Ketamine Infusion as an Adjunct to Opioid Analgesia in Pediatric Patients with High-Risk Neuroblastoma Undergoing Treatment with Dinutuximab: Adverse Effects and Safety in a Non-IC... by Streby KA, Tobias JD, McPhaden E, Downie S, Stanek J, Roth C, Patel PO

“…Linear mixed effect regression was used to model IVMME use for pain management across dinutuximab cycles and explore the effect of ketamine.Results: The study cohort included 187 dinutuximab hospitalizations from 40 patients. Age at diagnosis ranged from 1.2 to 11.4 years. 66/187 hospitalizations included ketamine. …”
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The Role of Rotational Thromboelastometry in Early Detection of the Hemostatic Derangements in Neonates with Systemic Candida Infection by Rozeta Sokou, Alexia Eleftheria Palioura, Aikaterini Konstantinidi, Alexandra Lianou, Maria Lampridou, Martha Theodoraki, Daniele Piovani, Stefanos Bonovas, Konstantina A. Tsante, Petros Ioannou, Nicoletta Iacovidou, Andreas G. Tsantes

“…The results of this study highlight the need for monitoring of hemostatic status of this vulnerable group of patients and indicate that ROTEM analysis may have a role in the early detection of the hemostatic derangements associated with SCI in neonates, in order to ensure timely diagnosis and targeted therapeutic intervention.…”
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OBSERVATION OF THE NORMAL DEVELOPMENTAL PATTERN OF FETAL CEREBRAL SULCI BETWEEN 18 TO 32 WEEKS OF GESTATIONAL AGE BY USING ULTRASONOGRAPHY - A CORRELATIONAL STUDY BETWEEN TWO MATER... by Sujith Kumar Reddy Madithati, Sai Shankar Mankuzhy Gopalakrishnan, Santosh Chandrasekhar, Jenikar Paulraj, Archana Bala, Geeta Shankar

“…This is a Cross-sectional observational study, performed among 110 antenatal women investigated under the Department of Radio Diagnosis, Shri Sathya Sai medical college and research institute, Ammapettai. …”
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Functional MRI study of neurovascular coupling in patients with non-lesional epilepsy by Zhisen Li, Xiaoxia Hou, Yanli Lu, Huimin Zhao, Meixia Wang, Qian Gui, Guanhui Wu, Qinrong Xu, Xiaofeng Dong, Qingzhang Cheng, Xiaowen Xu, Hongxuan Feng

“…ObjectiveThe diagnosis of patients with non-lesional epilepsy (NLE) is relatively challenging because of the absence of a clear focus on imaging, and the underlying pathological mechanism remains unclear. …”
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Mycobiome analyses of critically ill COVID-19 patients by Danielle Weaver, Sara Gago, Matteo Bassetti, Daniele Roberto Giacobbe, Juergen Prattes, Martin Hoenigl, Florian Reizine, Hélène Guegan, Jean-Pierre Gangneux, Michael John Bromley, Paul Bowyer

“…There was no significant association with corticosteroid use or CAPA diagnosis and respiratory fungal communities. Increased A. fumigatus burden was associated with mortality and, the use of azoles at ICU admission was linked with an absence of A. fumigatus. …”
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Special aspects of the clinical course and replacement therapy peculiarities in a patient with autoimmune polyglandular syndrome type 1: a clinical case by Maria G. Pavlova, Olga O. Golounina, Tatyana B. Morgunova, Natalya V. Likhodey, Marina F. Kalashnikova, Aleksandr G. Farmanov, Tamriko D. Khazaliya, Valentin V. Fadeev

“…., 28 years old, was followed up for 10 years in the Endocrinology clinic with the diagnosis of “Autoimmune polyglandular syndrome type 1. …”
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Counting the cost of hospitalised injury using administrative data in Australia: three considerations from a retrospective cohort data linkage study by Jacelle Warren, Kirsten Vallmuur, Victoria McCreanor, Steven M McPhail, Shahera Banu, Michael Schuetz, Clifford Afoakwah

“…Objectives To examine the relative differences in injury hospitalisation cost estimates from hospital administrative data when using (1) hospital reimbursement based on National Efficient Price (NEP) versus local hospital costings methods, (2) inflation factors based on Consumer Price Index (CPI) versus health group index and (3) different healthcare funder’s perspectives.Design Retrospective population-based cohort study of linked Queensland Hospital Admitted Patient Data Collection dataset and National Hospital Cost Data Collection data.Setting All admitted injury-related care episodes occurring within a major trauma hospital in Queensland during 1 January 2012 to 31 December 2017.Outcome measure Total in-patient hospitalisation cost associated with an episode of care.Results Injury without catastrophic/severe complications or comorbidities was the most frequently occurring Australian Refined Diagnosis-Related Groups (AR-DRG) over the 6-year period, while rehabilitation with catastrophic complications or comorbidities was the most expensive ($37 938, 95% CI $36 067 to $39 809). …”
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Gastroblastoma in Adulthood—A Rarity among Rare Cancers—A Case Report and Review of the Literature by Giovanni Centonze, Alessandro Mangogna, Tiziana Salviato, Beatrice Belmonte, Laura Cattaneo, Melissa Anna Teresa Monica, Giovanna Garzone, Cecilia Brambilla, Alessio Pellegrinelli, Flavia Melotti, Adele Testi, Valentina Monti, Ketevani Kankava, Patrizia Gasparini, Gianpaolo Dagrada, Vincenzo Mazzaferro, Christian Cotsoglou, Paola Collini, Giancarlo Pruneri, Massimo Milione

“…Hence, GB should be considered in the differential diagnosis of microscopically comparable conditions in adults carrying a worse prognosis and different clinical approach.…”
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Healthcare performance of leprosy management in peripheral health facilities of Dhanusa and Mahottari, Nepal by Ram Kumar Mahato, Uttam Ghimire, Bijay Bajracharya, Binod K. C., Deepak Bam, Deepak Ghimire, Uttam Raj Pyakurel, David T. S. Hayman, Basu Dev Pandey, Chuman Lal Das, Krishna Prasad Paudel

“…Nepal’s leprosy elimination program depends on early case diagnosis and the performance of health workers and facilities. …”
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Optimization of the management of pregnant women with new COVID-19 coronavirus infection: An open prospective cross-sectional study by Irina V. Medyannikova, Yuliya Ch. Kuklis, Irina V. Saveljeva, Galina B. Beznoshchenko, Elena G. Galyanskaya, Olga Yu. Tsygankova, Galina V. Krivchik, Elena A. Bukharova, Natalya V. Nosova, Pavel V. Davidov

“…Improving the management of pregnant women with COVID-19 by identifying a high-risk group for gestational complications, based on their early diagnosis, timely delivery, and use of acetylsalicylic acid and endotheliotropic agents to prevent venous thromboembolic complications, in addition to the standard of care, reduces the frequency of placental disorders by 2.3 times, severe preeclampsia – by 2.9 times, premature birth at 28–37 weeks – by 2 times, surgical delivery by cesarean section – by 1.6 times, delivery of low birth weight newborns – by 2.3 times, hospitalization in the intensive care unit of newborns – by 2.5 times.…”
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Incidence and predictors of adverse birth outcomes among women who gave birth at Assosa general hospital, Northwest Ethiopia: a retrospective cohort study by Habtamu Tadesse Gudeta, Shalama Lekasa Nagari, Dessalegn Emana Jabana, Mustefa Aflegn Legese, Demekisa wondimu Biyena, Fantahun Cheklie Kassie

“…Improving maternal health services, nutrition education, early diagnosis, and treatment can help to manage most of these predictors.…”
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Promotional tone in reviews of menopausal hormone therapy after the Women's Health Initiative: an analysis of published articles. by Adriane Fugh-Berman, Christina Pike McDonald, Alicia M Bell, Emily Catherine Bethards, Anthony R Scialli

“…Scientific accuracy was assessed based on whether or not the findings of the WHI were accurately reported using two criteria: (1) Acknowledgment or lack of denial of the risk of breast cancer diagnosis associated with hormone therapy, and (2) acknowledgment that hormone therapy did not benefit cardiovascular disease endpoints. …”
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Comparative Study on Associations Between Lung Cancer Prognosis and Diagnostic Criteria Set by the European Palliative Care Research Collaboration and the Asian Working Group for C... by Utae Katsushima, Takuya Fukushima, Jiro Nakano, Naoya Ogushi, Kazuki Fujii, Yutaro Nagata, Keisuke Kamisako, Yukiko Okuno, Yuta Okazaki, Kentaro Nakanishi, Kiyori Yoshida, Tatsuki Ikoma, Yuki Takeyasu, Yuta Yamanaka, Hiroshige Yoshioka, Kimitaka Hase, Takayasu Kurata

“…The association between cachexia diagnosis and prognosis was examined for each set of criteria using a Cox proportional hazards model. …”
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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

“…Objective Congestive heart failure (CHF) is a clinical syndrome in which the heart disease progresses to a severe stage. Early diagnosis and risk assessment of death of patients with CHF are critical to prognosis and treatment. …”
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Does tocilizumab eliminate inflammation in GCA? A cohort study on repeated temporal artery biopsies by Chiara Marvisi, Francesco Muratore, Carlo Salvarani, Pierluigi Macchioni, Pamela Mancuso, Luigi Boiardi, Stefania Croci, Paolo Giorgi Rossi, Alberto Cavazza, Annibale Versari, Rexhep Durmo, Caterina Ricordi, Martina Bonacini, Giuseppe Malchiodi

“…We aimed to evaluate the histological impact of adding tocilizumab (TCZ) to GCs.Methods We enrolled all consecutive GCA patients with an inflammed TAB at diagnosis who were treated with TCZ and GCs for ≥6 months and followed from December 2017 to December 2023. …”
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Сlinical case of funicular myelosis in combination with a concomitant genetic predisposition to folate cycle disorder by O.D. Shulga, E.A. Popko, A.S. Chabanova, O.G. Kotsiuba, Q. Hussain

“…According to the results of the literature analysis, additional markers for the diagnosis of funicular myelosis (in particular, homocysteine), the causes of hyper­homocysteinemia and its effects on the body were described. …”
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Obesity and polysomnographic variables on patients with obstructive sleep apnea by Chaiane Facco Piccin, Marco Colomé Beck, Luiz Carlos Alves de Oliveira, Reinaldo Fernando Cóser Neto, Pedro Luis Cóser, Fabrício Scapini, Antônio Marcos Vargas da Silva

“…Eighty eight patients were evaluated divided in eutrophic (EG; n=21; BMI=23.4±1.3kg/m2), overweight (OWG; n=34; BMI=27.5±1.4kg/m2) and obese group (OG; n=33; BMI=33.6±2.9kg/m2) that carried out all-night basal polysomnography for the diagnosis of Obstructive Sleep Apnea (OSA). The following variables were analyzed: stages 1, 2 and 3 of sleep (N1, N2 and N3), REM sleep, index peri- odic movements of the lower limbs (PLMS), apnea and hypopnea (AHI), AHI in REM sleep (AHIREM) and micro-arousal rates (MAR). …”
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Characteristics and contributing factors of adverse drug reactions: an analytical study of patients with tuberculosis receiving treatment under the National TB Program of India [ve... by Jay Patel, Priya Bhavsar, Harsh Shah, Sandul Yasobant, Deepak Saxena, Anish Sinha, Somen Saha, Yogesh Patel

“…Although the National Tuberculosis Elimination Program (NTEP) is providing a wide range of interventions from early diagnosis to complete treatment to reduce morbidity and mortality from TB, adverse drug reactions (ADR) remain a challenge in treatment adherence and completion. …”
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Upadacitinib in active non-radiographic axial spondyloarthritis: 2-year data from the phase 3 SELECT-AXIS 2 study by Filip Van den Bosch, Atul Deodhar, Denis Poddubnyy, Walter P. Maksymowych, Désirée van der Heijde, Tae-Hwan Kim, Mitsumasa Kishimoto, Xenofon Baraliakos, Xianwei Bu, Ivan Lagunes-Galindo, In-Ho Song, Peter Wung, Koji Kato, Anna Shmagel

“…Methods The study enrolled eligible adult patients with a clinical diagnosis of nr-axSpA who met the 2009 Assessment of SpondyloArthritis international Society (ASAS) classification criteria and had objective signs of active inflammation on magnetic resonance imaging (MRI) of sacroiliac joints and/or high-sensitivity C-reactive protein. …”
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How is infection diagnostic criteria for shoulder periprosthetic joint infection reported in literature: systematic review by Alexis L. Clifford, BS, Eoghan Hurley, MB, BCh, MCh, PhD, Dana Rowe, BA, Lulla Kiwinda, BS, Tom R. Doyle, MB, MCh, Bryan S. Crook, MD, Grant E. Garrigues, MD, Jason E. Hsu, MD, Thorsten M. Seyler, MD, PhD, Oke A. Anakwenze, MD, MBA, Christopher S. Klifto, MD

“…Background: The purpose of this study was to elucidate which criteria are being reported in the literature for the workup and diagnosis of shoulder periprosthetic joint infection (PJI). …”
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