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    Retinoblastoma-binding Protein 9 Suppresses Intestinal Inflammation and Inflammation-induced Tumorigenesis in MiceSummary by Kensuke Hamada, Yuki Nakanishi, Yu Muta, Mayuki Omatsu, Kosuke Iwane, Munehiro Ikeda, Jiayu Chen, Yoko Masui, Naoki Aoyama, Nobukazu Agatsuma, Go Yamakawa, Takahiro Utsumi, Hiroki Kitamoto, Makoto Okabe, Yoshiro Itatani, Takumi Adachi, Koubun Yasuda, Shuji Yamamoto, Akihisa Fukuda, Etsushi Kuroda, Masaki Ohmuraya, Kazutaka Obama, Seiichi Hirota, Hiroki Ikeuchi, Kenji Nakanishi, Hiroshi Seno

    Published 2025-01-01
    “…Background & Aims: Retinoblastoma-binding protein 9 (RBBP9) was initially reported as cell cycle regulator via RB/E2F. Accumulating evidence has revealed the importance of RBBP9 in physiological and pathological states including inflammatory disease. …”
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    Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity by Pereira AP, Janela D, Areias AC, Molinos M, Tong X, Bento V, Yanamadala V, Cohen SP, Correia FD, Costa F

    Published 2025-01-01
    “…Netter School of Medicine, Hamden, Connecticut, USA; 4Department of Neurosurgery, Hartford Healthcare Medical Group, Westport, Connecticut, USA; 5Northwestern Feinberg School of Medicine, Chicago, Illinois, USA; 6Walter Reed National Military Medical Center, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA; 7Neurology Department, Centro Hospitalar E Universitário Do Porto, Porto, Portugal*These authors contributed equally to this workCorrespondence: Fabíola Costa, Sword Health Inc, 13937 Sprague Lane Ste 100, Draper, UT, 84020, USA, Tel +1 385-308-8034, Fax +1 801-206-3433, Email f.costa@swordhealth.comBackground: Obesity is a known risk factor and aggravator of musculoskeletal (MSK) conditions. …”
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    Effect of Slit3 on kidney fibrosis in diabetic kidney disease rats by Huang Ming-fang, Dong Yang, Shadek-jiang Harinul, Gan Xin-yu, Shi Wen-li, Lu Chen

    Published 2025-01-01
    “…Hematoxylin and eosin (H&E) staining was used to observe the histopathological changes of the kidney. …”
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    Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone by Shujing GUO, Li ZHANG

    Published 2025-01-01
    “…Among the natural environment types, water area (LCZ G) has the lowest average value of high temperature disaster risk, which indicates that water can effectively mitigate the risk of high temperature disaster; while for bare rock (LCZ E), exposed sand (LCZ F), and construction building (LCZ H) exposed outdoor, they typically have higher values of high temperature disaster risk due to solar radiation for a long time. …”
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