Eye Collateral Channel Characteristic Analysis and Identification Model Construction of Mild Cognitive Impairment by WU Tiecheng, CAO Lei, YIN Lianhua, HE Youze, LIU Zhizhen, YANG Minguang, XU Ying, WU Jinsong

“…Using the general demographic data sheet, neuro-psychological test scale, syndrome identification system of TCM and Boao visual diagnosis instrument, basic information, cognitive test results, and information on eye collateral channel characteristics and TCM symptom elements of the subjects were collected. …”
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Early Recognition and Intervention in SIBlingS at High Risk for Neurodevelopment Disorders (ERI-SIBS): a controlled trial of an innovative and ecological intervention for siblings... by Silvia Annunziata, Giulia Purpura, Giulia Purpura, Elena Piazza, Paolo Meriggi, Gabriele Fassina, Laura Santos, Emilia Ambrosini, Antonella Marchetti, Antonella Marchetti, Federico Manzi, Federico Manzi, Davide Massaro, Davide Massaro, Andrea Luna Tacci, Andrea Luna Tacci, Elisabetta Bolognesi, Simone Agostini, Francesca La Rosa, Alessandra Paola Giulia Pedrocchi, Paola Molina, Anna Cavallini

“…All recruited children will be evaluated at three different time points (T0 within the 8 months of life of the child, T1 after 6 months and T2 after 12 months) using behavioural, technological, and biological techniques to assess infants’ neurodevelopmental functions, parent-infant interaction, and early ASD markers.DiscussionThe ERI-SIBS study will expand knowledge regarding the impact of early intervention on families of infants at risk of neurodevelopmental disorders for the presence of a child with a diagnosis of ASD. The study will have the potential to significantly contribute to future research and the scientific and clinical debate on the best way to implement early intervention in at-risk populations. …”
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A Case of Euthyroid Graves’ Ophthalmopathy in a Patient Sero-Negative for TSH Receptor Autoantibody by Asami Hotta, Tomohiro Tanaka, Haruka Kato, Shota Kakoi, Yuki Shimizu, Chie Hasegawa, Akiko Hayakawa, Satoshi Yasuda, Kento Ogawa, Shunsuke Ito, Hideomi Ohguchi, Takashi Yagi, Hiroyuki Koyama, Mihoko Kawamura, Kazuhiko Sugitani, Yuichiro Ogura, Takashi Joh, Kenro Imaeda

“…This case gives insights into the potential pathophysiologic mechanism underlying Graves’ ophthalmopathy and casts light upon the difficulties of establishing the diagnosis in a euthyroid case with minimal positive results for anti-thyroid autoantibodies.…”
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Peripheral blood biomarkers as differential diagnostic markers of disease severity in neonates with hyperbilirubinemia by Dereje Mengesha Berta, Negesse Cherie, Berhanu Woldu, Aregawi Yalew, Elias Chane, Amare Mekuaninnit, Mebratu Tamir, Zufan Yiheyis, Abiy Ayele Angelo, Zewudu Mulatie, Adamu Kassie, Bisrat Birke Teketelew

“…However, they are not practically used for the differential diagnosis of the hyperbilirubinemia severity. Therefore, the current study aimed to assess the differential diagnostic value of peripheral blood biomarkers with disease severity as an alternative. …”
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Hospital attendance, malaria prevalence and self-medication with an antimalarial drug before and after the start of COVID-19 pandemic in a sentinel site for malaria surveillance in... by Denise Patricia Mawili-Mboumba, Fanny Bertrande Batchy Ognagosso, Noé Patrick M’Bondoukwé, Jacques Mari Ndong Ngomo, Bridy Chesly Moutombi Ditombi, Ahmed Adissa Agbanrin, Tatiana Nymane, Bedrich Pongui Ngondza, Reinne Moutongo Mouandza, Coella Joyce Mihindou, Dimitri Ardin Mabika Moussavou, Ornella Anaïse Mbang Nguema, Marielle Karine Bouyou-Akotet

“…Census of files of patients below 18 years of age attending for fever management with a result of malaria biological diagnosis from January 2018 to December 2022 was conducted. …”
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Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol by Akrita Bhatnagar, Monica Pernia Marin, Jonathan W. Lischalk, Min Ji Koh, Siviero Agazzi, Simeng Suy, Brent T. Harris, Susmeeta T. Sharma, Edward Aulisi, Amjad Anaizi, Mohamed H. Khattab, Walter C. Jean, Walter C. Jean, Sean P. Collins, Brian T. Collins

“…All underwent primary resection at the time of diagnosis. The indication for radiosurgery was tumor progression (n = 14, 70%) or residual tumor after subtotal resection (n = 6, 30%). …”
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Social determinants of mental health in asthma: an exploratory study by Sarah A. Hiles, Sarah A. Hiles, Hayley Lewthwaite, Hayley Lewthwaite, Vanessa L. Clark, Vanessa L. Clark, Anne E. Vertigan, Anne E. Vertigan, Anne E. Vertigan, Amber Smith, Amber Smith, Vanessa M. McDonald, Vanessa M. McDonald, Vanessa M. McDonald

“…The aim of the current exploratory study was to examine how social determinants are associated with depression, anxiety and resilience in people with mild-moderate and severe asthma.MethodsA cross-sectional study of 144 adults (aged ≥18 years) with a diagnosis of asthma was conducted. Participants were classified as having mild-moderate asthma or severe asthma based on international guidelines. …”
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AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“…Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection remains challenging due to its insidious symptoms. …”
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Predictive factors of thrombosis during autologous stem cell transplantation in multiple myeloma: Experience from EHU Oran (Algeria) by Mohammed Amine BEKADJA, Brahim BENZINEB, Mansour BELKACEM, Hafida OUDJERIOUAT, Badra ENTASOLTAN, Soufi OSMANI, Kamila AMANI, Samira BOUCHAMA, Leila CHAREF, Mohamed BRAHIMI, Abdessamad ARABI, Rachir Amar BOUHASS, Nabil YAFOUR

“…Methods-This is a retrospective study covering a period from 2009 to 2019. The diagnosis of thrombosis is made on the basis of clinical signs and symptoms of thrombosis and confirmed by a Doppler ultrasound of the site of location concerned or an angio-scanner, in the case of suspicion of arterial embolism, as well as D-Dimer elevation. …”
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Anticholinergic burden and behavioral and psychological symptoms in older patients with cognitive impairment by Sabrina Pistorio, Gianluca Scotto di Tella, Vittoria Canzanella, Raffaella Merenda, Gianluigi Cuomo, Paola Iacotucci, Vincenzo Carnovale, Leonardo Bencivenga, Maria Vargas, Annalaura Manes, Mauro Cataldi, Giuseppe Rengo, Giuseppe Rengo, Michela Zanetti, Grazia Daniela Femminella, Grazia Daniela Femminella

“…The aim of this research is to report use of anticholinergic drugs in a clinical population and to investigate the correlation between the use of anticholinergic drugs and the risk of presenting with more severe behavioral and psychological symptoms (BPSD).MethodPatients with a diagnosis of subjective cognitive impairment, mild cognitive impairment (MCI) or dementia were recruited. …”
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The prevalence of hand pathology in regional orthopaedic hospitals in KwaZulu-Natal: A cross-sectional study by S Thabit, M O'Connor, W Parker, T Mashishi, K Moodley, A Peer, K Matanzima, A J de Villiers, O Adewusi, R Aboobaker, A Rocher

“…For HP patients, additional detail was collected regarding diagnosis, mechanism, admission and management. The prevalence of HP was calculated as a factor of all orthopaedic presentations. …”
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Integration analysis of microRNAs as potential biomarkers in early-stage lung adenocarcinoma: the diagnostic and therapeutic significance of miR-183-3p by Guodong Huang, Yuxia Liu, Lisha Li, Bing Li, Ting Jiang, Yufeng Cao, Xiaoping Yang, Xinning Liu, Honglin Qu, Shitao Li, Xin Zheng

“…IntroductionLung adenocarcinoma (LUAD) poses a significant therapeutic challenge, primarily due to delayed diagnosis and the limited efficacy of existing treatments.MethodsTo understand the pathogenesis and identify diagnostic biomarkers for LUAD in the early stage, we investigated differential miRNA expression in 33 stage I LUAD patients between tumor and matched paracancerous tissues by Illumina Sequencing. …”
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Real-world experience with nucleos(t)ide analogue therapy and patient survival rates in chronic viral hepatitis B treatment centers in Eritrea by Michael Berhe Solomon, Ghirmay Ghebrekidan Ghebremeskel, Oliver Okoth Achila, Aron Rezene Mebrahtu, Mohammed Elfatih Hamida, Araia Berhane Mesfin

“…A total of 413 patients with HBV (median age (IQR) at diagnosis: 39 (IQR: 28–50 years; females: 118(28.6%); followed for a total of 22,921 person days) were studied. …”
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Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study by Eshetie Melese Birru, Kevin T. Batty, Laurens Manning, Stephanie L. Enkel, Brioni R. Moore

“…. • Recommendations to address identified challenges include (a) improved training/education on RHD diagnosis, disease progression, and treatment, (b) improved access to supportive resources, (c) active adverse reaction monitoring and reporting, and (d) encouraging the provision/access of globally subsidized BPG suspension formulations in pre-filled syringes.…”
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Risk of Coronary Heart Disease among HIV-Infected Patients: A Multicenter Study in Brazil by Sandra C. Fuchs, Paulo R. Alencastro, Maria Letícia R. Ikeda, Nêmora T. Barcellos, Fernando H. Wolff, Ajácio B. M. Brandão, Ricardo A. A. Ximenes, Demócrito de B. Miranda-Filho, Heloísa Ramos Lacerda, Maria de Fátima P. M. de Albuquerque, Ulisses Ramos Montarroyos, Max W. Nery, Marilia D. Turchi

“…The use of antiretroviral agents and time since HIV diagnosis were not risk factors for coronary artery disease in 10 years. …”
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Investigation on nursing needs of patients in the Traditional Chinese Medicine Famous-Doctor clinic and countermeasures (中医名医堂门诊患者护理需求调查及对策分析)... by MI Wei (米薇), SHU Baozhen (舒宝珍), TANG Ling (唐玲), WANG Huaxin (王华新), ZHANG Yongli (张永丽)

“…The reasons why the patients chose the TCM Famous Doctor clinic were analyzed from seven aspects to investigate and analyze the satisfaction of nursing services currently provided, such as treatment environment, diagnosis process, accurate triage, enthusiastic service, initiative service, communication ability professional knowledge. …”
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Prevalence and molecular characterization of human bocavirus-1 in children and adults with influenza-like illness from Kunming, Southwest China by Yanhong Sun, Lili Jiang, Yaoyao Chen, Zhaosheng Liu, Meiling Zhang, Xiaonan Zhao, Xiaoyu Han, Lifen Zhang, Xiaoqing Fu, Jienan Zhou

“…Understanding the prevalence and molecular characteristics of HBoV-1 in individuals with influenza-like illness (ILI) is essential for enhancing the diagnosis and treatment of respiratory infections in Kunming, Southwest China. …”
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Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus by Maofei Zhu, Maofei Zhu, Yueming Chu, Yueming Chu, Qiang Yuan, Qiang Yuan, Junfeng Li, Silin Chen, Lin Li, Lin Li, Lin Li

“…Therefore, a deeper understanding of the therapeutic targets and the mechanisms underlying its occurrence and development is of great importance for early diagnosis, identification of potential therapeutic agents and improvement of the prognosis for patients.MethodsFirstly, the dataset of SCCE was downloaded from the GEO database and GEO2R tool was employed for the analysis of differentially expressed genes (DEGs). …”
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Current data on the circulation of the Q fever pathogen in the Republic of Guinea by Ekaterina V. Naidenova, Kirill S. Zakharov, Dmitry A. Agafonov, Mikhail Yu. Kartashov, Aislu M. Senichkina, Erik S. Khalilov, Abdoul B. Ibrahim, Mamadou B. Bah, Ibrahim Nourdine, Nikolai K. Tokarevich, Sanaba Boumbaly, Yusuf Sidime, Svetlana A. Shcherbakova, Vladimir V. Kutyrev

“…Regular monitoring and assessment of risk factors for diseases caused by coxiella are necessary for the development of an algorithm for laboratory diagnosis and recommendations for clinicians.…”
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Early initiation of intravenous cyclophosphamide and one‐year outcome in super‐refractory cryptogenic‐new onset refractory status epilepticus by Yasufumi Yorichika, Shuichiro Neshige, Hideaki Sakahara, Narumi Ono, Megumi Nonaka, Yuichiro Tagane, Tomoaki Watanabe, Keisuke Tachiyama, Haruka Ishibashi, Masahiro Nakamori, Takeo Shishido, Shiro Aoki, Hiroki Ueno, Yu Yamazaki, Takahiro Iizuka, Hirofumi Maruyama

“…Despite initiating antiseizure medications (ASMs) and first‐line immunotherapy (intravenous‐methylprednisolone and immunoglobulins) within a median of 3 days from onset, SE persisted >5 days. The diagnosis of C‐NORSE was suggested based on a high C‐NORSE score (6/6). …”
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