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1821
Challenges Faced by Refugees in Kanungu: A Case Study of Matanda Campsite in Kanungu District Uganda.
Published 2024“…Qualitative data were analyzed by editing and reorganizing responses into concise, meaningful sentences, presented as quotations to complement quantitative findings. …”
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1822
GENOME POLITICS: STRATEGY AND TACTICS
Published 1999-01-01“…For better realization of information in some cases the genome changes the usual way of expression, that is, the genome uses some tactical approaches: at the DNA level - restructuring of the genome (mating type in yeasts, sex determination in some flies and worms, V(D)J recombination in immunoglobulin genes in human B lymphocytes); at the RNA level - gene splicing, alternative and self splicing, RNA editing; at the protein level - protein splicing. …”
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1823
Prevalence of Neonatal Sepsis and Associated Factors among Neonates in Neonatal Intensive Care Unit at Selected Governmental Hospitals in Shashemene Town, Oromia Regional State, Et...
Published 2018-01-01“…Then the collected data was coded and entered in to SPSS for windows version 20.0 for cleaning, editing, and analysis. Binary and multiple logistic regressions have been used to observe the association between independent variables and dependent variable. …”
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1824
Small open reading frames (sORFs): Driving big improvements in plant development and quality
Published 2025-03-01“…The synergistic application of sORFs with gene editing technologies holds great promise, not only for devising novel strategies to improve plant quality, resulting in crops that are more resistant, nutrient-rich, and productive, but also for establishing innovative molecular breeding pathways. …”
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1825
Generation of donor organs in chimeric animals via blastocyst complementation
Published 2020-12-01“…The proposed technology is the interspecific blastocyst complementation method in combination with genomic editing for obtaining “free niches” and pluripotent stem cell production methods. …”
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1826
Increased distribution of carbon metabolic flux during de novo cytidine biosynthesis via attenuation of the acetic acid metabolism pathway in Escherichia coli
Published 2025-02-01“…To mitigate carbon source loss, the CRISPR-Cas9 gene-editing technique was employed to knock out the poxB and pta genes in E. coli, generating the engineered strains K12ΔpoxB and K12ΔpoxBΔpta. …”
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1827
Pyridoxal-5′-Phosphate Promotes Immunomodulatory Function of Adipose-Derived Mesenchymal Stem Cells through Indoleamine 2,3-Dioxygenase-1 and TLR4/NF-κB Pathway
Published 2019-01-01“…Adipose-derived mesenchymal stem cells (A-MSCs) are promising cellular therapies for the treatment of immune-mediated diseases. Non-gene editing technologies can improve the immune regulatory function of A-MSCs. …”
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1828
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1829
From Dickens’s Theatrical Performance to Contemporary post Dickensian Narrative and Artistic Performance (Acker, Ackroyd, Waters and Rushdie)
Published 2010-06-01“…It is the author’s versatility (implied as he was in a whole range of activities: fiction-writing, editing, journalism, publishing initiatives, amateur theatricals, speeches, public readings, business undertakings and so forth), together with the plurality within his works (the neo-baroque effect, perceptible among other things through the so-called “streaky bacon” or the “wonderful gargoyles”), which have served as a springboard for contemporary fiction-writers. …”
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1830
Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
Published 2025-01-01“…Bacteria have advantages such as rapid proliferation, diverse gene editing methods, mature cultivation techniques, and relatively easy preparation of bacterial EVs (BEVs), which can be used to effectively address the challenges currently encountered in the field of EVs. …”
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1831
Advancements in cellular immunotherapy: overcoming resistance in lung and colorectal cancer
Published 2025-02-01“…The review also explores cutting-edge strategies aimed at overcoming resistance, including combination therapies, gene editing technologies, and nanotechnology for targeted drug delivery. …”
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1832
Extent, causes, and consequences of small RNA expression variation in human adipose tissue.
Published 2012-01-01“…We identified three genetic variants and three RNA editing events. Highly expressed small RNAs are more conserved within mammals than average, as are those with highly variable expression. …”
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1833
Removing limitations surrounding terpenoid biosynthesis by biotechnological techniques in Ferula sp.: A review
Published 2025-03-01“…This review examines the potential of hairy root culture, CRISPR/Cas-mediated genome editing, and metabolic engineering, including gene overexpression and enzyme engineering, for enhancing Ferula capacity tailored to industrial and medicinal needs. …”
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1834
De novo assembly of the mitochondrial genome of Glycyrrhiza glabra and identification of two types of homologous recombination configurations caused by repeat sequences
Published 2025-01-01“…We predicted 460 potential RNA editing sites, primarily involving cytosine-to-uracil transitions. …”
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1835
<i>Macrostomum lignano</i> as a model to study the genetics and genomics of parasitic flatworms
Published 2021-03-01“…All this makes M. lignano amenable to the most modern approaches of forward and reverse genetics, such as transposon insertional mutagenesis and methods of targeted genome editing by the CRISPR/Cas9 system. Due to the availability of an increasing number of genome and transcriptome assemblies of different parasitic flatworm species, new knowledge generated by studying M. lignano can be easily translated to parasitic f latworms with the help of modern bioinformatic methods of comparative genomics and transcriptomics. …”
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1836
A parallel bioreactor strategy to rapidly determine growth-coupling relationships for bioproduction: a mevalonate case study
Published 2025-01-01“…However, this process also led to the formation of the toxic byproduct acetate, which can slow growth and cause problems during downstream processing. By using gene editing to knock out the ackA-pta operon and poxB from E. coli BW25113, we were able to achieve the same optimum production rate, without the formation of acetate. …”
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1837
Quality assessment of fish vaccine data in the Norwegian Veterinary Prescription Register (VetReg)
Published 2025-01-01“…We identified specific issues that required manual editing of the units of 1 percent of the records. …”
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1838
Recent Developed Strategies for Enhancing Chondrogenic Differentiation of MSC: Impact on MSC-Based Therapy for Cartilage Regeneration
Published 2021-01-01“…This review provides an overview of recent advances in enhancement strategies for MSC chondrogenic differentiation, including optimization of bioactive factors, culture conditions, cell type selection, coculture, gene editing, scaffolds, and physical stimulation. This review will aid the further understanding of the MSC chondrogenic differentiation process and enable improvement of MSC-based cartilage tissue engineering.…”
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1839
High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models
Published 2025-01-01“…We used CRISPR genome-editing to create 25 worm models of human Mendelian diseases and phenotyped them using a single standardised assay. …”
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1840
Understanding Rett Syndrome: Genetic, clinical and therapeutic perspectives - literature review
Published 2025-01-01“…Recent studies show positive effects of trofinetide treatment, and gene therapy, genome editing and ataluren promise to be a promising treatment for RTT. …”
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