Protocol for the impact of machine learning-based clinician decision support algorithims in perioperative care (IMAGINATIVE) in Singapore general hospital : a large prospective ran... by Marcus Ong, Hairil Rizal Abdullah, Ecosse Lamoureux, Elaine Lum, Gek Hsiang Lim, Tan Pei Yi Brenda, Celestine Loh

“…The primary outcome is to evaluate the effectiveness of the Machine Learning Clinical Decision Support (ML-CDS) algorithm in improving perioperative mortality rates when integrated into the clinical workflow.Ethics and dissemination The study has been approved by the SingHealth Centralised Institutional Review Board (CIRB Ref: 2023:2114) and is registered on ClinicalTrials.gov (trial number: NCT05809232). …”
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Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test by Hogir Mohammed Shukri Saadi, Ali Yahya Saeed

“…Biographies from each case were taken in a questionnaire form after approval by Research Ethics Committee of the college of medicine / Duhok university. …”
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Clinical application of oral Chinese Patent Medicines in ophthalmology: a scoping review protocol by Wei Zhou, Kai Xu, Ziyang Huang, Xiaoyu Li, Xing Liao, Lina Liang, Yamin Li, Qianqian Zuo

“…However, comprehensive evidence for using CPMs in ophthalmology is lacking.Aim We will apply the methodology of scoping review to systematically search and sort out the available evidence on oral CPMs for the treatment of eye diseases, identify the distribution of evidence in this field and provide a basis for clinical practice and medical decisions.Methods The scoping review will be implemented in the following seven steps: (1) defining the research question; (2) searching National Essential Medicines List (2018 edition), National Basic Medical Insurance, Work Injury Insurance and Maternity Insurance Drug Catalog (2020 edition) and Chinese Pharmacopoeia (2020 edition) for oral CPMs for the treatment of eye diseases; (3) searching Embase, Web of Science, PubMed, Cochrane Library, Chongqing VIP Chinese Scientific Journals Database, Chinese National Knowledge Infrastructure, Chinese Biomedical Literature Database and Wanfang Database for relevant literature published from inception to December 2021; (4) developing eligibility criteria; (5) screening the studies based on inclusion criteria; (6) extracting relevant data and lastly, (7) collating, summarising and reporting the results.Ethics and dissemination Since the scoping review aims at collecting data from publicly available publications, this study does not require ethical approval. …”
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Equity in Basic Medical Education accreditation standards: a scoping review protocol by Usman Mahboob, Muhammad Irfan, Neelofar Shaheen, Ahsan Sethi

“…The scoping review entails the collection and synthesis of literature and does not require ethical approval as per local regulations, as it does not involve primary data collection or interaction with human participants. …”
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Reflection to enhance dental students´ awareness of and comfort with uncertainty – an experimental study by Joséphine Brodén, Helena Fransson, Niklas Vareman, Maria Pigg

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Protocol for investigating astrocytic mitochondria in neurons of adult mice using two-photon microscopy by Jian Zhou, Fengling Du, Fan Zhang, Xianhui Zhang, Yuanyuan Wu, Lifang Zhang, Ping Liao, Tianqi Tu, Jianhua Peng, Tao Li, Yong Jiang

“…We then detail procedures for the preparation of a coverslip with a customized titanium ring and cranial window for two-photon microscopy scanning.For complete details on the use and execution of this protocol, please refer to Zhou et al. 1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Serum neurofilament heavy chains as a biomarker of neuronal damage in multiple sclerosis relapse by P. Beliaziūnas, R. Godelienė, L. Malcienė, V. Natkevičius, V. Gintauskienė, B. Šitkauskienė, M. Malciūtė

“…BE-2-73 was obtained from Kaunas Regional Biomedical Research Ethics Committee. Using random sampling we examined 28 patients with relapsing-remitting multiple sclerosis who were treated for relapse in the Multiple Sclerosis Centre of Klaipėda University Hospital. …”
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Mapping the landscape and evidence of cross-sectoral collaboration models targeting individuals referred for assessment of attention-deficit hyperactivity disorder or autism spectr... by Niels Bilenberg, Pernille Tanggaard Andersen, Rikke Kirstine Kristensen, Emilie Dalsgaard Milling, Julie Dalgaard Guldager

“…Results will be synthesised into descriptive tables, providing a comprehensive mapping of existing models and emphasising implementation feasibility.Ethics and dissemination Ethical approval is not required for this protocol since it involves the review of existing literature without the involvement of human participants or personal data. …”
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Single postoperative infusion of zoledronic acid to improve patient-reported outcome after hip or knee replacement: study protocol for a randomised, controlled, double-blinded clin... by Jonas Ranstam, Jörg Schilcher, Ewa Roos, Jonathan Brandt, Håkan Ledin, Per Aspenberg

“…A total of 1000 patients will be included in the study.Ethics and dissemination The study has been approved by the Regional Ethical Review Board in Linköping (DNR 2015/286-31). …”
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Challenges in Burns Management in a Tertiary Care Center in Albania by Vladimir Filaj, Ester Tabaku, Ina Kola, Ferdiola Gjonaj, Vilma Tafilaj, Henri Drinjak

“…Formal approval was obtained from the Ethics Committee of Mother Teresa Hospital. The data were recorded in Excel and analyzed using the SPSS statistics program. …”
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Non-pharmaceutical interventions and epigenetic aging in adults: Protocol for a scoping review. by Alina Liebich, Shenglin Zheng, Theresa Schachner, Jacqueline Mair, Mia Jovanova, Falk Müller-Riemenschneider, Tobias Kowatsch

“…This review will synthesize information from available publications and does not require further ethical approval.<h4>Registration details</h4>Open Science Framework https://doi.org/10.17605/OSF.IO/FEHNB.…”
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Moral and exhausting distress working in the frontline of COVID-19: a Swedish survey during the first wave in four healthcare settings by Mia Svantesson, Lars Sandman, Linda Durnell, Erik Hammarström, Gustav Jarl

“…A lesson for management is that ethics support should first include acknowledgement of self-concern and mitigation of guilt before any structured ethical reflection. …”
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Does welfare technology contribute to security, activity, participation and independence within municipal elder care? A qualitative study protocol by Ingrid Hellström, Johannes Österholm, Åsa Larsson Ranada, Katarina Baudin, Vedrana B Baric

“…Data will be collected through semistructured interviews with different stakeholders—(a) older persons, (b) significant others, (c) staff and (d) decision-makers (ie, local politicians and local governmental officials)—in organisations within municipal elder care that use WT.Ethics and dissemination The study is approved by the Swedish Ethical Review Authority (Dnr 2023-07203-01). …”
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Applicability of TB-LAMP test for diagnosis of pulmonary TB among HIV-positive individuals by B. Muriithi, M.M. Bundi, T. Moriyasu, A. Ahmed, M. Mwamzuka, M. Karama, S. Kaneko

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Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis by Xin Wang, Ying Wang, Fenghua Zhou, Minxing Gao, Lingyuan Xu, Heying Wang, Jinan Song, Xiaoqiu Yang

“…Next, quantitative or qualitative, subgroup and sensitivity analyses of the included literature data will be performed as appropriate.Ethics and dissemination Ethical approval is not required for this systematic review as no primary data collection will be required. …”
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Early childhood constraint therapy for sensory/motor impairment in cerebral palsy: a randomised clinical trial protocol by Garey Noritz, Olena Chorna, Jill Heathcock, Alexandra Key, Helen Carey, Ellyn Hamm, Mary Ann Nelin, Micah Murray, Amy Needham, James C Slaughter, Nathalie L Maitre

“…The research material collected will be in the form of data from high-density array event-related potential scan, standardised assessment scores and motion analysis scores.Ethics and dissemination The study protocol was approved by the Institutional Review Board. …”
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Morphometric Effects of Testosterone Supplementation on Certain Extremity Bones in Young Swim-Trained Rats by Abdullah Kılcı, Sefa Lok

“…Although some athletes think that prohibited agents used as AAS affect performance positively, these agents should not be used because of their adverse effects on athletes’ health and because they are against sports ethics.…”
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Traditional Chinese medicine injections for heart failure: a protocol for systematic review and network meta-analysis of randomised controlled trials by Shanshan Lin, Qingyang Shi, Fengwen Yang, Xianliang Wang, Jingyuan Mao

“…Therefore, the study does not require ethical approval. The results will eventually be published in a peer-reviewed journal and disseminated at relevant conferences.PROSPERO registration number CRD42020166900.…”
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Impact of the COVID-19 pandemic on cerebral venous sinus thrombosis in China: a comparative study by Xiaoming Zhang, Kun Fang, Duo Lan, Xiangqian Huang, Xunming Ji, Ran Meng, Da Zhou

“…Trial registration This study protocol was reviewed and approved by the ethics committee of Xuanwu Hospital, Capital Medical University (No. 2022-004, dated on November 20, 2022). …”
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Protocol for a meta-review of interventions to prevent and manage ICU delirium by Andrew Booth, Maria Pufulete, Ben Gibbison, Burak Kundakci, Katherine Louise Jones

“…We will involve our Patient and Public Involvement group of people who experienced ICU delirium to develop and comment on such aspects as the research question, methodology and which outcomes are most important.Ethics and dissemination No ethical approval is required for this study. …”
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