cognition and quality of life by Shashank Bhardwaj, Deoraj Sinha, Ami Pawar, Astik Mane

“…Method: After Institutional Ethics Committee Approval and written informed consent, patients who were diagnosed with BPAD attending out-patient department of a tertiary care hospital in Mumbai were recruited. …”
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Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies by Greta Ullrich, Alexander Bäuerle, Lisa Maria Jahre, Katrin Paldán, Jana Rosemeyer, Chiara Kalaitzidis, Christos Rammos, Martin Teufel, Tienush Rassaf, Julia Lortz

“…Trial Registration: The study was registered at ClinicalTrials.gov under the identifier NCT05096637 on 27 October 2021 and was approved by the local ethics committee of the University of Duisburg-Essen (20-9157-BO).…”
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Effectiveness of interventions for the prevention of occupational violence against professionals in health services: a protocol for a systematic review by Caroline Vieira Cláudio Okubo, Renata Cristina Campos Pereira Silveira, Maria José Quina Galdino, Daiane Rubinato Fernandes, Aline Aparecida Oliveira Moreira, Júlia Trevisan Martins

“…The quality of the evidence and strength of the classification recommendations will be assessed by the Grading of Recommendations, Assessment, Development and Evaluation.Ethics and dissemination This review will not evaluate individual patient information and therefore does not require ethical approval. …”
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Readability and understandability of clinical research patient information leaflets and consent forms in Ireland and the UK: a retrospective quantitative analysis by Peter Doran, Eilish McAuliffe, Lydia O'Sullivan, Prasanth Sukumar, Rachel Crowley

“…The second aim was to compare these findings with best practice guidelines.Design Retrospective, quantitative analysis of clinical research PILs/ICFs provided by academic institutions, pharmaceutical companies and investigators.Setting PILs/ICFs which had received Research Ethics Committee approval in the last 5 years were collected from Ireland and the UK.Intervention Not applicable.Main outcome measures PILs/ICFs were evaluated against seven validated readability criteria (Flesch Reading Ease, Flesh Kincaid Grade Level, Simplified Measure of Gobbledegook, Gunning Fog, Fry, Raygor and New Dale Chall). …”
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The promise and challenges of Artificial Intelligence-Large Language Models (AI-LLMs) in obstetric and gynecology by Khanisyah Erza Gumilar, Ming Tan

“…This multidisciplinary teamwork is vital for upholding ethical norms and preserving patient dignity and respect. …”
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Supervised pulmonary tele-rehabilitation and individualized home-based pulmonary rehabilitation for patients with COPD, unable to participate in center-based programs. The protocol... by Christina Nielsen, Nina Godtfredsen, Stig Molsted, Charlotte Ulrik, Thomas Kallemose, Henrik Hansen

“…<h4>Trial registration</h4>The trial is registrered and approved by the Ethics Committee of The Capital Region of Denmark (H-22015777; 29.08.2022) and the Danish Data Protection Agency (P-2022-245-13101, 25.05.2022). …”
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Application of multifunctional pulse wave sphygmomanometer combined with constant temperature ice in patients with forearm hematoma after coronary intervention by Jimin Qiao, Yihang Shi, Kai Li, Xiaomin Zhu, Zhimei Wang

“…This approach effectively reduced pain, improved comfort levels, and enhanced compression-based hemostasis and reduction of swelling. Trial registration Ethics No.KY20210604-02-KS-01.…”
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Nurture-U student mental health longitudinal survey: a study protocol by Kate E Saunders, Samuel R Chamberlain, Jemima Dooley, Edward R Watkins, Liz Forty, Sarah Rees, Anne C Duffy, Anthony Quinn, Ellen Marshall, Lucy Dorey, Kevin A Matlock, Alexandra Newbold, Lucy J Robinson

“…Recruitment will target all students, with an emphasis on first-year students, to track their mental health trajectory from university entry through subsequent years.Ethics and dissemination Ethical approval has been obtained from relevant committees at each participating university. …”
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